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1. 发明授权

US4487601A Bubble detector circuit with variable reference level 失效
标题翻译：气泡检测器电路具有可变参考电平
公开(公告)号：US4487601A
公开(公告)日：1984-12-11
申请号：US505652
申请日：1983-06-20
申请人： William T. Lindemann
发明人： William T. Lindemann
IPC分类号： A61M1/36 , A61M5/14
CPC分类号： A61M1/3626 , A61M2205/3375 , Y10S128/13
摘要： A bubble detector system is provided which dynamically responds to changes in energy transmission efficiency. The output of a detector is coupled to a dynamic reference level circuit, which develops a reference level that changes slowly in a time-varying manner with changes in the energy level received by the detector. The output of the detector is also coupled to a bubble detector circuit which produces a detection signal that changes rapidly when gas is present between an energy source and the detector. The detection and reference levels are compared to detect the presence of gas in the flow of fluid between the energy source and the detector.
摘要翻译：提供了一种动态响应能量传输效率变化的气泡检测器系统。检测器的输出耦合到动态参考电平电路，其产生随着由检测器接收的能量水平的变化以时变方式缓慢变化的参考电平。检测器的输出还耦合到气泡检测器电路，其产生当在能量源和检测器之间存在气体时快速变化的检测信号。比较检测和参考水平以检测能量源和检测器之间的流体流中气体的存在。

2. 发明授权

US4486189A Dual mode hemodialysis system 失效
标题翻译：双模式血液透析系统
公开(公告)号：US4486189A
公开(公告)日：1984-12-04
申请号：US423376
申请日：1982-09-24
申请人： Vernon H. Troutner , Richard A. Morrow
发明人： Vernon H. Troutner , Richard A. Morrow
IPC分类号： A61M1/30 , A61M1/03
CPC分类号： A61M1/30 , A61M1/302 , A61M1/303 , A61M1/306 , A61M1/308 , Y10S128/03
摘要： A hemodialysis system capable of operation in either a single needle mode or a double needle mode includes an arterial blood pump which is the sole blood pump in the system during the double needle mode. For single needle mode operation a venous blood pump is employed to return blood to the patient. A pump speed control adjusts the speed of the arterial pump in the double needle mode, and the speeds of both blood pumps in the single needle mode. A controller continuously operates the arterial pump in the double needle mode, and alternately activates the two pumps in the single needle mode. A module for modifying a commercially available double needle system for operation in either of the two modes is also described.
摘要翻译：能够以单针模式或双针模式操作的血液透析系统包括在双针模式期间系统中唯一的血液泵的动脉血泵。对于单针模式操作，使用静脉血泵将血液返回给患者。泵速度控制器以双针模式调节动脉泵的速度，并以单针模式调节两个血液泵的速度。控制器以双针模式连续操作动脉泵，并以单针模式交替启动两个泵。还描述了用于修改用于在两种模式中的任一种中操作的市售双针系统的模块。

3. 发明授权

US4476685A Apparatus for heating or cooling fluids 失效
标题翻译：用于加热或冷却流体的装置
公开(公告)号：US4476685A
公开(公告)日：1984-10-16
申请号：US397310
申请日：1982-07-12
申请人： James D. Aid
发明人： James D. Aid
IPC分类号： A61M1/16 , A61M5/44 , F28F3/12 , F25B21/02
CPC分类号： A61M5/44 , A61M1/166 , F28F3/12 , A61M2205/3673
摘要： An apparatus for heating or cooling physiological fluids, such as whole blood and blood plasma, or liquids which are used in the treatment of such physiological fluids, wherein at least one thermoelectric device is used for the heating or cooling.
摘要翻译：一种用于加热或冷却诸如全血和血浆的生理液体或用于治疗这种生理液体的液体的装置，其中至少一个热电装置用于加热或冷却。

4. 发明授权

US4291096A Non-uniform cross-sectional area hollow fibers 失效
标题翻译：不均匀的横截面空心纤维
公开(公告)号：US4291096A
公开(公告)日：1981-09-22
申请号：US19972
申请日：1979-03-12
申请人： John A. Taylor
发明人： John A. Taylor
IPC分类号： B01D67/00 , D01D5/24 , D01D5/253 , D01F2/00 , D02G3/00
CPC分类号： B01D71/10 , B01D69/08 , D01D5/24 , Y10T428/2975 , Y10T428/2976
摘要： Hollow fibers, particularly useful as semipermeable membranes in separatory devices such as blood dialyzers, having a non-uniform cross-sectional area along the length thereof. The fibers have recurring points of maximum outside diameter and minimum outside diameter and such points may recur on a regular basis or at random. Fiber wall thicknesses may be substantially uniform or non-uniform. Methods and apparatus for making the fibers are disclosed.
摘要翻译：中空纤维，特别适用于分离装置如血液透析器中的半透膜，沿其长度具有不均匀的横截面积。纤维具有最大外径和最小外径的重复点，并且这些点可以定期或随机地再现。纤维壁厚可以是基本均匀的或不均匀的。公开了制造纤维的方法和设备。

