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1. 发明授权

US4618674A Red-1-(cyanophenylazo- or cyano, halophenylazo)-2-amino-8-hydroxynaphthalene-6 sulfonic acid dyestuffs 失效
标题翻译：红-1-（氰基苯基偶氮或氰基，卤苯基偶氮）-2-氨基-8-羟基萘-6-磺酸染料
公开(公告)号：US4618674A
公开(公告)日：1986-10-21
申请号：US567295
申请日：1983-12-30
申请人： Kurt A. Dellian
发明人： Kurt A. Dellian
IPC分类号： C09B29/16 , C09B29/30 , C09B67/22 , D06P3/06 , D06P3/24 , C09B29/01 , D06P1/39
CPC分类号： D06P3/06 , C09B29/30 , C09B67/0046 , Y10S534/01
摘要： Red monoazo dyestuffs from diazotized 1-aminobenzonitrile or 1-amino-4-, 5- or 6-halo-benzonitrile and 2-amino-8-hydroxynaphthalene-6-sulfonic acid. These dyes are particularly distinguished by their good migration and leveling properties and excellent fastness to light. Said dyestuffs are moreover suitable for obtaining very even combination dyeings together with known blue, yellow and orange acid dyestuffs. These dyestuffs are particularly suited for the dyeing of carpeting, upholstery fabrics and drapery materials.
摘要翻译：来自重氮化的1-氨基苄腈或1-氨基-4-，5-或6-卤代 - 苄腈和2-氨基-8-羟基萘-6-磺酸的红色单偶氮染料。这些染料特别通过其良好的迁移和流平性能以及优异的耐光牢度来区分。所述染料还适用于与已知的蓝色，黄色和橙色酸性染料一起获得非常均匀的组合染色。这些染料特别适用于地毯，室内装潢织物和帷幔材料的染色。

2. 发明授权

US4792434A Sample preparation chamber with mixer/grinder and sample aliquot isolation 失效
标题翻译：样品制备室，配有搅拌器/研磨机和样品等分试样
公开(公告)号：US4792434A
公开(公告)日：1988-12-20
申请号：US942198
申请日：1986-12-16
申请人： Andre Metzger , Peter Grimm , Andre J. Nohl , Vance J. Nau
发明人： Andre Metzger , Peter Grimm , Andre J. Nohl , Vance J. Nau
IPC分类号： B01F7/00 , B01F13/00 , B01F15/00 , G01N1/28 , B01F7/22 , B01L3/00 , B28C5/08
CPC分类号： G01N1/286 , B01F13/002 , B01F15/00538 , B01F15/00487 , B01F7/00
摘要： There is disclosed a sample preparation chamber for a system for preparing samples of various compositions for assay by liquid chromatography. The sample preparation chamber is a container having a threaded cap and a threaded, lightweight, translucent plastic cup. A stirred/grinder shaft driven by a motor and connected to a propeller/grinder passes through the cap. The cap has a sloped bottom with a sump region, and a fill/empty pipe passes through the cap and has its outlet at or near the sump. A nozzle fill pipe arrangement allows the walls to be washed down as liquid is pumped into the cup. A second fill pipe with its outlet spaced up from the bottom of the cup is also used, and a sample metering valve having an inlet in said cup is present. The sample metering valve is used to isolate a known volume of the sample from the rest of the sample for release back into the cup after the remaining sample has been pumped to waste for purposes of diluting the known volume of sample to a known concentration.
摘要翻译：公开了用于制备用于通过液相色谱法测定的各种组合物的样品的系统的样品制备室。样品制备室是具有螺纹盖和螺纹，重量轻的半透明塑料杯的容器。由电机驱动并连接到螺旋桨/研磨机的搅拌/研磨机轴穿过盖子。盖子有一个倾斜的底部，带有一个集水区，一个填充/空的管道穿过盖子，并在其底部或附近有出口。喷嘴填充管布置允许当液体被泵入杯中时壁被冲洗掉。还使用具有与杯的底部间隔开的出口的第二填充管，并且存在具有在所述杯中的入口的样品计量阀。样品计量阀用于将已知体积的样品与样品的其余部分分离，以将剩余的样品泵送到废物后释放回杯中，以将已知体积的样品稀释至已知浓度。

