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1. 发明授权

US09063086B1 Method and apparatus for compressing ions 有权
标题翻译：用于压缩离子的方法和装置
公开(公告)号：US09063086B1
公开(公告)日：2015-06-23
申请号：US14179329
申请日：2014-02-12
申请人： Sandilya V. B. Garimella , Yehia M. Ibrahim , Gordon A. Anderson , Richard D. Smith
发明人： Sandilya V. B. Garimella , Yehia M. Ibrahim , Gordon A. Anderson , Richard D. Smith
IPC分类号： G01N27/62 , H01J49/00 , H01J49/10
CPC分类号： G01N27/622
摘要： A method and apparatus for compressing ions inside an ion mobility device is disclosed. Ions are introduced into the mobility device. The ions are subjected to a non-constant electric field to form a potential gradient along a portion of the device so that ions with similar mobilities bunch together into sharper peaks while maintaining separation between other ions. The potential gradient progressively increases or decreases along the length of the device.
摘要翻译：公开了一种用于在离子迁移率装置内压缩离子的方法和装置。离子被引入到移动设备中。离子受到非恒定电场以沿器件的一部分形成电位梯度，使得具有相似迁移率的离子聚集在一起成为更尖锐的峰，同时保持其他离子之间的分离。电位梯度沿器件的长度逐渐增加或减小。

2. 发明授权

US09704701B2 Method and device for ion mobility separations 有权
公开(公告)号：US09704701B2
公开(公告)日：2017-07-11
申请号：US14851935
申请日：2015-09-11
申请人： Yehia M. Ibrahim , Sandilya V. B. Garimella , Richard D. Smith
发明人： Yehia M. Ibrahim , Sandilya V. B. Garimella , Richard D. Smith
IPC分类号： H01J49/26 , H01J49/40 , G01N27/62
CPC分类号： H01J49/26 , G01N27/622 , H01J49/0013 , H01J49/022 , H01J49/40
摘要： Methods and devices for ion separations or manipulations in gas phase are disclosed. The device includes a single non-planar surface. Arrays of electrodes are coupled to the surface. A combination of RF and DC voltages are applied to the arrays of electrodes to create confining and driving fields that move ions through the device. The DC voltages are static DC voltages or time-dependent DC potentials or waveforms.

3. 发明申请

US20170076931A1 METHOD AND DEVICE FOR ION MOBILITY SEPARATIONS 有权
标题翻译：用于离子移动分离的方法和装置
公开(公告)号：US20170076931A1
公开(公告)日：2017-03-16
申请号：US14851935
申请日：2015-09-11
申请人： Yehia M. Ibrahim , Sandilya V. B. Garimella , Richard D. Smith
发明人： Yehia M. Ibrahim , Sandilya V. B. Garimella , Richard D. Smith
IPC分类号： H01J49/26 , G01N27/62
CPC分类号： H01J49/26 , G01N27/622 , H01J49/0013 , H01J49/022 , H01J49/40
摘要： Methods and devices for ion separations or manipulations in gas phase are disclosed. The device includes a single non-planar surface. Arrays of electrodes are coupled to the surface. A combination of RF and DC voltages are applied to the arrays of electrodes to create confining and driving fields that move ions through the device. The DC voltages are static DC voltages or time-dependent DC potentials or waveforms.
摘要翻译：公开了用于气相中离子分离或操作的方法和装置。该装置包括单个非平面表面。电极阵列耦合到表面。将RF和DC电压的组合施加到电极阵列以产生将离子移动通过器件的限制和驱动场。直流电压是静态直流电压或时间依赖直流电位或波形。

