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81. 发明申请

US20100273675A1 Methods for detecting fetal abnormality 审中-公开
标题翻译：检测胎儿异常的方法
公开(公告)号：US20100273675A1
公开(公告)日：2010-10-28
申请号：US12702614
申请日：2010-02-09
申请人： Ulysses J. Balis , Mehmet Toner , Ravi Kapur , John Walsh
发明人： Ulysses J. Balis , Mehmet Toner , Ravi Kapur , John Walsh
IPC分类号： C40B30/04 , C12Q1/68
CPC分类号： C12Q1/6881 , B01L3/502746 , B01L3/502753 , B01L3/502761 , B01L2200/0668 , B01L2300/0816 , B01L2400/0487 , B01L2400/086 , B82Y15/00 , B82Y30/00 , C12Q2600/156 , G01N2015/1486
摘要： The invention relates to a method of identifying fetal abnormality from a maternal blood sample by capturing an image of a fetal nucleated red blood cell obtained from the maternal blood sample; inputting probe intensities for a plurality of nucleic acid probes that bind fetal nucleic acids of interest; analyzing the probe intensities; and generating a diagnostic output according to results of the analysis. In some embodiments, the probes are specific to a chromosome.
摘要翻译：本发明涉及一种从母体血液样本中鉴别胎儿异常的方法，该方法是从母体血液样品中获取胎儿有核红细胞的图像，输入结合感兴趣的胎儿核酸的多个核酸探针的探针强度; 分析探针强度; 并根据分析结果生成诊断输出。在一些实施方案中，探针对染色体是特异性的。

82. 发明授权

US07803608B2 Integrated filtration and detection device 有权
标题翻译：集成过滤和检测装置
公开(公告)号：US07803608B2
公开(公告)日：2010-09-28
申请号：US10084578
申请日：2002-02-27
申请人： James L. DiGuiseppi , Diederik Engbersen , Scott R. Jeffrey , John Walsh
发明人： James L. DiGuiseppi , Diederik Engbersen , Scott R. Jeffrey , John Walsh
IPC分类号： C12M1/34
CPC分类号： C12M41/26 , C12M29/04 , C12M41/34
摘要： An integrated filtration and detection device for collecting and detecting the growth of microorganisms in a specimen includes a container defining a chamber therein. The container has an inlet and an outlet in fluid communication with the chamber. A filter is mounted in the chamber between the inlet and the outlet. A sensor is mounted in the chamber. The sensor is operative to exhibit a change in a measurable property thereof upon exposure to changes in the chamber due to microbial growth.
摘要翻译：用于收集和检测试样中微生物生长的集成过滤和检测装置包括在其中限定室的容器。容器具有与腔室流体连通的入口和出口。过滤器安装在入口和出口之间的腔室中。传感器安装在腔室中。当由于微生物生长而暴露于室内的变化时，该传感器可操作地表现出其可测量性质的变化。

83. 发明申请

US20090282678A1 Methods of Maintaining Turbine Discs to Avert Critical Bucket Attachment Dovetail Cracks 有权
标题翻译：维护涡轮盘避免重要铲斗附件燕尾裂纹的方法
公开(公告)号：US20090282678A1
公开(公告)日：2009-11-19
申请号：US12463931
申请日：2009-05-11
申请人： Andrew D. Williams , William Calder , John Walsh
发明人： Andrew D. Williams , William Calder , John Walsh
IPC分类号： B23P6/00
CPC分类号： F01D5/005 , B23P6/002 , B23P6/045 , F01D5/3092 , F05D2230/80 , F05D2230/90 , Y10T29/49318
摘要： Methods of to maintaining turbine discs prone to cracks in bucket attachment dovetails are disclosed. In one embodiment, wherein a turbine disc comprises a plurality of bucket attachment dovetail regions, one or more of the bucket attachment dovetail regions comprises a cooling slot, and each cooling slot comprises edges and adjacent surfaces, a method comprises inspecting the one or more of the bucket attachment dovetail regions comprising a cooling slot to confirm that each bucket attachment dovetail region meets predetermined minimum standards. The method further comprises blending the edges of the at least one of the cooling slots. The method further comprises polishing the edges of the at least one of the cooling slots. The method further comprises peening the edges of the at least one of the cooling slots. The method further comprises coating the edges and adjacent surfaces of at least one of the cooling slots.
摘要翻译：公开了保持涡轮盘容易在铲斗装卸燕尾裂缝的方法。在一个实施例中，其中涡轮盘包括多个铲斗附接燕尾区域，所述铲斗附接燕尾区域中的一个或多个包括冷却槽，并且每个冷却槽包括边缘和相邻表面，一种方法包括：检查一个或多个所述铲斗附接燕尾区域包括冷却槽，以确认每个铲斗附接燕尾形区域满足预定的最小标准。该方法还包括混合至少一个冷却槽的边缘。该方法还包括抛光至少一个冷却槽的边缘。该方法还包括对这些冷却槽中的至少一个的边缘进行喷丸处理。该方法还包括涂覆至少一个冷却槽的边缘和相邻表面。

