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81. 发明授权

US06814712B1 Medical probe device and method 失效
标题翻译：医用探针装置及方法
公开(公告)号：US06814712B1
公开(公告)日：2004-11-09
申请号：US08723588
申请日：1996-10-01
申请人： Stuart D. Edwards , Ronald G. Lax , Ingemar H. Lundquist , Hugh R. Sharkey
发明人： Stuart D. Edwards , Ronald G. Lax , Ingemar H. Lundquist , Hugh R. Sharkey
IPC分类号： A61B1720
CPC分类号： A61N5/02 , A61B10/02 , A61B10/0241 , A61B18/00 , A61B18/082 , A61B18/1206 , A61B18/1477 , A61B18/148 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1412 , A61B2018/1425 , A61B2018/1861 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61F2007/0054 , A61M3/0279 , A61M25/0068 , A61M25/0069 , A61M25/008 , A61M25/0082 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/04 , A61N5/045
摘要： A medical probe device comprises a catheter having a stylet guide housing with one or more stylet ports in a side wall thereof and a stylet guide for directing a flexible stylet outward through the stylet port and through intervening tissue at a preselected, adjustable angle to a target tissue. The total catheter assembly includes a stylet guide lumen communicating with the stylet port and a stylet positioned in said stylet guide lumen for longitudinal movement from the port through intervening tissue to a target tissue. The stylet can be an electrical conductor enclosed within a non-conductive layer, the electrical conductor being a radiofrequency electrode. Preferably, the non-conductive layer is a sleeve which is axially moveable on the electrical conductor to expose a selected portion of the electrical conductor surface in the target tissue. The stylet can also be a microwave antenna. The stylet can also be a hollow tube for delivering treatment fluid to the target tissue. It can also include a fiber optic cable for laser treatment. The catheter can include one or more inflatable balloons located adjacent to the stylet port for anchoring the catheter or dilation. Ultrasound transponders and temperature sensors can be attached to the probe end and/or stylet. The stylet guide can define a stylet path from an axial orientation in the catheter through a curved portion to a lateral orientation at the stylet port.
摘要翻译：医疗探针装置包括导管，其具有在其侧壁中具有一个或多个管心针端口的探针引导壳体和用于将柔性探针向外引导通过探针端口的探针引导件，并且以与预定的可调节角度相对的目标通过介入组织组织。总导管组件包括与通管孔端口连通的探针引导腔和位于所述探针引导腔中的探针，用于从端口到介入组织到目标组织的纵向移动。探针可以是封闭在非导电层内的电导体，电导体是射频电极。优选地，非导电层是可在电导体上轴向移动以暴露目标组织中电导体表面的选定部分的套筒。探针也可以是微波天线。探针也可以是用于将治疗流体输送到靶组织的中空管。它还可以包括用于激光治疗的光纤电缆。导管可以包括一个或多个位于探针端口附近的可充气气囊，用于锚定导管或扩张。超声波转发器和温度传感器可以连接到探针端和/或探针。探针引导件可以从导管中的轴向方向定义探针路径，通过弯曲部分到管心针端口处的横向取向。

