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1. 发明申请

US20100151029A1 Anti-infectious hydrogel compositions 审中-公开
标题翻译：抗感染性水凝胶组合物
公开(公告)号：US20100151029A1
公开(公告)日：2010-06-17
申请号：US12658937
申请日：2010-02-16
申请人： Rainer Gruening , Doug J. Perschbacher , Xin Qu , David Buongiovanni
发明人： Rainer Gruening , Doug J. Perschbacher , Xin Qu , David Buongiovanni
IPC分类号： A61K9/00 , A61K31/787 , A61P31/00
CPC分类号： A61K31/785 , A61K9/0019 , A61K47/32 , A61K47/36
摘要： The present invention provides a hydrogel composition capable of preventing the intrusion of micro-organisms into body cavities or body openings of mammals comprising of a poly(N-vinyl lactam), a polysaccharide and water.
摘要翻译：本发明提供了能够防止微生物侵入包含聚（N-乙烯基内酰胺），多糖和水的哺乳动物的体腔或身体开口的水凝胶组合物。

2. 发明授权

US5851540A Composition, barrier film, and method for preventing contact dermatitis 失效
标题翻译：组合物，阻隔膜和预防接触性皮炎的方法
公开(公告)号：US5851540A
公开(公告)日：1998-12-22
申请号：US824282
申请日：1997-03-26
申请人： Joan Dalla Riva Toma , Curtis L. Karl
发明人： Joan Dalla Riva Toma , Curtis L. Karl
IPC分类号： A61K8/60 , A01N25/00 , A01N25/34 , A61K6/00 , A61K8/00 , A61K8/20 , A61K8/33 , A61K8/39 , A61K8/40 , A61K8/49 , A61K8/72 , A61K8/73 , A61K31/00 , A61K31/085 , A61K31/70 , A61K31/7004 , A61K31/7016 , A61K31/715 , A61K31/716 , A61K31/717 , A61K45/00 , A61P17/00 , A61Q17/00 , A61Q17/04 , A61K9/48
CPC分类号： A61K31/715 , Y10S514/861 , Y10S514/862
摘要： The present invention relates to a composition, and a method for preventing or reducing contact dermatitis. The composition contains a polysaccharide; a low molecular weight, synergistic saccharide; a solvent; and optionally one or more additives. The present invention is further a dermatologically-compatible barrier film for preventing and reducing contact dermatitis which contains a polysaccharide; a low molecular weight, synergistic saccharide; and optionally one or more additives. The dermatologically-compatible barrier film is formed of a composition containing a polysaccharide; a low molecular weight, synergistic saccharide; a solvent; and optional additives. The composition is a skin care product in a form of a lotion, a gel or a cream that is applied to skin of mammals. Once applied, the solvent in the composition evaporates, and thereby leaving behind a dermatologically-compatible barrier film containing polysaccharide and low molecular weight, synergistic saccharide.
摘要翻译：本发明涉及组合物，以及预防或减少接触性皮炎的方法。该组合物含有多糖; 低分子量协同糖; 溶剂; 和任选的一种或多种添加剂。本发明还涉及一种用于预防和减少含有多糖的接触性皮炎的皮肤病学上相容的屏障膜; 低分子量协同糖; 和任选的一种或多种添加剂。皮肤病学相容的阻隔膜由含有多糖的组合物形成; 低分子量协同糖; 溶剂; 和任选的添加剂。该组合物是以乳剂，凝胶或奶油形式施用于哺乳动物皮肤的护肤品。一旦应用，组合物中的溶剂蒸发，从而留下含有多糖和低分子量协同糖的皮肤病学相容的屏障膜。

