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1. 发明授权

US09599542B2 Sample analyzing chip 有权
公开(公告)号：US09599542B2
公开(公告)日：2017-03-21
申请号：US14401140
申请日：2013-05-14
申请人： NANOENTEK, INC.
发明人： Dae Sung Hur , Jae Jeong Kim , Yu Rae Kim
IPC分类号： G01N35/08 , G01N1/00 , G01N33/48 , B01L3/00
CPC分类号： G01N1/00 , B01L3/502715 , B01L3/502723 , B01L3/502746 , B01L2200/027 , B01L2200/0684 , B01L2300/0816 , B01L2300/089 , B01L2400/086 , G01N33/48 , G01N35/08 , G01N2001/002
摘要： The present invention relates to a sample analyzing chip. The chip can prevent upper and lower substrates of a channel from being attached to each other due to deflection on a micro channel and can solve the problem of the sample drying up within a measuring time of a target. Also, the chip can prevent bubbles from being generated in a central portion of the micro channel.

2. 发明申请

US20140248197A1 SAMPLER 有权
标题翻译：取样器
公开(公告)号：US20140248197A1
公开(公告)日：2014-09-04
申请号：US14349368
申请日：2012-05-15
申请人： Dae Sung Hur
发明人： Dae Sung Hur
IPC分类号： G01N1/34
CPC分类号： G01N1/34 , A61B5/1405 , A61B5/150022 , A61B5/150343 , A61B5/150755 , B01L3/502753 , B01L2300/0681 , B01L2300/0809 , B01L2300/0832 , B01L2400/0406 , B01L2400/0478 , G01N33/491
摘要： The present invention relates to a sampler which is capable of rapidly and easily separating blood corpuscles from blood, being operated conveniently, and directly using extracted plasma. According to one embodiment of the present invention, a sampler includes a chamber and a membrane guide. Here, the chamber includes an insertion unit having an insertion hole on one side, wherein the other side is opened, and an inner side includes a receiving space for receiving a sample. Additionally, one side of the membrane guide is combined to the membrane, and the membrane guide includes a channel wherein filtered materials, which are filtered through the membrane among the samples received in the receiving space, are moved in a gravitational direction.
摘要翻译：本发明涉及一种能够快速，容易地将血液从血液中分离并且操作方便，并直接使用提取的等离子体的取样器。根据本发明的一个实施例，采样器包括腔室和膜引导件。这里，腔室包括在一侧具有插入孔的插入单元，其中另一侧被打开，并且内侧包括用于接收样品的容纳空间。此外，膜引导件的一侧与膜组合，并且膜引导件包括通道，其中在接收空间中接收的样品中通过膜过滤的过滤材料在重力方向上移动。

3. 发明申请

US20130243665A1 SAMPLER 有权
标题翻译：取样器
公开(公告)号：US20130243665A1
公开(公告)日：2013-09-19
申请号：US13990965
申请日：2011-12-01
申请人： Dae-Sung Hur , Ji-Young Park
发明人： Dae-Sung Hur , Ji-Young Park
IPC分类号： G01N1/38
CPC分类号： G01N1/38 , A61B5/14 , B01L3/0248 , B01L3/502 , B01L3/563 , B01L2200/0605 , B01L2300/046 , B01L2300/047 , B01L2300/0672 , B01L2300/0832 , B01L2300/0838 , B01L2400/0406 , B01L2400/0683
摘要： Disclosed therein is a sampler. The sampler includes: a chamber accommodating a fluid or solid reagent therein and being sealed at both ends with penetrable films; a tube joined with the chamber at one side, the tube having a hollow portion therein; and a movable bar having a tip which is formed at one end and has a specimen extracting portion, the tip being guided and moved through a hollow portion, the tip being adapted for mixing the specimen extracted by the specimen extracting portion with the reagent so as to form a diluted solution while penetrating through one end of the chamber and adapted for quantitatively discharging out the diluted solution while penetrating through the other end of the chamber.
摘要翻译：其中公开了采样器。采样器包括：容纳流体或固体试剂的室，并在两端用可渗透膜密封; 在一侧与腔室连接的管，其中具有中空部分的管; 以及可动杆，其具有在一端形成并具有样本提取部的尖端，所述尖端被引导并移动通过中空部，所述尖端适于将由所述检体提取部提取的样本与所述试剂混合，以在穿透室的一端时形成稀释溶液，并适于在渗透室的另一端时定量地排出稀释溶液。

