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81. 发明授权

US09061146B2 Impedance-based bladder sensing 有权
标题翻译：基于阻抗的膀胱感觉
公开(公告)号：US09061146B2
公开(公告)日：2015-06-23
申请号：US11261443
申请日：2005-10-28
申请人： Martin T. Gerber
发明人： Martin T. Gerber
IPC分类号： A61N1/32 , A61N1/36 , A61B5/053 , A61B5/00 , A61N1/372 , A61B5/20
CPC分类号： A61N1/36007 , A61B5/053 , A61B5/0538 , A61B5/20 , A61B5/204 , A61B5/6874 , A61N1/37252
摘要： Systems that sense the volume, activity or other parameters of the urinary bladder are described. The systems include at least two electrodes that are implanted at respective locations proximate the wall of the bladder, and may be located substantially opposite each other with respect to a center of the bladder. At least one of the electrodes receives an electrical signal emitted by another of the electrodes. Systems according to the invention detect an impedance through the bladder based on the signal, e.g., based on one or both of the current or voltage of the signal. Based on the detected impedance, the systems sense one or more parameters of the bladder, such as volume, activity, or the like, which influence the impedance. The detected impedance, or bladder parameter information derived from the impedance, may be stored for short- or long-term monitoring, or used to control delivery of a therapy to a patient.
摘要翻译：描述了感测膀胱体积，活性或其他参数的系统。这些系统包括至少两个电极，其被植入在邻近囊的壁的相应位置处，并且可以相对于膀胱的中心彼此基本相对。至少一个电极接收由另一个电极发射的电信号。根据本发明的系统例如基于信号的电流或电压中的一个或两个，基于信号检测通过膀胱的阻抗。基于检测到的阻抗，系统感测膀胱的一个或多个参数，例如影响阻抗的体积，活动度等。可以存储从阻抗导出的检测到的阻抗或膀胱参数信息用于短期或长期监测，或用于控制对患者的治疗递送。

82. 发明申请

US20150099999A1 SYSTEM AND METHOD FOR MEASURING FEMALE URETHRAL LENGTH 有权
标题翻译：用于测量女性尿道长度的系统和方法
公开(公告)号：US20150099999A1
公开(公告)日：2015-04-09
申请号：US14505633
申请日：2014-10-03
申请人： Personal Medical Corp.
发明人： Kevin M. Connolly , Lee Brody , Sagi Brink-Danan
IPC分类号： A61B5/107 , A61B5/20
CPC分类号： A61B5/1076 , A61B5/202 , A61B5/6874 , A61M2210/1089 , A61M2210/1092 , A61M2210/1096
摘要： In one embodiment, a device measures the length of the urethra. The device includes a hollow tube having markings, wherein the hollow tube includes an internal end and an external end. The internal end includes one or more fins that can be manipulated into an open position and a closed position. The external end includes an opening allowing the insertion of a push-tube sliding axially within the body of the hollow tube, the push-tube being used to manipulate the fins into the open and closed positions. Further, an outer ring moves axially along the exterior of hollow tube and is utilized to measure the length of the urethra.
摘要翻译：在一个实施例中，装置测量尿道的长度。该装置包括具有标记的中空管，其中中空管包括内端和外端。内部端部包括可以被操纵到打开位置和关闭位置的一个或多个翅片。外端包括允许插入沿中空管的主体内的轴向滑动的开口的开口，该推动管用于将翅片操纵到打开和关闭位置。此外，外环沿着中空管的外部轴向移动并且用于测量尿道的长度。

83. 发明授权

US08588930B2 Piezoelectric stimulation device 有权
标题翻译：压电刺激装置
公开(公告)号：US08588930B2
公开(公告)日：2013-11-19
申请号：US12661949
申请日：2010-03-26
申请人： Anthony DiUbaldi , Stephen Wahlgren , Michael R. Tracey
发明人： Anthony DiUbaldi , Stephen Wahlgren , Michael R. Tracey
IPC分类号： A61N1/36
CPC分类号： A61N1/36014 , A61B5/6874 , A61B2562/028 , A61H23/0245 , A61H2201/5005 , A61N1/32 , A61N1/36007 , A61N1/36017 , A61N1/3787
摘要： A method for stimulating a predetermined body part such as a nerve using a stimulation device including an external non-implantable transmitting device powered by a power source and generating an electrical waveform signal. A surface electrode applies the generated electrical waveform signal transcutaneously. An implantable piezoelectric element receives the applied electrical waveform signal generated transcutaneously and, in turn, causes mechanical deformation resulting in mechanical vibration of the implantable piezoelectric element sufficient to stimulate the predetermined body part. The electrical waveform signal may be either a high frequency continuous waveform or high frequency burst packets.
摘要翻译：一种使用包括由电源供电的外部非植入式发送装置的刺激装置来刺激诸如神经的预定身体部位并产生电波形信号的方法。表面电极经常地施加所生成的电波形信号。可植入式压电元件接收经过生成的施加的电波形信号，从而导致机械变形，导致可植入式压电元件的机械振动足以刺激预定的身体部位。电波形信号可以是高频连续波形或高频突发分组。

