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71. 发明授权

US07189204B2 Sleep detection using an adjustable threshold 有权
标题翻译：使用可调阈值进行睡眠检测
公开(公告)号：US07189204B2
公开(公告)日：2007-03-13
申请号：US10309771
申请日：2002-12-04
申请人： Quan Ni , Zoe Hajenga , Douglas R. Daum , Jeff E. Stahmann , John D. Hatlestad , Kent Lee
发明人： Quan Ni , Zoe Hajenga , Douglas R. Daum , Jeff E. Stahmann , John D. Hatlestad , Kent Lee
IPC分类号： A61B5/02 , A61B5/00 , A61B5/08
CPC分类号： A61B5/4815 , A61B5/0031 , A61B5/0205 , A61B5/021 , A61B5/085 , A61B5/1116 , A61B5/4809 , A61B5/686 , A61B5/7271 , A61B5/7282 , A61N1/362 , A61N1/365 , A61N1/36542 , G16H40/63 , G16H50/20
摘要： Devices and methods for sleep detection involve the use of an adjustable threshold for detecting sleep onset and termination. A method for detecting sleep includes adjusting a sleep threshold associated with a first sleep-related signal using a second sleep-related signal. The first sleep-related signal is compared to the adjusted threshold and sleep is detected based on the comparison. The sleep-related signals may be derived from implantable or external sensors. Additional sleep-related signals may be used to confirm the sleep condition. A sleep detector device implementing a sleep detection method may be a component of an implantable pulse generator such as a pacemaker or defibrillator.
摘要翻译：用于睡眠检测的装置和方法涉及使用可调阈值来检测睡眠开始和终止。一种用于检测睡眠的方法包括使用第二睡眠相关信号来调整与第一睡眠相关信号相关联的睡眠阈值。将第一睡眠相关信号与调整后的阈值进行比较，并根据比较检测睡眠。睡眠相关信号可以从可植入或外部传感器得到。可以使用额外的睡眠相关信号来确认睡眠状况。实现睡眠检测方法的睡眠检测器装置可以是诸如起搏器或除颤器的可植入脉冲发生器的部件。

72. 发明申请

US20060241512A1 Thoracic or intracardiac impedance detection with automatic vector selection 有权
公开(公告)号：US20060241512A1
公开(公告)日：2006-10-26
申请号：US11110418
申请日：2005-04-20
申请人： Jonathan Kwok , Kent Lee , Jesse Hartley , Jeffrey Stahmann , Yinghong Yu , Jiang Ding
发明人： Jonathan Kwok , Kent Lee , Jesse Hartley , Jeffrey Stahmann , Yinghong Yu , Jiang Ding
IPC分类号： A61B5/05
CPC分类号： A61B5/0205 , A61B5/053 , A61B5/0538 , A61N1/36185 , A61N1/36521 , A61N1/3686
摘要： This document discusses, among other things, a cardiac function management device or other implantable medical device that includes a test mode and a diagnostic mode. During a test mode, the device cycles through various electrode configurations for collecting thoracic impedance data. At least one figure of merit is calculated from the impedance data for each such electrode configuration. In one example, only non-arrhythmic beats are used for computing the figure of merit. A particular electrode configuration is automatically selected using the figure of merit. During a diagnostic mode, the device collects impedance data using the selected electrode configuration. In one example, the figure of merit includes a ratio of a cardiac stroke amplitude and a respiration amplitude. Other examples of the figure of merit are also described.