4. 发明授权

US08772711B1 Apparatus and method of dissociating ions in a multipole ion guide 有权
标题翻译：在多极离子导向器中离子离子的装置和方法
公开(公告)号：US08772711B1
公开(公告)日：2014-07-08
申请号：US14011529
申请日：2013-08-27
申请人： Ian K. Webb , Keqi Tang , Richard D. Smith , Yehia M. Ibrahim , Gordon A. Anderson
发明人： Ian K. Webb , Keqi Tang , Richard D. Smith , Yehia M. Ibrahim , Gordon A. Anderson
IPC分类号： H01J49/42 , H01J49/26 , B01D59/44 , H01J49/06
CPC分类号： H01J49/063 , H01J49/0063
摘要： A method of dissociating ions in a multipole ion guide is disclosed. A stream of charged ions is supplied to the ion guide. A main RF field is applied to the ion guide to confine the ions through the ion guide. An excitation RF field is applied to one pair of rods of the ion guide. The ions undergo dissociation when the applied excitation RF field is resonant with a secular frequency of the ions. The multipole ion guide is, but not limited to, a quadrupole, a hexapole, and an octopole.
摘要翻译：公开了一种在多极离子导向器中离解离子的方法。将带电离子流供给到离子导向器。将主RF场施加到离子导向器以将离子限制在离子导向器上。激发RF场施加到离子导向器的一对杆上。当所施加的激发RF场与离子的长期频率谐振时，离子发生解离。多极离子导向器是但不限于四极，六极和八极。

5. 发明申请

US20140299766A1 ION MANIPULATION DEVICE 有权
标题翻译：离子操作装置
公开(公告)号：US20140299766A1
公开(公告)日：2014-10-09
申请号：US14146922
申请日：2014-01-03
申请人： Gordon A. Anderson , Richard D. Smith , Yehia M. Ibrahim , Erin M. Baker
发明人： Gordon A. Anderson , Richard D. Smith , Yehia M. Ibrahim , Erin M. Baker
IPC分类号： H01J49/06
CPC分类号： H01J49/062 , G01N27/622 , H01J49/06
摘要： An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. The device includes a first outer array of electrodes and a second outer array of electrodes. Each outer array of electrodes is positioned on either side of the inner electrodes, and is contained within and extends substantially along the length of each parallel surface. A DC voltage is applied to the first and second outer array of electrodes. A RF voltage, with a superimposed electric field, is applied to the inner electrodes by applying the DC voltages to each electrode. Ions either move between the parallel surfaces within an ion confinement area or along paths in the direction of the electric field, or can be trapped in the ion confinement area.
摘要翻译：公开了一种离子操作方法和装置。该装置包括一对基本上平行的表面。内部电极的阵列包含在每个平行表面内并且基本上沿着每个平行表面的长度延伸。该装置包括电极的第一外部阵列和第二外部电极阵列。每个外部电极阵列位于内部电极的任一侧上，并且基本上沿着每个平行表面的长度容纳并延伸。 DC电压施加到第一和第二外部电极阵列。通过向每个电极施加直流电压，将具有叠加电场的RF电压施加到内部电极。离子在离子限制区域内的平行表面之间或沿着电场方向的路径移动，或者可以被捕获在离子限制区域中。

6. 发明申请

US20150076343A1 ION MANIPULATION DEVICE TO PREVENT LOSS OF IONS 有权
标题翻译：离子操作装置，以防止失去的离子
公开(公告)号：US20150076343A1
公开(公告)日：2015-03-19
申请号：US14528917
申请日：2014-10-30
申请人： Aleksey Tolmachev , Richard D. Smith , Yehia M. Ibrahim , Gordon A. Anderson , Erin M. Baker
发明人： Aleksey Tolmachev , Richard D. Smith , Yehia M. Ibrahim , Gordon A. Anderson , Erin M. Baker
IPC分类号： H01J49/06
CPC分类号： H01J49/062 , G01N27/622 , H01J49/06
摘要： An ion manipulation method and device to prevent loss of ions is disclosed. The device includes a pair of surfaces. An inner array of electrodes is coupled to the surfaces. A RF voltage and a DC voltage are alternately applied to the inner array of electrodes. The applied RF voltage is alternately positive and negative so that immediately adjacent or nearest neighbor RF applied electrodes are supplied with RF signals that are approximately 180 degrees out of phase.
摘要翻译：公开了一种用于防止离子损失的离子操作方法和装置。该装置包括一对表面。电极的内部阵列耦合到表面。 RF电压和DC电压交替施加到电极的内部阵列。施加的RF电压交替地是正的和负的，使得紧邻或最近邻RF施加的电极被提供有大约相差180度的RF信号。

