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71. 发明授权

US6009877A Method for treating a sphincter 失效
公开(公告)号：US6009877A
公开(公告)日：2000-01-04
申请号：US026296
申请日：1998-02-19
申请人： Stuart D. Edwards
发明人： Stuart D. Edwards
IPC分类号： A61B17/00 , A61B5/00 , A61B5/04 , A61B5/0488 , A61B5/053 , A61B8/00 , A61B17/22 , A61B17/42 , A61B18/00 , A61B18/02 , A61B18/04 , A61B18/12 , A61B18/14 , A61B18/18 , A61F2/958 , A61F7/12 , A61M3/02 , A61M16/04 , A61M31/00 , A61N1/05 , A61N1/06 , A61N1/08 , A61N1/40 , A61B17/39
CPC分类号： A61B5/04884 , A61B18/00 , A61B18/1206 , A61B18/1477 , A61B18/148 , A61B18/1485 , A61B18/1492 , A61M16/0481 , A61N1/056 , A61N1/06 , A61N1/08 , A61N1/40 , A61B18/18 , A61B18/1815 , A61B2017/00022 , A61B2017/00084 , A61B2017/00106 , A61B2017/003 , A61B2017/00867 , A61B2017/22062 , A61B2017/22072 , A61B2017/4216 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00065 , A61B2018/00077 , A61B2018/00083 , A61B2018/00113 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00232 , A61B2018/00267 , A61B2018/00291 , A61B2018/00494 , A61B2018/00553 , A61B2018/00559 , A61B2018/00577 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00738 , A61B2018/00744 , A61B2018/00755 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00827 , A61B2018/00839 , A61B2018/00869 , A61B2018/00875 , A61B2018/00886 , A61B2018/00892 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/00982 , A61B2018/0262 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/1425 , A61B2018/1467 , A61B2018/1472 , A61B2090/3614 , A61B2090/3782 , A61B2218/002 , A61B5/01 , A61B5/0535 , A61B8/00 , A61F7/12 , A61M2025/1052 , A61M2025/1086 , A61M25/1002 , A61M3/0279 , C08L2201/12
摘要： A method of treating a sphincter that provides an expandable basket structure with a first energy delivery device. The basket structure is introduced in a sphincter. The first energy delivery device is advanced from the basket structure into an interior of the sphincter. Sufficient energy is delivered from the first energy delivery device to create a desired tissue effect in the sphincter. Thereafter, the basket structure is removed from the sphincter.

72. 发明授权

US5879349A Apparatus for treatment of air way obstructions 失效
标题翻译：用于治疗空气障碍物的装置
公开(公告)号：US5879349A
公开(公告)日：1999-03-09
申请号：US695802
申请日：1996-08-12
申请人： Stuart D. Edwards
发明人： Stuart D. Edwards
IPC分类号： A61B17/24 , A61B5/04 , A61B17/00 , A61B17/30 , A61B18/00 , A61B18/12 , A61B18/14 , A61B18/18 , A61B18/20 , A61B18/22 , A61M1/00 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/36
CPC分类号： A61B5/04 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61N1/06 , A61N1/403 , A61N5/045 , A61B17/24 , A61B18/1402 , A61B18/1442 , A61B18/20 , A61B18/22 , A61B2017/00026 , A61B2017/00084 , A61B2017/00296 , A61B2017/248 , A61B2017/306 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00101 , A61B2018/00196 , A61B2018/00261 , A61B2018/00291 , A61B2018/00327 , A61B2018/00636 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00744 , A61B2018/00773 , A61B2018/00791 , A61B2018/00797 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/00982 , A61B2018/1425 , A61B2090/3782 , A61B2218/002 , A61B2218/003 , A61B5/415 , A61M2025/0096 , A61N5/04
摘要： An apparatus that reduces a volume of a selected site in an interior of the tongue includes a handpiece and an electrode at least partially positioned in the interior of the handpiece. The electrode includes an electrode electromagnetic energy delivery surface and is advance able from the interior of the handpiece into the interior of the tongue. An electrode advancement member is coupled to the electrode and configured to advance the electrode an advancement distance in the interior of the tongue. The advancement distance is sufficient for the electrode electromagnetic energy delivery surface to deliver electromagnetic energy to the selected tissue site and reduce a volume of the selected site without damaging a hypoglossal nerve. A cable is coupled to the electrode.
摘要翻译：减少舌头内部的选定部位的体积的装置包括至少部分地定位在手持件内部的手持件和电极。电极包括电极电磁能量输送表面，并且能够从手持件的内部进入舌头的内部。电极推进构件联接到电极并且被配置为使电极在舌头的内部中前进距离。前进距离足以使电极电磁能量输送表面向所选择的组织部位输送电磁能量，并减少选定部位的体积而不损伤舌下神经。电缆耦合到电极。

