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81. 发明授权

US5057537A Ortho-substituted 1-naphthyl ethers and fungicides containing these 失效
标题翻译： ORTHO取代的1-NTHTHYL ETHERS和含有这些的杀真菌剂
公开(公告)号：US5057537A
公开(公告)日：1991-10-15
申请号：US474506
申请日：1990-02-02
申请人： Bernd Wenderoth , Hubert Sauter , Albrecht Harreus , Franz Roehl , Eberhard Ammermann , Gisela Lorenz
发明人： Bernd Wenderoth , Hubert Sauter , Albrecht Harreus , Franz Roehl , Eberhard Ammermann , Gisela Lorenz
IPC分类号： A01N37/10 , A01N37/38 , A01N37/44 , A01N37/50 , C07C69/734 , C07C205/37 , C07C251/48 , C07C255/54 , C07C323/12 , C07C323/19 , C07C323/20
CPC分类号： C07C251/48 , A01N37/38 , A01N37/50 , C07C323/12 , C07C323/19
摘要： Ortho-substituted 1-napthyl ethers of the formula ##STR1## where X is CH or N, Y is saturated or unsaturated alkylene and R is aryl, aryloxy, arylthio or arylalkoxy, the aromatic ring being substituted or unsubstituted, and fungicides containing these compounds.
摘要翻译：式（I）的正取代的1-萘基醚，其中X是CH或N，Y是饱和或不饱和的亚烷基，R是芳基，芳氧基，芳硫基或芳基烷氧基，芳环是取代或未取代的，杀真菌剂含有这些化合物。

82. 发明授权

US4880870A Polymer granulate, a process for its preparation, and its use 失效
标题翻译：聚合物颗粒，其制备方法及其用途
公开(公告)号：US4880870A
公开(公告)日：1989-11-14
申请号：US762746
申请日：1985-07-30
申请人： Wolfgang Zimmermann , Albrecht Harreus
发明人： Wolfgang Zimmermann , Albrecht Harreus
IPC分类号： C09D5/03 , C08F16/02 , C08F16/06 , C08J3/05 , C08J3/12 , C09D129/04 , C09J11/00 , C09J129/04 , C09J201/00
CPC分类号： C08J3/05 , C08J3/124 , C08J2300/14 , C08J2329/04 , Y10T428/2991 , Y10T428/2995 , Y10T428/2998
摘要： A polymer granulate whose particles consist of a core component and a coating component can be prepared by mixing a granular polymer with a pulverulent coating agent. The core component is made of a water-soluble polymer, in particular a polyvinyl alcohol. The coating component is a water-soluble or water-insoluble substance which is applied to the water-moistened particles of the core component. The particles of the polymer granulate have diameters within the range from 0.6 to 6 mm. The granulate has particularly good freeflowing properties; it is especially suitable for preparing adhesives.
摘要翻译：可以通过将粒状聚合物与粉末涂料混合来制备颗粒由核心组分和涂层组分组成的聚合物颗粒。核心部件由水溶性聚合物，特别是聚乙烯醇制成。涂层组分是水溶性或水不溶性物质，其被施加到核心组分的水润湿颗粒上。聚合物颗粒的颗粒的直径在0.6至6mm的范围内。颗粒具有特别好的自由流动性; 它特别适用于制备粘合剂。

83. 发明授权

US4732900A 1,2,4-triazolo-carbamates 失效
标题翻译： 1,2,4-三唑并 - 氨基甲酸酯
公开(公告)号：US4732900A
公开(公告)日：1988-03-22
申请号：US791184
申请日：1985-10-25
申请人： Karl-Heinz Weber , Dieter Hinzen , Franz-Josef Kuhn , Erich Lehr , Wilhelm Frolke , Wolfgang Troger , Helmut Ensinger , Gerhard Walther , Albrecht Harreus
发明人： Karl-Heinz Weber , Dieter Hinzen , Franz-Josef Kuhn , Erich Lehr , Wilhelm Frolke , Wolfgang Troger , Helmut Ensinger , Gerhard Walther , Albrecht Harreus
IPC分类号： A61K31/41 , A61K31/4196 , A61K31/44 , A61K31/4427 , A61K31/445 , A61P21/00 , A61P25/02 , A61P25/20 , A61P25/26 , A61P25/28 , C07D213/74 , C07D249/12 , C07D401/04 , C07D401/14 , C07D401/12
CPC分类号： C07D213/74 , C07D249/12 , C07D401/04
摘要： New 1,2,4-triazolo-carbamates of general formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the meanings given in the specification, are acetylcholinesterase inhibitors and may be used as drugs for the treatment of senile dementia.
摘要翻译：通式为“IMAGE”I的新的1,2,4-三唑并 - 氨基甲酸酯其中R1，R2，R3和R4具有说明书中给出的含义，是乙酰胆碱酯酶抑制剂，可用作治疗老年痴呆的药物。

