会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 2. 发明授权
    • Sample preparation chamber with mixer/grinder and sample aliquot
isolation
    • 样品制备室,配有搅拌器/研磨机和样品等分试样
    • US4792434A
    • 1988-12-20
    • US942198
    • 1986-12-16
    • Andre MetzgerPeter GrimmAndre J. NohlVance J. Nau
    • Andre MetzgerPeter GrimmAndre J. NohlVance J. Nau
    • B01F7/00B01F13/00B01F15/00G01N1/28B01F7/22B01L3/00B28C5/08
    • G01N1/286B01F13/002B01F15/00538B01F15/00487B01F7/00
    • There is disclosed a sample preparation chamber for a system for preparing samples of various compositions for assay by liquid chromatography. The sample preparation chamber is a container having a threaded cap and a threaded, lightweight, translucent plastic cup. A stirred/grinder shaft driven by a motor and connected to a propeller/grinder passes through the cap. The cap has a sloped bottom with a sump region, and a fill/empty pipe passes through the cap and has its outlet at or near the sump. A nozzle fill pipe arrangement allows the walls to be washed down as liquid is pumped into the cup. A second fill pipe with its outlet spaced up from the bottom of the cup is also used, and a sample metering valve having an inlet in said cup is present. The sample metering valve is used to isolate a known volume of the sample from the rest of the sample for release back into the cup after the remaining sample has been pumped to waste for purposes of diluting the known volume of sample to a known concentration.
    • 公开了用于制备用于通过液相色谱法测定的各种组合物的样品的系统的样品制备室。 样品制备室是具有螺纹盖和螺纹,重量轻的半透明塑料杯的容器。 由电机驱动并连接到螺旋桨/研磨机的搅拌/研磨机轴穿过盖子。 盖子有一个倾斜的底部,带有一个集水区,一个填充/空的管道穿过盖子,并在其底部或附近有出口。 喷嘴填充管布置允许当液体被泵入杯中时壁被冲洗掉。 还使用具有与杯的底部间隔开的出口的第二填充管,并且存在具有在所述杯中的入口的样品计量阀。 样品计量阀用于将已知体积的样品与样品的其余部分分离,以将剩余的样品泵送到废物后释放回杯中,以将已知体积的样品稀释至已知浓度。
    • 6. 发明授权
    • Aromatic acids
    • 芳香酸
    • US5382659A
    • 1995-01-17
    • US255298
    • 1994-06-07
    • Jui Y. Chang
    • Jui Y. Chang
    • C07C309/46C07C309/51C07C331/28G01N33/68C09B29/085
    • G01N33/6818C07C309/46C07C309/51C07C331/28
    • The invention relates to novel aromatic acids, especially to compounds of formula ##STR1## wherein R.sub.1 is lower alkyl, R.sub.2 is lower alkyl, R.sub.3 is hydrogen, carboxy or sulfo, R.sub.4 is carboxy or sulfo, G is an unsubstituted or substituted 1,4-phenylene group or an unsubstituted or substituted 1,4-naphthylene group, and wherein either R.sub.5 and R.sub.6 together are an additional bond and L is an oxygen or sulfur atom or wherein R.sub.5 is hydrogen, R.sub.6 is halomethyl and L is an oxygen atom, and salts thereof, to the use of compounds I and their salts, to a process for the preparation of compounds I and their salts, to starting materials used in that preparation process, and salts thereof, to a process for the preparation of those starting materials and their salts, to a device in which the compounds I and their salts are used, and to a process in which that device is used. The compounds of formula I can be used as adjuncts in the investigation of proteins and can be prepared in a manner known per se.
    • 本发明涉及新的芳族酸,特别是涉及其中R 1为低级烷基,R 2为低级烷基,R 3为氢,羧基或磺基,R 4为羧基或磺基的式(I)化合物,G为未取代或取代的 1,4-亚苯基或未取代或取代的1,4-亚萘基,其中R 5和R 6一起是另外的键,L是氧或硫原子,或其中R 5是氢,R 6是卤代甲基,L是 氧原子及其盐,使用化合物I及其盐,将化合物I及其盐的制备方法用于该制备方法中使用的原料及其盐,制备方法 这些原料及其盐与使用化合物I及其盐的装置以及使用该装置的方法。 式I化合物可用作蛋白质研究中的辅助物质,并且可以以本身已知的方式制备。
    • 8. 发明授权
    • Aminooxy piperidines as ornithine decarboxylase inhibitors
    • 氨基氧哌啶类作为鸟氨酸脱羧酶抑制剂
    • US5322852A
    • 1994-06-21
    • US16407
    • 1993-02-11
    • Jorg FreiJaroslav Stanek
    • Jorg FreiJaroslav Stanek
    • A61K31/445A61K31/4458A61P33/02A61P35/00A61P43/00C07D211/22C07D211/42C07D211/46C07D211/26C07D211/40
    • C07D211/22C07D211/46
    • The invention relates to compounds of formula I ##STR1## wherein either R.sub.1 is a radical of formula Ia,--(CH.sub.2).sub.n --O--NH.sub.2 (Ia)in which n is 0 or 1, is hydrogen and R.sub.2 is a radical of formula Ib,--(CH.sub.2).sub.p --O--NH.sub.2 (Ib)in which p is 1 or 2, and wherein R is C.sub.1 -C.sub.2 alkyl which is attached to one carbon atom of the central piperidine ring system, but not to the same carbon atom as R.sub.1 of formula Ia or as R.sub.2 of formula Ib; and m is 1 or 2, and salts thereof. The invention further relates to the preparation of these compounds, to intermediates obtained during their synthesis, to pharmaceutical compositions which contain them, and to the use of said compounds for the therapeutic treatment of the human or animal body and for the preparation of pharmaceutical compositions.The compounds of formula I are inhibitors of ornithin decarboxylase.
    • 本发明涉及式I化合物其中R 1为式Ia基团, - (CH 2)n O-NH 2(Ia),其中n为0或1,为氢,R 2为 式Ib, - (CH 2)p O-NH 2(Ib),其中p是1或2,并且其中R是连接到中心哌啶环体系的一个碳原子但不与碳原子相同的C 1 -C 2烷基, 式Ia的R 1或式Ib的R 2; 和m为1或2,及其盐。 本发明还涉及这些化合物,其在合成期间获得的中间体,其含有它们的药物组合物的制备,以及所述化合物用于人或动物体的治疗和用于制备药物组合物的用途。 式I化合物是鸟氨酸脱羧酶的抑制剂。