4. 发明申请

US20130201322A1 FLUORESCENT MICROSCOPE FOR OBSERVING MULTIPLE FLUORESCENT IMAGES, FLUORESCENT IMAGE SURVEYING METHOD USING THE SAME, AND MULTIPLE FLUORESCENT IMAGE OBSERVING SYSTEM 有权
标题翻译：用于观察多个荧光图像的荧光显微镜，使用其的荧光图像测量方法和多个荧光图像观察系统
公开(公告)号：US20130201322A1
公开(公告)日：2013-08-08
申请号：US13809319
申请日：2011-08-18
申请人： Hwa Joon Park , Jeoung Ku Hwang , Jee Young Kim , Chan Il Chung
发明人： Hwa Joon Park , Jeoung Ku Hwang , Jee Young Kim , Chan Il Chung
IPC分类号： G02B21/00
CPC分类号： G02B21/0076 , G01N2021/6419 , G01N2021/6421 , G02B21/0064 , G02B21/16 , G02B2207/113
摘要： A fluorescent microscope for observing multiple fluorescent images includes: a first optical module comprising a first light source for supplying first excitation light having a first wavelength, a first excitation filter for selectively transmitting the first excitation light supplied from the first light source, a first dichroic filter for reflecting the first excitation light having passed through the first excitation filter toward the survey object, an objective lens for condensing the first excitation light reflected by the first dichroic filter and transferring the condensed first excitation light to the survey object, a second dichroic filter for reflecting first radiation light radiated from the survey object, a first radiation filter for selectively transmitting the first radiation light reflected by the second dichroic filter, and a first image acquisition unit for acquiring an image by using the first radiation light having passed through the first radiation filter to be supplied; and a second optical module comprising a second light source for supplying second excitation light having a second wavelength, a second excitation filter for selectively transmitting the second excitation light supplied from the second light source, a second radiation filter passing through the second excitation filter and irradiated to the survey object to be radiated, to selectively transmitting the second radiation light EM2 having passed through the objective lens, the first dichroic filter, and the second excitation filter, and a second image acquisition unit for acquiring an image by using the second radiation light having passed through the second radiation filter to be supplied.
摘要翻译：用于观察多个荧光图像的荧光显微镜包括：第一光学模块，包括用于提供具有第一波长的第一激发光的第一光源，用于选择性地透射从第一光源提供的第一激发光的第一激发滤光器，第一二色性滤光器，用于将通过第一激发滤光器的第一激发光朝向测量对象反射;物镜，用于会聚由第一分色滤光器反射的第一激发光并将聚集的第一激发光转印到测量对象;第二二向色滤光片用于反射从所述测量对象辐射的第一辐射光，用于选择性地透射由所述第二分色滤光器反射的所述第一辐射光的第一辐射滤光器;以及第一图像获取单元，用于通过使用已经穿过所述第一辐射过滤器为sup 合并以及第二光学模块，包括用于提供具有第二波长的第二激发光的第二光源，用于选择性地透射从第二光源提供的第二激发光的第二激发滤光器，穿过第二激发滤光器并照射的第二辐射滤光片到要被辐射的测量对象，以选择性地透过已经通过物镜的第二辐射光EM2，第一二向色滤光器和第二激发滤光器，以及第二图像获取单元，用于通过使用第二辐射光获取图像已通过要供应的第二辐射滤波器。

5. 发明授权

US10801931B2 Sample pretreatment system and control method therefor 有权
公开(公告)号：US10801931B2
公开(公告)日：2020-10-13
申请号：US15757551
申请日：2016-08-30
申请人： NANOENTEK, INC.
发明人： Hyoung-Seop Lee , Sung-Hun Hong
IPC分类号： G01N1/00 , G01N1/38 , G01N1/44 , B01F13/08 , G01N1/28 , H02N11/00 , G01N35/10 , B01L9/00 , B01L3/00 , G01N35/00
摘要： Disclosed are a system for pretreatment of sample and a method for controlling the same. The system for pretreatment of sample, including: a holder storage unit having a module holder on which a sample pretreatment module is seated; a cartridge accommodating portion for loading a cartridge therein, wherein the sample accommodated in a chamber of the sample pretreatment module is discharged and loaded into the cartridge; a magnetic force generating unit for generating a magnetic force to rotate the permanent magnet provided in the sample pretreatment module; and a penetration and discharge unit for penetrating the penetration membrane in the sample pretreatment module and discharging the sample by pressing the moving unit of the cap.

6. 发明申请

US20180259432A1 SAMPLE PRETREATMENT SYSTEM AND CONTROL METHOD THEREFOR 审中-公开
公开(公告)号：US20180259432A1
公开(公告)日：2018-09-13
申请号：US15757551
申请日：2016-08-30
申请人： NANOENTEK, INC.
发明人： Hyoung-Seop LEE , Sung-Hun HONG
IPC分类号： G01N1/38 , B01F13/08 , G01N1/44 , G01N35/10
摘要： Disclosed are a system for pretreatment of sample and a method for controlling the same. The system for pretreatment of sample, including: a holder storage unit having a module holder on which a sample pretreatment module is seated; a cartridge accommodating portion for loading a cartridge therein, wherein the sample accommodated in a chamber of the sample pretreatment module is discharged and loaded into the cartridge; a magnetic force generating unit for generating a magnetic force to rotate the permanent magnet provided in the sample pretreatment module; and a penetration and discharge unit for penetrating the penetration membrane in the sample pretreatment module and discharging the sample by pressing the moving unit of the cap.

