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81. 发明授权

US5782826A System and methods for detecting ancillary tissue near tissue targeted for ablation 失效
标题翻译：用于检测靶向消融组织附近组织的系统和方法
公开(公告)号：US5782826A
公开(公告)日：1998-07-21
申请号：US742628
申请日：1996-11-01
申请人： David K. Swanson
发明人： David K. Swanson
IPC分类号： A61B18/14 , A61N1/365 , A61B17/39
CPC分类号： A61B18/1492 , A61B2018/00214 , A61B2018/00267 , A61B2018/00577 , A61B2018/00839 , A61B2018/00898 , A61B2018/1253 , A61B2018/126 , A61N1/365
摘要： Systems and methods detect ancillary tissue within a tissue region targeted for ablation by locating a region to apply ablation energy to tissue targeted for ablation and applying energy within the region to stimulate selected ancillary tissue not targeted for ablation. The systems and methods sense when the selected ancillary tissue is affected by the stimulant energy within the region, thereby determining the presence of such ancillary tissue within the region. The systems and methods relocate the region until the selected ancillary tissue is not affected by the stimulant energy. The systems and methods then apply ablation energy in the region.
摘要翻译：系统和方法通过定位区域来检测针对消融的组织区域内的辅助组织，以将消融能量施加到组织靶向消融，并在该区域内施加能量以刺激未被靶向消融的选定辅助组织。当所选择的辅助组织受到该区域内的兴奋剂能量的影响时，系统和方法感测到，从而确定该区域内这种辅助组织的存在。系统和方法重新定位该区域，直到选定的辅助组织不受刺激能量的影响。系统和方法然后在该区域施加消融能量。

82. 发明授权

US5769847A Systems and methods for controlling tissue ablation using multiple temperature sensing elements 失效
标题翻译：使用多个温度感测元件控制组织消融的系统和方法
公开(公告)号：US5769847A
公开(公告)日：1998-06-23
申请号：US638989
申请日：1996-04-24
申请人： Dorin Nmi Panescu , James G. Whayne , Sidney D. Fleischman , David K. Swanson
发明人： Dorin Nmi Panescu , James G. Whayne , Sidney D. Fleischman , David K. Swanson
IPC分类号： A61B5/01 , A61B17/00 , A61B18/00 , A61B18/04 , A61B18/12 , A61B18/14 , A61B18/20 , A61M25/00 , A61N1/06 , G01K1/02 , G01K3/14 , A61B17/36
CPC分类号： A61B18/1206 , A61B18/00 , A61B18/12 , A61B18/1492 , G01K1/026 , G01K3/14 , A61B18/20 , A61B2017/00088 , A61B2017/00092 , A61B2017/00154 , A61B2017/003 , A61B2018/00083 , A61B2018/00095 , A61B2018/00101 , A61B2018/00107 , A61B2018/00148 , A61B2018/0016 , A61B2018/00357 , A61B2018/00577 , A61B2018/00636 , A61B2018/00654 , A61B2018/0066 , A61B2018/0069 , A61B2018/00702 , A61B2018/00726 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/00821 , A61B2018/00886 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/128 , A61B2018/1467
摘要： A system and associated method ablate body tissue using multiple emitters of ablating energy. The system and method convey ablating energy individually to each emitter in a sequence of power pulses. The system and method periodically sense temperature at each emitter and compare the sensed temperatures to a desired temperature established for all emitters to generate a signal individually for each emitter based upon the comparison. The system and method individually vary the power pulse to each emitter based upon the signal for that emitter to maintain the temperatures at all emitters essentially at the desired temperature during tissue ablation.
摘要翻译：一种系统和相关方法使用消融能量的多个发射器来消融身体组织。该系统和方法在功率脉冲序列中向每个发射器分别传递消融能量。该系统和方法周期性地感测每个发射器处的温度，并将所感测的温度与为所有发射器建立的期望温度进行比较，以基于该比较为每个发射器产生单独的信号。该系统和方法基于该发射器的信号单独改变每个发射器的功率脉冲，以在组织消融期间将所有发射体的温度基本保持在所需温度。

