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81. 发明授权

US09492014B1 Mesh folding chair 有权
标题翻译：网折叠椅
公开(公告)号：US09492014B1
公开(公告)日：2016-11-15
申请号：US13245339
申请日：2011-09-26
申请人： Richard D. Smith , Orrin C. Farnsworth
发明人： Richard D. Smith , Orrin C. Farnsworth
IPC分类号： A47C4/00 , A47C4/44 , A47C5/06
CPC分类号： A47C4/44 , A47C3/04 , A47C4/28 , A47C4/38 , A47C5/06 , A47C7/002 , A47C7/282
摘要： A folding mesh chair includes a seat and a backrest carried between opposite frame sides. The chair has an unfolded seating position in which the seat pivots to extend from the frame sides and bottoms of front and rear legs move apart, and a folded position in which the seat pivots toward the frame sides and the front and rear legs move together. One or both of the seat and the backrest have a continuous sheet of flexible and elastic mesh or patterned open texture plastic held across and substantially covering an opening in an all-plastic hoop fixed between the frame sides.
摘要翻译：折叠网椅包括座位和靠在相对的框架侧之间的靠背。椅子具有展开的就座位置，其中座椅枢转以从框架侧面延伸，前后腿的底部移动分开，并且座椅朝向框架侧部枢转并且前后腿部一起移动的折叠位置。座椅和靠背中的一个或两个具有连续的柔性和弹性网格片或图案化的开放纹理塑料，其保持横跨并且基本上覆盖固定在框架侧之间的全塑性环箍中的开口。

82. 发明授权

US09245725B2 Ion trap device 有权
标题翻译：离子阱装置
公开(公告)号：US09245725B2
公开(公告)日：2016-01-26
申请号：US14179008
申请日：2014-02-12
申请人： Yehia M. Ibrahim , Richard D. Smith
发明人： Yehia M. Ibrahim , Richard D. Smith
IPC分类号： H01J49/34 , H01J49/06
CPC分类号： H01J49/065
摘要： An ion trap device is disclosed. The device includes a series of electrodes that define an ion flow path. A radio frequency (RF) field is applied to the series of electrodes such that each electrode is phase shifted approximately 180 degrees from an adjacent electrode. A DC voltage is superimposed with the RF field to create a DC gradient to drive ions in the direction of the gradient. A second RF field or DC voltage is applied to selectively trap and release the ions from the device. Further, the device may be gridless and utilized at high pressure.
摘要翻译：公开了一种离子阱装置。该装置包括限定离子流动路径的一系列电极。射频（RF）场被施加到一系列电极，使得每个电极与相邻电极相差大约180度。直流电压与RF场叠加以产生沿梯度方向驱动离子的直流梯度。施加第二RF场或DC电压以选择性地从装置中捕集和释放离子。此外，该装置可以是无栅极的并且在高压下使用。

83. 发明授权

US09063086B1 Method and apparatus for compressing ions 有权
标题翻译：用于压缩离子的方法和装置
公开(公告)号：US09063086B1
公开(公告)日：2015-06-23
申请号：US14179329
申请日：2014-02-12
申请人： Sandilya V. B. Garimella , Yehia M. Ibrahim , Gordon A. Anderson , Richard D. Smith
发明人： Sandilya V. B. Garimella , Yehia M. Ibrahim , Gordon A. Anderson , Richard D. Smith
IPC分类号： G01N27/62 , H01J49/00 , H01J49/10
CPC分类号： G01N27/622
摘要： A method and apparatus for compressing ions inside an ion mobility device is disclosed. Ions are introduced into the mobility device. The ions are subjected to a non-constant electric field to form a potential gradient along a portion of the device so that ions with similar mobilities bunch together into sharper peaks while maintaining separation between other ions. The potential gradient progressively increases or decreases along the length of the device.
摘要翻译：公开了一种用于在离子迁移率装置内压缩离子的方法和装置。离子被引入到移动设备中。离子受到非恒定电场以沿器件的一部分形成电位梯度，使得具有相似迁移率的离子聚集在一起成为更尖锐的峰，同时保持其他离子之间的分离。电位梯度沿器件的长度逐渐增加或减小。

