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71. 发明申请

US20060089586A1 Convertible extracorporeal blood perfusion systems 审中-公开
标题翻译：可转换体外血液灌注系统
公开(公告)号：US20060089586A1
公开(公告)日：2006-04-27
申请号：US11254227
申请日：2005-10-19
申请人： Stanley Kaus , Thomas Rawles , Anthony Litzie
发明人： Stanley Kaus , Thomas Rawles , Anthony Litzie
IPC分类号： A61M37/00
CPC分类号： A61M1/3666 , A61M1/1698 , A61M1/3627 , A61M1/3667
摘要： A convertible extracorporeal blood perfusion system for receiving venous blood from a patient and for returning oxygenated blood to the patient in a cardiopulmonary bypass procedure including: a closed-loop cardiopulmonary bypass system; and a circuit for converting between the closed-loop cardiopulmonary bypass system and a cardiopulmonary bypass system containing a venous reservoir, the circuit for converting comprising a venous reservoir that can be fluidly connected to a venous line from the patient and that can be fluidly connected to the inlet of a first pump, the first pump being part of the closed-loop cardiopulmonary bypass system, the closed loop cardiopulmonary bypass system comprising a bubble removal device fluidly connected to the inlet of the first pump.
摘要翻译：一种可转换的体外血液灌注系统，用于接收来自患者的静脉血并将氧合血液返回到患者体外循环手术，包括：闭环心肺分流系统; 以及用于在闭环心肺分流系统和包含静脉储器的体外循环系统之间转换的电路，所述转换电路包括静脉储存器，其可以流体地连接到来自患者的静脉线路并且可以流体地连接到第一泵的入口，第一泵是闭环心肺分流系统的一部分，闭环心肺旁路系统包括流体连接到第一泵入口的气泡去除装置。

72. 发明授权

US06979423B2 Cardiopulmonary bypass device and method 有权
标题翻译：心肺分流装置及方法
公开(公告)号：US06979423B2
公开(公告)日：2005-12-27
申请号：US10374623
申请日：2003-02-24
申请人： Frederic H. Moll
发明人： Frederic H. Moll
IPC分类号： A61M1/36 , A61M1/14 , A61M37/00
CPC分类号： A61M1/3653 , A61M1/3659 , A61M1/3666 , Y10S128/03 , Y10S128/907
摘要： A method and system for performing a cardiopulmonary bypass procedure are provided. The method includes accessing a source of blood in a patient body from which source the blood is to be passed through a cardiopulmonary bypass machine, drawing blood from the source through the cardiopulmonary bypass machine and introducing the blood into an aortic artery of the patient body through a plurality of separate passages, after the blood has been passed through the cardiopulmonary bypass machine. The system includes a cardiopulmonary bypass machine, a tubular member coupled to an outlet port of the cardiopulmonary bypass machine and a plurality of separate needle members connected in fluid flow communication with the tubular member, the needle members being arranged to be connected in fluid flow communication with an aortic artery, during a cardiopulmonary bypass procedure.
摘要翻译：提供了一种用于执行心肺分流手术的方法和系统。该方法包括进入患者体内的血液来源，血源将通过体外循环机器从血液源通过心肺旁路机，从血液源抽取血液，并通过心肺旁路机将血液引入患者体内的主动脉，通过在血液已经通过心肺旁路机之后，多个单独的通道。所述系统包括心肺旁路机，连接到心肺旁路机的出口的管状部件和与管状部件流体连通地连接的多个单独的针部件，针部件布置成以流体流动连通与主动脉动脉，在体外循环手术期间。