3. 发明授权

US4452602A Process for dyeing leather with mixtures of dyes 失效
标题翻译：用染料混合染色皮革的方法
公开(公告)号：US4452602A
公开(公告)日：1984-06-05
申请号：US360025
申请日：1982-03-19
申请人： Alois Puntener , Josef Koller , Fabio Beffa
发明人： Alois Puntener , Josef Koller , Fabio Beffa
IPC分类号： C09B45/00 , C09B55/00 , D06P3/30 , D06P3/32 , D06P1/10
CPC分类号： C09B45/00 , C09B55/001 , D06P3/30 , D06P3/32 , Y10S534/01
摘要： A mixture of at least three selected 1:2 chromium or 1:2 cobalt complex dyes of different colors and belonging to the azo or azomethine series is used for dyeing leather and furs. The mixtures of dyes make it possible for the first time to dye leather by the trichromatic process.
摘要翻译：使用属于偶氮或偶氮甲碱系列的不同颜色的至少三种选择的1:2铬或1:2钴络合物染料的混合物用于染色皮革和毛皮。染料的混合物使得第一次通过三色过程染色皮革成为可能。

4. 发明授权

US5481039A Compositions comprising 2,2',2"-nitrilotriethanol cyclometalates 失效
标题翻译：包含2,2'，2“ - 次氮基三乙醇环金属盐的组合物
公开(公告)号：US5481039A
公开(公告)日：1996-01-02
申请号：US327245
申请日：1994-10-21
申请人： Hermann O. Wirth , Hans-Helmut Friedrich
发明人： Hermann O. Wirth , Hans-Helmut Friedrich
IPC分类号： C07F5/02 , C07F5/04 , C07F5/06 , C07F7/00 , C07F9/00 , C07F9/90 , C07F9/94 , C07F11/00 , C07F15/02 , C07F19/00 , C08K5/00 , C08K5/34 , C08K5/37 , C08K5/55 , C08K5/56 , C08K5/59 , C09K15/30 , C10L1/10 , C10L1/22 , C10L1/30 , C10L10/00 , C10L10/08 , C10M139/00 , C10M159/18 , C10N10/02 , C10N10/04 , C10N10/06 , C10N10/08 , C10N10/10 , C10N10/12 , C10N10/16 , C10N30/06 , C10N40/08 , C10N40/20 , C10N40/25 , C10N50/10
CPC分类号： C10L10/08 , C07F19/005 , C07F5/04 , C07F5/069 , C07F7/006 , C07F9/005 , C07F9/902 , C08K5/0091 , C10L1/301 , C10L1/303 , C10L1/305 , C10L1/308 , C10L10/02 , C10M139/00 , C10M159/18 , C10M2201/02 , C10M2227/062 , C10M2227/09 , C10N2210/01 , C10N2210/02 , C10N2210/03 , C10N2210/04 , C10N2210/05 , C10N2210/06 , C10N2210/08 , C10N2240/06 , C10N2240/08 , C10N2240/40
摘要： Compositions comprisinga) a functional liquid or an internal combustion engine fuel andb) at least one compound of the general formula I ##STR1## wherein R.sub.1 is --(CH.sub.2 --X).sub.n R, where X=--S-- or --O--, n=0 or 1 to 18 carbon atoms, a phenyl group, a phenyl group which is substituted by at least one C.sub.1 -C.sub.18 alkyl group, a phenyl-C.sub.1 -C.sub.4 alkyl group or a phenyl-C.sub.1 -C.sub.4 alkyl group which is substituted by at least one C.sub.1 -C.sub.4 alkyl group, or R.sub.1 is an alkyl group of 1 to 18 carbon atoms which is substituted by at least one OH group, or R.sub.1 is a ##STR2## group in which the alkyl moiety contains 1 to 18 carbon atoms, and R.sub.2 and R.sub.3 are the same or different and are --H or, independently of R.sub.1, have the same meanings as R.sub.1, and M is B, Al, Fe, Cr, Sb or Bi, or M is a group M'--R' or a group M'--OR", where M' is Ti, Zr or Sn, and R' and R" is C.sub.1 -C.sub.18 alkyl or R' is ##STR3## wherein M' is defined above, and R.sub.1 ', R.sub.2 ' and R.sub.3 ' have the meanings of R.sub.1, R.sub.2 and R.sub.3, or R" is Li, Na or K or is ##STR4## wherein M' is as defined above and M" is Mg, Ca, B, Al, Fe, Cr, Sb, Bi, Zn, Ti, Ni or Cu, q has the valence of M", and R.sub.1 ', R.sub.2 ' and R.sub.3 ' have the respective meanings of R.sub.1, R.sub.2 and R, or M is --VO.The compounds of formula act, for example, in lubricants as antiwear additives and extreme pressure additives, and also as stabilizers for natural or regenerated polymers.
摘要翻译：组合物，其包含a）功能性液体或内燃机燃料和b）至少一种通式I的化合物其中R 1是 - （CH 2 -X）n R，其中X = -S-或 - O-，n = 0或1至18个碳原子，苯基，被至少一个C 1 -C 18烷基取代的苯基，苯基-C 1 -C 4烷基或被取代的苯基-C 1 -C 4烷基至少一个C 1 -C 4烷基，或R 1是被至少一个OH基团取代的具有1至18个碳原子的烷基，或者R 1是其中烷基部分含有1至18个碳原子的基团，R2和R3相同或不同，为-H或独立地为R1具有与R1相同的含义，M为B，Al，Fe，Cr，Sb或Bi，或M为M' R'或基团M'-OR“，其中M'是Ti，Zr或Sn，R'和R”是C 1 -C 18烷基或R'是其中M'定义如上，R1' ，R2'和R3'具有R 1，R 2和R 3的含义，或者R“是Li，Na或K，或者是” d，M“是Mg，Ca，B，Al，Fe，Cr，Sb，Bi，Zn，Ti，Ni或Cu，q具有M”的化合价，R1'，R2'和R3' R1，R2和R或M的相应含义为-VO。式中的化合物例如作为抗磨添加剂和极压添加剂的润滑剂，以及天然或再生聚合物的稳定剂。