83. 发明授权

US5711305A Systems and methods for acquiring endocardially or epicardially paced electrocardiograms 失效
标题翻译：获得心内膜或心外膜心电图的系统和方法
公开(公告)号：US5711305A
公开(公告)日：1998-01-27
申请号：US393158
申请日：1995-02-17
申请人： David K. Swanson , James G. Whayne , Dorin Panescu
发明人： David K. Swanson , James G. Whayne , Dorin Panescu
IPC分类号： A61B1/005 , A61B5/042 , A61B5/0452 , A61B18/14 , A61N1/05 , G06F17/00 , G06F19/00 , A61B5/0402 , A61N1/36
CPC分类号： G06F19/3406 , A61B5/0422 , A61B5/04525 , A61B5/6855 , A61B5/6858 , A61N1/056 , G06F19/3487 , A61B1/0051 , A61B18/1492
摘要： Systems and methods acquire electrocardiograms using a first electrode associated with a region of heart tissue and a second body surface electrode. An analog or digital processing element is coupled to the first and second electrodes for conditioning the first electrode to emit a pacing signal and for conditioning the second electrode to sense paced electrocardiograms occurring as a result of the pacing signal. The systems and methods also employ a template of an electrocardiogram of a cardiac event of known diagnosis; for example an arrhythmia that the physician seeks to treat. This event-specific template comprises a plot of biopotentials over time and not a spacial distribution of endocardial surface activation. The systems and methods compare this event-specific template to a sample of a paced electrocardiogram. The paced electrocardiogram sample comprises a plot of biopotentials over time and not a spacial distribution of endocardial surface activation. The comparison yields a matching coefficient indicating how alike the input sample is to the input template. The matching coefficient can be used by the physician, for example, to aid in the location of sites that are potentially appropriate for ablation.
摘要翻译：系统和方法使用与心脏组织区域和第二体表电极相关联的第一电极获取心电图。模拟或数字处理元件耦合到第一和第二电极，用于调节第一电极以发出起搏信号并调节第二电极以感测由于起搏信号而产生的起搏心电图。系统和方法还采用已知诊断的心脏事件的心电图的模板; 例如医师寻求治疗的心律失常。该事件特定模板包括随时间的生物电势图，而不是心内膜表面活化的空间分布。系统和方法将此事件特定的模板与起搏心电图的样本进行比较。起搏心电图样本包括随时间的生物电势图，而不是心内膜表面活化的空间分布。比较产生一个表示输入样本与输入模板相似的匹配系数。例如，医生可以使用匹配系数来帮助可能适合于消融的部位的位置。

84. 发明授权

US5637090A Multiple electrode element for mapping and ablating heart tissue 失效
标题翻译：用于映射和消融心脏组织的多电极元件
公开(公告)号：US5637090A
公开(公告)日：1997-06-10
申请号：US655289
申请日：1996-05-15
申请人： David L. McGee , Russell A. Houser , David K. Swanson
发明人： David L. McGee , Russell A. Houser , David K. Swanson
IPC分类号： A61B5/042 , A61B17/00 , A61B18/14 , A61M25/00 , A61N1/06 , A61N1/40 , A61B5/04
CPC分类号： A61B5/6855 , A61B18/1492 , A61B5/0422 , A61B5/6857 , A61B5/6858 , A61N1/06 , A61N1/403 , A61B2017/00292 , A61B2017/003 , A61B2018/00107 , A61B2018/00148 , A61B2018/0016 , A61B2018/00357 , A61B2018/00577 , A61B2018/00839 , A61B2018/00869 , A61B2018/126 , A61B2018/1435 , A61B2018/1861 , A61B2562/0209 , A61B2562/043 , A61M2025/09141 , A61M25/0041
摘要： Systems and methods sense electrical events in heart tissue to identify the location of an arrhythmogenic focus for ablation. The systems and methods establish a contact site between heart tissue and a curvilinear electrode array. The systems and methods monitor signals representing electrical events sensed by the electrodes in the contact site. The signals are displayed as graphic information that represents the time sequence in which the electrodes sense a given electrical event. By moving the electrode array to one or additional contact sites in the general direction of the electrode that first sensed the electrical event, the physician homes in on a contact site in which all electrodes on the array sense the given electrical event at generally the same time. This contact site contains the arrhythmogenic focus. The systems and methods convey ablating energy to bipolar pairs of the electrodes to form large bipolar lesions in heart tissue.
摘要翻译：系统和方法检测心脏组织中的电事件以识别用于消融的致心律失常焦点的位置。系统和方法建立心脏组织和曲线电极阵列之间的接触部位。系统和方法监测表示由接触部位中的电极感测的电气事件的信号。信号被显示为表示电极感测给定电气事件的时间顺序的图形信息。通过将电极阵列移动到首先感测到电气事件的电极的大致方向上的一个或另外的接触位置，医生在接触位置处置于其中，其中阵列上的所有电极在大致相同的时间感测给定的电气事件。该接触部位包含致心律失常的焦点。系统和方法将烧蚀能量传递给双极电极对，以在心脏组织中形成大的双相病变。

