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1. 发明授权

US11786158B2 Devices and methods for sensing bladder fullness 有权
公开(公告)号：US11786158B2
公开(公告)日：2023-10-17
申请号：US16231331
申请日：2018-12-21
申请人： InCube Labs, LLC
发明人： Ralph Walter Peterson , Kyle Horlen , Stephen R. Kraus , Paul Spehr , Elmar Fischer , Varghese George , Mir A. Imran
IPC分类号： A61B5/20 , A61B5/00 , A61B5/391
CPC分类号： A61B5/204 , A61B5/0059 , A61B5/0075 , A61B5/205 , A61B5/391 , A61B5/6837 , A61B5/6874 , A61B5/486 , A61B5/7282 , A61B5/742
摘要： A bladder fullness monitoring systems includes a controller and an active optical sensor that is affixed to a patient's bladder. The sensor emits light onto the bladder and further detects light reflected from the bladder, in order to generate an output signal that indicates an amount of emitted light was reflected back to the detector. The controller is coupled to the optical sensor to receive and interpret the output signals, e.g., to determine when the bladder is full. The controller may be operatively coupled to a urinary control apparatus which uses the output signals to trigger urination in patients who have lost the ability to voluntarily urinate. Embodiments are particularly useful for monitoring bladder fullness in patients who have lost bladder sensation and/or the ability to voluntary urinate and rely on a urinary control apparatus in order to urinate.

2. 发明申请

US20170224266A1 URINE SENSING OPTICAL FIBER PROBE AND SYSTEM FOR PERCUTANEOUS NEPHROSTOMY 审中-公开
公开(公告)号：US20170224266A1
公开(公告)日：2017-08-10
申请号：US15501140
申请日：2015-08-07
申请人： TELEFLEX MEDICAL INCORPORATED
发明人： JOHN C. VICTOR , MICHAEL J. MORRIS , MAHMOUD R. SHAHRIARI
IPC分类号： A61B5/20 , A61B10/00 , A61B5/00
CPC分类号： A61B5/207 , A61B5/0071 , A61B5/0084 , A61B5/20 , A61B5/201 , A61B5/202 , A61B5/6848 , A61B5/6874 , A61B10/007
摘要： The present application describes a urine sensing probe and a system for detecting urine. The urine sensing probe includes a needle having a tubular portion and one or more optical fibers positioned within the needle. The one or more optical fibers have a distal surface that is oriented towards a beveled distal section of the needle and is oriented to one of its lateral sides. The distal surface of the one or more optical fibers ranges from about 90 to a critical angle with respect to a vertical axis of the needle. The present application also describes a system for sensing urine including a urine sensing probe.

3. 发明申请

US20150328475A1 BIOFEEDBACK APPARATUS USING MAGNETIC STIMULATOR AND CONTROL METHOD THEREFOR 有权
标题翻译：使用磁力刺激仪的生物安全装置及其控制方法
公开(公告)号：US20150328475A1
公开(公告)日：2015-11-19
申请号：US14652603
申请日：2013-08-23
申请人： MCUBETECHNOLOGY CO., LTD.
发明人： Jung Hoe KIM , Seung Tai KIM
IPC分类号： A61N2/00 , A61B5/00 , A61B5/20
CPC分类号： A61N2/004 , A61B5/202 , A61B5/205 , A61B5/227 , A61B5/486 , A61B5/6874 , A61N2/00
摘要： Provided is a biofeedback apparatus using a magnetic stimulator. In the biofeedback apparatus, a tube filled with a non-conductive fluid is disposed between a magnetic stimulator and patient's pelvic floor muscles to measure a change in pressure according to muscle exercise of the pelvic floor muscles, biofeedback is available without insertion of a tool for measurement of a pressure or an EMG (electromyogram) into vagina, urethra, or the like. In the biofeedback apparatus, since driving of the magnetic stimulator and driving of a pressure transducer do not influence each other, a controller can continuously monitor a state of change in pressure of the pelvic floor muscles by using the pressure transducer and, at the same time, can adjust a strength of a magnetic field generated from the magnetic stimulator to an optimal strength according to the monitored state, so that it is possible to maximize the effect of treatment.
摘要翻译：提供了使用磁刺激器的生物反馈装置。在生物反馈装置中，填充有非导电流体的管设置在磁刺激器和患者的盆底肌肉之间，以根据骨盆肌肉的肌肉运动来测量压力变化，生物反馈可用于不插入工具将压力或EMG（肌电图）测量到阴道，尿道等中。在生物反馈装置中，由于磁刺激器的驱动和压力传感器的驱动不会相互影响，因此控制器可以通过使用压力传感器来连续地监测骨盆底肌肉的压力变化的状态，同时，可以根据监视状态将从磁刺激器产生的磁场的强度调整到最佳强度，从而可以使治疗效果最大化。