84. 发明申请

US20130104781A1 CONVERTIBLE TABLETOP WITH PIVOTAL MODESTY PANEL 有权
标题翻译：可折叠板与原型模块面板
公开(公告)号：US20130104781A1
公开(公告)日：2013-05-02
申请号：US13283077
申请日：2011-10-27
申请人： Richard D. Smith , Grant Rogers
发明人： Richard D. Smith , Grant Rogers
IPC分类号： A47B37/00
CPC分类号： A47B1/04 , A47B2200/0035 , A47B2200/12
摘要： A convertible table has a modesty panel pivotally coupled to a tabletop by a hinge fixed to the tabletop. The modesty panel is slidably coupled to the hinge and movable towards and away from the tabletop.
摘要翻译：可转换台具有通过固定在桌面上的铰链枢转地联接到桌面的谦虚面板。谦虚的面板可滑动地联接到铰链并且可朝向和远离桌面移动。

85. 发明申请

US20100181807A1 MESH CHAIR WITH OPEN-END HOOP 有权
标题翻译：具有开放式屋顶的MESH椅子
公开(公告)号：US20100181807A1
公开(公告)日：2010-07-22
申请号：US12748823
申请日：2010-03-29
申请人： Richard D. Smith
发明人： Richard D. Smith
IPC分类号： A47C7/00 , A47C7/02 , A47C3/04 , A47C4/04
CPC分类号： A47C3/04 , A47C4/28 , A47C4/48 , A47C7/282
摘要： A folding or stacking chair has a seat and a backrest carried between opposite frame sides each with a backrest support, a front leg and a rear leg. One or both of the seat and the backrest has a continuous sheet of flexible and elastic knitted mesh or patterned open texture plastic held across and substantially covering an opening in an open-end hoop coupled between the frame sides. An open-end of the hoop faces in a front or a back orientation for the seat, or a top or a bottom orientation for the backrest, with sides of the hoop attached to the frame sides. The sheet of mesh or textured plastic has a finished edge spanning the open-end of the hoop.
摘要翻译：折叠或折叠椅子具有座椅和靠背，其在相对的框架侧面之间承载，每个座椅具有靠背支撑件，前腿部和后腿部。座椅和靠背中的一个或两个具有柔性和弹性的针织网或图案化的开放纹理塑料的连续片，该织物保持横跨并且基本上覆盖耦合在框架侧之间的开口箍中的开口。箍的开口端面朝向座椅的前方或后方，或用于靠背的顶部或底部方向，箍的侧面连接到框架侧。网状或纹理化的塑料片具有跨越箍的开口端的成品边缘。

86. 发明申请

US20100161530A1 METHOD FOR ENHANCED ACCURACY IN PREDICTING PEPTIDES ELUTION TIME USING LIQUID SEPARATIONS OR CHROMATOGRAPHY 审中-公开
标题翻译：使用液相分离或色谱法预测肽时间的增强精度的方法
公开(公告)号：US20100161530A1
公开(公告)日：2010-06-24
申请号：US12573738
申请日：2009-10-05
申请人： Konstantinos Petritis , Lars J. Kangas , Gordon A. Anderson , Richard D. Smith
发明人： Konstantinos Petritis , Lars J. Kangas , Gordon A. Anderson , Richard D. Smith
IPC分类号： G06N3/12 , G06N3/08 , G06F15/18
CPC分类号： G01N33/6806 , G01N30/8693 , G01N2030/8831 , G16B40/00
摘要： A method for predicting the elution time of a peptide in chromatographic and electrophoretic separations by first providing a data set of known elution times of known peptides, then creating a plurality of vectors, each vector having a plurality of dimensions, and each dimension representing positional information about at least a portion of the amino acids present in the known peptides. A hypothetical vector is then created by assigning dimensional values for at least one hypothetical peptide, and a predicted elution time for the hypothetical vector is created by performing at least one multivariate regression fitting the hypothetical peptide to the plurality of vectors. Preferably, the multivariate regression is accomplished by the use of an artificial neural network and the elution times are first normalized using linear regression.
摘要翻译：通过首先提供已知肽的已知洗脱时间的数据集，然后产生多个向量，每个载体具有多个维度，并且每个维度表示位置信息，用于预测肽在色谱和电泳分离中的洗脱时间的方法约至少一部分已知肽中存在的氨基酸。然后通过为至少一个假想肽分配尺寸值来产生假想载体，并且通过对多个载体进行拟合假想肽的至少一个多变量回归而产生假设载体的预测洗脱时间。优选地，通过使用人造神经网络实现多变量回归，并且首先使用线性回归归一化洗脱时间。