73. 发明申请

US20050145246A1 Posture detection system and method 有权
标题翻译：姿态检测系统及方法
公开(公告)号：US20050145246A1
公开(公告)日：2005-07-07
申请号：US10943079
申请日：2004-09-15
申请人： Jesse Hartley , Jeffrey Stahmann , Kent Lee , Quan Ni
发明人： Jesse Hartley , Jeffrey Stahmann , Kent Lee , Quan Ni
IPC分类号： A61B5/00 , A61B5/0205 , A61B5/0215 , A61B5/042 , A61B5/0464 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/053 , A61B5/08 , A61B5/083 , A61B5/085 , A61B5/087 , A61B5/103 , A61B5/113 , A61M15/00 , A61M16/00 , A61M16/10 , A61N1/18 , A61N1/20 , A61N1/362 , A61N1/365 , A61N1/37
CPC分类号： A61N1/36514 , A61B5/0031 , A61B5/02055 , A61B5/0215 , A61B5/02405 , A61B5/0421 , A61B5/0422 , A61B5/0464 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/053 , A61B5/0809 , A61B5/0836 , A61B5/087 , A61B5/103 , A61B5/1116 , A61B5/113 , A61B5/4818 , A61B5/6814 , A61B5/6823 , A61B5/686 , A61B2560/0462 , A61B2562/0219 , A61M16/024 , A61M16/10 , A61M2016/0021 , A61M2016/0039 , A61M2016/0042 , A61M2205/3561 , A61M2205/3592 , A61M2230/04 , A61M2230/10 , A61M2230/432 , A61M2230/435 , A61M2230/60 , A61M2230/63 , A61M2230/65 , A61N1/3601 , A61N1/36535
摘要： A posture detection system includes an implantable device and a patient-external respiratory therapy device coupled via a communications channel. At least one of the implantable device and the patient-external respiratory therapy devices includes a posture detector. Posture information is transferred between the implantable device and the patient-external respiratory therapy device. The posture information may be used in connection with sleep detection or to modify therapy delivered by the implantable cardiac device and/or the patient-external respiratory therapy device.
摘要翻译：姿态检测系统包括通过通信信道耦合的可植入装置和患者外部呼吸治疗装置。可植入装置和患者外部呼吸治疗装置中的至少一个包括姿势检测器。姿态信息在可植入装置和患者外部呼吸治疗装置之间传递。姿势信息可以与睡眠检测结合使用或者修改由可植入心脏装置和/或患者外部呼吸治疗装置递送的治疗。

74. 发明申请

US20050080463A1 System and method for detecting an involuntary muscle movement disorder 有权
标题翻译：用于检测不自主肌肉运动障碍的系统和方法
公开(公告)号：US20050080463A1
公开(公告)日：2005-04-14
申请号：US10939639
申请日：2004-09-13
申请人： Jeffrey Stahmann , Jesse Hartley , Kent Lee , Quan Ni
发明人： Jeffrey Stahmann , Jesse Hartley , Kent Lee , Quan Ni
IPC分类号： A61B5/04 , A61B5/0488 , A61B5/103 , A61B5/11 , A61M31/00 , A61N1/36
CPC分类号： A61B5/0488 , A61B5/1107 , A61B5/4806 , A61B5/4809 , A61B5/4812 , A61B5/6869 , A61B2505/05 , A61N1/36003
摘要： Methods and systems are directed to evaluating a pathological condition and involve acquiring muscle movement signals, such as electromyogram (EMG) or accelerometer signals, and detecting the presence of the pathological condition. Methods and systems also provide for detecting sleep-related involuntary muscle disorders and non sleep-related involuntary muscle disorders using muscle movement signals. Drug therapy, transcutaneous electric nerve stimulation therapy, or other therapy may be delivered to treat a detected or diagnosed involuntary muscle disorder.
摘要翻译：方法和系统旨在评估病理状况，并涉及获取肌肉运动信号，如肌电图（EMG）或加速度计信号，并检测病理状况的存在。方法和系统还提供使用肌肉运动信号来检测与睡眠相关的非自主性肌肉疾病和非睡眠相关的非自主性肌肉障碍。药物治疗，经皮电神经刺激治疗或其他治疗可以被递送以治疗检测到或诊断的非自愿肌肉疾病。