73. 发明授权

US5871443A Cardiac mapping and ablation systems 失效
公开(公告)号：US5871443A
公开(公告)日：1999-02-16
申请号：US747811
申请日：1996-11-14
申请人： Stuart D. Edwards , Thomas F. Kordis , David K. Swanson
发明人： Stuart D. Edwards , Thomas F. Kordis , David K. Swanson
IPC分类号： A61B5/042 , A61B18/14 , A61B18/18 , A61L29/08 , A61L29/14 , A61L31/10 , A61L31/14 , A61N1/05 , A61B5/04
CPC分类号： A61B5/6856 , A61B5/0422 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , A61B18/14 , A61B18/18 , A61B2562/0209 , A61B2562/043 , Y10T29/49002 , Y10T29/49117
摘要： An electrode assembly for use in interventricular cardiac mapping includes one or more elongated splines each of which carries a plurality of spaced apart electrodes thereon. The body of each spline is formed of a plurality of alternating electrically conductive layers and the electrically non-conductive layers. A separate electrically conductive pathway is provided to connect each of the electrodes to a different one of the conductive layers. Each of the layers is electrically connected to an electrical signal processing device so that signals provided by each of the electrodes can be processed.

74. 发明授权

US5843077A Minimally invasive apparatus for internal ablation of turbinates with surface cooling 失效
标题翻译：用于表面冷却的鼻甲内部消融的微创装置
公开(公告)号：US5843077A
公开(公告)日：1998-12-01
申请号：US790173
申请日：1997-01-29
申请人： Stuart D. Edwards
发明人： Stuart D. Edwards
IPC分类号： A61B17/00 , A61B17/42 , A61B18/00 , A61B18/04 , A61B18/14 , A61B18/18 , A61F2/958 , A61M3/02 , A61M16/04 , A61N1/06 , A61N1/08 , A61N5/04 , A61B17/36
CPC分类号： A61B18/1477 , A61B18/148 , A61B18/1485 , A61B18/1492 , A61M16/0481 , A61N1/06 , A61N1/08 , A61B18/18 , A61B2017/00084 , A61B2017/00106 , A61B2017/4216 , A61B2018/00029 , A61B2018/00065 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00261 , A61B2018/00559 , A61B2018/00577 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00761 , A61B2018/00791 , A61B2018/00827 , A61B2018/00869 , A61B2018/00875 , A61B2018/00886 , A61B2018/00892 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/00982 , A61B2018/046 , A61B2018/124 , A61B2018/1472 , A61B2218/002 , A61M2025/1052 , A61M2025/1086 , A61M25/1002 , A61M3/0279 , A61N5/04
摘要： A method and apparatus for ablating at least a portion of a nasal concha. The apparatus includes a catheter having a distal portion with a dimension configured for positioning through a nostril of a patient into a nasal meatus adjacent a nasal concha, and an energy delivery device coupled to the catheter distal portion including one or more energy delivering probes extendable from the catheter distal portion a sufficient distance to be inserted into an interior of the nasal concha to deliver ablative energy therein. The distal portion of the apparatus may also include an expandable member, expansion of the expandable member within the nasal meatus immobilizing the distal portion within the nasal meatus.
摘要翻译：一种用于消融鼻内耳的至少一部分的方法和装置。该装置包括具有远端部分的导管，该远端部分具有被配置用于将患者的鼻孔定位成邻近鼻塞的鼻腔的尺寸，以及联接到导管远端部分的能量输送装置，其包括一个或多个能够从导管远端部分具有足够的距离以插入鼻内耳内部以在其中传递消融能量。装置的远端部分还可以包括可扩张构件，将可扩张构件膨胀在鼻腔内，将远端部分固定在鼻腔内。

