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71. 发明申请

US20050178958A1 Mass spectrometer 审中-公开
标题翻译：质谱仪
公开(公告)号：US20050178958A1
公开(公告)日：2005-08-18
申请号：US11071370
申请日：2005-03-04
申请人： Robert Bateman , Kevin Giles , Steve Pringle
发明人： Robert Bateman , Kevin Giles , Steve Pringle
IPC分类号： H01J49/42 , H01J49/00
CPC分类号： H01J49/062
摘要： An ion tunnel ion trap comprises a plurality of electrodes having apertures. The ion tunnel ion trap is preferably coupled to a time of flight mass analyser.
摘要翻译：离子隧道离子阱包括具有孔的多个电极。离子隧道离子阱优选与飞行时间质量分析器相连。

72. 发明授权

US06914241B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US06914241B2
公开(公告)日：2005-07-05
申请号：US10868934
申请日：2004-06-17
申请人： Kevin Giles , John Brian Hoyes , Steve Pringle , Jason Lee Wildgoose
发明人： Kevin Giles , John Brian Hoyes , Steve Pringle , Jason Lee Wildgoose
IPC分类号： H01J49/00 , H01J49/40
CPC分类号： G01N27/622
摘要： A mass spectrometer comprising an ion mobility separator for separating ions according to their ion mobility is disclosed. The ion mobility separator comprises a plurality of electrodes and one or more transient DC voltages or one or more transient DC voltage waveforms are progressively applied to the electrodes so that ions having a certain ion mobility are separated from other ions having different ion mobilities.
摘要翻译：公开了一种包括用于根据离子迁移率分离离子的离子迁移率分离器的质谱仪。离子迁移率分离器包括多个电极和一个或多个瞬态DC电压或一个或多个瞬态DC电压波形逐渐施加到电极，使得具有一定离子迁移率的离子与具有不同离子迁移率的其它离子分离。

73. 发明申请

US20050050451A1 Automated inspection of packaging materials for package integrity 有权
标题翻译：自动检查包装材料的包装完整性
公开(公告)号：US20050050451A1
公开(公告)日：2005-03-03
申请号：US10734358
申请日：2003-12-12
申请人： Mohsen Abdollahi , Kevin Giles , Charles Guffey , Jun Liu , Bernard Roche , Peter Sites , Robert Whalen
发明人： Mohsen Abdollahi , Kevin Giles , Charles Guffey , Jun Liu , Bernard Roche , Peter Sites , Robert Whalen
IPC分类号： G01N21/95 , G06F17/00
CPC分类号： G01N21/95
摘要： An apparatus in one example comprises a computer component that receives one or more images of one or more packaging materials from one or more imaging components. The computer component employs an analysis of the one or more images to make a determination of a package integrity of the one or more packaging materials.
摘要翻译：一个示例中的装置包括从一个或多个成像部件接收一个或多个包装材料的一个或多个图像的计算机部件。计算机组件采用对一个或多个图像的分析来确定一个或多个包装材料的包装完整性。

74. 发明申请

US20050023453A1 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US20050023453A1
公开(公告)日：2005-02-03
申请号：US10633702
申请日：2003-08-05
申请人： Robert Bateman , Kevin Giles , John Hoyes , Steve Pringle , Jeff Brown
发明人： Robert Bateman , Kevin Giles , John Hoyes , Steve Pringle , Jeff Brown
IPC分类号： H01J49/00 , H01J49/42
CPC分类号： H01J49/4225
摘要： A mass spectrometer is disclosed comprising an ion trap wherein ions which have been temporally separated according to their mass to charge ratio or ion mobility enter the ion trap. Once at least some of the ions have entered the ion trap, a plurality of ion trapping regions are created along the length of the ion trap in order to fractionate the ions. Alternatively, the ions may be received within one or more axial trapping regions which are translated along the ion trap with a velocity which is progressively reduced to zero.
摘要翻译：公开了一种质谱仪，其包括离子阱，其中根据其质荷比或离子迁移率暂时分离的离子进入离子阱。一旦至少一些离子已经进入离子阱，沿着离子阱的长度产生多个离子捕获区域，以分离离子。或者，离子可以被接收在一个或多个沿着离子阱平移的轴向捕获区域中，其速度逐渐减小到零。