5. 发明授权

US5457915A Tile saw shield 失效
标题翻译：便携式瓦锯屏蔽
公开(公告)号：US5457915A
公开(公告)日：1995-10-17
申请号：US6368
申请日：1993-01-19
申请人： Richard E. Voege
发明人： Richard E. Voege
IPC分类号： B23D59/02 , B23Q11/08 , B24B55/04
CPC分类号： B23D59/02 , B23Q11/08 , B23Q11/085 , B24B55/04
摘要： A transparent plastic shield for a tile saw includes four dismantable panels, two vertical side panels, a back panel and a top panel. The components are quickly assembled together via slotted edges or connecting extrusions and when dismantled stack flatly within the water tray which is included as part of the tile saw apparatus. The tile saw shield is configured to allow normal use of the tile saw, without encumbering the user. It contains water from spraying out of the tray, to the extent that the tile saw can be used in an interior setting.
摘要翻译：用于瓦片锯的透明塑料护罩包括四个可拆卸面板，两个垂直侧面板，后面板和顶板。组件通过开槽边缘或连接挤压件快速组装在一起，并且当拆卸的堆叠平坦地放置在作为瓦锯装置的一部分的水盘内时。瓦片锯屏蔽被配置为允许瓦片锯的正常使用，而不会使用户受到妨碍。它包含从托盘喷出的水，到瓷砖锯可以在室内使用的程度。

6. 发明授权

US5382659A Aromatic acids 失效
标题翻译：芳香酸
公开(公告)号：US5382659A
公开(公告)日：1995-01-17
申请号：US255298
申请日：1994-06-07
申请人： Jui Y. Chang
发明人： Jui Y. Chang
IPC分类号： C07C309/46 , C07C309/51 , C07C331/28 , G01N33/68 , C09B29/085
CPC分类号： G01N33/6818 , C07C309/46 , C07C309/51 , C07C331/28
摘要： The invention relates to novel aromatic acids, especially to compounds of formula ##STR1## wherein R.sub.1 is lower alkyl, R.sub.2 is lower alkyl, R.sub.3 is hydrogen, carboxy or sulfo, R.sub.4 is carboxy or sulfo, G is an unsubstituted or substituted 1,4-phenylene group or an unsubstituted or substituted 1,4-naphthylene group, and wherein either R.sub.5 and R.sub.6 together are an additional bond and L is an oxygen or sulfur atom or wherein R.sub.5 is hydrogen, R.sub.6 is halomethyl and L is an oxygen atom, and salts thereof, to the use of compounds I and their salts, to a process for the preparation of compounds I and their salts, to starting materials used in that preparation process, and salts thereof, to a process for the preparation of those starting materials and their salts, to a device in which the compounds I and their salts are used, and to a process in which that device is used. The compounds of formula I can be used as adjuncts in the investigation of proteins and can be prepared in a manner known per se.
摘要翻译：本发明涉及新的芳族酸，特别是涉及其中R 1为低级烷基，R 2为低级烷基，R 3为氢，羧基或磺基，R 4为羧基或磺基的式（I）化合物，G为未取代或取代的 1,4-亚苯基或未取代或取代的1,4-亚萘基，其中R 5和R 6一起是另外的键，L是氧或硫原子，或其中R 5是氢，R 6是卤代甲基，L是氧原子及其盐，使用化合物I及其盐，将化合物I及其盐的制备方法用于该制备方法中使用的原料及其盐，制备方法这些原料及其盐与使用化合物I及其盐的装置以及使用该装置的方法。式I化合物可用作蛋白质研究中的辅助物质，并且可以以本身已知的方式制备。

