专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

81. 发明申请

US20050061678A1 Treatment of humans with colloidal silver composition 有权
标题翻译：用胶体银组合物治疗人体
公开(公告)号：US20050061678A1
公开(公告)日：2005-03-24
申请号：US10641938
申请日：2003-08-15
申请人： Robert Holladay , Herbert Christensen , William Moeller
发明人： Robert Holladay , Herbert Christensen , William Moeller
IPC分类号： A61K9/00 , A61K33/38 , A61K33/40 , A61K45/06 , A61K47/10 , A61K47/32 , A61L2/16 , A61L2/238 , B01F7/22 , B01F13/00 , B01J13/00 , B01J19/08 , B01J19/18 , C02F1/46 , A61K9/10
CPC分类号： A61K9/0046 , A61K9/0014 , A61K9/0034 , A61K9/0043 , A61K9/0095 , A61K33/38 , A61K33/40 , A61K45/06 , A61K47/10 , A61K47/32 , A61L2/16 , A61L2/186 , A61L2/238 , B01F7/22 , B01F13/0001 , B01F13/0003 , B01J13/0043 , B01J19/087 , B01J19/18 , B01J2219/082 , B01J2219/0835 , B01J2219/0841 , B01J2219/089 , C02F1/4606 , C02F2303/04 , Y10S514/849 , Y10S514/858 , Y10S514/894 , Y10S514/895 , Y10S514/924 , Y10S514/931 , Y10S514/932 , Y10S514/934 , Y10S514/951 , A61K2300/00
摘要： We disclose a colorless composition comprising silver particles and water, wherein said particles comprise an interior of elemental silver and an exterior of ionic silver oxide, wherein the silver particles are present in the water at a level of about 5-40 ppm, and wherein the composition manifests significant antimicrobial properties. Methods of use of the composition are described.
摘要翻译：我们公开了包含银颗粒和水的无色组合物，其中所述颗粒包含元素银的内部和离子氧化银的外部，其中银颗粒以约5-40ppm的水平存在于水中，并且其中组合表现出显着的抗菌性能。描述了组合物的使用方法。

82. 发明申请

US20050048557A1 Chlamydia protein, gene sequence and uses thereof 失效
标题翻译：衣原体蛋白，基因序列及其用途
公开(公告)号：US20050048557A1
公开(公告)日：2005-03-03
申请号：US10931779
申请日：2004-09-01
申请人： W. Jackson , John Pace
发明人： W. Jackson , John Pace
IPC分类号： G01N33/563 , A61K31/711 , A61K38/00 , A61K39/00 , A61K39/118 , A61K39/395 , A61K39/40 , A61K48/00 , A61P31/04 , A61P43/00 , C07K14/295 , C07K16/12 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12Q1/68 , G01N33/569 , G01N33/571 , A61K39/02 , C07H21/04
CPC分类号： G01N33/56927 , A61K38/00 , A61K39/00 , C07K14/295 , C07K16/125 , G01N2333/295 , Y10S514/885 , Y10S514/931 , Y10S514/937 , Y10S530/811 , Y10S530/814 , Y10S530/82
摘要： A high molecular weight (“HMW”) protein of Chlamydia, the amino acid sequence thereof, and antibodies that specifically bind the HMW protein are disclosed as well as the nucleic acid sequence encoding the same. Also disclosed are prophylactic and therapeutic compositions, comprising the HMW protein, a fragment thereof, or an antibody that specifically binds the HMW protein or a portion thereof, or the nucleotide sequence encoding the HMW protein or a fragment thereof, including vaccines.
摘要翻译：公开了衣原体的高分子量（“HMW”）蛋白，其氨基酸序列和特异性结合HMW蛋白的抗体以及编码该HMW蛋白的核酸序列。还公开了包含HMW蛋白，其片段或特异性结合HMW蛋白或其部分的抗体或编码HMW蛋白或其片段（包括疫苗）的核苷酸序列的预防和治疗组合物。

