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    • 68. 发明申请
    • COMPOSITIONS AND METHODS FOR ENHANCING ODORANT RECEPTOR ACTIVITY
    • 用于增强气味受体活性的组合物和方法
    • US20130004983A1
    • 2013-01-03
    • US13513600
    • 2010-12-06
    • Hiroaki MatsunamiYun Li
    • Hiroaki MatsunamiYun Li
    • C12N5/071C12Q1/02
    • C12Q1/6881C07K14/70571C12Q2600/136C12Q2600/156
    • The present invention relates to polypeptides capable of modulating odorant receptor activation. In particular, the present invention provides polypeptides (e.g., type 3 muscarinic actetylcholine receptor M3) capable of enhancing odorant receptor activation. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, the present invention provides methods of screening for polypeptide polymorphisms and mutations associated with odorant receptor activation (e.g., polymorphisms and mutations associated with muscarinic actetylcholine receptor polypeptides (e.g., M1, M2 M3, M4, M5)), as well as methods of screening for therapeutic agents, ligands, and modulators of such proteins.
    • 本发明涉及能够调节气味受体活化的多肽。 特别地,本发明提供能够增强加味剂受体活化的多肽(例如,3型毒蕈碱性乙酰胆碱受体M3)。 本发明还提供了检测各种加臭剂受体特异性配体的测定。 另外,本发明提供筛选多肽多态性和与气味受体激活相关的突变的方法(例如,与毒蕈碱性乙酰胆碱受体多肽(例如,M1,M2 M3,M4,M5)相关的多态性和突变),以及 筛选这些蛋白质的治疗剂,配体和调节剂。
    • 70. 发明授权
    • Electronic control fuel save clutch device for vehicle
    • 汽车电子控制节油离合器装置
    • US07901322B2
    • 2011-03-08
    • US12093647
    • 2005-11-15
    • Waikei HuenYun Li
    • Waikei HuenYun Li
    • B60K26/00
    • B60K26/04B60W10/06B60W10/184B60W30/18109B60W2540/10B60W2540/12B60W2710/0605Y02T10/52Y02T10/84Y10T477/747Y10T477/75
    • The present invention relates to an electronic control fuel saving clutch device for a vehicle, comprising: an electronic control clutch (7), a brake switch (8), an accelerator sensor (9) and an electromagnetic fuel line throttle valve (G) for opening and closing the accelerated fuel supply; the electronic control clutch and the electromagnetic fuel line throttle valve are controlled by the brake switch and signals emitted by the accelerator sensor, wherein when the brake switch is switched on, the electronic clutch is engaged, and the electromagnetic fuel line throttle valve is closed, and the engine is supplied only with the idle fuel supply; when the brake switch is switched off, if the accelerator sensor detects that the accelerator pedal (P) goes forward or keeps in a certain forward position, the electronic control clutch is engaged and the electromagnetic fuel line throttle valve is open, then the accelerating fuel supply is switched on, and the engine is supplied with the accelerating fuel supply; if the accelerator sensor detects that the accelerator pedal comes back or keeps in a certain back position, the electronic control clutch is disengaged, and the electromagnetic fuel line throttle valve is closed, then the accelerating fuel supply of the engine is cut off, and the engine is supplied only with the idle fuel supply.
    • 本发明涉及一种用于车辆的电子控制节油离合器装置,包括:电子控制离合器(7),制动开关(8),加速器传感器(9)和电磁燃料管路节流阀(G),用于 开启和关闭加速燃料供应; 电子控制离合器和电磁燃料管路节流阀由制动开关和加速器传感器发出的信号控制,其中当制动开关接通时,电子离合器接合,电磁燃料管路节流阀关闭, 并且发动机仅供应空闲燃料供应; 当制动开关关闭时,如果加速器传感器检测到加速器踏板(P)前进或保持在一定的前进位置,则电子控制离合器接合并且电磁燃料管路节流阀打开,然后加速燃料 供电被接通,并且发动机被供给加速燃料供应; 如果加速器传感器检测到加速器踏板返回或保持在一定的后退位置,则电子控制离合器分离,并且电磁燃料管路节流阀关闭,然后切断发动机的加速燃料供给, 发动机仅供应空闲燃料供应。