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81. 发明授权

US07472838B2 Fluid injection valve 有权
标题翻译：流体注射阀
公开(公告)号：US07472838B2
公开(公告)日：2009-01-06
申请号：US11258288
申请日：2005-10-26
申请人： Hidekazu Omura , Yoshinori Yamashita , Yukio Tomiita , Yukio Sawada
发明人： Hidekazu Omura , Yoshinori Yamashita , Yukio Tomiita , Yukio Sawada
IPC分类号： F02M47/02 , F02M61/00
CPC分类号： F02M61/1853
摘要： A fluid injection valve has: a valve body that is provided with an opening portion at one axial end thereof and is for starting and stopping a supply of a fluid out of the opening portion; and an injection port plate having a plurality of injection ports that penetrate therethrough, the injection port plate being fixed on the one axial end of the valve body to form a fluid chamber between itself and the valve body to accumulate the fluid therein and to which at least a part of the injection ports opens. A circumferential surface of the fluid chamber recedes toward the injection ports so as to decrease a cross-sectional area of the fluid chamber that is taken along a radial direction of the injection port plate and to reserve a predetermined length of distance between itself and the injection ports.
摘要翻译：流体喷射阀具有：阀体，其在其一个轴向端部设置有开口部，并且用于启动和停止从所述开口部分流出的流体; 以及具有贯穿其中的多个注入口的注入口板，所述注入口板固定在所述阀体的一个轴向端部上，以在其本身和所述阀体之间形成流体室，以将流体积聚在其中，至少一部分注入口打开。流体室的圆周表面朝向喷射口退出，以减小流体室的沿着喷射孔板的径向截取的横截面面积，并且在其自身与喷射之间保留预定长度的距离港口。

82. 发明授权

US07425636B2 Thiadiazoline derivative 有权
标题翻译：噻二唑啉衍生物
公开(公告)号：US07425636B2
公开(公告)日：2008-09-16
申请号：US10497531
申请日：2002-12-11
申请人： Chikara Murakata , Kazuhiko Kato , Yoshihisa Ohta , Ryuichiro Nakai , Yoshinori Yamashita , Takeshi Takahashi
发明人： Chikara Murakata , Kazuhiko Kato , Yoshihisa Ohta , Ryuichiro Nakai , Yoshinori Yamashita , Takeshi Takahashi
IPC分类号： C07D285/135 , A61K31/433
CPC分类号： C07D285/135 , A61K31/433 , A61K31/4439 , A61K31/497 , A61K31/5377
摘要： (wherein R1 and R4 are the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkynyl, substituted or unsubstituted lower alkenyl, or the like; R5 represents a substituted or unsubstituted heterocyclic group, substituted or unsubstituted aryl, or the like; R2 represents —C(═W)R6 or the like; R3 represents a hydrogen atom, —C(═WA)R6A, or the like) Antitumor agents which comprises a thiadiazoline derivative represented by the aforementioned general formula (I) or a pharmacologically acceptable salt thereof as an active ingredient are provided.
摘要翻译：（其中R 1和R 4相同或不同，各自表示氢原子，取代或未取代的低级烷基，取代或未取代的低级炔基，取代或未取代的低级链烯基等等; R 5表示取代或未取代的杂环基，取代或未取代的芳基等; R 2表示-C（-W）R SUP > 6个等等; R 3表示氢原子，-C（-W A）SO 6，或者提供包含由上述通式（I）表示的噻二唑啉衍生物或其药理学上可接受的盐作为有效成分的抗肿瘤剂。