85. 发明授权

US5603732A Subcutaneous defibrillation electrodes 失效
标题翻译：皮下除颤电极
公开(公告)号：US5603732A
公开(公告)日：1997-02-18
申请号：US554577
申请日：1995-11-06
申请人： Roger W. Dahl , David K. Swanson , Stephen J. Hahn , Douglas J. Lang , John E. Heil
发明人： Roger W. Dahl , David K. Swanson , Stephen J. Hahn , Douglas J. Lang , John E. Heil
IPC分类号： A61N1/05 , A61N1/375 , A61N1/39
CPC分类号： A61N1/05
摘要： Implantable electrodes for defibrillation are formed of pluralities of electrode segments. Each of the segments is relatively long and narrow. The electrode segments can be parallel and spaced apart from one another a distance at least ten times the nominal width, with one end of each segment mounted to a transverse distal portion of an electrically conductive lead coupling the electrode to a defibrillation pulse generator. Alternatively, segments can branch or radiate outwardly from a common junction. In yet another arrangement, electrode segments are portions of a single conductive path at the distal end of a lead from a pulse generator, arranged in either a spiral configuration or a serpentine configuration which can align electrode segments side by side, parallel and spaced apart. The electrode segments can be formed of composite conductors in the form of titanium ribbons or wires with a sputtered outer layer of platinum, or a silver core in a stainless steel tube, with a platinum layer formed onto the tube. The electrodes are highly compliant yet can provide large effective areas for defibrillation, enabling a transthoracic pulsing arrangement of two electrodes on opposite sides of the heart, implanted subcutaneously outside of the thoracic region.
摘要翻译：用于除颤的可植入电极由多个电极段形成。每个段都相对长而窄。电极段可以彼此平行和间隔至少十倍于标称宽度的距离，每个段的一端安装到将电极耦合到除颤脉冲发生器的导电引线的横向远端部分。或者，片段可以从公共接头向外分支或辐射。在另一种布置中，电极段是在来自脉冲发生器的引线的远端处的单个导电路径的部分，其布置成螺旋构造或蛇形结构，其可以并排并排隔离电极段。电极段可以由具有溅射的铂外层或不锈钢管中的银芯的钛带或电线形式的复合导体形成，铂层形成在管上。电极是高度依从性的，但可以为除颤提供大的有效区域，使得能够在心脏的相对侧上的两个电极的经胸部脉冲排列皮下植入胸部区域。

86. 发明授权

US5575810A Composite structures and methods for ablating tissue to form complex lesion patterns in the treatment of cardiac conditions and the like 失效
公开(公告)号：US5575810A
公开(公告)日：1996-11-19
申请号：US528805
申请日：1995-09-15
申请人： David K. Swanson , Sidney D. Fleischman , Thomas F. Kordis , David L. McGee
发明人： David K. Swanson , Sidney D. Fleischman , Thomas F. Kordis , David L. McGee
IPC分类号： A61B18/14 , A61N1/06
CPC分类号： A61B18/1492 , A61B2017/003 , A61B2018/00083 , A61B2018/00196 , A61B2018/00214 , A61B2018/00267 , A61B2018/00577 , A61B2018/00839 , A61B2018/1437 , A61B2018/1467 , A61B2018/1497
摘要： A method of ablating tissue in the heart to treat atrial fibrillation introduces into a selected atrium an energy emitting element. The method exposes the element to a region of the atrial wall and applies ablating energy to the element to thermally destroy tissue. The method forms a convoluted lesion pattern comprising elongated straight lesions and elongated curvilinear lesions. The lesion pattern directs electrical impulses within the atrial myocardium along a path that activates the atrial myocardium while interrupting reentry circuits that, if not interrupted, would cause fibrillation. The method emulates the surgical maze procedure, but lends itself to catheter-based procedures that do not require open heart surgical techniques. A composite structure for performing the method is formed using a template that displays in planar view a desired lesion pattern for the tissue. An array of spaced apart element is laid on the template. Guided by the template, energy emitting and non-energy emitting zones are formed on the elements. By overlaying the elements, the composite structure is formed, which can be introduced into the body to ablate tissue using catheter-based, vascular access techniques.

