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    • 74. 发明申请
    • PROCESS FOR PREPARING ISOSORBIDE DI(METH)ACRYLATE
    • 制备异氰酸酯二(甲基)丙烯酸酯的方法
    • US20160251371A1
    • 2016-09-01
    • US15054506
    • 2016-02-26
    • BASF SE
    • Andrea MISSKEFriederike FLEISCHHAKERChristoph FLECKENSTEINMartin KALLERRitesh NAIRUlrik STENGELMathieu BLANCHOT
    • C07D493/04C09K8/42C09K8/44C08F22/20
    • C07D493/04C08F22/20C09J4/00C09K8/426C09K8/44
    • A process for preparing isosorbide di(meth)acrylate by transesterifying alkyl (meth)acrylate with isosorbide, comprising the steps of: (i) reacting alkyl (meth)acrylate with isosorbide in the presence of a catalyst comprising titanium(IV) or zirconium(IV) and a stabilizer in the presence of an azeotroping agent which forms an azeotrope with the alcohol bound in the alkyl (meth)acrylate, (ii) continuously distilling off the azeotrope of azeotroping agent and alcohol, wherein steps (i) and (ii) are conducted simultaneously until the isosorbide has been essentially fully converted, (iii) adding water to the product mixture which comprises isosorbide (meth)acrylate and is obtained in steps (i) and (ii) and removing the hydrolyzate of the catalyst comprising titanium(IV) or zirconium(IV), (iv) distilling unconverted alkyl (meth)acrylate and azeotroping agent out of the product mixture, (v) distilling off water from the product mixture, wherein step (iv) can also be conducted before step (iii) and steps (iv) and (v) can also be conducted in one distillation step.
    • 包括以下步骤:(i)使(甲基)丙烯酸烷基酯与异山梨醇在含钛(Ⅳ)或锆(ⅰ)的催化剂的存在下反应来制备二(甲基)丙烯酸异山梨醇酯的方法, IV)和在与(甲基)丙烯酸烷基酯结合的醇形成共沸物的共沸剂存在下​​的稳定剂,(ii)连续蒸馏共沸剂和醇的共沸物,其中步骤(i)和(ii )同时进行,直到异山梨醇基本上完全转化,(iii)向包含异山梨醇(甲基)丙烯酸酯并在步骤(i)和(ii)中获得的产物混合物中加入水,并除去包含钛的催化剂的水解产物 (IV)或锆(IV),(iv)从产物混合物中蒸馏未转化的(甲基)丙烯酸烷基酯和共沸剂,(v)从产物混合物中蒸馏除去水,其中步骤(iv)也可以在步骤 (ii i)和步骤(iv)和(v)也可以在一个蒸馏步骤中进行。
    • 75. 发明申请
    • PROCESS FOR PREPARING ISOSORBIDE ETHOXYLATE DI(METH)ACRYLATE
    • 制备异氰酸酯二(甲基)丙烯酸酯的方法
    • US20160251370A1
    • 2016-09-01
    • US15051974
    • 2016-02-24
    • BASF SE
    • Andrea MISSKEFriederike FLEISCHHAKERChristoph FLECKENSTEINMartin KALLERUlrik STENGELMathieu BLANCHOTClaudia STOERRitesh NAIR
    • C07D493/04
    • C07D493/04C08F222/1006C09J4/00C09J4/06
    • A process for preparing isosorbide ethoxylate di(meth)acrylate by transesterifying alkyl (meth)acrylate with isosorbide ethoxylate, comprising the steps of: (i) ethoxylating isosorbide to give isosorbide ethoxylate, (ii) reacting alkyl (meth)acrylate with isosorbide ethoxylate in the presence of potassium phosphate as catalyst and a stabilizer and in the presence of an azeotroping agent which forms an azeotrope with the alcohol bound in the alkyl (meth)acrylate, (iii) continuously distilling off the azeotrope of azeotroping agent and alcohol, wherein steps (ii) and (iii) are conducted simultaneously until the isosorbide ethoxylate has been essentially fully converted, (iv) removing the catalyst from the product mixture comprising isosorbide ethoxylate di(meth)acrylate, (v) distilling unconverted alkyl (meth)acrylate and azeotroping agent out of the product mixture.
    • 包括以下步骤:(i)乙氧基化异山梨醇,得到异山梨醇乙氧基化物,(ii)使(甲基)丙烯酸烷基酯与异山梨醇乙氧基化物反应,得到异山梨醇乙氧基化物 在与(甲基)丙烯酸烷基酯结合的醇形成共沸物的共沸物存在下,连续蒸馏共沸剂和醇的共沸物,其中步骤 (ii)和(iii)同时进行,直到异山梨醇乙氧基化物已经基本上完全转化,(iv)从包含异山梨醇乙氧基化物二(甲基)丙烯酸酯的产物混合物中除去催化剂,(v)蒸馏未转化的(甲基) 共沸剂排出产品混合物。