83. 发明申请

US20070213380A1 Thiadiazoline derivative 审中-公开
标题翻译：噻二唑啉衍生物
公开(公告)号：US20070213380A1
公开(公告)日：2007-09-13
申请号：US11798214
申请日：2007-05-11
申请人： Chikara Murakata , Kazuhiko Kato , Yoshihisa Ohta , Ryuichiro Nakai , Yoshinori Yamashita , Takeshi Takahashi , Tomohisa Nakano , Yoji Ino
发明人： Chikara Murakata , Kazuhiko Kato , Yoshihisa Ohta , Ryuichiro Nakai , Yoshinori Yamashita , Takeshi Takahashi , Tomohisa Nakano , Yoji Ino
IPC分类号： A61K31/433 , C07D285/135
CPC分类号： C07D285/135 , A61K31/433 , A61K31/4439 , A61K31/497 , A61K31/5377
摘要： (wherein R1 and R4 are the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkynyl, substituted or unsubstituted lower alkenyl, or the like; R5 represents a substituted or unsubstituted heterocyclic group, substituted or unsubstituted aryl, or the like; R2 represents —C(═W)R6 or the like; R3 represents a hydrogen atom, —C(═WA)R6A, or the like) Antitumor agents which comprises a thiadiazoline derivative represented by the aforementioned general formula (I) or a pharmacologically acceptable salt thereof as an active ingredient are provided.
摘要翻译：（其中R 1和R 4相同或不同，各自表示氢原子，取代或未取代的低级烷基，取代或未取代的低级炔基，取代或未取代的低级链烯基等等; R 5表示取代或未取代的杂环基，取代或未取代的芳基等; R 2表示-C（-W）R SUP > 6个等等; R 3表示氢原子，-C（-W A）SO 6，或者提供包含由上述通式（I）表示的噻二唑啉衍生物或其药理学上可接受的盐作为有效成分的抗肿瘤剂。

84. 发明申请

US20060086830A1 Fluid injection valve 有权
公开(公告)号：US20060086830A1
公开(公告)日：2006-04-27
申请号：US11258288
申请日：2005-10-26
申请人： Hidekazu Omura , Yoshinori Yamashita , Yukio Tomiita , Yukio Sawada
发明人： Hidekazu Omura , Yoshinori Yamashita , Yukio Tomiita , Yukio Sawada
IPC分类号： F02M61/00
CPC分类号： F02M61/1853
摘要： A fluid injection valve has: a valve body that is provided with an opening portion at one axial end thereof and is for starting and stopping a supply of a fluid out of the opening portion; and an injection port plate having a plurality of injection ports that penetrate therethrough, the injection port plate being fixed on the one axial end of the valve body to form a fluid chamber between itself and the valve body to accumulate the fluid therein and to which at least a part of the injection ports opens. A circumferential surface of the fluid chamber recedes toward the injection ports so as to decrease a cross-sectional area of the fluid chamber that is taken along a radial direction of the injection port plate and to reserve a predetermined length of distance between itself and the injection ports.

85. 发明申请

US20060074113A1 Thiadiazoline derivative 有权
标题翻译：噻二唑啉衍生物
公开(公告)号：US20060074113A1
公开(公告)日：2006-04-06
申请号：US10497531
申请日：2002-12-11
申请人： Chikara Murakata , Kazuhiko Kato , Yoshihisa Ohta , Ryuichiro Nakai , Yoshinori Yamashita , Takeshi Takahashi , Tomohisa Nakano , Yoji Ino
发明人： Chikara Murakata , Kazuhiko Kato , Yoshihisa Ohta , Ryuichiro Nakai , Yoshinori Yamashita , Takeshi Takahashi , Tomohisa Nakano , Yoji Ino
IPC分类号： A61K31/433 , C07D285/12
CPC分类号： C07D285/135 , A61K31/433 , A61K31/4439 , A61K31/497 , A61K31/5377
摘要： (wherein R1 and R4 are the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkynyl, substituted or unsubstituted lower alkenyl, or the like; R5 represents a substituted or unsubstituted heterocyclic group, substituted or unsubstituted aryl, or the like; R2 represents —C(═W)R6 or the like; R3 represents a hydrogen atom, —C(═WA)R6A, or the like) Antitumor agents which comprises a thiadiazoline derivative represented by the aforementioned general formula (I) or a pharmacologically acceptable salt thereof as an active ingredient are provided.
摘要翻译：（其中R 1和R 4相同或不同，各自表示氢原子，取代或未取代的低级烷基，取代或未取代的低级炔基，取代或未取代的低级链烯基等等; R 5表示取代或未取代的杂环基，取代或未取代的芳基等; R 2表示-C（-W）R SUP > 6个等等; R 3表示氢原子，-C（-W A）SO 6，或者提供包含由上述通式（I）表示的噻二唑啉衍生物或其药理学上可接受的盐作为有效成分的抗肿瘤剂。

