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71. 发明申请

US20140326600A1 CARBON NANOSTRUCTURE ELECTROCHEMICAL SENSOR AND METHOD 审中-公开
标题翻译：碳纳米结构电化学传感器及方法
公开(公告)号：US20140326600A1
公开(公告)日：2014-11-06
申请号：US14344025
申请日：2012-09-11
申请人： Chunhong Li , David J. Ruggieri
发明人： Chunhong Li , David J. Ruggieri
IPC分类号： G01N27/30 , G01N27/414
CPC分类号： G01N27/414 , B82Y30/00 , B82Y40/00 , C01B32/174 , G01N27/302 , G01N27/308 , G01N27/3271 , G01N27/4146 , G01N33/48707
摘要： Carbon nanostructures may be protected and functionalized using a layer-by-layer method whereby functional groups on the carbon nanostructure surface may be further derivatized to incorporate additional functional moieties. Carbon nanostructures functionalized using such a layer-by-layer method may be used to disperse, sort, separate and purify carbon nanostructures and may be used as sensing elements such as voltammetric, amperometric, and potentiometric pH sensors or as biometric sensing elements and electrodes and intracorporeal sensors and electrodes.
摘要翻译：可以使用逐层方法来保护和官能化碳纳米结构，由此碳纳米结构表面上的官能团可被进一步衍生化以引入额外的官能部分。使用这种逐层方法功能化的碳纳米结构可以用于分散，分类，分离和净化碳纳米结构，并且可以用作感测元件，例如伏安法，电流计和电位pH传感器，或者用作生物测定元件和电极，体内传感器和电极。

72. 发明授权

US08877037B2 Device for providing a means for internal calibration in an electrochemical sensor 有权
标题翻译：用于在电化学传感器中提供用于内部校准的装置的装置
公开(公告)号：US08877037B2
公开(公告)日：2014-11-04
申请号：US13255224
申请日：2010-03-10
申请人： Joseph A. Duimstra , Lee Leonard , Gregory G. Wildgoose , Eric Lee
发明人： Joseph A. Duimstra , Lee Leonard , Gregory G. Wildgoose , Eric Lee
IPC分类号： C25B11/00 , G01N27/30 , G01N27/333 , B82Y30/00 , G01N27/36
CPC分类号： G01N27/302 , B82Y30/00 , C25B11/00 , G01N27/301 , G01N27/333 , G01N27/36 , Y10S977/742
摘要： Internally calibrated pH and other analyte sensors based on redox agents provide more accurate results when the redox active reference agent is in a constant chemical environment, yet separated from the solution being analyzed in such a way as to maintain electrical contact with the sample. Room temperature ionic liquids (RTIL) can be used to achieve these results when used as a salt bridge between the reference material and the sample being analyzed. The RTIL provides the constant chemical environment and ionic strength for the redox active material (RAM) and provides an electrolytic layer that limits or eliminates direct chemical interaction with the sample. A broad range of RAMs can be employed in a variety of configurations in such “Analyte Insensitive Electrode” devices.
摘要翻译：当氧化还原活性参考试剂处于恒定的化学环境中时，内部校准的pH值和其它基于氧化还原剂的分析物传感器可提供更精确的结果，但与被分析的溶液分离，以保持与样品的电接触。当用作参考物质和正在分析的样品之间的盐桥时，室温离子液体（RTIL）可用于实现这些结果。 RTIL为氧化还原活性材料（RAM）提供恒定的化学环境和离子强度，并提供限制或消除与样品的直接化学相互作用的电解质层。在这种“分析物不敏感电极”装置中，可以采用各种各样的配置的宽范围的RAM。

73. 发明申请

US20140190825A1 pH Sensor 审中-公开
公开(公告)号：US20140190825A1
公开(公告)日：2014-07-10
申请号：US14045526
申请日：2013-10-03
申请人： Digital Concepts of Missouri, Inc.
发明人： Michael D. Mosley , Paul Decker
IPC分类号： G01N27/404 , G01N27/416
CPC分类号： G01N27/302 , G01N27/301 , G01N27/404 , G01N27/4167
摘要： Improvements in references electrodes, halogen sensors, pH sensors, TDS sensors, combinations thereof, and related methods.