82. 发明授权

US06743197B1 Treatment of discrete tissues in respiratory, urinary, circulatory, reproductive and digestive systems 有权
标题翻译：治疗呼吸系统，尿液，循环系统，生殖系统和消化系统中的离散组织
公开(公告)号：US06743197B1
公开(公告)日：2004-06-01
申请号：US09347441
申请日：1999-07-02
申请人： Stuart D. Edwards
发明人： Stuart D. Edwards
IPC分类号： A61M3100
CPC分类号： A61F2/10 , A61B18/1492 , A61B2017/003 , A61B2018/00214 , A61B2018/0022 , A61B2018/00261 , A61B2018/0041 , A61B2018/00416 , A61B2018/00797 , A61B2090/3614 , A61M2025/0293 , A61M2025/105
摘要： A method and system for treating body structures or tissue allows treatment by any of ablation, coating, expansion, plumping, shaping, and shrinking. Treatment sitesinclude any of a sphincter, sinus or orifice. During treatment, electrodes emerge from apertures in a balloon. The balloon with liquid from a circulating bath cools tissue in direct contact with electrodes and immediately adjacent, so that discrete regions are treated, with minimal damage to adjacent structures. Sensors, coupled to electrodes, measure treatment properties such as: temperature, impedance and nervous activity. Measurements are used for: diagnostic assessment, determining treatment parameters, providing nervous stimulation and/or blocking, and feedback for controlling energy delivery. The catheter includes an optical path that can be coupled to external viewing apparatus. Endoscopic methods, including fluoroscopic, fiber optic, or radioscopy allow examining tissue and determining position of electrodes. The catheter includes a suction apparatus used to remove liquids obscuring treatment area and to gently conform treatment area to electrodes.
摘要翻译：用于治疗身体结构或组织的方法和系统允许通过消融，涂覆，膨胀，倾斜，成形和收缩中的任何一种进行治疗。治疗部位包括任何括约肌，窦或孔。在治疗期间，电极从气囊中的孔中出现。具有来自循环浴的液体的球囊冷却与电极直接接触的组织，并且立即相邻，使得离散区域被处理，对相邻结构的损伤最小。耦合到电极的传感器测量处理性能，例如：温度，阻抗和神经活动。测量用于：诊断评估，确定治疗参数，提供神经刺激和/或阻塞，以及用于控制能量传递的反馈。导管包括可与外部观察装置连接的光路。内镜方法，包括荧光镜，光纤或放射检查，可以检查组织和确定电极的位置。导管包括用于去除液体的抽吸装置，使得处理区域变得模糊，并且将处理区域轻轻地适应于电极。

83. 发明授权

US06660002B1 RF treatment apparatus 失效
公开(公告)号：US06660002B1
公开(公告)日：2003-12-09
申请号：US09502430
申请日：2000-02-11
申请人： Stuart D. Edwards , James Baker , Bruno Strul , Ronald G. Lax
发明人： Stuart D. Edwards , James Baker , Bruno Strul , Ronald G. Lax
IPC分类号： A61B1818
CPC分类号： A61B18/1482 , A61B18/1206 , A61B18/14 , A61B18/1402 , A61B18/1477 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B2017/00026 , A61B2017/00084 , A61B2018/00011 , A61B2018/00196 , A61B2018/00452 , A61B2018/00476 , A61B2018/00577 , A61B2018/00642 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00761 , A61B2018/00779 , A61B2018/00791 , A61B2018/00821 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1425 , A61B2018/1435 , A61B2018/162 , A61B2018/1861 , A61B2218/002 , A61M3/0279 , A61M25/007 , A61N5/02 , A61N5/04 , A61N5/045
摘要： An RF treatment apparatus includes a catheter with a catheter lumen. A removable needle electrode is positioned in the catheter lumen in a fixed relationship to the catheter. The needle electrode includes a needle lumen and a needle electrode distal end. A removable introducer is slidably positioned in the needle lumen. The introducer includes an introducer distal end. A first sensor is positioned on a surface of the needle electrode or the insulator. An RF power source is coupled to the needle electrode and a return electrode. An insulator sleeve is slidably positioned around the electrode and includes a second sensor. Resources are associated with the electrodes, sensors as well as the RF power source for maintaining a selected power at the electrode independent of changes in current or voltage.