86. 发明授权

US06487431B1 Radiographic apparatus and method for monitoring the path of a thrust needle 有权
标题翻译：用于监测推力针的路径的射线照相装置和方法
公开(公告)号：US06487431B1
公开(公告)日：2002-11-26
申请号：US09396436
申请日：1999-09-15
申请人： Teruaki Iwano , Yoshinori Yamashita , Takashi Marume
发明人： Teruaki Iwano , Yoshinori Yamashita , Takashi Marume
IPC分类号： A61B505
CPC分类号： A61B6/4447 , A61B6/032 , A61B6/12 , A61B10/0233 , A61B90/11
摘要： A radiographic apparatus is disclosed, which allows a biopsy needle or a drug injection needle to be run into a patient accurately and quickly. Once a needle entry point on a body surface of the patient and a target point in the patient are designated and inputted on the screen of a display monitor, the radiographic apparatus in this invention automatically displays, en block on the display monitor, a guideline linking the two points, intersection marks indicative of intersections of the guideline and CT images, and angles and length serving as a reference for determining a direction and depth of running the needle. The operator has only to run the needle to a required depth along the guideline and intersection marks in the direction indicated by the angles displayed. Thus, the biopsy needle or injection needle may be run into the patient accurately and quickly.
摘要翻译：公开了一种放射线照相设备，其允许活检针或药物注射针准确且快速地进入患者。一旦在患者的身体表面上的针入口点和患者中的目标点被指定并输入到显示监视器的屏幕上，本发明的射线照相设备将自动显示在显示监视器上的指南链接两点，指示指纹和CT图像的交点的交叉标记，以及用作确定针的运行方向和深度的参考的角度和长度。操作人员只能沿着指导针将指针运行到所需的深度，并以所显示的角度指示的方向交叉。因此，活检针或注射针可以准确而快速地进入患者。

87. 发明授权

US6165398A Method of slip casting powdery material, using a water resistant mold with self-water absorbent ability 失效
标题翻译：粉状浇注粉的方法，使用具有自吸水能力的防水模具
公开(公告)号：US6165398A
公开(公告)日：2000-12-26
申请号：US32284
申请日：1998-02-26
申请人： Akio Matsumoto , Takeshi Sato , Yoshifumi Misumi , Akira Hirayama , Katsuhiro Hasebe , Yoshinori Yamashita
发明人： Akio Matsumoto , Takeshi Sato , Yoshifumi Misumi , Akira Hirayama , Katsuhiro Hasebe , Yoshinori Yamashita
IPC分类号： B22F3/22 , B28B1/26
CPC分类号： B28B1/26 , B22F3/22 , B28B1/263 , B28B1/265
摘要： A method of slip casting using a casting mold provided with a water-absorbent layer that has a self-water-absorbent ability, substantially has a water resistance, and is controlled in the saturated water content thereof, the slip casting being conducted by employing mainly a capillary sucking force as the driving force of the water-absorbent layer of cast formation. An open-cell porous body usable as the water-absorbent layer is produced by agitating a mixture comprising a compound having at least one epoxy ring in its molecule, a curing agent which cures the epoxy compound by reaction, a filler developing for a self-water-absorbent ability and a mold release property, and water to prepare an O/W emulsion slurry and curing the slurry, as such in a hydrous state.
摘要翻译： PCT No.PCT / JP96 / 02368 Sec。 371日期1999年2月26日 102（e）1999年2月26日PCT PCT 1996年8月26日PCT公布。出版物WO97 / 07948 日期1997年3月6日使用具有吸水层的具有自吸水能力的铸模的滑动铸造方法，基本上具有耐水性，并且控制在其饱和水含量中，通过主要采用毛细管吸力作为铸造吸水层的驱动力来进行。可用作吸水层的开孔多孔体通过搅拌其分子中含有至少一个环氧环的化合物的混合物，通过反应固化环氧化合物的固化剂，吸水能力和脱模性，以及水以制备O / W乳液浆料并使其在含水状态下固化。