87. 发明授权

US5545202A Body implantable defibrillation system 失效
标题翻译：身体植入式除颤系统
公开(公告)号：US5545202A
公开(公告)日：1996-08-13
申请号：US285802
申请日：1994-08-04
申请人： Roger W. Dahl , David K. Swanson , Stephen J. Hahn , Douglas J. Lang , John E. Heil
发明人： Roger W. Dahl , David K. Swanson , Stephen J. Hahn , Douglas J. Lang , John E. Heil
IPC分类号： A61N1/05 , A61N1/375 , A61N1/39
CPC分类号： A61N1/05
摘要： Implantable electrodes for defibrillation are formed of pluralities of electrode segments. Each of the segments is relatively long and narrow. The electrode segments can be parallel and spaced apart from one another a distance at least ten times the nominal width, with one end of each segment mounted to a transverse distal portion of an electrically conductive lead coupling the electrode to a defibrillation pulse generator. Alternatively, segments can branch or radiate outwardly from a common junction. In yet another arrangement, electrode segments are portions of a single conductive path at the distal end of a lead from a pulse generator, arranged in either a spiral configuration or a serpentine configuration which can align electrode segments side by side, parallel and spaced apart. The electrode segments can be formed of composite conductors in the form of titanium ribbons or wires with a sputtered outer layer of platinum, or a silver core in a stainless steel tube, with a platinum layer formed onto the tube. The electrodes are highly compliant yet can provide large effective areas for defibrillation, enabling a transthoracic pulsing arrangement of two electrodes on opposite sides of the heart, implanted subcutaneously outside of the thoracic region.
摘要翻译：用于除颤的可植入电极由多个电极段形成。每个段都相对长而窄。电极段可以彼此平行和间隔至少十倍于标称宽度的距离，每个段的一端安装到将电极耦合到除颤脉冲发生器的导电引线的横向远端部分。或者，片段可以从公共接头向外分支或辐射。在另一种布置中，电极段是在来自脉冲发生器的引线的远端处的单个导电路径的部分，其布置成螺旋构造或蛇形结构，其可以并排并排隔离电极段。电极段可以由具有溅射的铂外层或不锈钢管中的银芯的钛带或电线形式的复合导体形成，铂层形成在管上。电极是高度依从性的，但可以为除颤提供大的有效区域，使得能够在心脏外侧皮下植入心脏两侧的两个电极的经胸部脉冲排列。

88. 发明授权

US5366496A Subcutaneous shunted coil electrode 失效
标题翻译：皮下分流线圈电极
公开(公告)号：US5366496A
公开(公告)日：1994-11-22
申请号：US41096
申请日：1993-04-01
申请人： Roger W. Dahl , Jayne G. Fangel , David K. Swanson
发明人： Roger W. Dahl , Jayne G. Fangel , David K. Swanson
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/0587 , A61N1/056
摘要： A body implantable cardioversion/defibrillation device includes an electrically conductive lead, three lead extensions coupled to the lead through a junction body, and an electrode array consisting of three electrodes, one electrode being coupled to each of the lead extensions. Each electrode has several separate electrically conductive paths, including a primary conductor in the form of a helically wound coil, and a linear shunt conductor in the form of a cable surrounded by the primary coil. The shunt cable is a composite, including a DBS core surrounded by an insulative coating. A dielectric sheath surrounds the shunt cable, preventing the cable from contacting the primary coil and isolating the shunt cable from contact with body tissue or body fluids. At each end of each electrode is a connector structure including a shunt connector attached to an end of the shunt cable, and an outer coil connector surrounding an end of the primary coil and the shunt connector. Both connectors are crimped to maintain the electrical and mechanical coupling. The junction body includes an electrically conductive plate having several bores directed inwardly into the plate. A thin wall portion on one side of each bore can be crimped following insertion of each lead or lead extension, to secure the electrical and mechanical connection.
摘要翻译：身体植入式心脏复律/除颤装置包括导电引线，通过连接体耦合到引线的三个引线延伸部分和由三个电极组成的电极阵列，一个电极耦合到每个引线延伸部分。每个电极具有几个单独的导电路径，包括螺旋卷绕线圈形式的主导体和由初级线圈围绕的电缆形式的线性分流导体。分流电缆是一种复合材料，包括被绝缘涂层包围的DBS芯。电介质护套围绕分流电缆，防止电缆接触初级线圈并隔离分流电缆与身体组织或体液的接触。在每个电极的每个端部处是连接器结构，其包括附接到分流电缆的端部的分流连接器和围绕初级线圈和分流连接器的端部的外部线圈连接器。两个连接器被压接以保持电气和机械耦合。接合体包括具有向内指向板的若干孔的导电板。每个孔的一侧上的薄壁部分可以在插入每个引线或引线延伸部之后被压接，以固定电气和机械连接。