75. 发明授权

US5792173A Wound closure hemostasis device 失效
标题翻译：伤口闭合止血装置
公开(公告)号：US5792173A
公开(公告)日：1998-08-11
申请号：US500381
申请日：1995-07-10
申请人： Richard C. Breen , Peter H. Lazarus , Stuart D. Edwards , Edward J. Gough
发明人： Richard C. Breen , Peter H. Lazarus , Stuart D. Edwards , Edward J. Gough
IPC分类号： A61B17/12 , A61B17/132 , A61B17/135 , A61B17/00
CPC分类号： A61B17/135 , A61B17/1325
摘要： A wound closure, hemostasis device, such as a femoral hemostat, includes an inflatable balloon with an inflation and deflation outlet. A placement patch includes an aperture for receiving the inflation and deflation outlet. The inflatable balloon is coupled to the placement patch and positioned adjacent to a wound site or a bleeding vessel. A belt straps through the placement patch and around the patient's body or a patient's appendage and holds the placement patch at the wound site or bleeding vessel. An inflation tube is coupled to the inflation and deflation outlet. An inflation apparatus is coupled to the inflation and deflation outlet.
摘要翻译：创伤闭合器，止血装置，例如股骨止血器，包括具有充气和放气口的充气气囊。放置贴片包括用于接收充气和放气口的孔。可充气气球与放置贴片联接并定位成与伤口部位或出血血管相邻。皮带穿过贴片并围绕患者的身体或患者的附属物，并将放置贴片保持在伤口部位或出血血管。充气管连接到充气和通气口。通货膨胀设备与通货膨胀和通货紧缩出口相结合。

76. 发明授权

US5743870A Ablation apparatus and system for removal of soft palate tissue 失效
标题翻译：用于消除软腭组织的消融装置和系统
公开(公告)号：US5743870A
公开(公告)日：1998-04-28
申请号：US643524
申请日：1996-05-06
申请人： Stuart D. Edwards
发明人： Stuart D. Edwards
IPC分类号： A61B5/04 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/30 , A61B18/00 , A61B18/12 , A61B18/14 , A61B18/18 , A61B18/20 , A61B18/22 , A61B19/00 , A61M1/00 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/39
CPC分类号： A61B5/04 , A61B18/1442 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61N1/06 , A61N1/403 , A61N5/045 , A61B17/24 , A61B18/1402 , A61B18/20 , A61B18/22 , A61B2017/00026 , A61B2017/00084 , A61B2017/00296 , A61B2017/22077 , A61B2017/248 , A61B2017/306 , A61B2018/00011 , A61B2018/00023 , A61B2018/00101 , A61B2018/00261 , A61B2018/00291 , A61B2018/00327 , A61B2018/00636 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00744 , A61B2018/00773 , A61B2018/00791 , A61B2018/00797 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/00982 , A61B2018/1425 , A61B2090/3782 , A61B2218/002 , A61B2218/003 , A61B90/361 , A61M2025/0096 , A61N5/04
摘要： An ablation apparatus suitable for the ablation of soft palate tissue, including but not limited to the uvula, includes a cannula with a distal end and a proximal end and a lumen. A vacuum assisted retainer device is coupled to the cannula distal end. The vacuum retainer member includes a uvula receiving member configured to retain at least a portion of the uvula with the application of vacuum. An electromagnetic electrode is coupled to an electromagnetic energy source. A vacuum source is coupled to the uvula receiving member.
摘要翻译：适于消融软腭组织的消融装置包括但不限于小疱，包括具有远端和近端以及内腔的套管。真空辅助保持装置联接到套管远端。真空保持器构件包括构造成在应用真空的情况下保持至少一部分小叶的尿道接收构件。电磁电极耦合到电磁能源。真空源耦合到尿道接收构件。