88. 发明授权

US5826472A Method and apparatus for processing a wire 失效
标题翻译：线材加工方法及装置
公开(公告)号：US5826472A
公开(公告)日：1998-10-27
申请号：US713238
申请日：1996-09-12
申请人： Yoshikazu Tamura , Yoshinori Yamashita
发明人： Yoshikazu Tamura , Yoshinori Yamashita
IPC分类号： B21F11/00 , B21F23/00 , H01B13/012 , H01R43/28 , B23Q15/20
CPC分类号： H01R43/28 , Y10S83/907 , Y10S83/95 , Y10T83/141 , Y10T83/145 , Y10T83/178 , Y10T83/53 , Y10T83/54
摘要： A wire processing apparatus is provided with a prefeeder 120, a feeding unit 12 and an accumulator 110 therebetween. A detector is provided to determine if there is a cause for stopping the prefeeder 120. In response to such a detected cause, a controller stops the prefeeder 120 while simultaneously permitting the feeding unit 12 to draw a wire from the accumulator to permit continued operation of the wire processing apparatus.
摘要翻译：线加工装置在其间设置有预取器120，进给单元12和累加器110。提供检测器以确定是否存在用于停止预送器120的原因。响应于这种检测原因，控制器停止预送器120，同时允许馈送单元12从蓄电池中抽出电线以允许继续操作线加工装置。

89. 发明授权

US5522717A Mold for pressure-cast-molding a ceramic article formed from an open-cell porous material 失效
标题翻译：用于压铸成型由开孔多孔材料形成的陶瓷制品的模具
公开(公告)号：US5522717A
公开(公告)日：1996-06-04
申请号：US394070
申请日：1995-02-24
申请人： Akio Matsumoto , Shingo Kasahara , Yoshifumi Misumi , Yoshinori Yamashita
发明人： Akio Matsumoto , Shingo Kasahara , Yoshifumi Misumi , Yoshinori Yamashita
IPC分类号： B28B1/26 , B28B7/34 , B29C70/66 , C08J9/28 , C08J9/32
CPC分类号： C08J9/32 , B28B1/263 , B28B7/344 , B29C70/66 , C08J9/28 , B29K2063/00 , B29K2105/165 , B29L2031/757 , C08J2363/00 , Y10S425/119
摘要： A mold for pressure-cast-molding a ceramic article having a filter material made of an open-cell porous material. The open-cell porous material is prepared by stirring a mixture of a resin material, a microballoon, a curing agent and water to provide an emulsion slurry, casting the slurry in a water-impermeable mold and curing the slurry in the water-containing state. The portions occupied by the water during the preparation of the porous material mainly form open pores.
摘要翻译：一种用于压铸铸造具有由开孔多孔材料制成的过滤材料的陶瓷制品的模具。通过搅拌树脂材料，微球，固化剂和水的混合物来制备开孔多孔材料，以提供乳液浆料，将浆料浇注在不透水模具中并使含水状态的浆料固化。在制备多孔材料期间由水占据的部分主要形成开孔。

90. 发明授权

US5366966A Compound UCE6 失效
标题翻译：化合物UCE6
公开(公告)号：US5366966A
公开(公告)日：1994-11-22
申请号：US070962
申请日：1993-06-04
申请人： Hirofumi Nakano , Noboru Fujii , Yoshinori Yamashita , Youichi Uosaki , Shigeru Chiba , Shigeo Katsumata , Yukari Tsuji
发明人： Hirofumi Nakano , Noboru Fujii , Yoshinori Yamashita , Youichi Uosaki , Shigeru Chiba , Shigeo Katsumata , Yukari Tsuji
IPC分类号： A61K31/12 , A61K31/122 , A61P35/00 , C07C50/38 , C12P15/00 , C12R1/01 , C07C15/38
CPC分类号： C12P15/00 , C07C50/38
摘要： A compound represented by formula (I): ##STR1## or a pharmaceutically acceptable salt thereof is provided, which has an excellent antitumor activity.
摘要翻译：提供由式（I）表示的化合物：其具有优异的抗肿瘤活性。

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