3. 发明授权

US4875287A Shaving articles lubricious when wet and compositions therefor 失效
标题翻译：剃须物品湿润时润滑，其组成
公开(公告)号：US4875287A
公开(公告)日：1989-10-24
申请号：US931399
申请日：1986-11-14
申请人： Walter S. Creasy , Donald H. Lorenz
发明人： Walter S. Creasy , Donald H. Lorenz
IPC分类号： B26B21/44
CPC分类号： B26B21/443 , B26B21/4012
摘要： The present invention is a shaving article such as a shaving cartridge which includes at least one blade and a blade support having a skin-engaging portion adjacent to a shaving edge of the blade. The skin-engaging portion is provided with a hydrogel comprising a water soluble polymer bound so as to prevent dissolution whereby the coefficient of friction of the skin-engaging portion is reduced in the presence of water.
摘要翻译：本发明是诸如剃须刀片的剃须物品，其包括至少一个刀片和具有与刀片的剃须边缘相邻的皮肤接合部分的刀片支撑件。皮肤接合部分设置有包含水溶性聚合物结合的水凝胶，以防止溶解，从而在水的存在下皮肤接合部分的摩擦系数降低。

4. 发明授权

US4769013A Bio-effecting medical material and device 失效
标题翻译：生物影响医疗材料和装置
公开(公告)号：US4769013A
公开(公告)日：1988-09-06
申请号：US870452
申请日：1986-06-04
申请人： Donald H. Lorenz , Walter S. Creasy
发明人： Donald H. Lorenz , Walter S. Creasy
IPC分类号： A61L15/22 , A61L15/46 , A61L29/06 , A61L29/08 , A61L29/16 , A61M25/00 , C08G18/10 , C08G18/62 , A61K47/00
CPC分类号： C08G18/6283 , A61L15/225 , A61L15/46 , A61L29/06 , A61L29/085 , A61L29/16 , C08G18/10 , A61L2300/106 , A61L2300/202 , A61L2300/404 , A61M2025/0056 , A61M25/0045
摘要： A medical material comprising a polyurethane complexed with polyvinylpyrrolidone and a bio-effecting agent, such as an anti-bacterial agent, complexed with the polyvinylpyrrolidone. The material is used per se as, for example a foam, and as a coating for medical devices such as, for example, catheters and wound drainage tubes.
摘要翻译：包含与聚乙烯吡咯烷酮络合的聚氨酯和与聚乙烯吡咯烷酮络合的生物效应剂如抗菌剂的医用材料。该材料本身用作例如泡沫，以及作为医疗装置例如导管和伤口引流管的涂层。

5. 发明授权

US09474701B2 Antimicrobial soaps containing carvacrol and methods of using same 有权
标题翻译：含有香芹酚的抗微生物肥皂及其使用方法
公开(公告)号：US09474701B2
公开(公告)日：2016-10-25
申请号：US14849393
申请日：2015-09-09
申请人： Hydromer, Inc.
发明人： Manfred F. Dyck , Silke von Dyck , Eric Becktel , Irina Grigorian
IPC分类号： A01N31/14 , A61K8/34 , A01N31/08 , A61Q19/10 , A61K8/92 , A61K8/46 , A01N31/02
CPC分类号： A61K8/347 , A01N31/02 , A01N31/08 , A61K8/34 , A61K8/345 , A61K8/463 , A61K8/922 , A61K2800/5922 , A61Q17/005 , A61Q19/10 , A01N39/00
摘要： The present invention relates to antimicrobial formulations containing carvacrol and at least one of the following 2-phenoxyethanol, caprylyl glycol and hexylene glycol.
摘要翻译：本发明涉及含有香芹酚和以下2-苯氧基乙醇，辛酰二醇和己二醇中的至少一种的抗微生物制剂。