75. 发明申请

US20050076905A1 Use of external respiratory therapy device to detect cardiac electrical activity 有权
标题翻译：使用外部呼吸治疗装置检测心脏电活动
公开(公告)号：US20050076905A1
公开(公告)日：2005-04-14
申请号：US10922351
申请日：2004-08-19
申请人： Jeffrey Stahmann , Jesse Hartley , Kent Lee , Quan Ni
发明人： Jeffrey Stahmann , Jesse Hartley , Kent Lee , Quan Ni
IPC分类号： A61B5/00 , A61B5/0205 , A61B5/0215 , A61B5/042 , A61B5/0464 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/053 , A61B5/08 , A61B5/083 , A61B5/085 , A61B5/087 , A61B5/103 , A61B5/113 , A61M15/00 , A61M16/00 , A61M16/10 , A61N1/18 , A61N1/20 , A61N1/362 , A61N1/365 , A61N1/37
CPC分类号： A61B5/02405 , A61B5/0031 , A61B5/02055 , A61B5/0215 , A61B5/0421 , A61B5/0422 , A61B5/0464 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/053 , A61B5/0809 , A61B5/0836 , A61B5/087 , A61B5/103 , A61B5/1116 , A61B5/113 , A61B5/4818 , A61B5/6803 , A61B5/6823 , A61B5/686 , A61B2562/0219 , A61M16/0051 , A61M16/024 , A61M16/10 , A61M2016/0021 , A61M2016/0039 , A61M2016/0042 , A61M2205/3561 , A61M2205/3592 , A61M2230/04 , A61M2230/10 , A61M2230/432 , A61M2230/435 , A61M2230/60 , A61M2230/63 , A61M2230/65 , A61N1/362 , A61N1/3627 , A61N1/36514 , A61N1/36592 , A61N1/37
摘要： Methods and systems provide an integrated approach to respiratory and cardiac monitoring, diagnosis and/or therapy. A medical system includes one or more cardiac electrodes coupled to an external respiratory therapy device. The cardiac electrodes sense cardiac electrical activity that is used to generate an electrocardiogram (ECG) signal. Cardiac events, such as arrhythmia, myocardial infarction and/or ischemia, may be detected based on the sensed cardiac electrical activity.
摘要翻译：方法和系统提供了呼吸和心脏监测，诊断和/或治疗的综合方法。医疗系统包括联接到外部呼吸治疗装置的一个或多个心脏电极。心脏电极感测用于产生心电图（ECG）信号的心脏电活动。可以基于感测到的心脏电活动来检测心脏事件，例如心律失常，心肌梗塞和/或局部缺血。

76. 发明申请

US20050061320A1 Coordinated use of respiratory and cardiac therapies for sleep disordered breathing 失效
标题翻译：协调使用呼吸和心脏治疗睡眠呼吸障碍
公开(公告)号：US20050061320A1
公开(公告)日：2005-03-24
申请号：US10930979
申请日：2004-08-31
申请人： Kent Lee , Jesse Hartley , Jeffrey Stahmann , Quan Ni
发明人： Kent Lee , Jesse Hartley , Jeffrey Stahmann , Quan Ni
IPC分类号： A61M16/00 , A61N1/36 , A61N1/365 , A62B7/00
CPC分类号： A61M16/00 , A61M16/0009 , A61M16/026 , A61M2205/3523 , A61M2230/00 , A61M2230/60 , A61N1/3601 , A61N1/36514 , G06F19/00
摘要： Methods and systems involve coordinating therapies used for treating disordered breathing. Disordered breathing therapies may include cardiac electrical stimulation therapy and external respiratory therapy as well as other therapies for treating disordered breathing in a patient. The therapies delivered to the patient may be coordinated to enhance effectiveness of the therapy, to reduce therapy interactions, to improve patient sleep, or to achieve other therapeutic goals.
摘要翻译：方法和系统涉及协调用于治疗无序呼吸的治疗。无序呼吸治疗可能包括心脏电刺激治疗和外部呼吸治疗以及治疗患者无序呼吸的其他疗法。可以协调递送给患者的治疗以增强治疗的有效性，减少治疗相互作用，改善患者睡眠或实现其他治疗目标。

77. 发明授权

US08929983B2 Reverse hysteresis and mode switching for intermittent pacing therapy 有权
标题翻译：间歇性起搏治疗的反向滞后和模式切换
公开(公告)号：US08929983B2
公开(公告)日：2015-01-06
申请号：US12615050
申请日：2009-11-09
申请人： Shantha Arcot-Krishnamurthy , Gary T. Seim , Kent Lee , Yanting Dong , Allan C. Shuros , David L. Whitehouse
发明人： Shantha Arcot-Krishnamurthy , Gary T. Seim , Kent Lee , Yanting Dong , Allan C. Shuros , David L. Whitehouse
IPC分类号： A61N1/368 , A61N1/362
CPC分类号： A61N1/3627 , A61N1/3688
摘要： Cardioprotective pre-excitation pacing may be applied to stress or de-stress a particular myocardial region delivering of pacing pulses in a manner that causes a dyssynchronous contraction. Such dyssynchronous contractions are responsible for the desired cardioprotective effects of pre-excitation pacing. A method and device for applying reverse hysteresis and mode switching to the delivery of such cardioprotective pacing are described.
摘要翻译：心脏保护性预激发起搏可用于以导致同步收缩的方式对起搏脉冲递送的特定心肌区域应力或去应激。这种异常收缩负责预激励起搏的所需心脏保护作用。描述了一种用于将逆向滞后和模式切换应用于这种心脏保护起搏的递送的方法和装置。

