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1. 发明授权

US4053418A Embossed membrane support 失效
标题翻译：胶囊支撑
公开(公告)号：US4053418A
公开(公告)日：1977-10-11
申请号：US620612
申请日：1975-10-08
申请人： Ferris E. Newman
发明人： Ferris E. Newman
IPC分类号： A61B20060101 , A61M20060101 , A61M1/24 , B01D20060101 , B01D63/10 , B01D31/00
CPC分类号： B01D61/28 , B01D63/10 , B01D2313/146
摘要： An elongated, flexible and embossed support member is disclosed herein for use in a coil-type artificial kidney dialyzer to support an elongated, flattened and tubularly shaped semipermeable membrane. The membrane is of cellophane or a cellulose derivative and has the characteristic of stretching further in the transverse direction than in the longitudinal direction. The support member includes an imperforate fluid-impermeable web having angle ribs on one side and skip ribs on the other side for positioning and supporting the membrane within the dialyzer. The angle ribs extend angularly from one longitudinal edge of the member to the other longitudinal edge and the skip ribs are arranged in longitudinal rows, with each row including a plurality of intermittently spaced skip ribs. The skip ribs are higher than the angle ribs and both sets of ribs are of a height effective to prevent the membrane from contacting the web.

2. 发明授权

US4022692A Non-woven support screen for mass transfer devices 失效
标题翻译：用于传质装置的无纺布支撑屏
公开(公告)号：US4022692A
公开(公告)日：1977-05-10
申请号：US601193
申请日：1975-08-01
申请人： Howard A. Janneck
发明人： Howard A. Janneck
IPC分类号： D04H3/04 , A61M20060101 , A61M1/24 , B01D20060101 , B01D61/08 , B01D61/18 , B01D63/10 , D04H20060101 , D04H3/14 , B01D31/00
CPC分类号： B01D63/10 , B01D65/02 , B01D2313/086 , B01D2313/143 , B01D2321/2091
摘要： An improved non-woven support screen for mass transfer devices including a first set of parallel spaced longitudinally extending filaments having a predetermined thickness or diameter and a second set of parallel spaced filaments obliquely arranged relative to the first set of filaments and having a predetermined thickness or diameter approximately 1/2 that of the first set of filaments to provide improved control of membrane distention for minimizing the masking of the membrane surface by preventing excessive distention in one plane, to reduce the volume of body fluid layer in the membrane (low prime), and provide improved mass transfer efficiency while maintaining gentle mixing of the body fluid. Moreover, the velocity gradient of the exchange fluid is enhanced by the limited space provided for the exchange fluid channels to significantly improve the scrubbing action of the exchange fluid on the membrane surface. Advantageously, the larger diameter of the filaments of the first set provides low operating fluid pressure within the membrane channels by allowing selective distention of the membrane.
摘要翻译：一种用于质量传递装置的改进的无纺支撑筛，其包括具有预定厚度或直径的第一组平行间隔开的纵向延伸的长丝和相对于第一组长丝倾斜布置并具有预定厚度的第二组平行隔开的长丝，直径约为第一组长丝的1/2，以提供改进的膜膨胀控制，以通过防止一个平面中的过度膨胀来最小化膜表面的掩蔽，从而减小膜中的体液层的体积（低质量）并且在保持体液的温和混合的同时提供改进的传质效率。此外，通过为交换流体通道提供的有限的空间来增强交换流体的速度梯度，以显着地改善膜表面上的交换流体的洗涤作用。有利地，通过允许膜的选择性扩张，第一组的细丝的较大直径在膜通道内提供低的工作流体压力。

3. 发明授权

US3985655A Dialyzer coil with porous support for membrane 失效
标题翻译：带多孔支架的透析器盘管
公开(公告)号：US3985655A
公开(公告)日：1976-10-12
申请号：US470601
申请日：1974-05-16
申请人： Frederick W. Miller, III
发明人： Frederick W. Miller, III
IPC分类号： A61M20060101 , A61M1/24 , B01D63/10 , B01D31/00
CPC分类号： B01D61/28 , B01D63/10
摘要： An extracorporeal, disposable, low-prime dialyzer coil for use in a variety of artificial kidney systems which includes a length of porous material supporting the tube of membrane material in a generally flattened and rolled up configuration. The length of porous material has an average thickness along its edge portions which is no greater than the average thickness along its mid-portion, and has an embossed configuration on one side while the other side is relatively smooth. The porous material is rigidized thermoplastic or thermosetting material, composed for instance of sintered granules or foamed open cells, with a majority of the pores or openings communicating with the surface to insure full dialysate flow against the membrane material. The porous support material is useful in a wide variety of coil designs, including coils adapted for operation with recirculating artificial kidney systems, with non-recirculating systems, or with systems combining recirculation with fresh dialysate addition.
摘要翻译：一种体外，一次性，低质量的透析器线圈，用于各种人造肾脏系统，其包括一长度的多孔材料，其以大致扁平和卷起的构型支撑膜材料管。多孔材料的长度沿其边缘部分具有不大于其中间部分的平均厚度的平均厚度，并且在一侧具有压花构造，而另一侧相对平滑。多孔材料是刚性化的热塑性或热固性材料，其由例如烧结颗粒或泡沫开孔组成，其中大部分孔或开口与表面连通以确保完全透析液流过膜材料。多孔支撑材料可用于各种线圈设计，包括适于与再循环人造肾系统操作的线圈，具有非再循环系统，或与再循环与新鲜透析液添加组合的系统。