84. 发明授权

US4623646A PAF-antagonistic diazepines, methods of use 失效
标题翻译： PAF拮抗二氮杂，使用方法
公开(公告)号：US4623646A
公开(公告)日：1986-11-18
申请号：US782648
申请日：1985-10-01
申请人： Jorge Casals-Stenzel , Karl-Heinz Weber , Gerhard Walther , Albrecht Harreus , Gojko Muacevic
发明人： Jorge Casals-Stenzel , Karl-Heinz Weber , Gerhard Walther , Albrecht Harreus , Gojko Muacevic
IPC分类号： C07D495/04 , A61K31/55 , A61P7/02 , A61P11/08 , A61P43/00 , C07D243/12 , C07D471/04 , C07D487/04 , C07D495/14 , C07D513/04
CPC分类号： A61K31/55
摘要： The invention discloses a method of treating an individual having a disorder responsive to PAF-antagonist activity by treating the individual with a compound of formula I. ##STR1## wherein A is an anellated and optionally substituted benzene or 5- or 6- membered heterocyclic ring; R.sub.5 and Z are each independently hydrogen or an optionally substituted C.sub.1 -C.sub.8 alkyl, alkenyl or alkynyl; R.sub.6 is an optionally substituted phenyl, or is thienyl or .alpha.-pyridyl; Y is ##STR2## and nontoxic, pharmaceutically acceptable acid addition salts thereof.
摘要翻译：本发明公开了一种通过用式I化合物处理个体来治疗患有对PAF-拮抗剂活性有反应作用的病症的个体的方法。其中A是一种有一定义的任选取代的苯或5-或6-元杂环 ; R 5和Z各自独立地为氢或任选取代的C 1 -C 8烷基，烯基或炔基; R6是任选取代的苯基，或是噻吩基或α-吡啶基; Y是及其无毒的药学上可接受的酸加成盐。

85. 发明授权

US4621083A PAF-antagonistic diazepines 失效
标题翻译： PAF拮抗二氮杂
公开(公告)号：US4621083A
公开(公告)日：1986-11-04
申请号：US782632
申请日：1985-10-01
申请人： Jorge Casals-Stenzel , Karl-Heinz Weber , Gerhard Walther , Albrecht Harreus , Gojko Muacevic
发明人： Jorge Casals-Stenzel , Karl-Heinz Weber , Gerhard Walther , Albrecht Harreus , Gojko Muacevic
IPC分类号： C07D495/04 , A61K31/55 , A61P7/02 , A61P11/00 , A61P11/08 , A61P37/08 , A61P43/00 , C07D487/04 , C07D487/14 , C07D495/14 , C07D495/22 , C07D513/14 , A61K31/65
CPC分类号： A61K31/55
摘要： The invention discloses a method of treating an individual having a disorder responsive to PAF-antagonist activity by treating the individual with a compound of formula I or II: ##STR1## wherein A is an annealed and optionally substituted benzene or 5- or 6-membered heterocyclic ring; B is an optionally substituted 5-membered heterocyclic ring; R.sub.5 and R.sub.7 are each independently hydrogen or an optionally substituted C.sub.1 -C.sub.8 alkyl, alkenyl or alkynyl; R.sub.6 is an optionally substituted phenyl, or is thienyl or .alpha.-pyridyl; and non-toxic, pharmaceutically acceptable acid addition salts thereof.
摘要翻译：本发明公开了通过用式I或II化合物处理个体来治疗患有对PAF-拮抗剂活性有反应作用的病症的个体的方法：其中A是退火和任选取代的苯或5-或6-元杂环 B是任选取代的5元杂环; R 5和R 7各自独立地为氢或任选取代的C 1 -C 8烷基，烯基或炔基; R6是任选取代的苯基，或是噻吩基或α-吡啶基; 及其无毒的药学上可接受的酸加成盐。