84. 发明授权

US06482204B1 Method and apparatus for controlled contraction of soft tissue 失效
标题翻译：用于控制软组织收缩的方法和装置
公开(公告)号：US06482204B1
公开(公告)日：2002-11-19
申请号：US08637095
申请日：1996-04-24
申请人： Ronald G. Lax , Gary S. Fanton , Stuart D. Edwards
发明人： Ronald G. Lax , Gary S. Fanton , Stuart D. Edwards
IPC分类号： A61B1818
CPC分类号： A61B18/148 , A61B2018/00023 , A61B2018/00083 , A61B2018/00452 , A61B2018/00702 , A61B2018/00791 , A61B2018/143 , A61B2018/1472 , A61B2018/1497 , A61B2018/1861 , A61N1/40
摘要： An apparatus and method are provided for control contraction of tissue that includes collagen fibers. The apparatus includes a handpiece, and an electrode with an electrode proximal end associated with the handpiece. A distal end of the electrode has a geometry that delivers a controlled amount of energy to the tissue for a desired contraction of the collagen fibers. This is achieved while dissociation and breakdown of the collagen fibers is minimized. The handpiece, with electrode, is adapted to be introduced through an operating cannula in percutaneous applications. Additionally, an operating cannula may be included in the apparatus and be attached to the handpiece. The apparatus and method provides for a desired level of contraction of collagen soft tissue without dissociation or breakdown of collagen fibers.
摘要翻译：提供了一种用于控制包括胶原纤维的组织收缩的装置和方法。该装置包括一个手持件和一个具有与手持件相关的电极近端的电极。电极的远端具有几何形状，其将受控量的能量传递到组织以达到期望的胶原纤维的收缩。这是在胶原纤维的解离和分解最小化的同时实现的。具有电极的手持件适于通过经皮应用中的操作插管引入。此外，操作插管可以包括在设备中并且被附接到手持件。该装置和方法提供胶原软组织的期望水平的收缩，而不会胶原纤维的解离或分解。

85. 发明授权

US06464661B2 Medical probe with stylets 失效
标题翻译：医疗探头与风格
公开(公告)号：US06464661B2
公开(公告)日：2002-10-15
申请号：US09819151
申请日：2001-03-27
申请人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James Allen Baker, Jr.
发明人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James Allen Baker, Jr.
IPC分类号： A61B1720
CPC分类号： A61B10/0233 , A61B1/00188 , A61B10/02 , A61B10/0241 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/14 , A61B18/1477 , A61B18/148 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61K31/465 , A61M3/0279 , A61M25/0032 , A61M25/0045 , A61M25/008 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/04 , A61N5/045
摘要： A medical probe device of this invention comprising a catheter having a control end and a probe end. The probe end includes a stylet guide housing having at least one stylet port and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. A stylet is positioned in at least one of said stylet guide means, the stylet comprising a non-conductive sleeve having a RF electrode lumen and an optional a fluid supply lumen and a temperature sensor lumen therein. At least one portion of an opposed surface of the electrode lumen and the electrode can be spaced apart to define a liquid supply passageway for delivery of medicament liquid. The RF electrode enclosed within the non-conductive sleeve has a distal length optionally having at least one current focusing groove means thereon and a distal tip shaped to focus current crowding on its terminal end, whereby Rf current passing therefrom into surrounding tissue forms a lesion extending outward from the groove and tip. The focusing groove means can be a plurality of annular focusing grooves or a spiral focusing groove thereon.
摘要翻译：本发明的医疗探针装置包括具有控制端和探针端的导管。探针端部包括具有至少一个探针端口和探针引导装置的探针引导壳体，用于将柔性探针向外引导通过至少一个通管孔，并通过介入组织引导到靶组织。探针定位在所述探针引导装置中的至少一个上，所述探针包括具有RF电极腔和可选的流体供应管腔和其中的温度传感器腔的非导电套管。电极腔和电极的相对表面的至少一部分可以间隔开以限定用于输送药液的液体供应通道。封闭在非导电套筒内的RF电极具有任选地在其上具有至少一个电流聚焦槽装置的远端长度，以及形成为将电流拥挤聚焦在其末端上的远端，其中从其进入周围组织的Rf电流形成延伸的病变从凹槽和尖端向外。聚焦槽装置可以是多个环形聚焦槽或其上的螺旋形聚焦槽。