6. 发明授权

US6121375A Gels formed by the interaction of poly(aldehyde) with various substances 有权
公开(公告)号：US6121375A
公开(公告)日：2000-09-19
申请号：US248591
申请日：1999-02-11
申请人： Michael Eknoian
发明人： Michael Eknoian
IPC分类号： A61K9/70 , A01N25/04 , A61F13/00 , A61K8/02 , A61K8/04 , A61K8/33 , A61K8/34 , A61K8/35 , A61K8/36 , A61K8/362 , A61K8/365 , A61K8/49 , A61K8/72 , A61K8/73 , A61K8/81 , A61K8/84 , A61K8/86 , A61K8/88 , A61K31/085 , A61K31/137 , A61K31/165 , A61K31/19 , A61K31/21 , A61K31/245 , A61K31/4178 , A61K31/439 , A61K31/455 , A61K31/48 , A61K31/505 , A61K31/522 , A61K31/545 , A61K31/60 , A61K31/65 , A61K31/702 , A61K31/74 , A61K47/32 , A61L15/16 , A61L15/44 , A61L15/58 , A61L15/60 , A61L15/64 , A61L27/00 , A61P5/00 , A61P9/00 , A61P17/00 , A61P17/02 , A61P21/02 , A61P23/02 , A61P25/02 , A61P25/04 , A61P25/08 , A61P25/20 , A61P25/22 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P35/00 , A61Q3/02 , A61Q19/00 , B29C39/02 , B29C41/00 , B29C65/00 , C08F271/02 , C08L1/02 , C08L29/00 , C08L29/04 , C08L39/00 , C08L39/04 , C08L51/00
CPC分类号： A61K8/042 , A61K8/0212 , A61K8/8129 , A61K8/8158 , A61K8/8176 , A61K8/84 , A61K8/86 , A61K8/88 , A61L15/60 , A61Q19/00 , B29C41/003 , C08F271/02 , C08L39/00 , C08L51/003 , A61K9/7015 , B29C2791/001 , B29C65/00 , B29C66/71
摘要： The present invention, which addresses the needs of the prior art, provides irreversible, hydrophilic gels which can be incorporated into dressing compositions, dermatologically compatible compositions, wound packings, wound dressings, burn dressings, drug delivery dressings, dry films, cosmetic masks and cosmetic wrap dressings. The gels of the invention include a blend of a hydrophilic poly(aldehyde) and a polymer selected from the group consisting of a poly(amide), a poly(amine) and a poly(alcohol).

7. 发明授权

US6110475A Compostion, barrier film, and method for preventing contact dermatitis 失效
标题翻译：组合物，阻隔膜和预防接触性皮炎的方法
公开(公告)号：US6110475A
公开(公告)日：2000-08-29
申请号：US46296
申请日：1998-03-23
申请人： Joan Dalla Riva Toma , Curtis L. Karl
发明人： Joan Dalla Riva Toma , Curtis L. Karl
IPC分类号： A61K8/60 , A01N25/00 , A01N25/34 , A61K6/00 , A61K8/00 , A61K8/20 , A61K8/33 , A61K8/39 , A61K8/40 , A61K8/49 , A61K8/72 , A61K8/73 , A61K31/00 , A61K31/085 , A61K31/70 , A61K31/7004 , A61K31/7016 , A61K31/715 , A61K31/716 , A61K31/717 , A61K45/00 , A61P17/00 , A61Q17/00 , A61Q17/04 , A61K7/00
CPC分类号： A61K31/715 , Y10S514/861 , Y10S514/862
摘要： The present invention relates to a composition, and a method for preventing or reducing contact dermatitis. The composition contains a polysaccharide; a low molecular weight, synergistic saccharide; a solvent; and optionally an additive material.The present invention is further a dermatologically-compatible barrier film for preventing and reducing contact dermatitis which contains a polysaccharide; a low molecular weight, synergistic saccharide; and optionally one or more additives. The dermatologically-compatible barrier film is formed of a composition containing a polysaccharide; a low molecular weight, synergistic saccharide; a solvent; and optionally an additive material. The composition is a skin care product in a form of a lotion, a gel or a cream that is applied to skin of mammals. Once applied, the solvent in the composition evaporates, and thereby leaving behind a dermatologically-compatible barrier film containing a polysaccharide; a low molecular weight, synergistic saccharide; and optionally an additive material.
摘要翻译：本发明涉及组合物，以及预防或减少接触性皮炎的方法。该组合物含有多糖; 低分子量协同糖; 溶剂; 和任选的添加剂材料。本发明还涉及一种用于预防和减少含有多糖的接触性皮炎的皮肤病学上相容的屏障膜; 低分子量协同糖; 和任选的一种或多种添加剂。皮肤病学相容的阻隔膜由含有多糖的组合物形成; 低分子量协同糖; 溶剂; 和任选的添加剂材料。该组合物是以乳剂，凝胶或奶油形式施用于哺乳动物皮肤的护肤品。一旦施用，组合物中的溶剂蒸发，从而留下含有多糖的皮肤病学相容的阻隔膜; 低分子量协同糖; 和任选的添加剂材料。