83. 发明授权

US06835717B2 &bgr;-cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases 有权
标题翻译： β-环糊精组合物，以及用于预防性传播疾病的传播
公开(公告)号：US06835717B2
公开(公告)日：2004-12-28
申请号：US09802779
申请日：2001-03-08
申请人： James E. Hildreth
发明人： James E. Hildreth
IPC分类号： A61K4304
CPC分类号： A61K45/06 , A61K9/0034 , A61K31/724 , Y10S514/841 , Y10S514/931 , Y10S514/934 , A61K2300/00
摘要： Methods of reducing the risk of transmission of a sexually transmitted pathogen by contacting the pathogen or cells susceptible to infection by the pathogen with a &bgr;-cyclodextrin are provided. Methods for reducing the risk of transmission of a sexually transmitted pathogen to or from a subject by contacting the pathogen or cells susceptible to the pathogen in the subject with a pharmaceutical composition containing a &bgr;-cyclodextrin also are provided. Accordingly, pharmaceutical compositions, which include 1) a &bgr;-cyclodextrin, which is in an amount that blocks passage of the pathogen through lipid rafts in the membrane of a cell susceptible to the pathogen, and 2) a contraceptive, an agent for treating a sexually transmitted disease, a lubricant, or a combination thereof, are provided, as are composition formulated from a solid substrate that contains an amount of &bgr;-cyclodextrin useful for reducing the risk of transmission of a sexually transmitted pathogen.

84. 发明申请

US20040186183A1 Anti-infective compositions, methods and systems for treating pathogen-induced disordered tissues 有权
标题翻译：用于治疗病原体诱导的无序组织的抗感染组合物，方法和系统
公开(公告)号：US20040186183A1
公开(公告)日：2004-09-23
申请号：US10816571
申请日：2004-04-01
发明人： B. Ron Johnson
IPC分类号： A61K031/155
CPC分类号： A61K31/055 , A61K9/0014 , A61K31/155 , A61K31/205 , A61K31/4425 , A61K31/522 , A61K31/53 , A61K31/675 , A61K31/7072 , A61K31/7076 , A61K45/06 , A61K47/08 , A61K47/10 , A61M35/003 , Y10S514/931 , Y10S514/934
摘要： Compositions, methods and systems for treating disordered epithelial tissues, such as is caused by pathogens and/or by toxins produced thereby. The invention relates to the use of an anti-infective and/or antimicrobial active agent in a carrier, with vigorous agitation of the disordered epithelial tissue for topical treatment thereof under such conditions sufficient to achieve clinically discernable improvement of the disordered epithelial tissue. The preferred anti-infective and/or antimicrobial active agent comprises an organohalide, such as a quaternary ammonium halide compound, preferably benzalkonium chloride. The inventive compositions and methods may employ the use of an applicator adapted for use in promoting the penetration of the treatment composition and/or the vigorous agitation of the disordered tissue.
摘要翻译：用于治疗无序上皮组织的组合物，方法和系统，例如由病原体和/或由此产生的毒素引起的。本发明涉及抗感染和/或抗微生物活性剂在载体中的用途，剧烈搅动无序上皮组织用于局部治疗，在足以实现无序上分解的无序上皮组织改善的条件下。优选的抗感染和/或抗微生物活性剂包括有机卤化物，例如卤化季铵化合物，优选苯扎氯铵。本发明的组合物和方法可以使用适于用于促进治疗组合物的渗透和/或无序组织的剧烈搅动的施用器。

85. 发明申请

US20040157073A1 Lubricious coatings for substrates 审中-公开
公开(公告)号：US20040157073A1
公开(公告)日：2004-08-12
申请号：US10772672
申请日：2004-02-05
申请人： Nucryst Pharmaceuticals Corp., a Alberta, Canada corporation
发明人： Robert Edward Burrell , Hua Qing Yin , Antony George Naylor , Peter Howard Moxham , Walter Carlton Theodore Cholowski , Leonard Salvin Bowlby , David James Field
IPC分类号： C23C020/00
CPC分类号： A61K9/0024 , A01N59/16 , A61K9/0019 , A61K9/0075 , A61K9/0078 , A61K9/14 , A61K9/7007 , A61K33/24 , A61K33/38 , A61K33/40 , A61K47/34 , A61K47/38 , A61L15/46 , A61L17/145 , A61L27/30 , A61L29/10 , A61L31/082 , A61L2300/102 , A61L2300/104 , A61L2300/404 , A61L2300/452 , A61L2300/606 , A61L2300/624 , A61L2300/63 , Y10S424/15 , Y10S514/825 , Y10S514/826 , Y10S514/829 , Y10S514/83 , Y10S514/849 , Y10S514/851 , Y10S514/853 , Y10S514/861 , Y10S514/862 , Y10S514/864 , Y10S514/865 , Y10S514/88 , Y10S514/881 , Y10S514/882 , Y10S514/886 , Y10S514/887 , Y10S514/90 , Y10S514/901 , Y10S514/902 , Y10S514/912 , Y10S514/914 , Y10S514/925 , Y10S514/931 , Y10S514/932 , Y10S514/933 , Y10S514/934 , Y10S514/944 , Y10S514/951 , Y10S514/953 , Y10S514/954 , Y10S514/956 , Y10S514/958 , Y10S514/964 , Y10S514/965 , Y10S514/966 , Y10S514/967 , Y10S514/968 , Y10S514/969 , Y10T428/31855 , A61K2300/00 , A01N25/04 , A01N25/10 , A01N25/12
摘要： The invention provides methods and kits to form water swellable gel coatings, preferably lubricious coatings, on substrates, and coated substrates thus formed. The coatings contain one or more antimicrobial metals formed with atomic disorder, together with one or more antimicrobial metals formed with atomic disorder such that the coatings provide an antimicrobial and anti-inflammatory effect when wet. The invention also provides a method to produce metal powders by sputtering a coating onto a moving surface, and then scraping the coating with one or more scrapers to produce the metal powder. The method is particularly useful for producing large amounts of nanocrystalline antimicrobial metal powders formed with atomic disorder, useful in the water swellable gel coatings of this invention.

