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    • 85. 发明授权
    • Sweetener composition
    • 甜味剂组成
    • US06372279B1
    • 2002-04-16
    • US09707954
    • 2000-11-08
    • Hirotoshi IshidaAkihiro KishishitaTakeshi NagaiKazutaka NagashimaAtsuhiko Hirano
    • Hirotoshi IshidaAkihiro KishishitaTakeshi NagaiKazutaka NagashimaAtsuhiko Hirano
    • A23L1236
    • A23L27/32
    • One embodiment of the present invention provides a sweetener composition, which includes a mixture of N-{N-(3,3-dimethylbutyl)-L-&agr;-aspartyl}-L-phenylalanine 1-methyl ester, and Acesulfame K, wherein a ratio of the Acesulfame K to a total amount of the N-{N-(3,3-dimethylbutyl)-L-&agr;-aspartyl}-L-phenylalanine 1-methyl ester and the Acesulfame K is in the range of 10 to 97% by weight, methods of making and of using. Another embodiment of the present invention provides a method for preparing a sweetener composition, which includes drying an A-type crystal of N-{N-(3,3-dimethylbutyl)-L-&agr;-aspartyl}-L-phenylalanine 1-methyl ester to obtain a C-type crystal of N-{N-(3,3-dimethylbutyl)-L-&agr;-aspartyl}-L-phenylalanine 1-methyl ester. Another embodiment of the present invention provides a method for producing a sweetener, which includes admixing N-{N-(3,3-dimethylbutyl)-L-&agr;-aspartyl}-L-phenylalanine 1-methyl ester with Acesulfame K, wherein a ratio of the Acesulfame K to a total amount of the N-{N-(3,3-dimethylbutyl)-L-&agr;-aspartyl}-L-phenylalanine 1-methyl ester and the Acesulfame K is in the range of 10 to 97% by weight. Another embodiment of the present invention provides a method for improving the dissolution rate of N-{N-(3,3-dimethylbutyl)-L-&agr;-aspartyl}-L-phenylalanine 1-methyl ester, which includes, prior to dissolving the N-{N-(3,3 -dimethylbutyl)-L-&agr;-aspartyl}-L-phenylalanine 1-methyl ester, admixing the N-{N-(3,3-dimethylbutyl)-L-&agr;-aspartyl}-L-phenylalanine 1-methyl ester with Acesulfame K, wherein a ratio of the Acesulfame K to a total amount of the N-{N-(3,3-dimethylbutyl)-L-&agr;-aspartyl}-L-phenylalanine 1-methyl ester and the Acesulfame K is in the range of 10 to 97% by weight.
    • 本发明的一个实施方案提供一种甜味剂组合物,其包括N- {N-(3,3-二甲基丁基)-L-α-天冬氨酰基} -L-苯丙氨酸1-甲酯和乙酰磺胺酸K的混合物,其中a 乙酰磺胺酸钾与N- {N-(3,3-二甲基丁基)-L-α-天冬氨酰基} -L-苯丙氨酸1-甲酯和乙酰磺胺酸钾的总量的比例在10至97的范围内 重量%,制造方法和使用方法。 本发明的另一个实施方案提供了一种制备甜味剂组合物的方法,其包括将N- {N-(3,3-二甲基丁基)-L-α-天冬氨酰基} -L-苯丙氨酸1-甲基 得到N- {N-(3,3-二甲基丁基)-L-α-天冬氨酰基} -L-苯丙氨酸1-甲酯的C型晶体。 本发明的另一个实施方案提供了一种生产甜味剂的方法,其包括将N- {N-(3,3-二甲基丁基)-L-α-天冬氨酰基} -L-苯丙氨酸1-甲酯与乙酰磺胺酸K混合,其中 乙酰磺胺酸钾与N- {N-(3,3-二甲基丁基)-L-α-天冬氨酰基} -L-苯丙氨酸1-甲酯和乙酰磺胺酸钾的总量的比例在10至97的范围内 重量%。 本发明的另一个实施方案提供了一种改善N- {N-(3,3-二甲基丁基)-L-α-天冬氨酰基} -L-苯丙氨酸1-甲酯的溶解速率的方法,其包括在溶解 N- {N-(3,3-二甲基丁基)-L-α-天冬氨酰基} -L-苯丙氨酸1-甲酯,混合N- {N-(3,3-二甲基丁基)-L-α-天冬氨酰基} L-苯丙氨酸1-甲酯与乙酰磺胺酸K,其中乙酰磺胺酸钾与N- {N-(3,3-二甲基丁基)-L-α-天冬氨酰基} -L-苯丙氨酸1-甲基酯的总量的比例 酯和丁磺克烷K的重量百分比在10至97%的范围内。