7. 发明授权

US5334583A Use of sugar derivatives for the prophylaxis and treatment of virus infections 失效
标题翻译：使用糖衍生物预防和治疗病毒感染
公开(公告)号：US5334583A
公开(公告)日：1994-08-02
申请号：US985087
申请日：1992-12-02
申请人： Bohumir Lukas , Karl H. S. Ruppin
发明人： Bohumir Lukas , Karl H. S. Ruppin
IPC分类号： C07K9/00 , A61K37/02
CPC分类号： C07K9/005
摘要： Described are the use of hexopyranose compounds of the formula I ##STR1## for the prophylaxis and treatment of virus infections, and novel pharmaceutical preparations especially suitable for the use in accordance with the invention.The substituents in formula I have the meanings given in the claims.
摘要翻译：描述了式I（I）的六吡喃糖类化合物用于预防和治疗病毒感染以及特别适用于本发明的新型药物制剂。式I中的取代基具有权利要求中给出的含义。

8. 发明授权

US5322852A Aminooxy piperidines as ornithine decarboxylase inhibitors 失效
标题翻译：氨基氧哌啶类作为鸟氨酸脱羧酶抑制剂
公开(公告)号：US5322852A
公开(公告)日：1994-06-21
申请号：US16407
申请日：1993-02-11
申请人： Jorg Frei , Jaroslav Stanek
发明人： Jorg Frei , Jaroslav Stanek
IPC分类号： A61K31/445 , A61K31/4458 , A61P33/02 , A61P35/00 , A61P43/00 , C07D211/22 , C07D211/42 , C07D211/46 , C07D211/26 , C07D211/40
CPC分类号： C07D211/22 , C07D211/46
摘要： The invention relates to compounds of formula I ##STR1## wherein either R.sub.1 is a radical of formula Ia,--(CH.sub.2).sub.n --O--NH.sub.2 (Ia)in which n is 0 or 1, is hydrogen and R.sub.2 is a radical of formula Ib,--(CH.sub.2).sub.p --O--NH.sub.2 (Ib)in which p is 1 or 2, and wherein R is C.sub.1 -C.sub.2 alkyl which is attached to one carbon atom of the central piperidine ring system, but not to the same carbon atom as R.sub.1 of formula Ia or as R.sub.2 of formula Ib; and m is 1 or 2, and salts thereof. The invention further relates to the preparation of these compounds, to intermediates obtained during their synthesis, to pharmaceutical compositions which contain them, and to the use of said compounds for the therapeutic treatment of the human or animal body and for the preparation of pharmaceutical compositions.The compounds of formula I are inhibitors of ornithin decarboxylase.
摘要翻译：本发明涉及式I化合物其中R 1为式Ia基团， - （CH 2）n O-NH 2（Ia），其中n为0或1，为氢，R 2为式Ib， - （CH 2）p O-NH 2（Ib），其中p是1或2，并且其中R是连接到中心哌啶环体系的一个碳原子但不与碳原子相同的C 1 -C 2烷基，式Ia的R 1或式Ib的R 2; 和m为1或2，及其盐。本发明还涉及这些化合物，其在合成期间获得的中间体，其含有它们的药物组合物的制备，以及所述化合物用于人或动物体的治疗和用于制备药物组合物的用途。式I化合物是鸟氨酸脱羧酶的抑制剂。