86. 发明授权

US06770635B1 Method for medicating the inflammatory controlling system and adverse inflammatory reactions and for making compounds for treating the pathology of adverse inflammatory reactions 失效
标题翻译：用于治疗炎症控制系统和不良炎症反应以及用于治疗不良炎症反应病理的化合物的方法
公开(公告)号：US06770635B1
公开(公告)日：2004-08-03
申请号：US08984947
申请日：1997-12-04
申请人： Clairmont G. Drube
发明人： Clairmont G. Drube
IPC分类号： A61K3170
CPC分类号： A61K31/7012 , Y10S514/814 , Y10S514/826 , Y10S514/86 , Y10S514/861 , Y10S514/863 , Y10S514/866 , Y10S514/884 , Y10S514/885 , Y10S514/886 , Y10S514/893 , Y10S514/912 , Y10S514/931 , Y10S514/934
摘要： Adverse inflammatory reactions can be treated by administrating to an organism a composition having diglucosylamine as the active ingredient. The preferred compound is di-Beta-D-glucopyranosylamine. A simple method for making diglucosylamine in high purity is obtained by reacting glucose, a nitrogen containing base, and either methanol or ethanol to form the diglucosylamine and then recovering the diglucosylamine preferably with the use of charcoal. The preferred diglucosylamine, di-Beta-D-glucopyranosylamine, has extraordinary anti-inflammatory activity. It can be formulated with a pharmaceutically acceptable carrier to make pharmaceutical compositions which are effective in treating inflammations. This pharmaceutical composition can also be used to treat adverse inflammatory reactions that are the result of the disruptions of a dynamic network of cellular mechanisms in organisms. In addition, application of this composition also serves to reestablish the balance of the cellular defense network in an organism which has its cellular defense network out of balance. In this unbalanced case, the composition serves to treat the pathology of inflammation and activates the inflammatory control system in vivo. These adverse inflammatory reactions can also be treated by administrating to the organism glucose in the presence of NH3+ ions and at a pH of about 7.0 or greater. The glucose can preferably be applied by orally administrating an enteric-coated form of glucose, alone or in combination with other medicaments.
摘要翻译：可以通过向生物体施用具有二葡糖胺作为活性成分的组合物来治疗不良反应。优选的化合物是二-β-D-吡喃葡萄糖胺。通过使葡萄糖，含氮碱和甲醇或乙醇反应形成二葡糖胺，然后优选利用木炭回收二葡糖胺，从而获得制备高纯度二葡糖胺的简单方法。优选的二葡糖胺，二-β-D-吡喃葡萄糖胺具有非凡的抗炎活性。其可以与药学上可接受的载体配制以制备有效治疗炎症的药物组合物。该药物组合物也可用于治疗由于生物体中细胞机制的动态网络的破坏而引起的不良炎症反应。此外，该组合物的应用还用于重建其细胞防御网络不平衡的生物体中的细胞防御网络的平衡。在这种不平衡的情况下，该组合物用于治疗炎症的病理学并在体内激活炎症控制系统。这些不利的炎症反应也可以通过在NH 3 +离子的存在下并且在约7.0或更高的pH下施用于生物体葡萄糖来治疗。优选通过单独或与其它药物组合口服施用肠溶包衣形式的葡萄糖来施用葡萄糖。