77. 发明授权

US5486161A Medical probe device and method 失效
标题翻译：医用探针装置及方法
公开(公告)号：US5486161A
公开(公告)日：1996-01-23
申请号：US148441
申请日：1993-11-08
申请人： Ronald G. Lax , Stuart D. Edwards , Hugh R. Sharkey
发明人： Ronald G. Lax , Stuart D. Edwards , Hugh R. Sharkey
IPC分类号： A61B1/018 , A61B10/00 , A61B10/02 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/34 , A61B18/00 , A61B18/12 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M1/00 , A61M25/00 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/39
CPC分类号： A61B18/00 , A61B10/0233 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61M25/0136 , A61N1/06 , A61N1/403 , A61B18/14 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00123 , A61B2017/00181 , A61B2017/00194 , A61B2017/00274 , A61B2017/00292 , A61B2017/00296 , A61B2017/003 , A61B2017/00867 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00023 , A61B2018/00083 , A61B2018/00095 , A61B2018/00101 , A61B2018/00196 , A61B2018/0022 , A61B2018/00291 , A61B2018/00327 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/378 , A61B2090/3782 , A61B2090/3786 , A61B2090/3925 , A61B2218/003 , A61F2007/0054 , A61M2025/0089 , A61M2025/0096 , A61M2025/018 , A61M25/0068 , A61M25/0082 , A61N5/04
摘要： A medical ablation device comprising a flexible RF electrode wire or tube, the terminal portion thereof extending through an insulating sleeve axially moveable thereon. The electrode and surrounding sleeve extend through a portion of a rigid tube having a distal end adapted to be inserted into the body of a patient. Tabs are attached to the proximal end of the sleeve and electrode for advancing them together from the terminal end of the tube, for retracting the sleeve from the distal end of the electrode to expose a predetermined area of electrode surface, and for retracting them together into the terminal end of the tube. The electrode can also be a hollow tube, the proximal end thereof being adapted to be connected to a suction source for aspiration of tissue adjacent its distal end or it can optionally contain a fiber optic, the end thereof being enclosed within the tube and closely adjacent its distal end. In one embodiment, the electrode is a hollow electrode tube of highly flexible memory metal, preformed to have a curved memory configuration. The portion of the electrode tube and its surrounding sleeve extending beyond the distal end of the outer tube adopts the curved memory configuration, causing it to follow a curved path when extended through intervening tissue to reach a target tissue to be ablated.
摘要翻译：一种医疗消融装置，其包括柔性RF电极线或管，其端部延伸穿过其上可轴向移动的绝缘套筒。电极和周围套筒延伸穿过具有适于插入患者体内的远端的刚性管的一部分。凸片附接到套筒的近端和电极，用于将它们从管的终端推进到一起，用于将套筒从电极的远端缩回以暴露电极表面的预定区域，并将它们一起收回到管末端。电极也可以是中空管，其近端适于连接到抽吸源，用于抽吸邻近其远端的组织，或者它可以可选地包含光纤，其端部封闭在管内并且紧邻其远端在一个实施例中，电极是高度柔性的存储金属的中空电极管，预成形为具有弯曲的存储器配置。延伸超过外管远端的电极管及其周围的套筒的部分采用弯曲的记忆结构，使其在延伸穿过介入组织到达要消融的靶组织时遵循弯曲的路径。

78. 发明授权

US5472441A Device for treating cancer and non-malignant tumors and methods 失效
标题翻译：用于治疗癌症和非恶性肿瘤的装置及方法
公开(公告)号：US5472441A
公开(公告)日：1995-12-05
申请号：US208676
申请日：1994-03-11
申请人： Stuart D. Edwards , Ronald G. Lax
发明人： Stuart D. Edwards , Ronald G. Lax
IPC分类号： A61B18/00 , A61B18/14 , A61B18/18 , A61M1/00 , A61M3/02 , A61M25/00 , A61N5/02 , A61N5/04 , A61B17/36
CPC分类号： A61B18/1477 , A61B18/1482 , A61B18/18 , A61B18/1815 , A61N5/02 , A61N5/045 , A61B18/14 , A61B18/1402 , A61B18/1492 , A61B2018/00011 , A61B2018/00196 , A61B2018/00452 , A61B2018/00476 , A61B2018/00577 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00761 , A61B2018/00779 , A61B2018/00791 , A61B2018/00875 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1425 , A61B2018/1435 , A61B2018/162 , A61B2218/002 , A61M25/007 , A61M3/0279 , A61N5/04
摘要： A method of this invention for treating body tissues containing cancerous cells or non-malignant tumors with RF ablation, alone or in combination with systemic or localized chemotherapy comprising introducing a stylet comprising an electrode surface and a sleeve longitudinally moveable thereon into the vicinity of the body tissues, retracting the sleeve from a portion of the electrode surface, and supplying RF power to the electrode surface sufficient to heat the tissue to a temperature of above about 45.degree. C. for a time to cause reduction of tissue mass in the vicinity of the electrode. The RF power supplied to the electrode surface is sufficient to effect a desiccated fluid diffusion barrier capsule surrounding the body tissue being treated. The stylet can include a hollow tube having fluid distribution ports therein, and the method can include the step of passing fluid through one or more distribution ports into the body tissue being treated. The fluid can be saline or a chemotherapeutic fluid such as liquid or gas containing a cytotoxic agent, for example. The fluid can be administered in a variety of procedures. The fluid can be passed through a distribution port into the body tissue before, during and/or after the RF power is supplied to the electrode surface, for example. Preferably, the fluid is introduced after a barrier capsule has been formed. The devices comprises electrodes havming a hollow core and a closed sharpened distal tip. The electrode has a plurality of fluid distribution ports therein for distribution of fluid treatment agents into the tissue.
摘要翻译：本发明的方法，用于单独或与全身或局部化疗组合，用RF消融治疗含有癌细胞或非恶性肿瘤的身体组织，包括将包含电极表面和纵向可移动到其上的套管引入身体附近组织，从电极表面的一部分缩回套筒，并将RF功率提供给电极表面，足以将组织加热至高于约45℃的温度一段时间，以使组织块在附近的电极。提供给电极表面的RF功率足以实现围绕被处理的身体组织的干燥的流体扩散阻挡胶囊。探针可以包括其中具有流体分配端口的中空管，并且该方法可以包括使流体通过一个或多个分配端口进入被处理的身体组织的步骤。流体可以是例如盐水或化疗液体，例如含有细胞毒性剂的液体或气体。流体可以以各种方法给药。例如，在将RF功率提供给电极表面之前，期间和/或之后，流体可以通过分配端口进入身体组织。优选地，在形成阻挡胶囊之后引入流体。这些装置包括电极，该电极覆盖中空芯和封闭的锋利的远端尖端。电极在其中具有多个流体分配端口，用于将流体处理剂分配到组织中。