8. 发明授权

US4550126A Hydrophilic, flexible, open cell polyurethane-poly(N-vinyl lactam) interpolymer foam and dental and biomedical products fabricated therefrom 失效
标题翻译：亲水，柔性，开孔聚氨酯 - 聚（N-乙烯基内酰胺）互聚物泡沫和由其制造的牙科和生物医学产品
公开(公告)号：US4550126A
公开(公告)日：1985-10-29
申请号：US694926
申请日：1985-01-25
申请人： Donald H. Lorenz
发明人： Donald H. Lorenz
IPC分类号： C08G18/00 , A61K6/09 , A61K9/00 , A61K9/70 , A61L15/00 , A61L15/24 , A61L15/42 , C08G18/10 , C08G18/62 , C08J9/02 , C08G18/14
CPC分类号： C08G18/6283 , A61L15/24 , A61L15/425 , C08G18/10
摘要： A hydrophilic, flexible, open cell polyurethane-poly(N-vinyl lactam) interpolymer foam is obtained from the process which comprises reacting under interpolymer and foam-forming conditions (a) a substantially linear isocyanate-capped polyether polyol prepolymer having an average reactive functionality of less that about 2.0 with (b) a poly(N-vinyl lactam) and (c) a foam-forming amount of water in the presence of (d) a cell formation-regulating amount of surface active agent. The foams exhibit unexpectedly higher levels of absorptivity for aqueous fluids compared to those of known crosslinked foams. The foams herein are especially useful for the manufacture of a variety of dental and biomedical products including surgical bandages and dressings, laparotomy sponges, medicament carriers, and the like, where the capability for absorbing body fluids is an important performance criterion.
摘要翻译：从包括在互聚物和泡沫形成条件下反应的方法获得亲水的，柔性的开孔聚氨酯 - 聚（N-乙烯基内酰胺）互聚物泡沫体（a）具有平均反应性官能度的基本上线性的异氰酸酯封端的聚醚多元醇预聚物在（d）表面活性剂的细胞形成调节量的存在下，（b）聚（N-乙烯基内酰胺）和（c）泡沫形成量的水，少于约2.0。与已知的交联泡沫体相比，泡沫体对水性流体的吸收性能出人意料地更高。这里的泡沫特别适用于制造各种牙科和生物医学产品，包括手术绷带和敷料，剖腹术海绵，药物载体等，其中吸收体液的能力是重要的性能标准。

9. 发明授权

US09918991B2 Topical antimicrobial compositions and methods of using same 有权
公开(公告)号：US09918991B2
公开(公告)日：2018-03-20
申请号：US13573544
申请日：2012-09-21
申请人： Hydromer, Inc.
发明人： Irina Grigorian , Manfred F. Dyck , Rainer Gruening
IPC分类号： A01N37/18 , A01N51/00 , A61K31/63 , A01N37/00 , A61K31/19 , A61K31/5415 , A61K31/15 , A61K9/00 , A61K9/08 , A61K31/136
CPC分类号： A61K31/5415 , A61K9/0017 , A61K9/0041 , A61K9/08 , A61K31/136 , A61K31/15
摘要： The invention includes a method of treating a mammal comprising topically applying an aqueous composition to a target site on the mammal, wherein the aqueous composition comprises: active ingredients comprising i) a cosmetic dye selected from a violet, blue or green dye, or combinations thereof, and ii) an enhancing ingredient, wherein the relative weight percentage of the cosmetic dye to the enhancing ingredient is about 1:2 to about 40:1, wherein the cosmetic dye interacts with keratinous material thereby i) substantially staining the target site and ii) inhibiting the active ingredients from significantly leaching from the target site.