87. 发明授权

US06743773B2 Method of using lectins for contraception, prophylaxis against diseases transmittable by sexual contact, and therapy of such diseases, and apparatus for administering lectins 失效
标题翻译：使用凝集素进行避孕的方法，通过性接触传播的疾病的预防和这些疾病的治疗，以及用于施用凝集素的装置
公开(公告)号：US06743773B2
公开(公告)日：2004-06-01
申请号：US10259610
申请日：2002-09-30
申请人： Michael J. Oldham , Bruce F. Rose
发明人： Michael J. Oldham , Bruce F. Rose
IPC分类号： A01N3718
CPC分类号： A61K38/17 , A61F6/08 , A61K38/168 , A61K38/1709 , Y10S424/14 , Y10S514/841 , Y10S514/843 , Y10S514/931 , Y10S514/932 , Y10S514/933 , Y10S514/934 , Y10S514/953 , Y10S514/967 , Y10T428/31971
摘要： In order to prevent conception and/or the spread of sexually transmitted diseases (STD's) one or more lectins capable of binding sperm and/or the pathogenic microorganisms responsible for STD's are administered to the vagina prior to sexual intercourse. The lectins immobilize the sperm to render them incapable of fertilization and also bind to the microorganisms to render them non-pathogenic or to the cells to prevent infection by the microorganisms. Lectins can also be administered to treat sexually transmitted vaginal infections. The invention also encompasses a device for to be placed in the vault of the vagina which comprises a ring which surrounds the cervix and a membrane spanning the central aperture of the ring to prevent the direct contact of ejaculate with the cervical tissues. The device is impregnated or coated with lectins and releases them into the vaginal environment over a period of time.
摘要翻译：为了防止性传播疾病（STD's）的受孕和/或扩散，可以在性交前向阴道施用一种或多种能够结合精子和/或负责STD的病原微生物的凝集素。凝集素固定精子使其不能施肥，并且还结合微生物使其成为非致病性或细胞以防止微生物感染。也可以施用凝露素治疗性传播的阴道感染。本发明还包括用于放置在阴道的拱顶中的装置，其包括围绕子宫颈的环和横跨环的中心孔的膜，以防止射精与子宫颈组织的直接接触。该装置浸渍或涂有凝集素，并在一段时间内将其释放到阴道环境中。

88. 发明授权

US06656936B1 Carnitine analogues as topical, microbicidal spermicides 失效
标题翻译：肉碱类似物作为局部，杀微生物杀精剂
公开(公告)号：US06656936B1
公开(公告)日：2003-12-02
申请号：US10049882
申请日：2002-07-05
申请人： Prashant S. Savle , Richard D. Gandour , Gustavo F. Doncel
发明人： Prashant S. Savle , Richard D. Gandour , Gustavo F. Doncel
IPC分类号： A61K31535
CPC分类号： C07D265/32 , A61K9/0034 , A61K31/19 , A61K31/535 , A61K31/5375 , Y10S514/841 , Y10S514/843 , Y10S514/931 , Y10S514/934 , Y10S514/944 , Y10S514/967 , A61K2300/00
摘要： Acylcarnitine analogues having alkyl side chains of 10 to 30 carbon atoms display excellent spermicidal and anti-HIV activity, a well as being potent inhibitors of the growth of Candida albicans.
摘要翻译：具有10至30个碳原子的烷基侧链的酰基肉碱类似物显示出优异的杀精和抗HIV活性，以及作为白念珠菌生长的有效抑制剂。