7. 发明授权

US08907273B1 Vacuum chamber for ion manipulation device 有权
标题翻译：离子操作装置真空室
公开(公告)号：US08907273B1
公开(公告)日：2014-12-09
申请号：US14292437
申请日：2014-05-30
申请人： Tsung-Chi Chen , Keqi Tang , Yehia M. Ibrahim , Richard D. Smith , Gordon A. Anderson , Erin M. Baker
发明人： Tsung-Chi Chen , Keqi Tang , Yehia M. Ibrahim , Richard D. Smith , Gordon A. Anderson , Erin M. Baker
IPC分类号： H01J49/06
CPC分类号： H01J49/062 , G01N27/622 , H01J49/06
摘要： An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. The device includes a first outer array of electrodes and a second outer array of electrodes. Each outer array of electrodes is positioned on either side of the inner electrodes, and is contained within and extends substantially along the length of each parallel surface. A DC voltage is applied to the first and second outer array of electrodes. A RF voltage, with a superimposed electric field, is applied to the inner electrodes by applying the DC voltages to each electrode. Ions either move between the parallel surfaces within an ion confinement area or along paths in the direction of the electric field, or can be trapped in the ion confinement area. A predetermined number of pairs of surfaces are disposed in one or more chambers, forming a multiple-layer ion mobility cyclotron device.
摘要翻译：公开了一种离子操作方法和装置。该装置包括一对基本平行的表面。内部电极的阵列包含在每个平行表面内并且基本上沿着每个平行表面的长度延伸。该装置包括电极的第一外部阵列和第二外部电极阵列。每个外部电极阵列位于内部电极的任一侧上，并且基本上沿着每个平行表面的长度容纳并延伸。 DC电压施加到第一和第二外部电极阵列。通过向每个电极施加直流电压，将具有叠加电场的RF电压施加到内部电极。离子在离子限制区域内的平行表面之间或沿着电场方向的路径移动，或者可以被捕获在离子限制区域中。预定数量的一对表面设置在一个或多个室中，形成多层离子迁移回旋加速器装置。

8. 发明授权

US08969800B1 Ion manipulation device to prevent loss of ions 有权
标题翻译：离子操纵装置，以防止离子损失
公开(公告)号：US08969800B1
公开(公告)日：2015-03-03
申请号：US14528917
申请日：2014-10-30
申请人： Aleksey Tolmachev , Richard D. Smith , Yehia M. Ibrahim , Gordon A. Anderson , Erin M. Baker
发明人： Aleksey Tolmachev , Richard D. Smith , Yehia M. Ibrahim , Gordon A. Anderson , Erin M. Baker
IPC分类号： H01J49/26
CPC分类号： H01J49/062 , G01N27/622 , H01J49/06
摘要： An ion manipulation method and device to prevent loss of ions is disclosed. The device includes a pair of surfaces. An inner array of electrodes is coupled to the surfaces. A RF voltage and a DC voltage are alternately applied to the inner array of electrodes. The applied RF voltage is alternately positive and negative so that immediately adjacent or nearest neighbor RF applied electrodes are supplied with RF signals that are approximately 180 degrees out of phase.
摘要翻译：公开了一种用于防止离子损失的离子操作方法和装置。该装置包括一对表面。电极的内部阵列耦合到表面。 RF电压和DC电压交替施加到电极的内部阵列。施加的RF电压交替地是正的和负的，使得紧邻或最近邻RF施加的电极被提供有大约相差180度的RF信号。