73. 发明申请

US20050118059A1 Cardiopulmonary bypass extracorporeal blood circuit apparatus and method 审中-公开
标题翻译：体外循环体外血液回路装置及方法
公开(公告)号：US20050118059A1
公开(公告)日：2005-06-02
申请号：US10978830
申请日：2004-11-01
申请人： Robert Olsen , Walter Carpenter , John Dickey , Frederick Shorey , Laura Yonce
发明人： Robert Olsen , Walter Carpenter , John Dickey , Frederick Shorey , Laura Yonce
IPC分类号： A61M1/34 , A61M1/36 , A61M37/00
CPC分类号： A61M1/3627 , A61M1/3626 , A61M1/3643 , A61M1/3644 , A61M1/3652 , A61M1/3666 , A61M1/3667 , A61M2205/3379 , A61M2205/502 , A61M2205/505 , A61M2205/8206 , A61M2209/082
摘要： An extracorporeal blood circuit for use with a venous return line and an arterial line coupled to a patient. The extracorporeal blood circuit can include a venous air removal device coupled to the venous return line. The venous air removal device can perform an active air removal function. The extracorporeal blood circuit can include a sensor that determines a blood level in the venous air removal device, a purge line coupled to the venous air removal device, and a controller connected to the sensor. The controller can cause the venous air removal device to perform the active air removal function through the purge line when the blood level is less than a threshold. The extracorporeal blood circuit can further include a pump coupled to the venous air removal device, an oxygenator coupled to the pump, and a blood filter coupled to the oxygenator and the arterial line.
摘要翻译：用于静脉回流管和与患者相连的动脉线的体外血液回路。体外血液回路可以包括连接到静脉回流管的静脉除气装置。静脉除气装置可以进行有效的除气功能。体外血液回路可以包括确定静脉除气装置中的血液水平的传感器，连接到静脉除气装置的清除线以及连接到传感器的控制器。当血液水平低于阈值时，控制器可以使静脉除气装置通过清除管线执行主动除气功能。体外血液回路还可以包括耦合到静脉除气装置的泵，连接到泵的氧合器和耦合到氧合器和动脉管线的血液过滤器。

74. 发明申请

US20050004480A1 Mobile heart-lung machine 有权
标题翻译：移动心肺机
公开(公告)号：US20050004480A1
公开(公告)日：2005-01-06
申请号：US10839126
申请日：2004-05-06
申请人： Karsten Kirchhof
发明人： Karsten Kirchhof
IPC分类号： A61M1/16 , A61M1/36 , A61B5/02
CPC分类号： A61M1/3621 , A61M1/1698 , A61M1/3666 , A61M1/3667 , A61M2205/12 , A61M2205/8206
摘要： The present invention provides a heart-lung machine which can be carried by one person and can be used independently from an external power supply, consisting of at least three modules (1, 2, 3), wherein a first module (1) contains the blood circulating elements which are necessary for the function of a heart-lung machine, a second module (2) contains a pump drive (9) and an electronic measuring equipment and a control logic (11) and a third module (3) contains the programming unit (14), whereas the second unit is separably connected to the first and the third module.
摘要翻译：本发明提供一种可以由一个人携带并且可以独立于由至少三个模块（1,2,3）组成的外部电源使用的心肺机器，其中第一模块（1）包含血液循环元件对于心肺机器的功能是必需的，第二模块（2）包含泵驱动器（9）和电子测量设备以及控制逻辑（11）和第三模块（3）编程单元（14），而第二单元可分离地连接到第一和第三模块。

75. 发明申请

US20040219060A1 Device and methods for processing blood in extracorporeal circulation 审中-公开
标题翻译：用于处理体外循环血液的装置和方法
公开(公告)号：US20040219060A1
公开(公告)日：2004-11-04
申请号：US10804583
申请日：2004-03-18
发明人： Edgardo Costa Maianti , Nicola Ghelli , Ivo Panzani
IPC分类号： A61M001/14 , A61M037/00 , A61M001/34 , A61M001/36
CPC分类号： A61M1/3627 , A61M1/1006 , A61M1/101 , A61M1/1698 , A61M1/3606 , A61M1/3666 , A61M1/3667
摘要： A device for processing blood in extracorporeal blood circuit, which comprises, integrated in a single monolithic assembly, a bubble trap, a centrifugal pump, a heat exchanger, an oxygenator and an arterial filter.
摘要翻译：用于处理体外血液回路中的血液的装置，其包括集成在单个整体组件中的气泡阱，离心泵，热交换器，氧合器和动脉过滤器。