78. 发明授权

US08914113B2 Method and apparatus for inspiratory muscle stimulation using implantable device 有权
标题翻译：使用可植入装置吸气肌肉刺激的方法和装置
公开(公告)号：US08914113B2
公开(公告)日：2014-12-16
申请号：US13412282
申请日：2012-03-05
申请人： Yi Zhang , Shantha Arcot-Krishnamurthy , Lili Liu , Kenneth C. Beck , Kent Lee , Jonathan Kwok , Zheng Lin
发明人： Yi Zhang , Shantha Arcot-Krishnamurthy , Lili Liu , Kenneth C. Beck , Kent Lee , Jonathan Kwok , Zheng Lin
IPC分类号： A61N1/365 , A61N1/36 , A61N1/05
CPC分类号： A61N1/3601 , A61N1/0558
摘要： An inspiratory muscle stimulation system uses an implantable medical device to deliver stimulation to control diaphragmatic contractions for slower and deeper breathing, thereby conditioning and strengthening inspiratory muscles. In various embodiments, respiratory and/or cardiac performance are monitored for controlling parameters of the stimulation.
摘要翻译：吸气肌肉刺激系统使用可植入医疗装置来输送刺激以控制膈肌收缩以减慢和深呼吸，从而调节和加强吸气肌肉。在各种实施例中，监测呼吸和/或心脏性能以控制刺激的参数。

79. 发明授权

US08751467B2 Method and apparatus for quickly accessing backing store metadata 有权
标题翻译：用于快速访问后备存储元数据的方法和设备
公开(公告)号：US08751467B2
公开(公告)日：2014-06-10
申请号：US11624524
申请日：2007-01-18
申请人： Kent Lee
发明人： Kent Lee
IPC分类号： G06F17/30
CPC分类号： G06F12/126 , G06F11/1666 , G06F11/2056 , G06F11/2089 , G06F12/0804 , G06F12/0866 , G06F2212/466
摘要： A method, device, and system are provided for accessing metadata in a data storage system. More specifically, a requesting application requests a cache application to allocate a cache page to retrieve metadata from a storage device. After metadata is written to the cache page, the cache page is locked by the requesting application. The cache page is maintained in a locked state by the requesting application. This allows the data stored within the cache page to be quickly accessed and updated by the requesting application without waiting for the cache page to be written back to the storage device after every update to the cache page occurs.
摘要翻译：提供了一种用于访问数据存储系统中的元数据的方法，设备和系统。更具体地，请求应用请求高速缓存应用分配高速缓存页面以从存储设备检索元数据。元数据写入缓存页后，缓存页被请求应用程序锁定。缓存页面由请求应用程序保持在锁定状态。这允许存储在高速缓存页面内的数据被请求应用程序快速访问和更新，而不必在每次更新到高速缓存页面之后等待缓存页面被写回到存储设备。

80. 发明授权

US08656123B2 Snapshot preserved data cloning 有权
标题翻译：快照保存数据克隆
公开(公告)号：US08656123B2
公开(公告)日：2014-02-18
申请号：US12540243
申请日：2009-08-12
申请人： Kent Lee
发明人： Kent Lee
IPC分类号： G06F12/16 , G06F11/14 , G06F11/20
CPC分类号： G06F11/1446 , G06F3/0605 , G06F3/0617 , G06F3/065 , G06F3/067 , G06F11/2007 , G06F11/2089 , G06F2201/84
摘要： A method and device for cloning snapshots is provided. A new snapshot can be created by cloning an existing snapshot. The clone snapshot may use the preserved data of the existing snapshot, thereby obviating the need to copy the preserved data. Additionally, the clone snapshot may be created with a data structure for storing write data. Since the clone snapshot initially has no write data to store, the creation of the entire clone snapshot can be accomplished without copying any preserved data or write data from the existing snapshot, thereby increasing the efficiency with which a clone snapshot can be created.
摘要翻译：提供了克隆快照的方法和设备。可以通过克隆现有快照来创建新的快照。克隆快照可以使用现有快照的保留数据，从而避免复制保留数据的需要。另外，克隆快照可以用用于存储写入数据的数据结构来创建。由于克隆快照最初没有存储的写入数据，因此可以在不复制任何保留的数据或从现有快照写入数据的情况下完成整个克隆快照的创建，从而提高可以创建克隆快照的效率。

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