84. 发明申请

US20080273422A2 METHOD FOR CHARACTERIZING SHEAR WAVE FORMATION ANISOTROPY 审中-公开
公开(公告)号：US20080273422A2
公开(公告)日：2008-11-06
申请号：US11940236
申请日：2007-11-14
申请人： J. Donald , Tom Bratton , John Walsh
发明人： J. Donald , Tom Bratton , John Walsh
IPC分类号： G01V1/30
CPC分类号： G01V1/50 , G01V1/284 , G01V2210/626
摘要： A method of characterizing shear wave anisotropy in a formation includes obtaining crossed-dipole waveforms from a borehole penetrating the formation over a range of depths and frequencies, determining far-field slowness in a fast-shear and slow-shear direction using a low-frequency portion of the crossed-dipole waveforms, and determining near-wellbore slowness in the fast-shear and slow-shear directions using a high-frequency portion of the crossed-dipole waveforms. The method also includes marking a selected depth of the formation as having intrinsic anisotropy if at the selected depth the far-field slowness in the fast-shear direction is less than the far-field slowness in the slow-shear direction and the near-wellbore slowness in the fast-shear direction is less than the near-wellbore slowness in the slow-shear direction. The selected depth is marked as having stress-induced anisotropy if the far-field slowness in the fast-shear direction is less than the far-field slowness in the slow-shear direction and the near-wellbore slowness in the fast-shear direction is greater than the near-wellbore slowness in the slow-shear direction.

85. 发明申请

US20080194320A1 Three-Dimensional Gaming System Environments 审中-公开
标题翻译：三维游戏系统环境
公开(公告)号：US20080194320A1
公开(公告)日：2008-08-14
申请号：US12063643
申请日：2006-08-03
申请人： John Walsh , Larry Pacey , Jeremy Hornik
发明人： John Walsh , Larry Pacey , Jeremy Hornik
IPC分类号： A63F13/00
CPC分类号： G07F17/3202 , G07F17/3211
摘要： Methods and apparatus affecting the interaction between events, objects, and three-dimensional wagering game environment are described herein.
摘要翻译：本文描述了影响事件，对象和三维投注游戏环境之间的交互的方法和装置。

86. 发明申请

US20080106975A1 METHOD FOR CHARACTERIZING SHEAR WAVE FORMATION ANISOTROPY 审中-公开
标题翻译：用于表征剪切波形成方法的方法
公开(公告)号：US20080106975A1
公开(公告)日：2008-05-08
申请号：US11940236
申请日：2007-11-14
申请人： J. Donald , Tom Bratton , John Walsh
发明人： J. Donald , Tom Bratton , John Walsh
IPC分类号： G01V1/30
CPC分类号： G01V1/50 , G01V1/284 , G01V2210/626
摘要： A method of characterizing shear wave anisotropy in a formation includes obtaining crossed-dipole waveforms from a borehole penetrating the formation over a range of depths and frequencies, determining far-field slowness in a fast-shear and slow-shear direction using a low-frequency portion of the crossed-dipole waveforms, and determining near-wellbore slowness in the fast-shear and slow-shear directions using a high-frequency portion of the crossed-dipole waveforms. The method also includes marking a selected depth of the formation as having intrinsic anisotropy if at the selected depth the far-field slowness in the fast-shear direction is less than the far-field slowness in the slow-shear direction and the near-wellbore slowness in the fast-shear direction is less than the near-wellbore slowness in the slow-shear direction. The selected depth is marked as having stress-induced anisotropy if the far-field slowness in the fast-shear direction is less than the far-field slowness in the slow-shear direction and the near-wellbore slowness in the fast-shear direction is greater than the near-wellbore slowness in the slow-shear direction.
摘要翻译：表征地层中剪切波各向异性的方法包括从深度和频率范围穿透地层的钻孔获得交叉偶极子波形，使用低频确定快剪切和慢剪切方向的远场慢度交叉偶极子波形的一部分，并且使用交叉偶极子波形的高频部分确定快剪切和慢剪切方向的近井筒慢度。该方法还包括将所选地层的深度标记为具有固有的各向异性，如果在所选择的深度处，快剪切方向的远场慢度小于慢剪切方向的远场慢度和近井筒快剪切方向的缓慢小于慢剪切方向的近井筒慢度。如果快剪切方向的远场慢度小于慢剪切方向的远场慢度，则选择的深度被标记为具有应力诱导的各向异性，并且快剪切方向的近井筒慢度是大于慢剪切方向的近井眼缓慢。