86. 发明授权

US06463331B1 Application of energy and substances in the treatment of uro-genital disorders 有权
标题翻译：能源和物质在泌尿生殖器疾病治疗中的应用
公开(公告)号：US06463331B1
公开(公告)日：2002-10-08
申请号：US09539264
申请日：2000-03-30
申请人： Stuart D. Edwards
发明人： Stuart D. Edwards
IPC分类号： A61B1818
CPC分类号： A61B18/1477 , A61B2018/00553 , A61B2018/143 , A61B2018/1432
摘要： This invention provides a method and system for the curative treatment of female uro-genital disorders. One aspect of the invention is that it allows the gynecologist to coagulate the entire endometrium and upper layers of the myometrium in one short procedure that can be performed in a physician's office or other outpatient setting, using local or regional anesthesia. A second aspect of the invention is that it can be used to tighten the urethral sphincter and bladder outlet.
摘要翻译：本发明提供了一种治疗女性泌尿生殖器疾病的方法和系统。本发明的一个方面是允许妇科医生在使用局部或局部麻醉的医师办公室或其他门诊设置中进行的一个简短的程序中凝固子宫内膜和子宫肌层的整个层。本发明的第二方面是其可用于收紧尿道括约肌和膀胱出口。

87. 发明授权

US6126657A Apparatus for treatment of air way obstructions 失效
标题翻译：用于治疗空气障碍物的装置
公开(公告)号：US6126657A
公开(公告)日：2000-10-03
申请号：US895785
申请日：1997-07-17
申请人： Stuart D. Edwards , Ronald G. Lax
发明人： Stuart D. Edwards , Ronald G. Lax
IPC分类号： A61B17/00 , A61B17/24 , A61B18/00 , A61B18/12 , A61B18/14 , A61B18/18 , A61B18/20 , A61B18/22 , A61M1/00 , A61N1/06 , A61N1/40 , A61N5/04 , A61N1/30
CPC分类号： A61B18/1485 , A61B18/1477 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61N1/06 , A61N1/403 , A61N5/045 , A61B17/24 , A61B18/1402 , A61B18/20 , A61B18/22 , A61B2017/00026 , A61B2017/00084 , A61B2018/00011 , A61B2018/00023 , A61B2018/00101 , A61B2018/00196 , A61B2018/00261 , A61B2018/00636 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00744 , A61B2018/00773 , A61B2018/00791 , A61B2018/00875 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1425 , A61B2018/143 , A61B2018/1475 , A61B2090/3782 , A61M2025/0096 , A61N5/04
摘要： An apparatus that reduces a volume of a selected site in an interior of the tongue includes a handpiece and an energy delivery device at least partially positioned in the interior of the handpiece. The energy delivery device includes an energy delivery surface and is advanceable from the interior of the handpiece into the interior of the tongue. An energy delivery device advancement member is coupled to the energy delivery device and configured to advance the energy delivery device an advancement distance in the interior of the tongue. The advancement distance is sufficient for the energy delivery surface to deliver energy to the selected tissue site and reduce a volume of the selected site without damaging a main branch of the hypoglossal nerve. A cable is coupled to the energy delivery device.
摘要翻译：减少舌头内部的所选位置的体积的装置包括至少部分地定位在手持件内部的手持件和能量输送装置。能量输送装置包括能量输送表面，并且可从手持件的内部前进到舌头的内部。能量递送装置推进构件联接到能量输送装置并且被配置为使能量输送装置推进舌头内部的前进距离。前进距离足以使能量输送表面将能量传递到所选择的组织部位并减少选定部位的体积而不损伤舌下神经的主分支。电缆耦合到能量输送装置。