4. 发明申请

US20110313244A1 GASTROSCOPE 审中-公开
标题翻译：胃肠道
公开(公告)号：US20110313244A1
公开(公告)日：2011-12-22
申请号：US13148615
申请日：2010-02-15
申请人： Stefan Förtsch , Rainer Kuth , Karl-Heinz Maier
发明人： Stefan Förtsch , Rainer Kuth , Karl-Heinz Maier
IPC分类号： A61B1/00
CPC分类号： A61B5/053 , A61B1/018 , A61B1/2736 , A61B5/14507 , A61B5/14546 , A61B5/4238 , A61B5/6851 , A61B5/6874 , A61B2018/126 , A61B2562/0215
摘要： A gastroscope has an insertion tube with a working channel therein, and a sensor is guided in the working channel via a guidewire. The sensor has a first electrode produced of an acid-resistant noble metal, and a second electrode produced of silver. An electrical voltage is applied between the first and second electrodes, and a change in an electrical variable is measured between the first and second electrodes when ammonia is present. The gastroscope allows screening of gastric acid and tissue in the stomach lining for Helicobacter pylori in a manner that is gentle for the patient.
摘要翻译：胃镜具有其中具有工作通道的插入管，并且传感器通过导丝在工作通道中被引导。传感器具有由耐酸性贵金属制成的第一电极和由银制成的第二电极。在第一和第二电极之间施加电压，并且当存在氨时，在第一和第二电极之间测量电变量的变化。胃镜允许以对患者温和的方式筛选幽门螺杆菌胃内衬里的胃酸和组织。

5. 发明申请

US20110264163A1 System and Method for Nerve Stimulation 有权
标题翻译：神经刺激的系统和方法
公开(公告)号：US20110264163A1
公开(公告)日：2011-10-27
申请号：US13094644
申请日：2011-04-26
申请人： Michael R. Tracey , Anthony DiUbaldi
发明人： Michael R. Tracey , Anthony DiUbaldi
IPC分类号： A61N1/36
CPC分类号： A61N1/36007 , A61B5/20 , A61B5/202 , A61B5/205 , A61B5/6874 , A61B2562/028 , A61N1/0492 , A61N1/0514 , A61N1/0521 , A61N1/36017 , A61N1/36021 , G06F19/00
摘要： A system and method for stimulating a nerve, wherein the system includes a first waveform generator adapted to generate a first waveform having a frequency capable of stimulating a predetermined nerve of the mammal, a second waveform generator adapted to generate a carrier waveform having a frequency capable of passing through tissue of the mammal, a modulation device electrically coupled to the first and second waveform generators and adapted to modulate the first and carrier waveforms to create a modulated waveform, and an electrode electrically coupled to the modulation device and positioned substantially adjacent to skin of the mammal, and adapted to apply the modulated waveform thereto.
摘要翻译：一种用于刺激神经的系统和方法，其中所述系统包括适于产生具有能够刺激哺乳动物的预定神经的频率的第一波形的第一波形发生器，适于生成具有频率能力的载波波形的第二波形发生器通过哺乳动物的组织的调制装置，电耦合到第一和第二波形发生器并适于调制第一和载波波形以产生调制波形的调制装置，以及电耦合到调制装置并基本上邻近皮肤定位的电极并且适于将调制波形应用于其。

