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1. 发明授权

US11026567B2 Methods and devices for minimally invasive cardiac surgery for atrial fibrillation 有权
公开(公告)号：US11026567B2
公开(公告)日：2021-06-08
申请号：US13117863
申请日：2011-05-27
申请人： Arthur A. Bertolero
发明人： Arthur A. Bertolero
IPC分类号： A61B1/12 , A61B17/22 , A61B18/14 , A61B5/24 , A61B17/00 , A61B18/00
摘要： Devices for enhancing minimally invasive cardiac surgery include a visualization device including an inflatable balloon at or near the distal end. Some visualization devices also include one or more lumens for allowing the introduction of one or more devices to a surgical site through the visualization device. Systems of the invention involve a visualization device which has at least one lumen for allowing introduction of an ablation device and/or other devices. A visualization device with an inflatable balloon may be positioned to create a space between a heart and pericardium when the balloon is inflated.

2. 发明授权

US08636639B2 Signal transmitting and lesion excluding heart implants for pacing, defibrillating, and/or sensing of heart beat 有权
标题翻译：信号传播和病变，不包括用于起搏，除颤和/或心跳感测的心脏植入物
公开(公告)号：US08636639B2
公开(公告)日：2014-01-28
申请号：US13357369
申请日：2012-01-24
申请人： Lon S. Annest , Arthur A. Bertolero , David K. Swanson
发明人： Lon S. Annest , Arthur A. Bertolero , David K. Swanson
IPC分类号： A61N1/362
CPC分类号： A61B17/12122 , A61B17/1215 , A61F2/2487 , A61N1/057 , A61N1/3627 , A61N1/3956 , A61N1/3987
摘要： Devices, systems, and methods for treating a heart of a patient may make use of structures which limit a size of a chamber of the heart, such as by deploying a tensile member to bring a wall of the heart toward (optionally into contact with) a septum of the heart. The implant may include an electrode or other structure for applying pacing signals to one or both ventricles of the heart, for defibrillating the heart, for sensing beating of the heart or the like. A wireless telemetry and control system may allowing the implant to treat congestive heart failure, monitor the results of the treatment, and apply appropriate electrical stimulation.
摘要翻译：用于治疗患者心脏的装置，系统和方法可以利用限制心脏室的尺寸的结构，例如通过展开拉伸构件以将心脏的壁朝向（任选地接触）心脏隔膜植入物可以包括用于将起搏信号施加到心脏的一个或两个心室的电极或其他结构，用于使心脏去纤颤，用于感测心脏的跳动等。无线遥测和控制系统可以允许植入物治疗充血性心力衰竭，监测治疗结果，并施加适当的电刺激。

3. 发明授权

US08123737B2 Multichannel catheter 有权
标题翻译：多通道导管
公开(公告)号：US08123737B2
公开(公告)日：2012-02-28
申请号：US10996876
申请日：2004-11-23
申请人： Arthur A. Bertolero , Raymond S. Bertolero , Jerome B. Riebman
发明人： Arthur A. Bertolero , Raymond S. Bertolero , Jerome B. Riebman
IPC分类号： A61M31/00
CPC分类号： A61B17/29 , A61B1/05 , A61B1/313 , A61B17/00234 , A61B17/0206 , A61B17/2812 , A61B17/320016 , A61B17/8085 , A61B46/10 , A61B90/36 , A61B90/37 , A61B90/50 , A61B2017/00199 , A61B2017/00243 , A61B2017/0046 , A61B2017/2904 , A61B2017/2905 , A61B2017/2946 , A61M1/3659 , A61M25/0029 , A61M25/0032 , A61M25/1027 , A61M2025/0031 , A61M2025/1052 , A61M2025/1086 , A61M2025/1097 , A61M2210/127
摘要： This invention is a single, multichannel catheter useful for extracorporeal circulation of blood to a patient undergoing cardiovascular treatments or surgery. The catheter has three independent channels and an expandable balloon at one end of the catheter. The first channel (34) is the largest and is of a size that allows for delivery of blood to a patient in an amount sufficient to maintain the patient's metabolism and perfusion throughout the treatment or surgery. A second channel (36), smaller than the first, is integrated into the wall of the first channel, and is suitable for delivering a biologically active fluid (e.g., for cardioplegia) to the heart and/or venting the left heart. A third channel (38), also smaller than the first, is integrated into the wall of the first channel, and suitable for delivering a fluid to the balloon for its expansion when positioned in the ascending aorta to occlude the flow of blood to the heart. It is important that the first channel accounts for at least about 70% of the total channel volume. The catheter provides an improved means of performing cardiovascular surgery on a patient using a cardiopulmonary machine for extracorporeal circulation of blood. The catheter is particularly useful for cardiac surgery. The multichannel catheter is best prepared using an extrusion molding technique.
摘要翻译：本发明是用于经历心血管治疗或手术的患者的体外血液循环的单通道多通道导管。导管具有三个独立的通道和在导管的一端的可膨胀气囊。第一通道（34）是最大的，并且具有允许以足以在整个治疗或手术中维持患者的新陈代谢和灌注的量向患者输送血液的尺寸。小于第一通道的第二通道（36）被集成到第一通道的壁中，并且适于将生物活性流体（例如用于心脏停跳）输送到心脏和/或排出左心脏。也比第一通道小的第三通道（38）被集成到第一通道的壁中，并且适合于当定位在升主动脉中时将流体输送到球囊以用于其膨胀，以将血液流动阻塞到心脏。重要的是，第一个频道占通道总容量的至少约70％。该导管提供了一种使用心肺机器对血液进行体外循环的患者进行心血管手术的改进方法。导管对于心脏手术特别有用。多通道导管最好使用挤出成型技术制备。