5. 发明授权

US3985655A Dialyzer coil with porous support for membrane 失效
标题翻译：带多孔支架的透析器盘管
公开(公告)号：US3985655A
公开(公告)日：1976-10-12
申请号：US470601
申请日：1974-05-16
申请人： Frederick W. Miller, III
发明人： Frederick W. Miller, III
IPC分类号： A61M20060101 , A61M1/24 , B01D63/10 , B01D31/00
CPC分类号： B01D61/28 , B01D63/10
摘要： An extracorporeal, disposable, low-prime dialyzer coil for use in a variety of artificial kidney systems which includes a length of porous material supporting the tube of membrane material in a generally flattened and rolled up configuration. The length of porous material has an average thickness along its edge portions which is no greater than the average thickness along its mid-portion, and has an embossed configuration on one side while the other side is relatively smooth. The porous material is rigidized thermoplastic or thermosetting material, composed for instance of sintered granules or foamed open cells, with a majority of the pores or openings communicating with the surface to insure full dialysate flow against the membrane material. The porous support material is useful in a wide variety of coil designs, including coils adapted for operation with recirculating artificial kidney systems, with non-recirculating systems, or with systems combining recirculation with fresh dialysate addition.
摘要翻译：一种体外，一次性，低质量的透析器线圈，用于各种人造肾脏系统，其包括一长度的多孔材料，其以大致扁平和卷起的构型支撑膜材料管。多孔材料的长度沿其边缘部分具有不大于其中间部分的平均厚度的平均厚度，并且在一侧具有压花构造，而另一侧相对平滑。多孔材料是刚性化的热塑性或热固性材料，其由例如烧结颗粒或泡沫开孔组成，其中大部分孔或开口与表面连通以确保完全透析液流过膜材料。多孔支撑材料可用于各种线圈设计，包括适于与再循环人造肾系统操作的线圈，具有非再循环系统，或与再循环与新鲜透析液添加组合的系统。

6. 发明授权

US4573961A Electronic control methods for puvapheresis apparatus 失效
标题翻译：血液分离装置的电子控制方法
公开(公告)号：US4573961A
公开(公告)日：1986-03-04
申请号：US665831
申请日：1984-10-29
申请人： Martin J. King
发明人： Martin J. King
IPC分类号： A61M1/36 , A61M37/00
CPC分类号： A61M1/3681 , A61M1/3616 , A61M1/3683 , A61M1/3693
摘要： Methods are provided for ensuring the safety of a patient undergoing extracorporeal treatment by irradiation of a photoactivatable reagent in contact with the patient's blood including simultaneous digital and analog monitoring of temperature, voltage and current sensor signals. Also provided is a control system for controlling and regulating the various components of the photophoresis patient treatment system.
摘要翻译：提供了通过照射与患者血液接触的可光活化试剂来确保接受体外治疗的患者的安全性的方法，包括对温度，电压和电流传感器信号的同时数字和模拟监测。还提供了用于控制和调节光泳患者治疗系统的各种组分的控制系统。

7. 发明授权

US4496458A Dialysis apparatus and technique 失效
标题翻译：透析仪和技术
公开(公告)号：US4496458A
公开(公告)日：1985-01-29
申请号：US55881
申请日：1979-07-09
申请人： Kyu H. Lee
发明人： Kyu H. Lee
IPC分类号： A61M1/16 , B01D31/00
CPC分类号： A61M1/16
摘要： Dialysis apparatus is arranged to enable convenient measuring of ultrafiltration rate from liquid, such as blood, that is to be dialyzed. Dialyzer can have, downstream of a dialysis chamber, a dialyzate passageway through which the ultrafiltration flow rate can be readily measured as by introducing a gas bubble into the dialyzate and timing its movement through the passageway. An air-injection attachment can be fitted to the dialyzer or to a dialyzate supply system, to inject the gas bubble for such measurement. Bubble injection can also be effected in a flow rate measuring passageway downstream of the dialyzer. Flow rates of dialyzate into and out of dialyzer can be compared to show ultrafiltration while dialyzing. Dialyzer can also have end caps with thickned closure walls for better ultrasonic welding to the dialyzer body, and the caps can have vents that simplify testing of the seals between the caps and the dialysis membrane body.
摘要翻译：透析装置被设置为能够方便地测量要透析的液体（例如血液）的超滤速率。透析器可以在透析室的下游具有透析液通道，通过该透析液通道可以容易地测量超滤流速，方法是通过将气泡引入透析液并使其运动通过通道。可以将空气注射附件安装到透析器或透析液供应系统，以便将气泡注入用于这种测量。也可以在透析器下游的流量测量通道中进行气泡注射。透析液进出透析液的流量可以比较，透析时显示超滤。透析器还可以具有带盖的封闭壁的端盖，用于更好地超声波焊接到透析器本体，并且帽可以具有简化测试帽和透析膜体之间的密封的通风口。