76. 发明申请

US20040217054A1 Extracorporeal blood circuit air removal system and method 有权
标题翻译：体外血液回路除气系统及方法
公开(公告)号：US20040217054A1
公开(公告)日：2004-11-04
申请号：US10743598
申请日：2003-12-22
发明人： Robert W. Olsen , Walter L. Carpenter , John B. Dickey , Frederick A. Shorey , Laura A. Yonce , Mark D. Stringham
IPC分类号： B01D061/00
CPC分类号： A61M1/3627 , A61M1/1006 , A61M1/101 , A61M1/1012 , A61M1/1086 , A61M1/1089 , A61M1/32 , A61M1/3626 , A61M1/3664 , A61M1/3666 , A61M1/3667 , A61M1/367 , A61M2205/3379 , A61M2205/50 , A61M2205/502 , A61M2205/505 , A61M2205/8206 , A61M2209/08 , A61M2209/082 , Y10S261/28
摘要： A disposable, integrated extracorporeal blood circuit employed during cardiopulmonary bypass surgery performs gas exchange, heat transfer, and microemboli filtering functions in a way as to conserve volume, to reduce setup and change out times, to eliminate a blood reservoir, and to substantially reduce blood-air interface. Blood from the patient or prime solution is routed through an air removal device that is equipped with air sensors for detection of air. An active air removal controller removes detected air from blood in the air removal device. A disposable circuit support module is used to mount the components of the disposable, integrated extracorporeal blood circuit in close proximity and in a desirable spatial relationship to optimize priming and use of the disposable, integrated extracorporeal blood circuit. A reusable circuit holder supports the disposable circuit support module in relation to a prime solution source, the active air removal controller and other components.
摘要翻译：在体外循环手术中使用的一次性，综合的体外血液回路以节省体积，减少建立和改变时间，消除血液储存器和大大减少血液的方式进行气体交换，热传递和微栓塞过滤功能 - 界面。来自患者或主溶液的血液通过装备有用于检测空气的空气传感器的空气去除装置。主动除气控制器从空气去除装置中的血液中除去检测到的空气。一次性电路支持模块用于将一次性的，集成的体外血液回路的部件安装在非常接近的位置并且具有期望的空间关系，以优化一次性的，集成的体外血液回路的灌注和使用。一个可重复使用的电路支架支持一次性电路支撑模块相对于主要解决方案源，主动空气去除控制器和其他组件。

77. 发明授权

US06811749B2 Self-contained pack assembly for an extracorporeal blood circuit 失效
标题翻译：用于体外血液回路的独立包装组件
公开(公告)号：US06811749B2
公开(公告)日：2004-11-02
申请号：US09964416
申请日：2001-09-28
申请人： Erin J. Lindsay
发明人： Erin J. Lindsay
IPC分类号： A61M114
CPC分类号： A61M1/3621 , A61M1/1698 , A61M1/3666 , A61M2209/082 , Y10S261/28
摘要： A self-contained pack assembly includes all of the disposable components of an extracorporeal support circuit for cardiac bypass surgery. The pack assembly comprises a blood reservoir, a blood oxygenator, and a carrier for vertically mounting the blood reservoir and blood oxygenator. Trays may be releasably attached to the carrier to serve as containers for coiled tubing used in the support circuit.
摘要翻译：独立包装组件包括用于心脏旁路手术的体外支持电路的所有一次性部件。包装组件包括血液储存器，血液充氧器和用于垂直安装血液储存器和血液充氧器的载体。托盘可以可释放地附接到载体上，以用作用于支撑回路中的连续油管的容器。

78. 发明授权

US06773670B2 Blood filter having a sensor for active gas removal and methods of use 失效
标题翻译：血液过滤器具有用于活性气体去除的传感器和使用方法
公开(公告)号：US06773670B2
公开(公告)日：2004-08-10
申请号：US10067434
申请日：2002-02-05
申请人： Steven K. Stringer , Kevin L. Hultquist , Mehrdad Farhangnia , Fred I. Linker , Ben F. Brian, III
发明人： Steven K. Stringer , Kevin L. Hultquist , Mehrdad Farhangnia , Fred I. Linker , Ben F. Brian, III
IPC分类号： A61M136
CPC分类号： A61M1/3626 , A61M1/1006 , A61M1/101 , A61M1/262 , A61M1/267 , A61M1/3606 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3666 , Y10S128/03 , Y10S261/28 , Y10S417/902
摘要： Apparatus and methods for removing gas from a blood handling system. A filter apparatus for monitoring and removing gas is provided comprising of a gas removal/blood filter, a sensor to sense the presence of gas, and a valve operably coupled to the sensor to evacuate gas from the apparatus when the sensor detects an accumulation of gas. When used with a previously known blood handling system, the present filter apparatus facilitates priming and the addition of additional blood handling elements during operation of the blood handling system.
摘要翻译：从血液处理系统中除去气体的装置和方法。提供了一种用于监测和去除气体的过滤装置，其包括气体去除/血液过滤器，用于感测气体存在的传感器，以及可操作地耦合到传感器的阀，当传感器检测到气体的积聚时，从装置排出气体。当与先前已知的血液处理系统一起使用时，本过滤装置有利于在血液处理系统的操作期间起动和添加额外的血液处理元件。