74. 发明授权

US08742470B2 pH sensor and manufacturing method 有权
标题翻译： pH传感器和制造方法
公开(公告)号：US08742470B2
公开(公告)日：2014-06-03
申请号：US13600385
申请日：2012-08-31
申请人： Matthias Merz , Coenraad Cornelis Tak , Romano Hoofman
发明人： Matthias Merz , Coenraad Cornelis Tak , Romano Hoofman
IPC分类号： G01N27/403
CPC分类号： G01N27/302 , G01N27/4148 , G01N27/4167 , G01N33/02 , G01N33/04 , G01N33/12 , H01L2224/48091 , H01L2924/1815 , Y10T29/49002 , H01L2924/00014
摘要： Disclosed is a pH sensor comprising a carrier (10) comprising a plurality of conductive tracks and an exposed conductive area (40) defining a reference electrode connected to one of said conductive tracks; a sensing device (30) mounted on the carrier and connected at least one other of said conductive tracks; an encapsulation (20) covering the carrier, said encapsulation comprising a first cavity (22) exposing a surface (32) of the sensing device and a second cavity (24) exposing the exposed conductive area, said second cavity comprising a reference electrode material (42) and an ion reservoir material (44) sharing at least one ion type with said reference electrode material, the reference electrode material being sandwiched between the exposed conductive area and the ion reservoir material. A method of manufacturing such a pH sensor is also disclosed.
摘要翻译：公开了一种pH传感器，其包括包括多个导电轨道的载体（10）和限定连接到所述导电轨道之一的参考电极的暴露导电区域（40）感测装置（30），其安装在所述载体上并且连接至少另一个所述导电轨道; 覆盖所述载体的封装（20），所述封装包括暴露所述感测装置的表面（32）的第一空腔（22）和暴露所述暴露的导电区域的第二空腔（24），所述第二空腔包括参考电极材料 42）和与所述参考电极材料共享至少一种离子型离子储存器材料（44），所述参考电极材料夹在所述暴露的导电区域和所述离子储存器材料之间。还公开了制造这种pH传感器的方法。

75. 发明申请

US20140090978A1 POTENTIOMETRIC SENSOR 有权
标题翻译：电位传感器
公开(公告)号：US20140090978A1
公开(公告)日：2014-04-03
申请号：US14041715
申请日：2013-09-30
申请人： Invensys Systems Inc.
发明人： Daniel G. Tower, III , Steven J. West , Michael Mason Bower , Jose L. Pestana , Zhisheng Sun , Stephen B. Talutis
IPC分类号： G01N27/30
CPC分类号： G01N27/302 , G01N27/36 , G01N27/4035
摘要： A potentiometric sensor includes an elongate non-glass, non-metal housing having opposite first and second longitudinal ends and a length extending between the first and second longitudinal ends. The housing defines a lumen extending along the length of the housing. A measuring half-cell assembly is received in the lumen of the housing and secured to the housing. The measuring half-cell assembly includes a glass body having opposite first and second longitudinal ends and a length extending between the first and second ends of the glass body. The second longitudinal end of the glass body is adjacent the second longitudinal end of the housing and a longitudinal extent of the glass body is less than the length of the housing.
摘要翻译：电位传感器包括具有相对的第一和第二纵向端部以及在第一和第二纵向端部之间延伸的长度的细长非玻璃非金属壳体。壳体限定沿着壳体的长度延伸的内腔。测量半电池组件被容纳在壳体的内腔中并固定到壳体上。测量半电池组件包括具有相对的第一和第二纵向端部以及在玻璃体的第一和第二端之间延伸的长度的玻璃体。玻璃体的第二纵向端部与壳体的第二纵向端部相邻，并且玻璃体的纵向范围小于壳体的长度。

