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    • 71. 发明授权
    • Tumor suppressor gene
    • 肿瘤抑制基因
    • US5559023A
    • 1996-09-24
    • US384850
    • 1995-02-07
    • Yusuke NakamuraTakashi Imai
    • Yusuke NakamuraTakashi Imai
    • A61K38/00C07K14/47C07K14/82C12N5/10C07H21/04
    • C07K14/82C07K14/4703A61K38/00
    • A detailed genetic map on human chromosome 11 was prepared. Then, a commonly deleted region on the chromosome in the tumor tissues of patients with multiple endocrine neoplasia type 1 was identified. Further, by linkage analysis of a family line with this disease, a genetic cause for this disease was localized. A gene present in the region common to these observations was cloned and the structure of this gene was determined. Because a protein coded by this DNA is homologous with those of transcriptional factors, it is expected that the above-mentioned gene may be a novel tumor suppressor gene. Further, it is also expected that the above-mentioned gene and a protein coded for thereby may be useful in preparation of a remedy for cancer and a diagnostic drug for cancer.
    • 准备了人类染色体11上的详细遗传图谱。 然后,鉴定了多发性内分泌瘤1型患者肿瘤组织染色体上普遍缺失的一个区域。 此外,通过家族系与这种疾病的联系分析,本病的遗传原因是本病。 克隆了与这些观察结果共同的区域中存在的基因,并测定了该基因的结构。 由于由该DNA编码的蛋白质与转录因子的蛋白质同源,所以预期上述基因可能是新的肿瘤抑制基因。 此外,还预期上述基因和由此编码的蛋白质可用于制备癌症治疗剂和癌症诊断药物。
    • 80. 发明申请
    • RAPID CHARGER
    • 快速充电
    • US20130020983A1
    • 2013-01-24
    • US13520348
    • 2011-01-07
    • Hirofumi IshikawaAtsushi TamuraTakahiro ShimamuraMasato ImaizumiTakashi Imai
    • Hirofumi IshikawaAtsushi TamuraTakahiro ShimamuraMasato ImaizumiTakashi Imai
    • H02J7/02
    • H02J7/0054B60L53/11B60L53/14H02J5/00H02J7/02Y02T10/7005Y02T10/7072Y02T90/121Y02T90/128Y02T90/14
    • A rapid charger includes a storage battery for equipment, a DC power supply unit which converts AC power of an AC power supply into DC power, and a controller which controls the DC power supply unit such that the DC power supply unit generates DC power to charge the storage battery for equipment from the AC power of the AC power supply and allows the DC power to be supplied from the DC power supply unit to the storage battery for equipment during charging of the storage battery for equipment, wherein, when a storage battery for driving power as a load is connected, the controller allows the DC power supply unit and the storage battery for equipment to form a series circuit, controls the DC power supply unit such that the DC power supply unit generates a predetermined DC power from the AC power of the AC power supply, adds the predetermined DC power to the DC power of the storage battery for equipment to generate DC power to charge the storage battery for driving power, and allows the DC power to be supplied to the storage battery for driving power.
    • 快速充电器包括用于设备的蓄电池,将AC电源的AC电力转换为DC电力的DC电源单元,以及控制DC电源单元的控制器,使得DC电源单元产生DC电力 所述交流电源的交流电源的设备用蓄电池,在所述设备用蓄电池充电期间,使所述直流电源从所述直流电源单元向所述设备用蓄电池供电,其特征在于, 驱动电源作为负载连接,控制器允许直流电源单元和设备的蓄电池形成串联电路,控制直流电源单元,使得直流电源单元从交流电源产生预定的直流电力 将预定的直流电力与用于设备的蓄电池的直流电力相加,以产生用于对用于驱动电力的蓄电池进行充电的DC电力,并且允许D C电源供给到用于驱动电力的蓄电池。