4. 发明授权

US08123668B2 Signal transmitting and lesion excluding heart implants for pacing defibrillating and/or sensing of heart beat 有权
标题翻译：信号传输和病变除心脏植入物用于起搏除颤和/或感觉心跳
公开(公告)号：US08123668B2
公开(公告)日：2012-02-28
申请号：US11536553
申请日：2006-09-28
申请人： Lon S. Annest , Arthur A. Bertolero , David K. Swanson
发明人： Lon S. Annest , Arthur A. Bertolero , David K. Swanson
IPC分类号： A61N1/362
CPC分类号： A61B17/12122 , A61B17/1215 , A61F2/2487 , A61N1/057 , A61N1/3627 , A61N1/3956 , A61N1/3987
摘要： Devices, systems, and methods for treating a heart of a patient may make use of structures which limit a size of a chamber of the heart, such as by deploying a tensile member to bring a wall of the heart toward (optionally into contact with) a septum of the heart. The implant may include an electrode or other structure for applying pacing signals to one or both ventricles of the heart, for defibrillating the heart, for sensing beating of the heart or the like. A wireless telemetry and control system may allowing the implant to treat congestive heart failure, monitor the results of the treatment, and apply appropriate electrical stimulation.
摘要翻译：用于治疗患者心脏的装置，系统和方法可以利用限制心脏室的尺寸的结构，例如通过展开拉伸构件以将心脏的壁朝向（任选地接触）心脏隔膜植入物可以包括用于将起搏信号施加到心脏的一个或两个心室的电极或其他结构，用于使心脏去纤颤，用于感测心脏的跳动等。无线遥测和控制系统可以允许植入物治疗充血性心力衰竭，监测治疗结果，并施加适当的电刺激。

5. 发明申请

US20110230903A1 METHODS AND DEVICES FOR MINIMALLY INVASIVE CARDIAC SURGERY FOR ATRIAL FIBRILLATION 审中-公开
标题翻译：用于急性心肌梗死的最小入路心脏手术的方法和装置
公开(公告)号：US20110230903A1
公开(公告)日：2011-09-22
申请号：US13117863
申请日：2011-05-27
申请人： Arthur A. Bertolero
发明人： Arthur A. Bertolero
IPC分类号： A61B17/08
CPC分类号： A61B1/12 , A61B5/04 , A61B18/14 , A61B2017/00243 , A61B2017/22051 , A61B2018/00351 , A61B2018/00982
摘要： Devices for enhancing minimally invasive cardiac surgery include a visualization device including an inflatable balloon at or near the distal end. Some visualization devices also include one or more lumens for allowing the introduction of one or more devices to a surgical site through the visualization device. Systems of the invention involve a visualization device which has at least one lumen for allowing introduction of an ablation device and/or other devices. A visualization device with an inflatable balloon may be positioned to create a space between a heart and pericardium when the balloon is inflated.
摘要翻译：用于增强微创心脏手术的装置包括可视化装置，其包括在远端处或附近的可充气气囊。一些可视化装置还包括用于允许通过可视化装置将一个或多个装置引入手术部位的一个或多个流明。本发明的系统涉及一种可视化装置，其具有用于允许引入消融装置和/或其它装置的至少一个内腔。具有可膨胀气囊的可视化装置可以被定位成在气囊膨胀时在心脏和心包之间产生空间。