76. 发明申请

US20140027280A1 FAD-CONJUGATED GLUCOSE DEHYDROGENASE GENE 有权
标题翻译： FAD-结合葡萄糖脱氢酶基因
公开(公告)号：US20140027280A1
公开(公告)日：2014-01-30
申请号：US13920445
申请日：2013-06-18
申请人： Ikeda Food Research Co., Ltd
发明人： Takako YADA , Koji MIYAMOTO , Michinari HONDA
IPC分类号： C12Q1/00
CPC分类号： C12N9/0006 , C12Q1/006 , C12Q1/32 , C12Q1/54 , C12Y101/9901 , G01N27/301 , G01N27/302 , G01N27/3271 , G01N33/66 , G01N2333/902 , G01N2333/904 , Y10T29/49117
摘要： Disclosed herein are a gene (polynucleotide) encoding an FAD-conjugated glucose dehydrogenase which can be characterized by reactivity to glucose, thermal stability, substrate-recognition performance, and low activity for maltose; a process for the production of the enzyme using a transformant cell transfected with the gene; a method for the determination of glucose; a reagent composition for use in the determination of glucose; and a biosensor for use in the determination of glucose. An embodiment is a polynucleotide encoding an FAD-conjugated glucose dehydrogenase, comprising a polypeptide whose amino acid sequence comprises X1-X2-X3-X4-X5-X6, wherein X1 and X2 independently represent an aliphatic amino acid residue; X3 and X6 independently represent a branched amino acid residue; and X4 and X5 independently represent a heterocyclic amino acid residue or an aromatic amino acid residue.
摘要翻译：本文公开了编码FAD-缀合的葡萄糖脱氢酶的基因（多核苷酸），其可以表征为对葡萄糖的反应性，热稳定性，底物识别性能和对麦芽糖的低活性; 使用用该基因转染的转化体细胞来生产酶的方法; 一种测定葡萄糖的方法; 用于测定葡萄糖的试剂组合物; 以及用于测定葡萄糖的生物传感器。一个实施方案是编码FAD-缀合的葡萄糖脱氢酶的多核苷酸，其包含其氨基酸序列包含X 1 -X 2 -X 3 -X 4 -X 5 -X 6的多肽，其中X 1和X 2独立地表示脂族氨基酸残基; X3和X6独立地表示支链氨基酸残基; X4和X5独立地表示杂环氨基酸残基或芳香族氨基酸残基。

77. 发明授权

US08551311B2 Ionic probe 有权
标题翻译：离子探针
公开(公告)号：US08551311B2
公开(公告)日：2013-10-08
申请号：US12249727
申请日：2008-10-10
申请人： John Robert Woodward , Pierre Antoine Robert Livrozet , Jean-Francois Maurice Rene Schvan , Russell Martin Young , Kevin James West
发明人： John Robert Woodward , Pierre Antoine Robert Livrozet , Jean-Francois Maurice Rene Schvan , Russell Martin Young , Kevin James West
IPC分类号： G01N27/26
CPC分类号： G01N27/302 , G01N27/36 , G01N27/4035
摘要： An ionic probe is provided according to the invention. The ionic probe includes an active electrode configured to generate a measurement signal for an external test fluid, a first reference electrode configured to generate a first reference signal, and an at least second reference electrode configured to generate at least a second reference signal. The measurement signal is compared to the first reference signal and the at least second reference signal in order to determine an ionic measurement of the external test fluid.
摘要翻译：根据本发明提供离子探针。离子探针包括被配置为产生用于外部测试流体的测量信号的有源电极，被配置为产生第一参考信号的第一参考电极以及被配置为产生至少第二参考信号的至少第二参考电极。将测量信号与第一参考信号和至少第二参考信号进行比较，以便确定外部测试流体的离子测量。