84. 发明授权

US08128576B2 System and method for urodynamic evaluation utilizing micro electro-mechanical system technology 有权
标题翻译：使用微机电系统技术进行尿动力学评估的系统和方法
公开(公告)号：US08128576B2
公开(公告)日：2012-03-06
申请号：US11635403
申请日：2006-12-07
申请人： Michael R. Tracey , Anthony DiUbaldi , Stephen Wahlgren , Rex O. Bare , Bradley J. Sargent
发明人： Michael R. Tracey , Anthony DiUbaldi , Stephen Wahlgren , Rex O. Bare , Bradley J. Sargent
IPC分类号： A61B5/00 , A61B1/307
CPC分类号： A61B5/14507 , A61B5/0031 , A61B5/205 , A61B5/208 , A61B5/6874 , A61B2562/028
摘要： An implantable urodynamic system includes an implantable first device deployable in a patient's bladder, an implantable second device deployable in a patient's vaginal canal, and a data acquisition and analysis module or processing unit external to the body of the patient. The first device includes a magnet and an inductive coil, and the second device includes a magnet, an inductive coil and a battery. When deployed in the patient's body, attraction between the magnets maintains the two devices in close proximity to one another to effect an inductive coupling between the coils so that the first device may be powered by the battery of the second device. The urodynamic system is intended to facilitate measurement, collection, and wireless transmission of real-time, or near real-time, data (bladder pressure, abdominal pressure, and temperature) from an ambulatory patient. This data is of value in diagnosing a number of abnormal bladder conditions, such as infection, overactive bladder, bladder spasms, and the like.
摘要翻译：可植入尿动力系统包括可部署在患者膀胱中的可植入第一装置，可植入患者阴道内的可植入第二装置，以及在患者身体外部的数据采集和分析模块或处理单元。第一装置包括磁体和感应线圈，并且第二装置包括磁体，感应线圈和电池。当部署在患者体内时，磁体之间的吸引力将两个装置彼此紧密地保持在彼此附近以实现线圈之间的感应耦合，使得第一装置可以由第二装置的电池供电。尿动力系统旨在便于来自流动患者的实时或近实时数据（膀胱压力，腹压和温度）的测量，收集和无线传输。该数据在诊断膀胱膀胱状况异常，例如感染，膀胱过度活动症，膀胱痉挛等中是有价值的。

85. 发明申请

US20120035595A1 URETHRAL CATHETER FOR MEASURING THE PRESSURE INSIDE THE BLADDER OF A LIVING BEING 审中-公开
标题翻译：用于测量生活在叶子中的压力的URETHRAL导管
公开(公告)号：US20120035595A1
公开(公告)日：2012-02-09
申请号：US13263817
申请日：2010-03-25
申请人： Oliver Goedje , Manu Malbrain
发明人： Oliver Goedje , Manu Malbrain
IPC分类号： A61M27/00
CPC分类号： A61M25/0017 , A61B5/205 , A61B5/6874 , A61M25/1011 , A61M2025/0002 , A61M2025/0003
摘要： A urinary catheter for measuring the pressure in the bladder of a living being comprises a gas-filled measurement balloon for sensing bladder pressure which is arranged on the catheter body distally from a blocking balloon. The catheter body is locally reinforced in the region of the measurement balloon by a reinforcement ring in order to avoid effects of a local deformation of the catheter body on the measurement result. Similarly to conventional Foley catheters, the blocking balloon primarily prevents the urinary catheter from being withdrawn too far from the bladder, which is undesirable. Owing to a suitably selected distance d, which is preferably 3 cm or less, between the measurement balloon and the blocking balloon, the latter is protected from becoming trapped between a fold in the bladder.
摘要翻译：用于测量活体膀胱中的压力的导尿管包括用于感测膀胱压力的充气测量气囊，其布置在远离阻塞球囊的导管体上。导管体通过加强环在测量气囊的区域局部增强，以避免导管体的局部变形对测量结果的影响。与传统的Foley导管类似，阻塞气囊主要防止导尿管从膀胱中撤出太远，这是不期望的。由于在测量球囊和阻塞球囊之间适当选择的距离d（优选为3cm或更小），所以其保护不会被困在膀胱中的折叠之间。

86. 发明申请

US20070282184A1 Bladder Mapping 审中-公开
标题翻译：膀胱贴图
公开(公告)号：US20070282184A1
公开(公告)日：2007-12-06
申请号：US10596934
申请日：2005-01-11
申请人： Paul Roberts
发明人： Paul Roberts
IPC分类号： A61B5/05
CPC分类号： A61B5/6874 , A61B5/04884 , A61B5/6853 , A61B5/6858 , A61B18/1492 , A61B2018/00214 , A61B2018/00505
摘要： A device is provided for detecting the location of electrical activity in the wall of the human bladder. In a preferred embodiment the device is insertable through the urethra, and is expandable. The device may further include an ablation tool for ablating the interior wall of the bladder at a site of electrical activity.
摘要翻译：提供了用于检测人膀胱壁中电活动位置的装置。在优选实施例中，该装置可以通过尿道插入并且是可扩张的。该装置还可以包括消融工具，用于在电活动位置烧蚀膀胱的内壁。