87. 发明申请

US20100043679A1 SLAT TABLETOP WITH END CAPS 审中-公开
标题翻译：带顶端的SLAT TABLETOP
公开(公告)号：US20100043679A1
公开(公告)日：2010-02-25
申请号：US12197606
申请日：2008-08-25
申请人： David J. Laws , Richard D. Smith , Brandon Ross
发明人： David J. Laws , Richard D. Smith , Brandon Ross
IPC分类号： A47B13/08 , A47B7/00
CPC分类号： A47B95/043
摘要： A tabletop formed from slats for use in rigid, light-weight tables, such as portable banquet tables. The tabletop includes a center section formed from a plurality of open-channel, rectangular tubular slats that are laterally coupled together. Each slat has a top wall that aligns with top walls to form the upper working surface of the tabletop. Each slat also has downwardly-projecting sidewalls and a bottom wall with a longitudinal slot running the length of the slat to form the rectangular, downwardly-orientated channel. The adjacent contacting sidewalls of adjacent slats coupled together to form substantially vertical support beams. The tabletop further includes a pair of elongate end caps disposed on opposite ends and spanning the plurality of slats of the center section, with each end cap having a plurality of finger pairs extending into the plurality of slats with a center slot the receives a support beam therein.
摘要翻译：由板条形成的桌子，用于刚性，重量轻的桌子，如便携式宴会桌。桌面包括由横向耦合在一起的多个开放通道的矩形管状板条形成的中心部分。每个板条具有与顶壁对准的顶壁以形成台面的上工作表面。每个板条还具有向下突出的侧壁和底壁，其纵向狭槽延伸出板条的长度以形成矩形的向下定向的通道。相邻板条的相邻接触侧壁联接在一起以形成基本垂直的支撑梁。桌面还包括设置在相对端并跨越中心部分的多个板条的一对细长端帽，每个端盖具有延伸到多个板条中的多个手指对，中心狭槽接收支撑梁其中。

88. 发明授权

US07351964B2 Ion funnel with extended mass range and reduced conductance limit aperture 失效
标题翻译：离子漏斗具有扩展的质量范围和减小的电导限制孔径
公开(公告)号：US07351964B2
公开(公告)日：2008-04-01
申请号：US11251528
申请日：2005-09-30
申请人： Aleksey V. Tolmachev , Richard D. Smith
发明人： Aleksey V. Tolmachev , Richard D. Smith
IPC分类号： B01D59/44 , H01J49/00
CPC分类号： H01J49/067 , H01J49/066
摘要： An improved ion funnel design is disclosed that decreases the axial RF (parasite) fields at the ion funnel exit. This is achieved by addition of one or more compensation electrodes after the conductance limit electrode. Various RF voltage profiles may be applied to the various electrodes minimizing the parasite axial potential wells. The smallest RF aperture that serves as the conductance limiting electrode is further reduced over standard designs. Overall, the ion funnel improves transmission ranges of both low m/z and high m/z ions, reducing RF activation of ions and decreasing the gas load to subsequent differential pumping stages.
摘要翻译：公开了一种改进的离子漏斗设计，其减少了离子漏斗出口处的轴向RF（寄生）场。这是通过在电导限制电极之后添加一个或多个补偿电极来实现的。各种RF电压分布可以被施加到使寄生虫轴向势阱最小化的各种电极。用作电导限制电极的最小RF孔径比标准设计进一步降低。总的来说，离子漏斗改善了低m / z和高m / z离子的透射范围，减少了离子的RF激发，并将气体负载降低到随后的差动泵送阶段。