6. 发明授权

US07951069B2 Methods and devices for minimally invasive cardiac surgery for atrial fibrillation 有权
标题翻译：用于心房颤动的微创心脏手术的方法和装置
公开(公告)号：US07951069B2
公开(公告)日：2011-05-31
申请号：US12273938
申请日：2008-11-19
申请人： Arthur A. Bertolero
发明人： Arthur A. Bertolero
IPC分类号： A61B1/04
CPC分类号： A61B1/12 , A61B5/04 , A61B18/14 , A61B2017/00243 , A61B2017/22051 , A61B2018/00351 , A61B2018/00982
摘要： Devices for enhancing minimally invasive cardiac surgery include a visualization device including an inflatable balloon at or near the distal end. Some visualization devices also include one or more lumens for allowing the introduction of one or more devices to a surgical site through the visualization device. Systems of the invention involve a visualization device which has at least one lumen for allowing introduction of an ablation device and/or other devices. A visualization device with an inflatable balloon may be positioned to create a space between a heart and pericardium when the balloon is inflated.
摘要翻译：用于增强微创心脏手术的装置包括可视化装置，其包括在远端处或附近的可充气气囊。一些可视化装置还包括用于允许通过可视化装置将一个或多个装置引入手术部位的一个或多个流明。本发明的系统涉及一种可视化装置，其具有用于允许引入消融装置和/或其它装置的至少一个内腔。具有可膨胀气囊的可视化装置可以被定位成在气囊膨胀时在心脏和心包之间产生空间。

7. 发明授权

US07931579B2 Tissue positioner 有权
标题翻译：组织定位器
公开(公告)号：US07931579B2
公开(公告)日：2011-04-26
申请号：US11512796
申请日：2006-08-29
申请人： Arthur A. Bertolero , Tamer Ibrahim
发明人： Arthur A. Bertolero , Tamer Ibrahim
IPC分类号： A61F13/00
CPC分类号： A61B17/0206 , A61B2017/0237 , A61B2017/308
摘要： Apparatus and methods for stabilizing and/or positioning tissues or organs during surgical procedures. One feature of the positioners of the invention includes the use of one or more suction elements used to grip the organ or tissue. The main body of the suction element comprises body defining a polyhedral shaped chamber, an elliptical ring structure and a vacuum port. The invention further includes structures to support the suction element and hold the suction element and attached tissue in a fixed position including catheters, lockable flexible arms, and retractors.
摘要翻译：用于在外科手术过程中稳定和/或定位组织或器官的装置和方法。本发明的定位器的一个特征包括使用一个或多个用于夹紧器官或组织的抽吸元件。抽吸元件的主体包括限定多面体形状的室，椭圆环结构和真空端口的主体。本发明还包括用于支撑抽吸元件并将抽吸元件和附着的组织保持在包括导管，可锁定的柔性臂和牵开器的固定位置的结构。

8. 发明授权

US07879003B2 Multichannel catheter with obturator 有权
标题翻译：带通孔的多通道导管
公开(公告)号：US07879003B2
公开(公告)日：2011-02-01
申请号：US11029820
申请日：2005-01-03
申请人： Arthur A. Bertolero , Raymond S. Bertolero , Jerome B. Riebman
发明人： Arthur A. Bertolero , Raymond S. Bertolero , Jerome B. Riebman
IPC分类号： A61M29/00
CPC分类号： A61M25/003 , A61M25/0032 , A61M25/007 , A61M25/10 , A61M2025/0031 , A61M2025/1052
摘要： A multichannel catheter for extracorporeal circulation of blood to a patient undergoing cardiovascular treatments or surgery has three independent channels, an obturator and an expandable balloon. The first channel is the largest and is of a size that allows for delivery of blood through outlet parts in the wall of the first channel to a patient in an amount sufficient to maintain the patient's metabolism and perfusion throughout the treatment or surgery. The obturator is longitudinally insertable into the first channel. The second and third channels are integrated into the wall of the first channel. The second channel is suitable for delivering a biologically active fluid to the heart and/or venting the left heart. The third channel is suitable for delivering a fluid to the balloon for its expansion. The catheter provides an improved means of preparing for or performing cardiovascular surgery on a patient using a cardiopulmonary machine for extracorporeal circulation of blood.
摘要翻译：用于体外血液循环到经历心血管治疗或手术的患者的多通道导管具有三个独立的通道，一个闭孔器和一个可扩张的气囊。第一个通道是最大的，并且具有允许通过第一通道的壁中的出口部分向患者输送足以在整个治疗或手术中维持患者的新陈代谢和灌注的量的尺寸。封闭器可纵向插入第一通道。第二和第三通道被集成到第一通道的壁中。第二通道适于将生物活性流体输送到心脏和/或排出左心脏。第三个通道适用于将流体输送到球囊进行扩张。该导管提供了一种用于使用心肺机器进行血液体外循环来为患者准备或进行心血管手术的改进方法。