9. 发明授权

US5310743A 1-acylpiperidine compounds 失效
标题翻译： 1-酰基哌啶化合物
公开(公告)号：US5310743A
公开(公告)日：1994-05-10
申请号：US929186
申请日：1992-08-11
申请人： Walter Schilling , Silvio Ofner , Siem J. Veenstra
发明人： Walter Schilling , Silvio Ofner , Siem J. Veenstra
IPC分类号： C07D211/26 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/445 , A61K31/451 , A61K31/452 , A61K31/4523 , A61K31/4525 , A61K31/4535 , A61K31/454 , A61K31/47 , A61K31/4709 , A61P1/00 , A61P11/08 , A61P25/00 , A61P25/04 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/26 , A61P27/02 , A61P29/00 , A61P43/00 , C07D20060101 , C07D211/58 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/12 , C07D471/04 , C07D215/12 , A01N43/42 , C07D215/16
CPC分类号： C07D401/12 , C07D211/58 , C07D401/14 , C07D405/12 , C07D409/12 , C07D471/04
摘要： 1-Acylpiperidine compound of the formula I ##STR1## in which R.sub.1 is an optionally substituted aralkyl, aryloxyalkyl, heteroaralkyl, aroyl, heteroaroyl, cycloalkylcarbonyl, aralkanoyl, heteroarylalkanoyl, aralkoxycarbonyl or arylcarbamoyl radical or the acyl radical of an .alpha.-amino acid which is optionally N-substituted by lower alkanoyl or carbamoyl-lower-alkanoyl, R.sub.2 is cycloalkyl or an optionally substituted aryl or heteroaryl radical, R.sub.3 is hydrogen, alkyl, carbamoyl or an alkanoyl or alkenoyl radical which is optionally substituted by carboxyl or esterified or amidated carboxyl, R.sub.4 is an optionally substituted aryl or optionally partially hydrogenated heteroaryl radical, X.sub.1 is methylene, ethylene, a direct linkage, an optionally ketalised carbonyl group or an optionally etherified hydroxymethylene group, X.sub.2 is alkylene, carbonyl or a direct linkage, and X.sub.3 is carbonyl, oxo-lower-alkylene, oxo(aza)-lower-alkylene or an alkylene radical which is optionally substituted by phenyl, hydroxymethyl, optionally esterified or amidated carboxyl or, in higher than the .alpha. position, by hydroxyl, and its salts have substance-P-antagonistic properties and can be used as pharmaceutically active substances in pharmaceuticals for the treatment of disorders in whose development substance P plays an essential part.
摘要翻译：式I的1-酰基哌啶化合物其中R 1是任选取代的芳烷基，芳氧基烷基，杂芳烷基，芳酰基，杂芳酰基，环烷基羰基，芳烷酰基，杂芳基烷酰基，芳烷氧基羰基或芳基氨基甲酰基或α-氨基的酰基酸，其任选被低级烷酰基或氨基甲酰基 - 低级 - 烷酰基N-取代，R 2是环烷基或任选取代的芳基或杂芳基，R 3是氢，烷基，氨基甲酰基或任选被羧基或酯化的烷酰基或烯酰基或酰胺化的羧基，R 4是任选取代的芳基或任选部分氢化的杂芳基，X 1是亚甲基，亚乙基，直链，任选的缩酮化羰基或任选醚化的羟基亚甲基，X 2是亚烷基，羰基或直链， X 3是羰基，氧代 - 低级 - 亚烷基，氧代（氮杂） - 低级 - 亚烷基或任选被苯基取代的亚烷基，羟甲基，任选酯化或酰胺化的羧基，或高于α位置的羟基，其盐具有物质P-拮抗性质，可用作药物中的药物活性物质，用于治疗其发育物质P所起的障碍一个重要的部分。

10. 再颁专利

USRE32347E Hypocalcaemic peptides and process for their manufacture 失效
标题翻译：低血糖肽及其制造方法
公开(公告)号：USRE32347E
公开(公告)日：1987-02-03
申请号：US644696
申请日：1984-08-27
申请人： Robert Neher , Bernhard Riniker
发明人： Robert Neher , Bernhard Riniker
IPC分类号： A61K38/00 , C07K14/585
CPC分类号： C07K14/585 , A61K38/00
摘要： Human calcitonin in the form of four components and process for their isolation from C-cells material.

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