89. 发明授权

US07136759B2 Method for enhanced accuracy in predicting peptides using liquid separations or chromatography 失效
标题翻译：使用液体分离或色谱法增强预测肽的准确性的方法
公开(公告)号：US07136759B2
公开(公告)日：2006-11-14
申请号：US10323387
申请日：2002-12-18
申请人： Lars J. Kangas , Kenneth J. Auberry , Gordon A. Anderson , Richard D. Smith
发明人： Lars J. Kangas , Kenneth J. Auberry , Gordon A. Anderson , Richard D. Smith
IPC分类号： G06F17/11 , G06F17/50 , G06F19/00
CPC分类号： G01N30/8693 , G01N33/6806 , G01N2030/8831 , G06F19/24
摘要： A method for predicting the elution time of a peptide in chromatographic and electrophoretic separations by first providing a data set of known elution times of known peptides, then creating a plurality of vectors, each vector having a plurality of dimensions, and each dimension representing the elution time of amino acids present in each of these known peptides from the data set. The elution time of any protein is then be predicted by first creating a vector by assigning dimensional values for the elution time of amino acids of at least one hypothetical peptide and then calculating a predicted elution time for the vector by performing a multivariate regression of the dimensional values of the hypothetical peptide using the dimensional values of the known peptides. Preferably, the multivariate regression is accomplished by the use of an artificial neural network and the elution times are first normalized using a transfer function.
摘要翻译：一种通过首先提供已知肽的已知洗脱时间的数据集，然后产生多个载体，每个载体具有多个维度，并且每个维度代表洗脱的方法，用于预测肽在色谱和电泳分离中的洗脱时间的方法来自数据集的这些已知肽各自存在的氨基酸的时间。然后通过首先通过分配至少一个假想肽的氨基酸的洗脱时间的维度值来产生载体，然后通过执行尺寸的多元回归来计算载体的预测洗脱时间来预测任何蛋白质的洗脱时间使用已知肽的尺寸值的假想肽的值。优选地，通过使用人造神经网络实现多元回归，并且首先使用传递函数归一化洗脱次数。

90. 发明授权

US06608302B2 Method for calibrating a Fourier transform ion cyclotron resonance mass spectrometer 失效
标题翻译：校准傅里叶变换离子回旋共振质谱仪的方法
公开(公告)号：US06608302B2
公开(公告)日：2003-08-19
申请号：US09870577
申请日：2001-05-30
申请人： Richard D. Smith , Christophe D. Masselon , Aleksey Tolmachev
发明人： Richard D. Smith , Christophe D. Masselon , Aleksey Tolmachev
IPC分类号： H01J4900
CPC分类号： H01J49/0009 , H01J49/38
摘要： A method for improving the calibration of a Fourier transform ion cyclotron resonance mass spectrometer wherein the frequency spectrum of a sample has been measured and the frequency (f) and intensity (I) of at least three species having known mass to charge (m/z) ratios and one specie having an unknown (m/z) ratio have been identified. The method uses the known (m/z) ratios, frequencies, and intensities at least three species to calculate coefficients A, B, and C, wherein the mass to charge ratio of a least one of the three species (m/z)i is equal to A f i + B f i 2 + C · G ⁡ ( I i ) f i Q wherein fi is the detected frequency of the specie, G(Ii) is a predetermined function of the intensity of the species, and Q is a predetermined exponent. Using the calculated values for A, B, and C, the mass to charge ratio of the unknown specie (m/z)ii is calculated as the sum of A f ii + B f ii 2 + C · G ⁡ ( I ii ) f ii Q wherein fii is the measured frequency of the unknown specie, and (Iii) is the measured intensity of the unknown specie.
摘要翻译：一种用于改进傅里叶变换离子回旋共振质谱仪的校准的方法，其中已经测量了样品的频谱，以及已知质量电荷的至少三种物质的频率（f）和强度（I）（m / z ）比例，并且已经鉴定了具有未知（m / z）比的一种物质。该方法使用至少三种物质的已知（m / z）比，频率和强度来计算系数A，B和C，其中三种物质（m / z）i中的至少一种的质荷比等于其中fi是物种的检测频率，G（Ii）是物种强度的预定函数，Q是预定指数。使用A，B和C的计算值，将未知物种（m / z）ii的质荷比计算为fii是未知物种的测量频率的总和，（Iii）是测量的未知物种的强度。

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