75. 发明授权

US06794641B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US06794641B2
公开(公告)日：2004-09-21
申请号：US10448059
申请日：2003-05-30
申请人： Robert Harold Bateman , Kevin Giles , Steve Pringle
发明人： Robert Harold Bateman , Kevin Giles , Steve Pringle
IPC分类号： H01J4940
CPC分类号： H01J49/062 , H01J49/004
摘要： A mass spectrometer is disclosed wherein ions from a pulsed ion source are dispersed in a drift region so that the ions become separated according to their mass to charge ratios. The ions are then received by an ion guide in which multiple trapping regions are created and wherein the multiple trapping regions are translated along the length of the ion guide. The ion guide receives the ions so that all the ions trapped in a particular trapping region have substantially the same or similar mass to charge ratios. The ions are released from the exit of the ion guide and the pusher/puller electrode of an orthogonal acceleration Time of Flight mass analyzer is arranged to be energised in synchronization with the ions emerging from the ion guide. The trapping regions may be translated along the ion guide with a velocity which becomes progressively slower and the delay time of the pusher/puller electrode may be progressively increased.
摘要翻译：公开了一种质谱仪，其中来自脉冲离子源的离子分散在漂移区域中，使得离子根据其质荷比分离。然后由离子导向器接收离子，其中产生多个俘获区域，并且其中多个俘获区域沿离子导向件的长度平移。离子导向器接收离子，使得捕获在特定捕获区域中的所有离子具有基本上相同或相似的质荷比。离子从离子导向器的出口释放，并且正交加速时间飞行质量分析器的推动器/牵引电极被布置成与从离子导向器出射的离子同步地通电。俘获区域可以沿着离子导向器平移，速度逐渐变慢，并且推动器/拉电极的延迟时间可以逐渐增加。

76. 发明授权

US09620346B2 Mass spectrometer 有权
公开(公告)号：US09620346B2
公开(公告)日：2017-04-11
申请号：US11721729
申请日：2005-12-16
申请人： Kevin Giles
发明人： Kevin Giles
IPC分类号： H01J49/26 , H01J49/06
CPC分类号： H01J49/062 , Y10T29/49165
摘要： A mass spectrometer is disclosed comprising an ion guide. The ion guide comprises a hollow tubular conductor having a wall. One or more electrodes are provided in the wall of the tubular conductor. An exit aperture is provided in the wall of the tubular conductor downstream of the one or more electrodes. An AC or RF voltage is applied to the one or more electrodes and a DC potential difference is maintained between the wall of the tubular conductor and the one or more electrodes. The combination of a DC voltage gradient and applying an AC or RF voltage to the electrodes is that ions are confined radially to a region which is preferably close to the one or more electrodes. Ions are preferably extracted from the ion guide via the exit aperture.

77. 发明授权

US09460906B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US09460906B2
公开(公告)日：2016-10-04
申请号：US11813221
申请日：2006-01-17
申请人： Kevin Giles , Martin Green , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Green , Jason Lee Wildgoose
IPC分类号： H01J49/26 , H01J49/42
CPC分类号： H01J49/4235 , H01J49/4275
摘要： An ion guide or ion trap is disclosed comprising a segmented linear ion guide or ion trap. Ions are confined radially within the ion guide or ion trap by the application of an AC or RF voltage to the electrodes. A static potential well is maintained along at least a portion of the axial length of the ion guide or ion trap. A time varying homogeneous electric field is applied along at least a portion of the axial length of the ion guide or ion trap. The combination of the static axial potential well and the time varying axial homogeneous electric field causes ions to be ejected from the ion guide or ion trap in a substantially non-resonant manner.
摘要翻译：公开了一种离子导向器或离子阱，其包括分段线性离子导向器或离子阱。通过向电极施加AC或RF电压，离子限制在离子导向器或离子阱内径向。沿着离子导向器或离子阱的轴向长度的至少一部分保持静电势阱。沿着离子导向器或离子阱的轴向长度的至少一部分施加时变均匀电场。静态轴向势阱和随时间变化的轴向均匀电场的组合导致离子以基本上非共振的方式从离子导向器或离子阱排出。