7. 发明申请

US20180250645A1 SAMPLE PRETREATMENT MODULE AND PRETREATMENT METHOD USING THE SAME 审中-公开
公开(公告)号：US20180250645A1
公开(公告)日：2018-09-06
申请号：US15757523
申请日：2016-08-30
申请人： NANOENTEK, INC.
发明人： Yu-Rae KIM
IPC分类号： B01F13/08 , G01N1/38 , H02N11/00 , B01L3/00
摘要： Disclosed are a sample pretreatment module and a sample pretreatment method using the same. The sample pretreatment module including: a body having a chamber for accommodating a sample therein; a cap coupled to one end of the body; a dotting substrate provided to have at least some portion of it dotted with the reagent and be inserted into the chamber; a discharge tip movably coupled to the other end of the body for discharging a sample accommodated in the chamber; a permanent magnet provided to be inserted in the chamber and mix the sample by rotating owing to a magnetic force acting in accordance with a change in a magnetic field externally applied; and a moving unit movably provided in the cap and pressing the sample in the chamber according to the movement to discharge the sample to the outside.

8. 发明申请

US20170184572A1 NOVEL METHOD FOR DETECTING DETECTION OBJECT IN SAMPLE, AND DETECTION KIT USING SAME 审中-公开
公开(公告)号：US20170184572A1
公开(公告)日：2017-06-29
申请号：US15313382
申请日：2015-05-22
申请人： NANOENTEK, INC.
发明人： Joon Seok SEO , Kyu Hwan SHIM
IPC分类号： G01N33/533 , G01N33/53 , C12Q1/68 , G01N33/74
CPC分类号： G01N33/533 , C12Q1/68 , G01N33/53 , G01N33/54306 , G01N33/74
摘要： The present invention relates to a novel method for detecting a detection object in a sample, and a detection device using the same. The detecting method of the present invention uses a “bridge composite” in which gold nanoparticles and an antibody specific to a detection object are coupled in order to induce a sufficient coupling reaction between the antibody and the detection object, thereby improving reactivity. Accordingly, since excellent resolution is provided, the method of the present invention has advantages of enabling accurate concentration measurement of a detection object in a sample, and amplifying a measurement signal. In addition, the method of the present invention can effectively detect small molecules such as hormones, vitamins, etc. having a small molecular weight.

9. 发明授权

US08858897B2 Microfluidic chip for analysis for fluid sample 有权
标题翻译：用于流体样品分析的微流控芯片
公开(公告)号：US08858897B2
公开(公告)日：2014-10-14
申请号：US12667372
申请日：2008-11-21
申请人： Hyun Chang Lim , Jun Ha Park , Chang Seop Lee , Hyun Joo Jung , Ji Young Park , Chan Il Chung , Jun Keun Chang
发明人： Hyun Chang Lim , Jun Ha Park , Chang Seop Lee , Hyun Joo Jung , Ji Young Park , Chan Il Chung , Jun Keun Chang
IPC分类号： B01L99/00 , B01L3/00 , G01N35/00 , G01N33/53
CPC分类号： G01N35/00029 , B01L3/502723 , B01L3/502746 , B01L2300/0825 , B01L2300/087 , B01L2300/089 , B01L2400/0406 , B01L2400/086 , G01N33/5304 , G01N2035/00158
摘要： Disclosed is a microfluidic chip capable of accurately and quickly detecting presence of a trace amount of a target within a fluid sample. It has a channel structure comprising a sample inlet for feeding a sample therethrough, a first reservoir for primarily storing the sample therein, a second reservoir for secondarily storing the sample therein, a first reaction portion in which a target is conjugated with a label, a second reaction portion in which the labeled target undergoes a specific reaction, such as an antigen-antibody reaction, and a delaying portion, located between the first and the second reaction portion, for decreasing a flow rate of the sample.
摘要翻译：公开了一种能够准确且快速地检测流体样品中痕量痕量目标的微流控芯片。它具有通道结构，该通道结构包括用于将样品通过其中的样品入口，用于主要将样品储存在其中的第一储存器，用于在其中二次存储样品的第二储存器，其中靶标与标签共轭的第一反应部分，第二反应部分，其中标记的靶经历诸如抗原 - 抗体反应的特异性反应，以及位于第一和第二反应部分之间的延迟部分，用于降低样品的流速。

10. 发明申请

US20130064714A1 CHIP FOR FLUID ANALYSIS 审中-公开
标题翻译：流体分析芯片
公开(公告)号：US20130064714A1
公开(公告)日：2013-03-14
申请号：US13698697
申请日：2011-05-17
申请人： Dae Sung Hur , Ji Young Park
发明人： Dae Sung Hur , Ji Young Park
IPC分类号： G01N21/64
CPC分类号： B01L3/502715 , B01L3/502746 , B01L7/00 , B01L2200/027 , B01L2200/028 , B01L2300/0816 , B01L2300/0822 , B01L2300/0825 , B01L2300/0864 , B01L2300/1805 , B01L2400/0406
摘要： Disclosed herein is a chip for analyzing fluids which restricts the flow of a fluid and the flow velocity of the fluid at a reaction unit, where an antigen-antibody reaction occurs, to increase reactivity and sensitivity.
摘要翻译：本文公开了一种用于分析流体的芯片，其限制流体的流动和在发生抗原 - 抗体反应的反应单元处的流体的流速，以增加反应性和灵敏度。

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