88. 发明授权

US06102886A Steerable medical probe with stylets 失效
标题翻译：可调式医用探头
公开(公告)号：US06102886A
公开(公告)日：2000-08-15
申请号：US85313
申请日：1998-05-27
申请人： Ingemar H. Lundquist , Stuart D. Edwards
发明人： Ingemar H. Lundquist , Stuart D. Edwards
IPC分类号： A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/01 , A61M25/092 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/20
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/06 , A61B17/3403 , A61B17/3417 , A61B17/3478 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61M25/0136 , A61M25/0138 , A61M25/0147 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/045 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/1492 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00123 , A61B2017/00181 , A61B2017/00194 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00469 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00101 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/378 , A61B2090/3782 , A61B2090/3786 , A61B2090/3925 , A61B2217/005 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/0096 , A61M2025/018 , A61M25/0068 , A61M25/008 , A61M25/0082 , A61M3/0279 , A61N5/04
摘要： A medical probe for the treatment by radio frequency ablation of tissue in a human comprising an elongate probe member having proximal and distal extremities. The elongate probe member has a longitudinal axis and at least one passage extending from the proximal extremity to the distal extremity. A guide cannula is mounted in the at least one passage of the elongate probe member and has proximal and distal extremities with the distal extremity of the guide cannula being in the vicinity of the distal extremity of the elongate probe member. The guide cannula has an opening in the distal extremity and a lumen extending from the proximal extremity to the opening in the distal extremity. A stylet is slidably disposed in the lumen of the guide cannula and includes a radio frequency electrode having a distal portion and a layer of insulating material disposed around the radio frequency so that at least the distal portion is exposed. A handle is coupled to the proximal extremity of the elongate probe member. The distal extremity of he guide cannula has a bendable distal portion. The handle includes a first actuator for causing the distal portion of the guide cannula to bend at an angle to the longitudinal axis so that the opening faces the tissue and a second actuator secured to the stylet for advancing the radio frequency electrode and the layer of insulating material from the opening in the guide cannula into the tissue.
摘要翻译：一种用于通过人体组织射频消融治疗的医用探针，包括具有近端和远端的细长探针部件。细长的探针构件具有纵向轴线和从近端延伸到远端的至少一个通道。引导套管安装在细长探针构件的至少一个通道中并且具有近端和远端四肢，导管的远端末端处于细长探针构件的远端附近。导向套管在远侧末端具有开口，以及从近端延伸到远端末端的开口的内腔。探针可滑动地设置在导管的内腔中，并且包括射频电极，其具有围绕射频设置的远侧部分和绝缘材料层，使得至少远端部分暴露。手柄联接到细长探针构件的近端。导向套管的远端具有可弯曲的远端部分。手柄包括第一致动器，用于使引导套管的远端部分与纵向轴线成一定角度弯曲，使得开口面向组织，并且固定到探针的第二致动器用于推进射频电极和绝缘层材料从引导套管中的开口进入组织。

89. 发明授权

US6053937A Multiple electrode ablation apparatus and method with cooling element 失效
标题翻译：多电极消融装置及方法与冷却元件
公开(公告)号：US6053937A
公开(公告)日：2000-04-25
申请号：US963997
申请日：1997-11-04
申请人： Stuart D. Edwards , Patrick J. Burns , Edward J. Gough , Alan A. Stein
发明人： Stuart D. Edwards , Patrick J. Burns , Edward J. Gough , Alan A. Stein
IPC分类号： A61B17/00 , A61B18/00 , A61B18/14 , A61B18/18 , A61M3/02 , A61M25/00 , A61N1/06 , A61N1/40 , A61N5/04 , A61F7/00
CPC分类号： A61B18/1477 , A61B18/1482 , A61B18/18 , A61B18/1815 , A61N1/06 , A61N1/403 , A61N5/045 , A61B18/1206 , A61B18/14 , A61B18/1402 , A61B18/1485 , A61B18/1492 , A61B2017/00022 , A61B2017/00101 , A61B2018/00011 , A61B2018/00023 , A61B2018/00196 , A61B2018/00273 , A61B2018/00452 , A61B2018/00476 , A61B2018/00577 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00779 , A61B2018/00791 , A61B2018/00797 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1425 , A61B2018/143 , A61B2018/1432 , A61B2018/1435 , A61B2018/1472 , A61B2018/162 , A61B2218/002 , A61M25/007 , A61M3/0279 , A61N5/04
摘要： An ablation apparatus has an introducer including an introducer lumen, a proximal portion and a distal portion. Two or more electrodes are at least partially positionable in the introducer lumen. Each electrode is configured to be advanced from the introducer distal portion in a deployed state into a selected tissue site to define a volumetric ablation volume. A fluid delivery member is positioned on at least a portion of an exterior of one of the electrodes. The fluid delivery member is configured to be coupled to a fluid medium source. A cable is coupled to the electrodes.
摘要翻译：消融装置具有导引器，其包括导引腔，近端部分和远端部分。两个或更多个电极至少部分地可定位在导引腔内。每个电极被构造成在展开状态下从导引器远端部分前进到选定的组织部位以限定体积消融体积。流体输送构件位于电极之一的外部的至少一部分上。流体输送构件被配置为联接到流体介质源。电缆耦合到电极。