89. 发明申请

US20030099718A1 Treatment of mucosal membranes 有权
标题翻译：治疗粘膜
公开(公告)号：US20030099718A1
公开(公告)日：2003-05-29
申请号：US10131509
申请日：2002-04-23
发明人： Robert Edward Burrell , Antony George Naylor , Peter Howard Moxham
IPC分类号： A61K033/38 , A61K033/24 , A61L009/04
CPC分类号： A61K9/0024 , A01N59/16 , A61K9/0019 , A61K9/0075 , A61K9/0078 , A61K9/14 , A61K9/7007 , A61K33/24 , A61K33/38 , A61K33/40 , A61K47/34 , A61K47/38 , A61L15/46 , A61L17/145 , A61L27/30 , A61L29/10 , A61L31/082 , A61L2300/102 , A61L2300/104 , A61L2300/404 , A61L2300/452 , A61L2300/606 , A61L2300/624 , A61L2300/63 , Y10S424/15 , Y10S514/825 , Y10S514/826 , Y10S514/829 , Y10S514/83 , Y10S514/849 , Y10S514/851 , Y10S514/853 , Y10S514/861 , Y10S514/862 , Y10S514/864 , Y10S514/865 , Y10S514/88 , Y10S514/881 , Y10S514/882 , Y10S514/886 , Y10S514/887 , Y10S514/90 , Y10S514/901 , Y10S514/902 , Y10S514/912 , Y10S514/914 , Y10S514/925 , Y10S514/931 , Y10S514/932 , Y10S514/933 , Y10S514/934 , Y10S514/944 , Y10S514/951 , Y10S514/953 , Y10S514/954 , Y10S514/956 , Y10S514/958 , Y10S514/964 , Y10S514/965 , Y10S514/966 , Y10S514/967 , Y10S514/968 , Y10S514/969 , Y10T428/31855 , A61K2300/00 , A01N25/04 , A01N25/10 , A01N25/12
摘要： The invention relates to the use of one or more antimicrobial metals preferably selected from silver, gold, platinum, and palladium but most preferably silver, formed with atomic disorder, and preferably in a nanocrystalline form, for reducing inflammation or infection of the mucosal membrane. The antimicrobial metal may be formulated as, or used in the form of, a nanocrystalline coating of one or more antimicrobial or noble metals, a nanocrystalline powder of one or more antimicrobial or noble metals, or a liquid or solution containing dissolved species from a nanocrystalline powder or coating of one or more antimicrobial or noble metals.
摘要翻译：本发明涉及一种或多种优选选自银，金，铂和钯但最优选银的抗微生物金属的用途，其以原子紊乱形成，优选以纳米晶形式形成，用于减少粘膜的炎症或感染。抗微生物金属可以配制成一种或多种抗微生物或贵重金属的纳米晶体涂层，或一种或多种抗微生物或贵金属的纳米晶体粉末，或含有纳米晶体的溶解物质的液体或溶液一种或多种抗微生物或贵金属的粉末或涂层。

90. 发明申请

US20030086977A1 Therapeutic treatments using the direct application of antimicrobial metal compositions 失效
标题翻译：使用直接应用抗微生物金属组合物的治疗方法
公开(公告)号：US20030086977A1
公开(公告)日：2003-05-08
申请号：US10128208
申请日：2002-04-23
发明人： Scott H. Gillis
IPC分类号： A61K033/38 , A61K009/14
CPC分类号： A61K9/0024 , A01N59/16 , A61K9/0019 , A61K9/0075 , A61K9/0078 , A61K9/14 , A61K9/7007 , A61K33/24 , A61K33/38 , A61K33/40 , A61K47/34 , A61K47/38 , A61L15/46 , A61L17/145 , A61L27/30 , A61L29/10 , A61L31/082 , A61L2300/102 , A61L2300/104 , A61L2300/404 , A61L2300/452 , A61L2300/606 , A61L2300/624 , A61L2300/63 , Y10S424/15 , Y10S514/825 , Y10S514/826 , Y10S514/829 , Y10S514/83 , Y10S514/849 , Y10S514/851 , Y10S514/853 , Y10S514/861 , Y10S514/862 , Y10S514/864 , Y10S514/865 , Y10S514/88 , Y10S514/881 , Y10S514/882 , Y10S514/886 , Y10S514/887 , Y10S514/90 , Y10S514/901 , Y10S514/902 , Y10S514/912 , Y10S514/914 , Y10S514/925 , Y10S514/931 , Y10S514/932 , Y10S514/933 , Y10S514/934 , Y10S514/944 , Y10S514/951 , Y10S514/953 , Y10S514/954 , Y10S514/956 , Y10S514/958 , Y10S514/964 , Y10S514/965 , Y10S514/966 , Y10S514/967 , Y10S514/968 , Y10S514/969 , Y10T428/31855 , A61K2300/00 , A01N25/04 , A01N25/10 , A01N25/12
摘要： Therapeutic treatments using the direct application of selected structures of antimicrobial metals in free-standing powder form, solution form and/or suspension form in therapeutically effective amounts. The selected structures of antimicrobial metals serve as an antimicrobial agent, an anti-inflammatory agent, an immuno modulator agent, an enzyme modulator agent, and/or an anti-tumor agent, for human and/or animal use.
摘要翻译：使用以治疗有效量直接施用选择的抗微生物金属结构的自由粉末形式，溶液形式和/或悬浮液形式的治疗性治疗。抗微生物金属的所选结构用作人和/或动物使用的抗微生物剂，抗炎剂，免疫调节剂，酶调节剂和/或抗肿瘤剂。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式