89. 发明授权

US08636639B2 Signal transmitting and lesion excluding heart implants for pacing, defibrillating, and/or sensing of heart beat 有权
标题翻译：信号传播和病变，不包括用于起搏，除颤和/或心跳感测的心脏植入物
公开(公告)号：US08636639B2
公开(公告)日：2014-01-28
申请号：US13357369
申请日：2012-01-24
申请人： Lon S. Annest , Arthur A. Bertolero , David K. Swanson
发明人： Lon S. Annest , Arthur A. Bertolero , David K. Swanson
IPC分类号： A61N1/362
CPC分类号： A61B17/12122 , A61B17/1215 , A61F2/2487 , A61N1/057 , A61N1/3627 , A61N1/3956 , A61N1/3987
摘要： Devices, systems, and methods for treating a heart of a patient may make use of structures which limit a size of a chamber of the heart, such as by deploying a tensile member to bring a wall of the heart toward (optionally into contact with) a septum of the heart. The implant may include an electrode or other structure for applying pacing signals to one or both ventricles of the heart, for defibrillating the heart, for sensing beating of the heart or the like. A wireless telemetry and control system may allowing the implant to treat congestive heart failure, monitor the results of the treatment, and apply appropriate electrical stimulation.
摘要翻译：用于治疗患者心脏的装置，系统和方法可以利用限制心脏室的尺寸的结构，例如通过展开拉伸构件以将心脏的壁朝向（任选地接触）心脏隔膜植入物可以包括用于将起搏信号施加到心脏的一个或两个心室的电极或其他结构，用于使心脏去纤颤，用于感测心脏的跳动等。无线遥测和控制系统可以允许植入物治疗充血性心力衰竭，监测治疗结果，并施加适当的电刺激。

90. 发明授权

US08632532B2 Catheter with tissue protecting assembly 有权
标题翻译：导管与组织保护组件
公开(公告)号：US08632532B2
公开(公告)日：2014-01-21
申请号：US13551450
申请日：2012-07-17
申请人： Huy D. Phan , David K. Swanson
发明人： Huy D. Phan , David K. Swanson
IPC分类号： A61B18/14 , A61B18/18
CPC分类号： A61B18/082 , A61B5/042 , A61B18/1492 , A61B2018/00065 , A61B2018/00214 , A61B2018/00238 , A61B2018/00351 , A61B2018/1472 , A61B2090/0436
摘要： A medical probe includes an elongate member having a proximal end and a distal end, an ablative element mounted to the distal end of the elongate member, and a cage assembly mounted to the distal end of the elongate member, the cage assembly at least partially covers the ablative element. A method of treating tissue in a body includes inserting an ablative element in the body, placing the ablative element adjacent the tissue, and maintaining a distance between the ablative element and the tissue using a protective catheter element that circumscribes at least a portion of the ablative element.
摘要翻译：医疗探针包括具有近端和远端的细长构件，安装到细长构件的远端的消融元件和安装到细长构件的远端的保持架组件，保持架组件至少部分覆盖烧伤元素。一种在身体中处理组织的方法包括将可消融元件插入体内，将消融元件放置在组织附近，并使用保护性导管元件保持消融元件与组织之间的距离，所述保护性导管元件限定至少一部分烧蚀元件。

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