90. 发明授权

US6044846A Method to treat esophageal sphincters 失效
标题翻译：食管括约肌治疗方法
公开(公告)号：US6044846A
公开(公告)日：2000-04-04
申请号：US32367
申请日：1998-02-27
申请人： Stuart D. Edwards
发明人： Stuart D. Edwards
IPC分类号： A61B17/00 , A61B17/22 , A61B17/42 , A61B18/00 , A61B18/02 , A61B18/04 , A61B18/12 , A61B18/14 , A61B18/18 , A61F2/958 , A61F7/12 , A61M3/02 , A61M16/04 , A61N1/05 , A61N1/06 , A61N1/08 , A61N1/40 , A61B17/89
CPC分类号： A61B18/00 , A61B18/1206 , A61B18/1477 , A61B18/148 , A61B18/1485 , A61B18/1492 , A61M16/0481 , A61N1/056 , A61N1/06 , A61N1/08 , A61N1/40 , A61B18/18 , A61B18/1815 , A61B2017/00022 , A61B2017/00084 , A61B2017/00106 , A61B2017/003 , A61B2017/00867 , A61B2017/22062 , A61B2017/22072 , A61B2017/4216 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00065 , A61B2018/00077 , A61B2018/00083 , A61B2018/00113 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00494 , A61B2018/00553 , A61B2018/00559 , A61B2018/00577 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00738 , A61B2018/00744 , A61B2018/00755 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00827 , A61B2018/00839 , A61B2018/00869 , A61B2018/00875 , A61B2018/00886 , A61B2018/00892 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/00982 , A61B2018/0212 , A61B2018/0262 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/1467 , A61B2018/1472 , A61B2090/3614 , A61B2090/3782 , A61B2218/002 , A61F7/12 , A61M2025/1052 , A61M2025/1086 , A61M25/1002 , A61M3/0279 , C08L2201/12
摘要： A method of treating a sphincter provides a catheter means and an energy delivery device means coupled to the catheter means. The energy delivery device means has a tissue piercing distal end. The catheter means is introduced into an esophagus. A sphincter exterior surface is pierced with the energy delivery device means tissue piercing distal. The energy delivery device means tissue piercing distal end is advanced a sufficient distance in an interior of the sphincter to a tissue site. Energy is controllably delivered to the tissue site. Controlled cell necrosis is created in the sphincter to reduce a frequency of sphincter relaxation.
摘要翻译：治疗括约肌的方法提供了一种导管装置和耦合到导管装置的能量输送装置装置。能量输送装置装置具有组织刺穿的远端。将导管装置引入食道。括约肌外表面被刺穿，能量输送装置意指组织穿刺远端。能量输送装置意味着组织刺穿的远端在括约肌内部前进足够的距离到组织部位。能量被可控地传递到组织部位。在括约肌中产生受控细胞坏死，以减少括约肌松弛的频率。

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