86. 发明授权

US4323492A Plasticizer containing polyvinyl alcohol granules 失效
标题翻译：含增塑剂的聚乙烯醇颗粒
公开(公告)号：US4323492A
公开(公告)日：1982-04-06
申请号：US211627
申请日：1980-12-01
申请人： Wolfgang Zimmermann , Albrecht Harreus
发明人： Wolfgang Zimmermann , Albrecht Harreus
IPC分类号： C08L29/00 , C08J3/12 , C08J3/16 , C08J3/18 , C08K5/00 , C08K5/05 , C08L29/02 , C08L29/04 , C08K3/18
CPC分类号： C08J3/18 , C08J3/12 , C08K5/0016 , C08J2329/04
摘要： For the thermoplastic processing of polyvinyl alcohol, the processing temperature must be below the decomposition temperature of the polyvinyl alcohol; this is attained by incorporating plasticizers. For preparing a plasticizer-containing granular polyvinyl alcohol wherein the plasticizer is homogeneously distributed, there is used as starting material a granular polyvinyl alcohol consisting substantially of particles having a definite diameter. The plasticizer is incorporated in the presence of a small amount of water insufficient to dissolve the polyvinyl alcohol, and the temperature is adjusted in a definite manner during the mixing operation. Simultaneous presence of fine particles of a high molecular weight organic compound soluble or dispersible in water is advantageous. The plasticizer-containing granular polyvinyl alcohol is suitable for the manufacture of any shaped articles, especially films and sheets.
摘要翻译：对于聚乙烯醇的热塑性加工，加工温度必须低于聚乙烯醇的分解温度; 这是通过加入增塑剂来实现的。为了制备含增塑剂的粒状聚乙烯醇，其中增塑剂均匀分布，用作基本上由具有一定直径的颗粒组成的颗粒状聚乙烯醇作为原料。在不足以溶解聚乙烯醇的少量水的存在下引入增塑剂，并且在混合操作期间以一定的方式调节温度。同时存在可溶于或可分散在水中的高分子量有机化合物的细颗粒是有利的。含增塑剂的颗粒状聚乙烯醇适用于任何成型制品，特别是薄膜和片材的制造。

87. 发明授权

US3984494A Graft copolymers of vinyl acetate on polyethylene oxide as self-supporting capsules 失效
标题翻译：乙酸乙烯酯在聚环氧乙烷上的接枝共聚物作为自支撑胶囊
公开(公告)号：US3984494A
公开(公告)日：1976-10-05
申请号：US534279
申请日：1974-12-19
申请人： Albrecht Harreus , Wolfgang Zimmermann
发明人： Albrecht Harreus , Wolfgang Zimmermann
IPC分类号： C08F8/00 , A61K9/00 , A61K9/48 , C08F8/12 , C08F283/00 , C08F283/06 , C08L31/04 , B01J13/00
CPC分类号： A61K9/4816
摘要： An encapsulating material for drugs consisting of a modified polyvinyl alcohol which is a partially hydrolized graft copolymer of vinyl acetate on polyethylene oxide.
摘要翻译：一种由改性聚乙烯醇组成的药物的包封材料，其是乙酸乙烯酯在聚环氧乙烷上的部分水解的接枝共聚物。

88. 发明授权

US06989453B2 Method of producing a cyclohexenone oxime ether lithium salt, products which can be obtained using this method, the use thereof and corresponding plant protection agents 失效
标题翻译：制备环己烯酮肟醚锂盐的方法，可以使用该方法得到的产物，其用途和相应的植物保护剂
公开(公告)号：US06989453B2
公开(公告)日：2006-01-24
申请号：US10380107
申请日：2001-09-12
申请人： Volker Maywald , Reiner Kober , Frank Heimann , Klaus Oberdorf , Albrecht Harreus , Norbert Götz , Marcus Vossen
发明人： Volker Maywald , Reiner Kober , Frank Heimann , Klaus Oberdorf , Albrecht Harreus , Norbert Götz , Marcus Vossen
IPC分类号： C07D335/00
CPC分类号： C07D335/02
摘要： A process for preparing 2-{1-[2-(4-chlorophenoxy)propoxyimino]-butyl}-3-hydroxy-5-(tetrahydrothiopyran-3-yl)cyclohex-2-enone lithium salt by reacting the corresponding acid 2-{1-[2-(4-chlorophenoxy)-propoxyimino]butyl}-3-hydroxy-5-(tetrahydrothiopyran-3-yl)-cyclohex-2-enone and lithium hydroxide and the isolation of the lithium salt are described. Here, it is advantageous to use a solvent mixture which comprises methanol and at least one aromatic hydrocarbon and to remove at least some of the solvent prior to the isolation. It is particularly preferred to dissolve the acid in an aromatic hydrocarbon, preferably toluene, and to use a methanolic lithium hydroxide solution.The product, which can be obtained in a more efficient manner by this process, furthermore has considerable advantages with respect to formulation.
摘要翻译：通过使相应的酸2-（1-（2-氯苯氧基）丙氧基亚氨基] - 丁基} -3-羟基-5-（四氢噻喃-3-基）环己-2-烯酮锂盐描述了{1- [2-（4-氯苯氧基） - 丙氧基亚氨基]丁基} -3-羟基-5-（四氢噻喃-3-基） - 环己-2-烯酮和氢氧化锂并分离了锂盐。这里，使用包含甲醇和至少一种芳烃的溶剂混合物是有利的，并且在分离之前除去至少一些溶剂。特别优选将酸溶解在芳族烃，优选甲苯中，并使用甲醇氢氧化锂溶液。通过该方法可以以更有效的方式获得的产品在制剂方面还具有相当大的优点。