79. 发明授权

US5368592A Articulated systems for cardiac ablation 失效
标题翻译：用于心脏消融的铰接系统
公开(公告)号：US5368592A
公开(公告)日：1994-11-29
申请号：US126126
申请日：1993-09-23
申请人： Roger A. Stern , Stuart D. Edwards , Jerome Jackson
发明人： Roger A. Stern , Stuart D. Edwards , Jerome Jackson
IPC分类号： A61M25/01 , A61N1/40
CPC分类号： A61M25/0147 , Y10T403/32311
摘要： An improved assembly for steering and orienting a functional element at the distal end of a catheter tube holds the functional element with its major axis aligned with the axis of the catheter tube for convenient steering to a tissue site. The mechanism can also pivot the functional element in response to an external force to orient the major axis of the functional element generally parallel to the plane of the tissue site, without bending the catheter tube.
摘要翻译：用于在导管管的远端处转向和定向功能元件的改进的组件保持功能元件，其主轴与导管管的轴线对准，以便于转向组织部位。机构还可以响应于外力使功能元件枢转，以使功能元件的长轴大致平行于组织部位的平面定向，而不弯曲导管。

80. 发明授权

US5275162A Valve mapping catheter 失效
标题翻译：阀门定位导管
公开(公告)号：US5275162A
公开(公告)日：1994-01-04
申请号：US982233
申请日：1992-11-25
申请人： Stuart D. Edwards , Russell B. Thompson , Rand T. Pugmire
发明人： Stuart D. Edwards , Russell B. Thompson , Rand T. Pugmire
IPC分类号： A61B5/042
CPC分类号： A61B5/042 , A61B5/0422 , A61B2562/0209 , A61B2562/043
摘要： A method and apparatus for contacting heart valve tissue with a catheter tip electrode adapted for atrioventricular (AV) node mapping and modification is provided. The tip is conformed to rest stably and comfortably on a cardiac valve such as the mitral or tricuspid valve. The tip has a peanut shape consisting of two electrode lobes joined by a narrower connecting piece. The tip rests on the valve at the connecting piece and is secured by the adjoining lobes. The connecting piece itself may either be insulating or electrically conductive. The catheter may also include standard mapping and/or pacing electrodes. The catheter may further include a steering mechanism for positioning the catheter at various treatment sites in the heart.
摘要翻译：提供一种用于使心脏瓣膜组织与适用于房室（AV）节点映射和修改的导管尖端电极接触的方法和装置。尖端符合在诸如二尖瓣或三尖瓣的心脏瓣膜上稳定和舒适地平稳。尖端具有由两个由较窄连接件连接的电极凸片组成的花生形状。尖端位于连接件上的阀上，并由相邻的凸角固定。连接件本身可以是绝缘的或导电的。导管还可以包括标准贴图和/或起搏电极。导管还可以包括用于将导管定位在心脏中的各种治疗部位的转向机构。

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