9. 发明授权

US08901490B1 Ion manipulation device with electrical breakdown protection 有权
标题翻译：离子操纵装置具有电击穿保护
公开(公告)号：US08901490B1
公开(公告)日：2014-12-02
申请号：US14292448
申请日：2014-05-30
申请人： Tsung-Chi Chen , Keqi Tang , Yehia M. Ibrahim , Richard D. Smith , Gordon A. Anderson , Erin M. Baker
发明人： Tsung-Chi Chen , Keqi Tang , Yehia M. Ibrahim , Richard D. Smith , Gordon A. Anderson , Erin M. Baker
IPC分类号： H01J49/42
CPC分类号： H01J49/062 , G01N27/622 , H01J49/06
摘要： An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. The device includes a first outer array of electrodes and a second outer array of electrodes. Each outer array of electrodes is positioned on either side of the inner electrodes, and is contained within and extends substantially along the length of each parallel surface. A DC voltage is applied to the first and second outer array of electrodes. A RF voltage, with a superimposed electric field, is applied to the inner electrodes by applying the DC voltages to each electrode. Ions either move between the parallel surfaces within an ion confinement area or along paths in the direction of the electric field, or can be trapped in the ion confinement area. The surfaces are housed in a chamber, and at least one electrically insulative shield is coupled to an inner surface of the chamber for increasing a mean-free-path between two adjacent electrodes in the chamber.
摘要翻译：公开了一种离子操作方法和装置。该装置包括一对基本平行的表面。内部电极的阵列包含在每个平行表面内并且基本上沿着每个平行表面的长度延伸。该装置包括电极的第一外部阵列和第二外部电极阵列。每个外部电极阵列位于内部电极的任一侧上，并且基本上沿着每个平行表面的长度容纳并延伸。 DC电压施加到第一和第二外部电极阵列。通过向每个电极施加直流电压，将具有叠加电场的RF电压施加到内部电极。离子在离子限制区域内的平行表面之间或沿着电场方向的路径移动，或者可以被捕获在离子限制区域中。表面容纳在腔室中，并且至少一个电绝缘屏蔽件联接到腔室的内表面，以增加腔室中两个相邻电极之间的平均自由程。

10. 发明授权

US08835839B1 Ion manipulation device 有权
标题翻译：离子操纵装置
公开(公告)号：US08835839B1
公开(公告)日：2014-09-16
申请号：US14146922
申请日：2014-01-03
申请人： Gordon A. Anderson , Richard D. Smith , Yehia M. Ibrahim , Erin M. Baker
发明人： Gordon A. Anderson , Richard D. Smith , Yehia M. Ibrahim , Erin M. Baker
IPC分类号： H01J49/06
CPC分类号： H01J49/062 , G01N27/622 , H01J49/06
摘要： An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. The device includes a first outer array of electrodes and a second outer array of electrodes. Each outer array of electrodes is positioned on either side of the inner electrodes, and is contained within and extends substantially along the length of each parallel surface. A DC voltage is applied to the first and second outer array of electrodes. A RF voltage, with a superimposed electric field, is applied to the inner electrodes by applying the DC voltages to each electrode. Ions either move between the parallel surfaces within an ion confinement area or along paths in the direction of the electric field, or can be trapped in the ion confinement area.
摘要翻译：公开了一种离子操作方法和装置。该装置包括一对基本上平行的表面。内部电极的阵列包含在每个平行表面内并且基本上沿着每个平行表面的长度延伸。该装置包括电极的第一外部阵列和第二外部电极阵列。每个外部电极阵列位于内部电极的任一侧上，并且基本上沿着每个平行表面的长度容纳并延伸。 DC电压施加到第一和第二外部电极阵列。通过向每个电极施加直流电压，将具有叠加电场的RF电压施加到内部电极。离子在离子限制区域内的平行表面之间或沿着电场方向的路径移动，或者可以被捕获在离子限制区域中。

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