6. 发明授权

US07911315B2 Miniature pressure sensor assembly for catheter 有权
标题翻译：用于导管的微型压力传感器组件
公开(公告)号：US07911315B2
公开(公告)日：2011-03-22
申请号：US11496533
申请日：2006-07-28
申请人： Alistair D. Bradley
发明人： Alistair D. Bradley
IPC分类号： A61B5/103 , A61B5/117 , G01B5/30 , G01B7/16 , H01L27/108 , H01L29/94 , G01L1/22 , H01C10/10
CPC分类号： A61B5/0215 , A61B5/03 , A61B5/6874 , A61B2562/028 , A61M2025/0002
摘要： A pressure sensor assembly configured for use with a catheter. In one illustrative embodiment, the pressure sensor assembly may include a multi-layer co-fired ceramic (MLCC) package. The MLCC package may include two or more ceramic layers that are co-fired together, with a cavity defined by at least some of the ceramic layers. At least one internal bond pad is provided within the cavity, and at least one external connection point is provided on the MLCC package exterior. A sensor, such as a pressure sensor, may be positioned and attached within the cavity. The sensor may be electrically connected to at least one of the internal bond pads. In some cases, a sealant may be used to encapsulate the sensor within the cavity. Once fabricated, the MLCC sensor assembly may be provided in a sensor lumen of a catheter.
摘要翻译：构造成与导管一起使用的压力传感器组件。在一个说明性实施例中，压力传感器组件可以包括多层共烧陶瓷（MLCC）封装。 MLCC封装可以包括两个或更多个共同烧结的陶瓷层，其中空腔由至少一些陶瓷层限定。在空腔内设置至少一个内部接合焊盘，并且至少一个外部连接点设置在MLCC封装外部。诸如压力传感器的传感器可以被定位并附接在空腔内。传感器可以电连接到至少一个内部接合焊盘。在一些情况下，可以使用密封剂将传感器封装在空腔内。一旦制造，MLCC传感器组件可以设置在导管的传感器腔中。

7. 发明申请

US20100228157A1 Tensiometer Utilizing Elastic Conductors 有权
标题翻译：利用弹性导体的张力计
公开(公告)号：US20100228157A1
公开(公告)日：2010-09-09
申请号：US12720428
申请日：2010-03-09
申请人： Michael D. Tom
发明人： Michael D. Tom
IPC分类号： A61B5/103
CPC分类号： A61B5/036 , A61B5/1076 , A61B5/4519 , A61B5/6874 , A61B2562/0247 , Y10T428/27
摘要： A tensiometer is an elastic conductor which comprises a mixture of an elastomer and carbon nanotubes. The tensiometer has a reproducible conductivity in order to measure and change in shape and tension of an object to which it is applied. The tensiometer is non-toxic and may be implanted into a human body.
摘要翻译：张力计是包含弹性体和碳纳米管的混合物的弹性导体。张力计具有可再现的导电性，以便测量并改变其所施加的物体的形状和张力。张力计无毒，可植入人体内。

8. 发明申请

US20070255090A1 Techniques for Evaluating Urinary Stress Incontinence 有权
标题翻译：评估尿失禁的技术
公开(公告)号：US20070255090A1
公开(公告)日：2007-11-01
申请号：US11550125
申请日：2006-10-17
申请人： W. Addington , Stuart Miller , Robert Stephens
发明人： W. Addington , Stuart Miller , Robert Stephens
IPC分类号： A61F2/00
CPC分类号： A61B5/202 , A61B5/205 , A61B5/6874
摘要： Techniques for detecting stress urinary incontinence use a pressure sensing catheter the electrical indications of which are applied to a processing unit for detecting pressure levels generated during involuntary coughs. The involuntary coughs are induced preferentially by using a nebulized composition of L-tartrate in a pharmaceutically acceptable carrier. The area under the curve generated from pressure samples is calculated and used in conjunction with the detection of urine leakage to determine the existence of stress urinary incontinence.
摘要翻译：用于检测压力性尿失禁的技术使用压力感测导管，其电指示被应用于用于检测在非自愿咳嗽期间产生的压力水平的处理单元。通过在药学上可接受的载体中使用L-酒石酸盐雾化组合物来优先诱导非自愿咳嗽。计算由压力样本产生的曲线下面积，并结合尿液渗漏检测结果确定压力性尿失禁的存在。