79. 发明授权

US06689315B2 Integrated blood handling system having improved pump 失效
标题翻译：具有改进泵的综合血液处理系统
公开(公告)号：US06689315B2
公开(公告)日：2004-02-10
申请号：US10117964
申请日：2002-04-05
申请人： Fred I. Linker , Jean-Pierre Dueri , Paul LaRoy Edwards , Ronald Cambron , Ben F. Brian, III
发明人： Fred I. Linker , Jean-Pierre Dueri , Paul LaRoy Edwards , Ronald Cambron , Ben F. Brian, III
IPC分类号： A61M136
CPC分类号： A61M1/3626 , A61M1/1006 , A61M1/101 , A61M1/262 , A61M1/267 , A61M1/3606 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3666 , Y10S128/03 , Y10S261/28 , Y10S417/902
摘要： Apparatus and methods for pumping and oxygenating blood are provided that include a gas removal system and a pump impeller with a single piece metal insert. An integrated blood processing unit is provided in which a gas removal/blood filter, pump and blood oxygenation element are mounted within a common housing. The gas removal system includes a sensor mounted on the housing to sense the presence of gas, and a valve is operably coupled to the sensor to evacuate gas from the system when the sensor detects an accumulation of gas.
摘要翻译：提供了用于泵送和充氧血液的装置和方法，其包括气体去除系统和具有单件金属插入件的泵叶轮。提供了一种集成血液处理单元，其中气体去除/血液过滤器，泵和血氧元件安装在公共壳体内。气体去除系统包括安装在壳体上以感测气体存在的传感器，并且当传感器检测到气体积聚时，阀可操作地耦合到传感器以从系统排出气体。

80. 发明申请

US20030176830A1 Aortic balloon occlusion cannula 失效
标题翻译：主动脉夹闭气囊
公开(公告)号：US20030176830A1
公开(公告)日：2003-09-18
申请号：US10099496
申请日：2002-03-13
发明人： Albertus Scheule
IPC分类号： A61M037/00 , A61M029/00
CPC分类号： A61M25/1011 , A61M1/3653 , A61M1/3659 , A61M1/3666 , A61M25/0032 , A61M25/0041 , A61M25/0068 , A61M25/104 , A61M2025/0031 , A61M2025/004 , A61M2025/1015 , A61M2025/1052 , A61M2025/1095
摘要： An aortic balloon occlusion cannula for the occlusion of the aorta ascendens during cardiac surgery including a cannula containing several lumina that are separated from one another. The cannula carries two dilatable occlusion balloons positioned at a distance from each other, one of the balloons being neighbored to the distal end of the cannula which faces away from the heart and each of the balloons being connected to its own lumen which enables its dilation in independence from the other balloon. The cannula is insertable through the lefthand ventricle of the heart and through the valvula aortae and includes at least one further lumen. The further lumen being connected on the distal side, facing the body, of the distal occlusion balloon to the lumen of the aorta and is adapted to be connected to an extracorporal blood supply device. An additional separate lumen is provided in the cannula and forms a return conduit for liquid and opens on the proximal side of the proximal occlusion balloon.
摘要翻译：用于在心脏手术期间闭塞主动脉上行的主动脉球囊闭塞插管，包括包含彼此分离的几个腔的套管。套管携带两个彼此间隔一定距离的可扩张的闭塞气囊，其中一个气球与套管的远端相邻，套管的远端远离心脏，每个球囊连接到自己的内腔，使其能够扩张独立于另一个气球。套管可以通过心脏左心室和瓣膜主动脉插入，并且包括至少一个另外的腔。远侧阻塞气囊的远端侧的远侧连接到主动脉的内腔，并适于连接到体外供血装置。在套管中提供另外的分开的内腔，并形成用于液体的返回导管并且在近端阻塞气囊的近侧开口。

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