4. 发明授权

US3892533A Oxygenator gas distribution header 失效
标题翻译：氧气机气体分配头
公开(公告)号：US3892533A
公开(公告)日：1975-07-01
申请号：US33767773
申请日：1973-03-02
申请人： SCI MED
发明人： FREEDMAN FRANK B , UFFORD KEITH A
IPC分类号： A61M1/24 , A61M16/00 , A61M1/03
CPC分类号： B01D63/10 , A61M1/1698 , Y10S128/03
摘要： A spool wound membrane oxygenator or artificial lung. The oxygenator includes a membrane envelope assembly wound around a core of a plastic spool with the principle of gas diffusion through a membrane being utilized. Each disk shaped end plate of the spool is provided with aperture means for blood carrying tubing and aperture means for gas carrying tubing. The oxygen and blood inlet and outlet means are so disposed as to provide a substantially countercurrent flow pattern of oxygen and blood through the mass transfer section of the oxygenator.
摘要翻译：线轴缠绕膜充氧器或人造肺。氧合器包括缠绕在塑料阀芯的芯上的膜包络组件，其原理是通过所使用的膜的气体扩散。线轴的每个盘形端板设置有用于血液输送管道的孔口装置和用于气体输送管道的孔口装置。氧气和血液入口和出口装置被设置成通过氧合器的传质部分提供氧气和血液的基本上逆流的流动模式。

5. 发明授权

US3853769A Rigid casing for dialyzer coil 失效
标题翻译： DIALYZER线圈的刚性壳
公开(公告)号：US3853769A
公开(公告)日：1974-12-10
申请号：US34801073
申请日：1973-04-05
申请人： EXTRACORPOREAL MED SPEC
发明人： MILLER F
IPC分类号： A61M20060101 , A61M1/24 , B01D63/10 , B01D31/00
CPC分类号： B01D63/10 , B01D61/28 , B01D2313/02
摘要： A rigid, clear, transparent styrene casing for a dialyzer coil of the type useful in artificial kidney machines wherein the casing consists of an upper end cap and a lower end cap, each being generally cup-shaped and proportioned for mating engagement with each other at their rim portions and tapering slightly inwardly from their rim portions to their base portions. There is also provided an optional cylindrical extension member which may be positioned between the upper and lower end caps to provide an elongated casing for an elongated dialyzer coil. In either arrangement, the base portion of the lower end cap has an outwardly extending central flange adapted for engagement with a dialysis inflow opening of an artificial kidney machine, and the base portion of the upper end cap has a large central aperture and a plurality of smaller dialysis outflow apertures spaced in a circle around the large central aperture.
摘要翻译：一种用于人造肾脏机器类型的透析器线圈的刚性，透明，透明的苯乙烯壳体，其中壳体由上端盖和下端盖组成，每个帽通常为杯形并且成比例地用于彼此配合接合它们的边缘部分并且从它们的边缘部分向其基部略微向内变细。还提供了可选的圆柱形延伸构件，其可以位于上端盖和下端盖之间，以提供用于细长透析器线圈的细长壳体。在任一方式中，下端盖的基部具有适于与人造肾机的透析流入口接合的向外延伸的中心凸缘，并且上端盖的基部具有大的中心孔和多个较小的透析流出孔围绕大的中心孔间隔开一圈。

6. 发明授权

US3712475A Positive pressure lid for dialyzer apparatus 失效
标题翻译： DIALYZER设备的正压力指示灯
公开(公告)号：US3712475A
公开(公告)日：1973-01-23
申请号：US3712475D
申请日：1970-08-31
申请人： BAXTER LABORATORIES INC
发明人： MARTINEZ F
IPC分类号： A61M1/16 , A61M1/24 , B01D63/10 , B01D31/00
CPC分类号： B01D63/10 , A61M1/16 , A61M2205/3331 , B01D61/28 , B01D61/32 , B01D2313/18 , B01D2313/21
摘要： A cover for sealingly closing the dialysate chamber of an extracorporeal kidney apparatus and providing a flow duct for passing dialyzing fluid from the chamber. A valve in said flow duct to adjust the flow (volume/time) and vary the pressure within the dialyzing fluid compartment.
摘要翻译：一种用于密封关闭体外肾脏装置的透析液室并提供用于使来自腔室的透析液体流过的流动管道的盖子。所述流道中的阀，用于调节流量（体积/时间）并改变透析流体隔室内的压力。