87. 发明申请

US20070135736A1 Involuntary Contraction Induced Pressure as a Medical Diagnostic Tool 有权
标题翻译：非自愿收缩感应压力作为医疗诊断工具
公开(公告)号：US20070135736A1
公开(公告)日：2007-06-14
申请号：US11608316
申请日：2006-12-08
申请人： W. Addington , Robert Stephens
发明人： W. Addington , Robert Stephens
IPC分类号： A61B5/117 , A61B5/103 , A61B19/00 , A61B5/00
CPC分类号： A61B5/205 , A61B5/0823 , A61B5/202 , A61B5/6874 , A61B2017/00805
摘要： Techniques for detecting stress urinary incontinence use a pressure sensing catheter the electrical indications of which are applied to a processing unit for detecting pressure levels generated during involuntary coughs. The involuntary coughs are induced preferentially by using a nebulized composition of L-tartrate in a pharmaceutically acceptable carrier. The area under the curve generated from pressure samples is calculated and used in conjunction with the detection of urine leakage to determine the existence of stress urinary incontinence.
摘要翻译：用于检测压力性尿失禁的技术使用压力感测导管，其电指示被应用于用于检测在非自愿咳嗽期间产生的压力水平的处理单元。通过在药学上可接受的载体中使用L-酒石酸盐雾化组合物来优先诱导非自愿咳嗽。计算由压力样本产生的曲线下面积，并结合尿液渗漏检测结果确定压力性尿失禁的存在。

88. 发明申请

US20050177067A1 System and method for urodynamic evaluation utilizing micro-electronic mechanical system 审中-公开
标题翻译：使用微电子机械系统进行尿动力学评估的系统和方法
公开(公告)号：US20050177067A1
公开(公告)日：2005-08-11
申请号：US11043830
申请日：2005-01-26
申请人： Michael Tracey , Anthony DiUbaldi
发明人： Michael Tracey , Anthony DiUbaldi
IPC分类号： A61B5/03 , A61B5/20 , A61N1/36 , A61B5/00
CPC分类号： A61N1/36017 , A61B5/14507 , A61B5/202 , A61B5/205 , A61B5/208 , A61B5/6874 , A61B2562/028 , A61N1/36007
摘要： An implantable urodynamic system is provided one embodiment of which includes a power source, at least one sensor for sensing at least one physiological property, a data transmission device for transmitting data representing the at least one sensed physiological property to an exterior of the patient's bladder, and a collapsible housing containing the power source and the at least one sensor therein. The collapsible housing has a collapsed configuration sized for insertion through the patient's urethra and into the patient's bladder, and an expanded configuration sized to remain within the bladder, but be unable to pass from the bladder into the urethra.
摘要翻译：可植入尿动力系统的一个实施例包括电源，用于感测至少一个生理特性的至少一个传感器，用于将表示至少一个感测到的生理特性的数据发送到患者膀胱的外部的数据传输装置，以及容纳所述电源和所述至少一个传感器的可折叠壳体。可折叠壳体具有尺寸适于插入穿过患者尿道并进入患者膀胱的塌缩构造，以及尺寸设计成保持在膀胱内但不能从膀胱穿入尿道的扩张构型。

89. 发明申请

US20030100930A1 Pelvic disorder treatment device 有权
标题翻译：骨盆障碍治疗装置
公开(公告)号：US20030100930A1
公开(公告)日：2003-05-29
申请号：US09996668
申请日：2001-11-29
申请人： BIOCONTROL MEDICAL LTD.
发明人： Ehud Cohen , Yossi Gross , Israel Nissenkorn
IPC分类号： A61N001/18
CPC分类号： A61B5/6874 , A61B5/0031 , A61B5/0215 , A61B5/0488 , A61B5/145 , A61B5/202 , A61B5/204 , A61B5/205 , A61B5/227 , A61B5/4047 , A61B8/12 , A61B8/4472 , A61B2560/0209 , A61B2562/0219 , A61N1/36007
摘要： A device for treating a medical condition is provided, and a surgical procedure for implanting the device is disclosed. The device includes a sensor, which is adapted to generate a signal responsive to a state of a patient, and at least one electrode, which is adapted to be coupled to a pelvic site of the patient. A control unit is adapted to receive the signal, to analyze the signal so as to distinguish between an imminent stress incontinence event and an imminent urge event, and, responsive to analyzing the signal, to apply an electrical waveform to the at least one electrode. In various configurations, the device may be used alternatively or additionally to treat fecal incontinence, interstitial cystitis, chronic pelvic pain, or urine retention.
摘要翻译：提供了用于治疗医疗状况的装置，并且公开了用于植入该装置的外科手术。所述装置包括适于产生响应于患者状态的信号的传感器，以及适于联接到患者的骨盆部位的至少一个电极。控制单元适于接收信号，分析信号以便区分即将发生的压力性尿失禁事件和迫在眉睫的事件，并且响应于分析信号，将电波形施加到至少一个电极。在各种构造中，该装置可以替代地或另外地用于治疗大便失禁，间质性膀胱炎，慢性盆腔疼痛或尿潴留。

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