9. 发明申请

US20070010737A1 Method for simulation of an electric stimulation in an mr imaging system 失效
标题翻译：用于模拟mr成像系统中电刺激的方法
公开(公告)号：US20070010737A1
公开(公告)日：2007-01-11
申请号：US10554339
申请日：2004-04-22
申请人： Paul Harvey , Jouke Smink , Gerardus Peeren , Jacob Den Boer
发明人： Paul Harvey , Jouke Smink , Gerardus Peeren , Jacob Den Boer
IPC分类号： A61B5/05
CPC分类号： A61B5/055 , A61B5/6874 , A61B5/7239 , A61N2/02
摘要： A novel method is described for simulation of an electric stimulation of the nerve system subject to the rate of change of gradient fields. A gradient signal is filtered and a stimulation signal is derived, which is compared with a predetermined stimulation threshold value. An indicator signal is generated if the threshold value is exceeded. Therefore the time dependent and spatially dependent electric fields as defined by the scanning sequence and the gradient coil properties are calculated. A vector combination of said calculated electric field components from each gradient coil axis is performed, which results in a temporal diagram of the total electric field at various spatial locations within the gradient coil. The stimulation probability at each location from said temporal diagram and said stimulation signal is then calculated, and said stimulation probability is compared with the stimulation threshold value at each location within the gradient coil.
摘要翻译：描述了一种新颖的方法来模拟经过梯度场变化率的神经系统的电刺激。对梯度信号进行滤波，得到与预定的刺激阈值进行比较的刺激信号。如果超过阈值，则产生指示信号。因此，计算由扫描序列和梯度线圈特性定义的时间依赖性和空间依赖性电场。执行来自每个梯度线圈轴的所述计算的电场分量的矢量组合，其导致梯度线圈内的各个空间位置处的总电场的时间图。然后计算来自所述时间图和所述刺激信号的每个位置处的刺激概率，并将所述刺激概率与梯度线圈内的每个位置处的刺激阈值进行比较。

10. 发明申请

US20060020225A1 Wireless urodynamic monitoring system with automated voiding diary 审中-公开
标题翻译：无线尿动力监测系统，具有自动排尿日记
公开(公告)号：US20060020225A1
公开(公告)日：2006-01-26
申请号：US10978233
申请日：2004-10-29
申请人： Martin Gerber , William Weimer
发明人： Martin Gerber , William Weimer
IPC分类号： A61B5/00
CPC分类号： A61B5/14539 , A61B5/002 , A61B5/0022 , A61B5/202 , A61B5/204 , A61B5/205 , A61B5/208 , A61B5/6874 , G16H40/67
摘要： The disclosure describes a wireless urodynamic monitoring system with an automated voiding diary feature. The system senses and records urodynamic information in response to a user command or in response to detection of the onset of a voiding event. The urodynamic information obtained over a series of voiding events forms an automated voiding diary that is useful in diagnosis of urological disorders. An implantable monitor obtains the urodynamic information and either records the information locally or transmits the information to an external controller via a wireless telemetry link. In some embodiments, the external controller may include a loop recorder for recording urodynamic information obtained by the implantable monitor over an extended period of time.
摘要翻译：本公开描述了具有自动排尿日记特征的无线尿动力监测系统。该系统响应于用户命令或响应于检测到排尿事件的发作而感测并记录尿动力学信息。通过一系列排尿事件获得的尿动力学信息形成了可用于诊断泌尿系统疾病的自动化排尿日记。可植入式监视器获取尿动力学信息，并在本地记录信息，或通过无线遥测链路将信息传输到外部控制器。在一些实施例中，外部控制器可以包括循环记录器，用于在延长的时间段内记录由可植入监视器获得的尿动力学信息。

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