8. 发明授权

US4428403A Conduit having spirally wound monofilament material 失效
标题翻译：管道具有螺旋缠绕的单丝材料
公开(公告)号：US4428403A
公开(公告)日：1984-01-31
申请号：US385178
申请日：1982-06-04
申请人： Kyu H. Lee , Christopher H. Porter
发明人： Kyu H. Lee , Christopher H. Porter
IPC分类号： A61M1/18 , A61M5/44 , F16L11/12
CPC分类号： A61M5/44 , A61M2205/366 , Y10S138/06
摘要： Device useful as a heat exchanger for blood or as an apparatus in which blood may be treated or reacted with selected reactants. Device comprises hollow tubing which has plastic monofilament placed in a generally spiral configuration around its outer surface, said monofilament being in the form of continuous or discontinuous projections or ridges. Strands of wire may be substituted for the plastic monofilament. Hollow tubing having such plastic monofilament or strands of wire is also included.
摘要翻译：可用作血液的热交换器的装置，或用于血液可以与所选反应物反应的装置。装置包括中空管，其具有围绕其外表面置于大致螺旋形构型的塑料单丝，所述单丝为连续或不连续的突起或脊的形式。线的绞线可以代替塑料单丝。还包括具有这种塑料单丝或线股的中空管。

9. 发明授权

US4184962A Totally wrapped coil permeation device and artificial kidney 失效
标题翻译：完全包裹线圈渗透装置和人造肾
公开(公告)号：US4184962A
公开(公告)日：1980-01-22
申请号：US917083
申请日：1978-06-19
申请人： Rolf A. Oscarsson , Albert E. Moore
发明人： Rolf A. Oscarsson , Albert E. Moore
IPC分类号： A61M1/24 , B01D63/10 , B01D31/00
CPC分类号： B01D61/28 , B01D63/10 , B01D2313/02
摘要： A wrapped coil-type permeation device wherein the support material has integrally formed therein thickened side strips and end areas suitable for creating a winding core upon which membrane and support material windings are layered and/or an outer covering or casing for the wound coil device. The support material end areas include interlocking portions and fluid ports.
摘要翻译：一种卷绕的线圈型渗透装置，其中支撑材料一体地形成有加厚的侧条和适合于产生缠绕芯的端部区域，膜和支撑材料绕组在该卷芯上分层和/或用于缠绕线圈装置的外覆盖物或外壳。支撑材料端部区域包括互锁部分和流体端口。

10. 发明授权

US4028252A Accordion fold flat plate dialyzer 失效
标题翻译：手风琴折叠平板透析器
公开(公告)号：US4028252A
公开(公告)日：1977-06-07
申请号：US583648
申请日：1975-06-04
申请人： Livingston B. Morris
发明人： Livingston B. Morris
IPC分类号： A61M20060101 , A61M1/22 , B01D20060101 , B01D61/24 , B01D61/32 , B01D63/14 , B65H45/12 , G01N13/04 , B01D31/00
CPC分类号： B01D61/28 , B01D63/14 , B01D2313/04 , B01D2313/14
摘要： A support material is fed through mating elements which emboss transverse score lines thereon to form an accordion fold in the material. A single thickness of the folded support material is then interleaved with a permeable membrane and sealed in a housing to form a compact inexpensive flat plate dialyzer. Longitudinal channels are formed in the support material which materially improve distribution of fluids within the dialyzer.
摘要翻译：支撑材料通过配合元件进给，该配合元件在其上压花横向刻痕线以在材料中形成折叠折叠。然后将折叠的支撑材料的单一厚度与可渗透膜交错并密封在壳体中以形成紧凑廉价的平板透析器。在支撑材料中形成纵向通道，其实质上改善透析器内流体的分布。

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