7. 发明授权

US3712474A Artifical kidney apparatus 失效
标题翻译：手工设备
公开(公告)号：US3712474A
公开(公告)日：1973-01-23
申请号：US3712474D
申请日：1970-04-08
申请人： BAXTER LABORATORIES INC
发明人： MARTINEZ F
IPC分类号： A61M1/24 , B01D63/10 , F16L5/00 , F16L5/02 , F16L35/00 , F16L47/06 , B01D31/00
CPC分类号： B01D61/28 , B01D63/10 , B01D2313/00 , F16L5/10 , F16L47/065
摘要： An artificial kidney apparatus providing a blood compartment which is entirely self-contained within its own structure. The apparatus further provides, in the self-contained assembly, structure to vary the positive pressure within a dialysate chamber and the pressure gradient across the diffusion membrane. Improved connector units provide uniform blood distribution into the diffusion membrane.
摘要翻译：一种人造肾脏装置，其提供在其自身结构内完全独立的血液隔室。该装置在独立组件中进一步提供了改变透析液室内的正压力和横跨扩散膜的压力梯度的结构。改进的连接器单元提供均匀的血液分布到扩散膜。

8. 发明授权

US3687293A Therapeutic device 失效
标题翻译：治疗装置
公开(公告)号：US3687293A
公开(公告)日：1972-08-29
申请号：US3687293D
申请日：1970-10-30
申请人： AVON RUBBER CO LTD
发明人： CARTER DOUGLAS VAUGHAN
IPC分类号： A61F20060101 , A61M20060101 , A61M1/00 , A61M1/24 , B01D63/10 , B29D7/00 , B01D31/00
CPC分类号： B01D63/10 , B01D61/28 , B01D2313/146
摘要： A haemodialysis unit suitable for use in an artificial kidney machine has a blood conduit which has a wall of semi-permeable material on each of closely spaced opposite sides and plastics material sheet outside and on each side of the conduit. The sheet on each side provides, with a wall of semi-permeable material on that side, walls of a passage for dialysing liquid. On each side of the conduit the sheet has parallel liquid flow-directing ribs which are directed towards and into contact with the wall of semi-permeable material. The ribs on one side of the conduit are at an angle to the ribs on the opposite side. The blood conduit may be in the form of a tube or tubes of semi-permeable material and this may be coiled together with a length of a novel form of plastics material sheet which has ribs on both sides, the ribs on one side of the sheet being at an angle to the ribs on the other side.
摘要翻译：适合用于人造肾脏机器的血液透析装置具有血管，其导管在密封间隔开的相对侧和在导管的每一侧上的塑料材料片上具有半透性材料壁。每侧的片材在该侧提供半透水材料的壁，用于透析液体的通道的壁。在管道的每一侧上，片材具有平行的液体流动导向肋，其朝向半透性材料的壁并且与其接触。导管一侧的肋与相对侧的肋成一角度。血液导管可以是半导体材料的管或管的形式，并且其可以卷绕在一起，其长度为两面具有肋的新型塑料材料片，片的一侧上的肋与另一侧的肋骨成一角度。

9. 发明授权

US3505686A Device for effecting blood interchange functions 失效
标题翻译：用于影响血液交换功能的装置
公开(公告)号：US3505686A
公开(公告)日：1970-04-14
申请号：US3505686D
申请日：1965-03-08
申请人： BODELL BRUCE R
发明人： BODELL BRUCE R
IPC分类号： A61M1/16 , A61M1/18 , A61M1/24 , B01D63/02 , B01D63/06 , A61F1/00 , A61M1/03 , B07B1/28
CPC分类号： B01D63/02 , A61M1/16 , A61M1/1678 , A61M1/1698 , B01D63/068

10. 发明授权

US5167817A Transfer membrane apparatus 失效
标题翻译：转移膜装置
公开(公告)号：US5167817A
公开(公告)日：1992-12-01
申请号：US474064
申请日：1990-05-29
申请人： Brian J. Bellhouse
发明人： Brian J. Bellhouse
IPC分类号： A61M1/22 , A61M1/24 , B01D61/24 , B01D63/00 , B01D63/08 , B01D65/08
CPC分类号： B01D63/082 , B01D65/08 , B01D2321/2066
摘要： A transfer membrane assembly in which one fluid is passed with a pulsatile flow through a first conduit between two transfer membranes which are provided with a close packed array of dimples so that vortex mixing occurs. Second conduits are formed on the other side of each membrane between that membrane and an adjacent profiled plate. Each dimple partially nests in a depression in the respective plate, the depressions being connected in rows by grooves. The maximum diameter and depth of each dimple is less than the corresponding dimensions of the respective depression.
摘要翻译： PCT No.PCT / GB88 / 00946 Sec。 371日期1990年5月29日第 102（e）日期1990年5月29日PCT提交1988年11月1日PCT公布。出版物WO89 / 04197 日期1989年5月18日。一种转移膜组件，其中一个流体通过脉动流通过两个转移膜之间的第一导管，所述第二导管设置有紧密堆积的凹坑阵列，从而发生涡流混合。在膜和相邻异型板之间的每个膜的另一侧上形成第二导管。每个凹坑部分地嵌在相应板的凹陷中，凹陷通过凹槽被排成一行。每个凹坑的最大直径和深度小于相应凹部的相应尺寸。

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