78. 发明授权

US08952320B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US08952320B2
公开(公告)日：2015-02-10
申请号：US11719665
申请日：2005-11-18
申请人： Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
发明人： Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
IPC分类号： H01J49/26 , H01J49/42
CPC分类号： H01J49/4215 , H01J49/428
摘要： A mass spectrometer is disclosed comprising a quadrupole rod set ion guide or mass filter device (6). A broadband frequency signal (10) having one or more notches (11a, 11b, 11c) is applied to the rods of the quadrupole rod set (6). The notched broadband frequency signal (10) causes undesired ions to be resonantly ejected from the ion guide (6). The notched broadband frequency signal (10) has frequency components missing which correspond with the resonance frequency of ions which are desired to be onwardly transmitted. The ion guide or mass filter device (6) enables a plurality of desired ions having different mass to charge ratios to be simultaneously transmitted by the ion guide or mass filter device (6) whilst other ions are resonantly ejected from the ion guide or mass filter device (6).
摘要翻译：公开了一种质谱仪，其包括四极杆离子导向器或质量过滤装置（6）。具有一个或多个凹口（11a，11b，11c）的宽频率信号（10）被施加到四极杆组（6）的杆上。有缺口的宽带频率信号（10）使不想要的离子从离子导向器（6）共振地弹出。缺口宽带频率信号（10）具有与期望向前发射的离子的谐振频率相对应的频率分量。离子导向器或质量过滤装置（6）使得具有不同质荷比的多个所需离子能够由离子导向器或质量过滤装置（6）同时传输，而其它离子从离子导向器或质量过滤器装置（6）。

79. 发明授权

US08440967B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US08440967B2
公开(公告)日：2013-05-14
申请号：US12917755
申请日：2010-11-02
申请人： Kevin Giles
发明人： Kevin Giles
IPC分类号： H01J49/00
CPC分类号： H01J49/065 , G01N27/624
摘要： A device for separating ions according to differences in their ion mobility as a function of electric field strength is disclosed. The device comprises an upper electrode, a lower electrode and a plurality of intermediate electrodes. An asymmetric voltage waveform is applied to the upper electrode and a DC compensating voltage is applied to the lower electrode.
摘要翻译：公开了根据其离子迁移率的差异作为电场强度的函数分离离子的装置。该装置包括上电极，下电极和多个中间电极。向上部电极施加非对称电压波形，向下部电极施加直流补偿电压。

80. 发明授权

US08153960B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US08153960B2
公开(公告)日：2012-04-10
申请号：US11916438
申请日：2006-06-05
申请人： Kevin Giles , Martin Green , Steven Derek Pringle , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Green , Steven Derek Pringle , Jason Lee Wildgoose
IPC分类号： H01J49/26
CPC分类号： H01J49/427 , H01J49/4235
摘要： An ion guide or ion trap (1) is disclosed having an entrance electrode (2) and an exit electrode (3). The potential of the exit electrode (3) is periodically dropped for a relatively short period of time allowing some ions to escape from the ion guide or ion trap (1) via an aperture in the exit electrode (3). The period of time that the potential of the exit electrode (3) is dropped for is progressively increased and ions emerge from the ion guide or ion trap (1) in a mass to charge ratio dependent manner. The ion guide or ion trap (1) may be operated as a mass separator or low resolution mass analyser.
摘要翻译：公开了一种具有入口电极（2）和出口电极（3）的离子导向器或离子阱（1）。出口电极（3）的电位周期性地下降相当短的时间段，允许一些离子通过出射电极（3）中的孔从离子导向器或离子阱（1）逸出。退出电极（3）的电位下降的时间段逐渐增加，并且离子导向器或离子阱（1）以质荷比依赖的方式出现离子。离子导向器或离子阱（1）可以作为质量分离器或低分辨率质量分析器来操作。

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