89. 发明授权

US06509379B1 Phenylacetic acid derivatives, process and intermediate products for their preparation, and their use as fungicides and pesticides 失效
标题翻译：苯乙酸衍生物，其制备方法和中间产物，并用作杀真菌剂和杀虫剂
公开(公告)号：US06509379B1
公开(公告)日：2003-01-21
申请号：US09051996
申请日：1998-04-23
申请人： Herbert Bayer , Hubert Sauter , Klaus Oberdorf , Wassilios Grammenos , Thomas Grote , Reinhard Kirstgen , Bernd Müller , Ruth Müller , Franz Röhl , Eberhard Ammermann , Volker Harries , Gisela Lorenz , Siegfried Strathmann , Norbert Götz , Albrecht Harreus
发明人： Herbert Bayer , Hubert Sauter , Klaus Oberdorf , Wassilios Grammenos , Thomas Grote , Reinhard Kirstgen , Bernd Müller , Ruth Müller , Franz Röhl , Eberhard Ammermann , Volker Harries , Gisela Lorenz , Siegfried Strathmann , Norbert Götz , Albrecht Harreus
IPC分类号： A01N3734
CPC分类号： C07C251/60
摘要： Phenylacetic acid derivatives of the formula I where the variables are as disclosed herein, their salts, processes and intermediates for their preparation, and their use for controlling harmful fungi and animal pests.
摘要翻译：式I的苯乙酸衍生物，其中变量如本文所公开，其盐，其制备方法和中间体及其用于控制有害真菌和动物害虫的用途。

90. 发明授权

US06323154B1 3-aryluracils and intermediates for their preparation 失效
标题翻译： 3-芳基尿嘧啶及其制备中间体
公开(公告)号：US06323154B1
公开(公告)日：2001-11-27
申请号：US08894749
申请日：1997-08-26
申请人： Ralf Klintz , Norbert Götz , Peter Schäfer , Gerhard Hamprecht , Elisabeth Heistracher , Christoph-Sweder von dem Bussche-Hünnefeld , Albrecht Harreus , Karl-Otto Westphalen , Helmut Walter , Ulf Misslitz
发明人： Ralf Klintz , Norbert Götz , Peter Schäfer , Gerhard Hamprecht , Elisabeth Heistracher , Christoph-Sweder von dem Bussche-Hünnefeld , Albrecht Harreus , Karl-Otto Westphalen , Helmut Walter , Ulf Misslitz
IPC分类号： C07D41310
CPC分类号： C07D241/52 , A01N43/60 , A01N43/84 , C07D241/54 , C07D265/36 , C07D403/04 , C07D413/04
摘要： 3-Aryluracils of the formula I wherein A is hydrogen, methyl or amino; X is oxygen or —N(R7)— (R7=H alkyl, alkenyl, alkynyl, alkylcarbonyl or alkoxyalkyl); Y1 is oxygen or sulfur; Z is oxygen or —N(R8)— (R8=H, alkyl, alkenyl, alkynyl or alkoxyalkyl); R1 is hydrogen or halogen; R2 is hydrogen, halogen, alkyl, haloalkyl, alkylthio, alkylsulfenyl or alkylsulfonyl; R3 is hydrogen, halogen or alkyl; R4 is hydrogen; or optionally substituted alkyl, cycloalkyl, haloalkyl, alkenyl, alkynyl, alkylcarbonyl, alkenylcarbonyl, alkynylcarbonyl or alkylsulfonyl, R5, R6 are hydrogen, alkyl, alkenyl, alkynyl or alkoxyalkyl; or R6, R8 are together a second chemical bond, methods and intermediates for their manufacture, and their use as herbicides or for the desiccation or defoliation of plants.
摘要翻译：式I其中A是氢，甲基或氨基; 3-是氧或-N（R 7） - （R 7 = H烷基，烯基，炔基，烷基羰基或烷氧基烷基）; Y 1是氧或硫; Z是氧或 - N（R8） - （R8 = H，烷基，烯基，炔基或烷氧基烷基）; R1是氢或卤素; R2是氢，卤素，烷基，卤代烷基，烷硫基，烷基亚磺酰基或烷基磺酰基; R3是氢，卤素或烷基; R4 是氢; 或任选取代的烷基，环烷基，卤代烷基，烯基，炔基，烷基羰基，烯基羰基，炔基羰基或烷基磺酰基，R5，R6是氢，烷基，烯基，炔基或烷氧基烷基; 或R6，R8一起是第二化学键，其制造方法和中间体，以及它们作为除草剂的用途或用于植物的干燥或脱叶。

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