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81. 发明申请

US20090262109A1 ILLUSTRATING A THREE-DIMENSIONAL NATURE OF A DATA SET ON A TWO-DIMENSIONAL DISPLAY 有权
标题翻译：说明数据集在三维显示上的三维性质
公开(公告)号：US20090262109A1
公开(公告)日：2009-10-22
申请号：US12423966
申请日：2009-04-15
申请人： H. Toby Markowitz , Sean Campbell-Massa , Phillip Falkner , Ioana Fleming , Chad Giese , Mustafa Karamanoglu , Michael Kryger , Karl Evan Nowak , Pooja Mehta , James Steeves , Lane A. Phillips , Shangqian Peter Zhang , Steven L. Waldhauser , David A. Scanlon , Brian Houston Craig , Eduardo N. Warman , Koen Michels , Marie P. Smith , Noelle Christine Hurtig , Olaf Eick , Rogier Receveur , Vincent Larik , Brent Chelgren , Victoria Interrante
发明人： H. Toby Markowitz , Sean Campbell-Massa , Phillip Falkner , Ioana Fleming , Chad Giese , Mustafa Karamanoglu , Michael Kryger , Karl Evan Nowak , Pooja Mehta , James Steeves , Lane A. Phillips , Shangqian Peter Zhang , Steven L. Waldhauser , David A. Scanlon , Brian Houston Craig , Eduardo N. Warman , Koen Michels , Marie P. Smith , Noelle Christine Hurtig , Olaf Eick , Rogier Receveur , Vincent Larik , Brent Chelgren , Victoria Interrante
IPC分类号： G06T15/00
CPC分类号： G06T19/003 , A61B5/0422 , A61B5/05 , A61B5/053 , A61B5/0538 , A61B5/063 , A61B5/066 , A61B5/068 , A61B8/06 , A61B34/20 , A61B34/25 , A61B2017/00022 , A61B2017/00026 , A61B2017/00053 , A61B2017/00084 , A61B2017/00243 , A61B2017/22051 , A61B2034/102 , A61B2034/105 , A61B2034/2051 , A61B2034/2068 , A61B2034/2072 , A61B2090/061 , A61B2090/063 , A61B2090/371 , A61B2090/376 , A61B2090/378
摘要： A volume of a patient can be mapped with a system operable to identify a plurality of locations and save a plurality of locations of a mapping instrument. The mapping instrument can include one or more electrodes that can sense a voltage that can be correlated to a three dimensional location of the electrode at the time of the sensing or measurement. Therefore, a map of a volume can be determined based upon the sensing of the plurality of points without the use of other imaging devices. An implantable medical device can then be navigated relative to the mapping data.
摘要翻译：可以利用可操作以识别多个位置并且保存映射仪器的多个位置的系统来映射患者体积。映射仪器可以包括一个或多个电极，其可以感测在感测或测量时可以与电极的三维位置相关联的电压。因此，可以基于多个点的感测而不使用其它成像装置来确定体积的映射。然后可以相对于映射数据导航可植入医疗装置。

82. 发明授权

US07103404B2 Detection of tachyarrhythmia termination 有权
标题翻译：检测快速性心律失常终止
公开(公告)号：US07103404B2
公开(公告)日：2006-09-05
申请号：US10375457
申请日：2003-02-27
申请人： Robert W. Stadler , Eduardo N. Warman , James H. Ericksen , Reece W. Holbrook
发明人： Robert W. Stadler , Eduardo N. Warman , James H. Ericksen , Reece W. Holbrook
IPC分类号： A61B5/0452 , A61N1/37
CPC分类号： A61N1/3622
摘要： Determining termination of an identified tachyarrhythmia episode may involve analysis of a relative decrease in tachyarrhythmia rate, a normalization of electrogram morphology criteria, or both. An implanted medical device may obtain a tachyarrhythmia rate and a morphology of a cardiac waveform. The device may compare the tachyarrhythmia rate to a threshold tachyarrhythmia rate and the morphology to a template morphology, and classify the heart beat as indicating termination of the tachyarrhythmia episode when the tachyarrhythmia rate is less than the threshold tachyarrhythmia rate, the morphology categorizes as normal, or both. For arrhythmias with no therapy delivered, observation of arrhythmia behavior at the point of termination may lead to improved classification. In addition, observation of a relative decrease in tachyarrhythmia rate immediately after therapy application can lead to application of slower but more specific criteria for redetection. Also, delivery of cardioversion shocks can be aborted upon tachyarrhythmia termination.
摘要翻译：确定确定的快速性心律失常发作的终止可能涉及快速心律失常率相对降低的分析，电描记图形态学标准的归一化或两者。植入的医疗装置可以获得心律失常速率和心脏波形的形态。该装置可以将快速性心律失常率与阈值快速性心律失常率和形态学比较为模板形态，并且当心律失常发生率低于阈值快速性心律失常率时，将心跳分类为指示快速性心律失常发作的终止，形态分类为正常，或两者。对于没有治疗的心律失常，在终止时观察心律失常行为可能导致分类改善。另外，在治疗后立即观察到快速性心律失常发生率的相对降低可导致应用较慢但更具体的重新检测标准。此外，快速性心律失常终止时，心脏复律冲击的输送可以中止。