78. 发明申请

US20130248364A1 ELECTROCHEMICAL SENSORS 审中-公开
标题翻译：电化学传感器
公开(公告)号：US20130248364A1
公开(公告)日：2013-09-26
申请号：US13787534
申请日：2013-03-06
申请人： Sensor Innovations, Inc.
发明人： Carolyn R. Kahn , Elicia Wong , James A. Wilkins , Dean Mansour , Vern Norviel , Robbie Singh Sidhu
IPC分类号： G01N27/30
CPC分类号： G01N27/302 , G01N27/3335 , G01N27/4167 , Y02A90/26 , Y10T428/24421
摘要： Systems and methods are provided for detecting the presence of an analyte in a sample. A solid state electrochemical sensor can include a redox active moiety having an oxidation and/or reduction potential that is sensitive to the presence of an analyte immobilized over a surface of a working electrode. A redox active moiety having an oxidation and/or reduction potential that is insensitive to the presence of the analyte can be used for reference. Voltammetric measurements made using such systems can accurately determine the presence and/or concentration of the analyte in the sample. The solid state electrochemical sensor can be robust and not require calibration or re-calibration.
摘要翻译：提供了用于检测样品中分析物的存在的系统和方法。固态电化学传感器可以包括具有氧化和/或还原电位的氧化还原活性部分，其对固定在工作电极的表面上的分析物的存在敏感。具有对分析物的存在不敏感的氧化还原电位的氧化还原活性部分可以用作参考。使用这种系统进行的伏安测量可以准确地确定样品中分析物的存在和/或浓度。固态电化学传感器可以是鲁棒的，不需要校准或重新校准。

79. 发明申请

US20130153417A1 REFERENCE ELECTRODE 有权
标题翻译：参考电极
公开(公告)号：US20130153417A1
公开(公告)日：2013-06-20
申请号：US13819320
申请日：2011-08-25
申请人： Manabu Shibata , Yasukazu Iwamoto
发明人： Manabu Shibata , Yasukazu Iwamoto
IPC分类号： G01N27/30
CPC分类号： G01N27/302 , G01N27/301
摘要： A reference electrode for improving a product life cycle without using a gelled hydrophobic ionic liquid having a prescribed hardness or viscosity and without having a large thickness so as to be difficult to manufacture is provided. The reference electrode is provided with a housing for accommodating an internal electrode, a filler for electrically connecting the internal electrode, and a sample liquid. The filler is formed having a layer between the internal electrode and an opening formed in the housing for contacting the sample liquid and the filler. The filler includes a first layer including a water soluble electrolytic solution formed to be in contact with the internal electrode a second layer including a hydrophobic ionic liquid formed to be in contact with the first layer; and a third layer including a gelled hydrophobic ionic liquid formed in the opening so as to be in contact with the second layer.
摘要翻译：提供了一种用于改善产品寿命周期的参比电极，而不使用具有规定硬度或粘度并且不具有大厚度以致难以制造的凝胶状疏水性离子液体。参考电极设置有用于容纳内部电极的壳体，用于电连接内部电极的填充物和样品液体。填料形成在内部电极和形成在壳体中的开口之间的层，用于接触样品液体和填料。填料包括第一层，其包括形成为与内部电极接触的水溶性电解液，第二层包括形成为与第一层接触的疏水性离子液体; 以及第三层，其包括在所述开口中形成的与所述第二层接触的凝胶状疏水性离子液体。

80. 发明申请

US20120234696A1 ELECTRODES, SENSORS AND METHODS FOR MEASURING COMPONENTS IN WATER 有权
标题翻译：用于测量水中组分的电极，传感器和方法
公开(公告)号：US20120234696A1
公开(公告)日：2012-09-20
申请号：US13051106
申请日：2011-03-18
申请人： Michael D. Mosley , Paul Decker
发明人： Michael D. Mosley , Paul Decker
IPC分类号： G01N27/333 , G01N27/30
CPC分类号： G01N27/302 , G01N27/301 , G01N27/404 , G01N27/4167
摘要： Improvements in references electrodes, halogen sensors, pH sensors, TDS sensors, combinations thereof, and related methods.
摘要翻译：参考电极，卤素传感器，pH传感器，TDS传感器及其组合的改进以及相关方法。

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