9. 发明申请

US20110009853A1 LEFT ATRIAL APPENDAGE DEVICES AND METHODS 审中-公开
标题翻译：左边的附件设备和方法
公开(公告)号：US20110009853A1
公开(公告)日：2011-01-13
申请号：US12886436
申请日：2010-09-20
申请人： Arthur A. Bertolero , Tamer Ibrahim , Steve Geyster
发明人： Arthur A. Bertolero , Tamer Ibrahim , Steve Geyster
IPC分类号： A61B18/20 , A61B17/08 , A61B17/10 , A61B18/18
CPC分类号： A61B17/083 , A61B17/0057 , A61B17/068 , A61B17/08 , A61B17/122 , A61B17/1285 , A61B17/320016 , A61B2017/00243
摘要： Devices and methods for clamping tissue and/or moving two tissue structures together by moving two plates or arm together. The pressure or force applied to the tissue may be used to bring the tissue together, to seal an opening or to cut through and remove a portion of the tissue. In one procedure disclosed, a clip applier may be used to apply one or more clips to the left atrial appendage of the heart to prevent clots from the left atrial appendage from embolizing and causing harm to the patient, such as a stroke.
摘要翻译：通过将两个板或臂一起移动来夹紧组织和/或移动两个组织结构在一起的装置和方法。施加到组织的压力或力可以用于将组织带到一起，以密封开口或切割并去除组织的一部分。在所公开的一个程序中，施夹器可用于将一个或多个夹子应用于心脏的左心耳，以防止左心耳附近的血栓栓塞并对患者造成伤害，例如中风。

10. 发明授权

US07846129B2 Multichannel catheter 失效
标题翻译：多通道导管
公开(公告)号：US07846129B2
公开(公告)日：2010-12-07
申请号：US11132916
申请日：2005-05-18
申请人： Arthur A. Bertolero , Raymond S. Bertolero , Jerome B. Riebman
发明人： Arthur A. Bertolero , Raymond S. Bertolero , Jerome B. Riebman
IPC分类号： A61M29/00
CPC分类号： A61B17/29 , A61B1/05 , A61B1/313 , A61B17/00234 , A61B17/0206 , A61B17/2812 , A61B17/320016 , A61B17/8085 , A61B46/10 , A61B90/36 , A61B90/37 , A61B90/50 , A61B2017/00199 , A61B2017/00243 , A61B2017/0046 , A61B2017/00557 , A61B2017/2904 , A61B2017/2905 , A61B2017/2946 , A61M1/3659 , A61M25/0029 , A61M25/003 , A61M25/0032 , A61M25/10 , A61M25/1027 , A61M2025/0031 , A61M2025/1052 , A61M2025/1086 , A61M2025/1097 , A61M2210/127
摘要： A single, multichannel catheter for extracorporeal circulation of blood to a patient undergoing cardiac treatments or surgery. The catheter has three independent channels and an expandable balloon. The first channel is the largest and delivers blood to a patient to maintain the patient's metabolism and perfusion throughout the treatment or surgery. A second, smaller channel is integrated into the wall of the first channel and delivers a biologically active fluid (e.g., for cardioplegia) to the heart and/or venting the left heart. A third, smaller channel is integrated into the wall of the first channel, and delivers an expansion fluid to the balloon to occlude the flow of blood to the heart. Preferably, the first channel accounts for at least about 70% of the total channel volume. The multichannel catheter is best prepared using an extrusion molding technique.
摘要翻译：一种用于体外循环血液的单通道导管，用于接受心脏治疗或手术的患者。导管具有三个独立的通道和可扩张的气囊。第一个通道是最大的，并向患者输送血液，以在整个治疗或手术中维持患者的新陈代谢和灌注。第二个更小的通道被集成到第一通道的壁中并将生物活性流体（例如，用于心麻痹）递送到心脏和/或排出左心脏。第三个更小的通道被集成到第一通道的壁中，并且将膨胀流体输送到气囊以将血流封闭到心脏。优选地，第一通道占总通道容积的至少约70％。多通道导管最好使用挤出成型技术制备。

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