83. 发明授权

US07029470B2 Ablation system and method of use 有权
标题翻译：消融系统和使用方法
公开(公告)号：US07029470B2
公开(公告)日：2006-04-18
申请号：US10685236
申请日：2003-10-14
申请人： David E. Francischelli , Eduardo N. Warman , Rahul Mehra , Mark T. Stewart , James R. Skarda , Harry Puryear , David Schwartzman
发明人： David E. Francischelli , Eduardo N. Warman , Rahul Mehra , Mark T. Stewart , James R. Skarda , Harry Puryear , David Schwartzman
IPC分类号： A61B18/18 , A61B5/02 , A61N1/00
CPC分类号： A61B18/1445 , A61B5/04 , A61B18/12 , A61B2018/00065 , A61B2018/00363 , A61B2018/00577 , A61B2018/00654 , A61B2018/00702 , A61B2018/00755 , A61B2018/00779 , A61B2018/00791 , A61B2018/00839 , A61B2018/00875 , A61B2018/1226 , A61B2018/1253 , A61B2018/126 , A61B2018/1467 , A61B2018/1472 , A61B2218/002 , A61N1/403
摘要： A system and method for creating lesions and assessing their completeness or transmurality. Assessment of transmurality of a lesion is accomplished by monitoring the depolarization signal in a local electrogram taken using electrodes located adjacent the tissue to be ablated. Following onset of application of ablation energy to heart tissue, the local electrogram is measured with electrodes located adjacent tissue to be ablated so that the ablation energy to ablation elements can be selectively reduced or terminated when transmurality is detected.
摘要翻译：用于创建病变并评估其完整性或透视性的系统和方法。病变透壁度的评估是通过使用邻近待消融组织的电极拍摄的局部电描记图来监测去极化信号来实现的。在开始将消融能量施加到心脏组织之后，用邻近待组织的组织的电极测量局部电描记图，以便当检测到透视时，消融元件的消融能量可被选择性地减少或终止。

84. 发明授权

US06668195B2 Methods and apparatus for reducing the likelihood of atrial fibrillation 失效
公开(公告)号：US06668195B2
公开(公告)日：2003-12-23
申请号：US10003936
申请日：2001-10-30
申请人： Eduardo N. Warman , H. Toby Markowitz
发明人： Eduardo N. Warman , H. Toby Markowitz
IPC分类号： A61N1362
CPC分类号： A61N1/3622
摘要： Methods and apparatus for reducing the incidence of atrial fibrillation includes selecting a desired ventricular rate, pacing the ventricle of the heart at the desired ventricular rate, and pacing the atrium of the heart at twice the desired ventricular rate while the desired ventricular rate is less than a preferred rate. Some methods of the present invention include pacing the atrium of the heart at the desired ventricular rate while the desired ventricular rate is greater than the preferred rate. Other methods of the present invention include pacing the atrium of the heart at a predetermined/preferred atrial rate while the desired ventricular rate is greater than the preferred rate.

85. 发明授权

US5840079A Method and apparatus for treatment of atrial fibrillation 失效
标题翻译：用于治疗房颤的方法和装置
公开(公告)号：US5840079A
公开(公告)日：1998-11-24
申请号：US827401
申请日：1997-03-27
申请人： Eduardo N. Warman , Luc R. Mongeon
发明人： Eduardo N. Warman , Luc R. Mongeon
IPC分类号： A61N1/362 , A61N1/39
CPC分类号： A61N1/3622
摘要： A method of and apparatus for delivering ventricular pacing pulses to terminate high rate atrial tachyarrhythmias including fibrillation or flutter or to reduce the requirements for termination of atrial fibrillation or flutter. In response to detected atrial fibrillation or flutter, the apparatus delivers ventricular pacing pulses at a lower rate, for example one third or half of the preceding base pacing rate, for a defined, limited period of time. After delivery of the low rate ventricular pacing pulses for the defined time period, if the high rate atrial tachyarrhythmia is not terminated, an additional therapy such a high energy defibrillation pulse or pacing level pulse trains may be applied to the atria. Prior to the delivery of low rate ventricular pacing pulses, the apparatus may deliver a higher rate of ventricular pacing pulses, for example twice the preceding base pacing rate, so that the transition in rates occurring on delivery of the low rate pulses is made more pronounced.
摘要翻译：用于递送心室起搏脉冲以终止高速率心房心律失常的方法和装置，包括原纤维颤动或扑动或减少终止心房颤动或扑动的要求。响应于检测到的心房颤动或颤动，该装置以较低的速率（例如前一个基本起搏速率的三分之一或一半）在限定的有限时间段内递送心室起搏脉冲。在定义的时间段内输送低速率心室起搏脉冲后，如果高速率心房骤停性心律失常未终止，则可以对心房施加额外的治疗，例如高能量除颤脉冲或起搏电平脉冲序列。在递送低速率心室起搏脉冲之前，该装置可以递送更高的心室起搏脉冲速率，例如比之前的基本起搏速率的两倍，使得在低速率脉冲传递时发生的速率的转变更明显。

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