87. 发明授权

US07356388B2 Prevention of interference from movable radiation networks 失效
标题翻译：防止可动辐射网络的干扰
公开(公告)号：US07356388B2
公开(公告)日：2008-04-08
申请号：US11418117
申请日：2006-05-05
申请人： Guy Waugh , Michael Fitzgerald , Christopher Young , Michael Godley , Richard Lord , John Walsh , David Sharp
发明人： Guy Waugh , Michael Fitzgerald , Christopher Young , Michael Godley , Richard Lord , John Walsh , David Sharp
IPC分类号： G05D1/00
CPC分类号： H04W24/02 , H04B7/18506 , H04B15/00 , H04W4/02 , H04W16/14 , H04W84/005 , H04W84/06
摘要： A radio interference avoidance system (1) has a processor in a detection system (11) which receives real time inputs from various sensors (12-16). The processor dynamically determines if a craft (for example, ship) movable network (19) is within an interference distance of a fixed network. It uses real time craft position data relative to fixed network position and also radiation characteristic data for both the movable (19) and fixed networks.
摘要翻译：无线电干扰避免系统（1）在接收来自各种传感器（12-16）的实时输入的检测系统（11）中具有处理器。处理器动态地确定船舶（例如船舶）可移动网络（19）是否在固定网络的干扰距离内。它使用相对于固定网络位置的实时工作位置数据以及可移动（19）和固定网络的辐射特性数据。

88. 发明授权

US07310285B2 Method for characterizing shear wave formation anisotropy 有权
标题翻译：表征剪切波形成各向异性的方法
公开(公告)号：US07310285B2
公开(公告)日：2007-12-18
申请号：US11196907
申请日：2005-08-04
申请人： J. Adam Donald , Tom R. Bratton , John Walsh
发明人： J. Adam Donald , Tom R. Bratton , John Walsh
IPC分类号： G01S15/00 , G01V1/00
CPC分类号： G01V1/50 , G01V1/284 , G01V2210/626
摘要： A method of characterizing shear wave anisotropy in a formation includes obtaining crossed-dipole waveforms from a borehole penetrating the formation over a range of depths and frequencies, determining far-field slowness in a fast-shear and slow-shear direction using a low-frequency portion of the crossed-dipole waveforms, and determining near-wellbore slowness in the fast-shear and slow-shear directions using a high-frequency portion of the crossed-dipole waveforms. The method also includes marking a selected depth of the formation as having intrinsic anisotropy if at the selected depth the far-field slowness in the fast-shear direction is less than the far-field slowness in the slow-shear direction and the near-wellbore slowness in the fast-shear direction is less than the near-wellbore slowness in the slow-shear direction. The selected depth is marked as having stress-induced anisotropy if the far-field slowness in the fast-shear direction is less than the far-field slowness in the slow-shear direction and the near-wellbore slowness in the fast-shear direction is greater than the near-wellbore slowness in the slow-shear direction.
摘要翻译：表征地层中剪切波各向异性的方法包括从深度和频率范围穿透地层的钻孔获得交叉偶极子波形，使用低频确定快剪切和慢剪切方向的远场慢度交叉偶极子波形的一部分，并且使用交叉偶极子波形的高频部分确定快剪切和慢剪切方向的近井筒慢度。该方法还包括将所选地层的深度标记为具有固有的各向异性，如果在所选择的深度处，快剪切方向的远场慢度小于慢剪切方向的远场慢度和近井筒快剪切方向的缓慢小于慢剪切方向的近井筒慢度。如果快剪切方向的远场慢度小于慢剪切方向的远场慢度，则选择的深度被标记为具有应力诱导的各向异性，并且快剪切方向的近井筒慢度是大于慢剪切方向的近井眼缓慢。