10. 发明申请

US20080114096A1 Lubricious biopolymeric network compositions and methods of making same 审中-公开
标题翻译：润滑生物聚合物网络组成及其制备方法
公开(公告)号：US20080114096A1
公开(公告)日：2008-05-15
申请号：US11598223
申请日：2006-11-09
申请人： Xin Qu , Tom Schottman , Rainer Gruening , Paul N. Chen , Joseph Conte , Zheng Wang , Paaquale P. Vicario , Zichun Lu , Karen Meritt , Dave Buongiovanni
发明人： Xin Qu , Tom Schottman , Rainer Gruening , Paul N. Chen , Joseph Conte , Zheng Wang , Paaquale P. Vicario , Zichun Lu , Karen Meritt , Dave Buongiovanni
IPC分类号： A61K8/73 , C08L1/00
CPC分类号： C09D105/08 , A61L17/145 , A61L27/34 , A61L27/50 , A61L29/085 , A61L29/14 , A61L31/10 , A61L31/14 , C08B37/003 , C08B37/0075 , C08J3/246 , C08J2305/08 , C08J2367/04 , C09D105/10
摘要： The invention provides a network composition comprising a plurality of associated saccharide chains wherein a chain comprises at least one saccharide component; and at least one first monomer, at least one second monomer, or combinations of both; wherein the first monomer is linked to the saccharide component by ester linkages; ether linkages; amide linkages; ketone linkages; or combinations thereof; wherein the second monomer is linked to the saccharide component by ester linkages; ether linkages; amide linkages; ketone linkages; urea linkages; carbamate linkages, aluminum oxide linkages; siloxane linkages; or combinations thereof; wherein first monomers are linked to each other by ester linkages; ether linkages; amide linkages; ketone linkages; or combinations thereof; wherein the first monomer is linked to the second monomer by ester linkages; ether linkages; amide linkages; ketone linkages; urea linkages; carbamate linkages; aluminum oxide linkages; siloxane linkages or combinations thereof; wherein the second monomers are linked to each other by ester linkages; ether linkages; amide linkages; ketone linkages; polyvinyl linkages, polyolefin linkages, urea linkages; carbamate linkages, aluminum oxide linkages, siloxane linkages or combinations thereof; and wherein the saccharide components are linked to each other by ester linkages; ether linkages; amide linkages; ketone linkages; or combinations thereof; wherein the network is capable of adhering to a substrate.
摘要翻译：本发明提供一种包含多个相关糖链的网络组合物，其中链包含至少一种糖组分; 和至少一种第一单体，至少一种第二单体或两者的组合; 其中所述第一单体通过酯键与所述糖组分连接; 醚键; 酰胺键; 酮键; 或其组合; 其中所述第二单体通过酯键与所述糖组分连接; 醚键; 酰胺键; 酮键; 尿素键; 氨基甲酸酯键，氧化铝键; 硅氧烷键; 或其组合; 其中第一单体通过酯键相互连接; 醚键; 酰胺键; 酮键; 或其组合; 其中所述第一单体通过酯键与所述第二单体连接; 醚键; 酰胺键; 酮键; 尿素键; 氨基甲酸酯键; 氧化铝键; 硅氧烷键或其组合; 其中所述第二单体通过酯键彼此连接; 醚键; 酰胺键; 酮键; 聚乙烯键，聚烯烃键，脲键; 氨基甲酸酯键，氧化铝键，硅氧烷键或其组合; 并且其中所述糖组分通过酯键彼此连接; 醚键; 酰胺键; 酮键; 或其组合; 其中网络能够粘附到基底。

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