89. 发明授权

US06566190B2 Vertical internally-connected trench cell (V-ICTC) and formation method for semiconductor memory devices 失效
标题翻译：垂直内部连接的沟槽单元（V-ICTC）和半导体存储器件的形成方法
公开(公告)号：US06566190B2
公开(公告)日：2003-05-20
申请号：US09941689
申请日：2001-08-30
申请人： Brian S. Lee , John Walsh
发明人： Brian S. Lee , John Walsh
IPC分类号： H01L2994
CPC分类号： H01L27/10864 , H01L27/10841 , H01L27/10867 , H01L27/10876 , H01L27/1203 , H01L29/66181
摘要： A dynamic random access memory (DRAM) device having a vertical transistor and an internally-connected strap (ICS) to connect the transistor to the capacitor. The ICS makes no direct contact with the substrate. The DRAM cell operates at a substantially lower cell capacitance than that required for a conventional buried strap trench (BEST) cell without causing any negative impact on device performance. The lower cell capacitance also extends the feasibility of deep trench capacitor manufacturing technology without requiring new materials or processing methods. A method of manufacturing the DRAM includes forming a very thin Si layer on top of a DT cell while at the same time the method forms an isolated layer replacing a conventional collar. The formation of the SOI by internal thermal oxidation (ITO) makes the structure in such a manner that the device may be fully depleted.
摘要翻译：具有垂直晶体管和内部连接的带（ICS）的动态随机存取存储器（DRAM）器件，用于将晶体管连接到电容器。 ICS不与基板直接接触。 DRAM单元以比常规掩埋带沟槽（BEST）单元所需的电容小得多的单元电容器工作，而不会对器件性能造成任何负面影响。较低的电池电容也扩大了深沟槽电容器制造技术的可行性，而不需要新的材料或加工方法。制造DRAM的方法包括在DT单元的顶部上形成非常薄的Si层，同时该方法形成代替传统套环的隔离层。通过内部热氧化（ITO）形成SOI使得该装置可以完全耗尽。

90. 发明授权

US06433021B1 Indane compounds and their pharmaceutical use 失效
标题翻译：吲哚化合物及其药物用途
公开(公告)号：US06433021B1
公开(公告)日：2002-08-13
申请号：US09453444
申请日：1999-12-03
申请人： Neil Frankish , Helen Sheridan , John Walsh , Michael Jordan
发明人： Neil Frankish , Helen Sheridan , John Walsh , Michael Jordan
IPC分类号： A61K3112
CPC分类号： C07C49/835 , C07C35/32 , C07C45/64 , C07C45/72 , C07C49/252 , C07C49/683 , C07C49/747 , C07C49/798
摘要： Indane compounds of general formulae (1) to (4) and their pharmaceutical use, particularly to achieve mast cell stabilising activity and/or anti-inflammatory activity are described. In these formulae R1 to R7 may be selected from: H, halo, hydroxy, alkoxy, aryloxy, acetoxy, carboxy, cyclopentyl, alkyl carbonyl, hydro carbonyl, amino, amido, alkylamino, hydroxyamino, amine oxide groups, azo groups, cyano, hydrazino groups, hydrazide groups, hydrazone groups, indane, indene, imide groups, iminoether groups, ureyl groups, oxime, nitro, nitrate, nitrite, nitroso groups, nitirile, heterocyclic groups containing hetero atoms selected from one or more of N, O or S, aralkyl groups, aryl groups, mono and polybenzoid aryl groups, substituted aryl groups, thiol, thioureyl, phenylthiol groups, sulphonic acid groups, sulphoxide groups, sulphone groups, carboxylic acid groups of C1 to C10 which may be substituted or unsubstituted, alkyl, substituted alkyl groups, acyl groups, substituted acyl groups; where R1 and R3 may together represent a double bond and wherein in (CH2)n, n is 0 to 8.
摘要翻译：描述了通式（1）至（4）的茚满化合物及其药物用途，特别是实现肥大细胞稳定活性和/或抗炎活性。在这些式中，R 1至R 7可以选自：H，卤素，羟基，烷氧基，芳氧基，乙酰氧基，羧基，环戊基，烷基羰基，氢羰基，氨基，酰氨基，烷基氨基，羟基氨基，氧化胺基，偶氮基，氰基，肼基，酰肼基，腙基，茚满，茚，酰亚胺基，亚氨基醚基，脲基，肟，硝基，硝酸根，亚硝酸根，亚硝基，亚硝基，含有选自N，O中的一个或多个的杂原子的杂环基， S，芳烷基，芳基，单和多亚苄基芳基，取代的芳基，硫醇，硫脲基，苯硫醇基，磺酸基，亚砜基，砜基，可被取代或未取代的C1至C10的羧酸基，烷基取代的烷基，酰基，取代的酰基; 其中R 1和R 3可以一起表示双键，并且其中在（CH 2）n中，n是0至8。

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