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61. 发明授权

US06964710B2 Method for cleaning of a measuring element passed over by a gas flow 失效
标题翻译：清洁由气流过去的测量元件的方法
公开(公告)号：US06964710B2
公开(公告)日：2005-11-15
申请号：US10606329
申请日：2003-06-25
申请人： Hans Hecht , Torsten Schulz , Thomas Lenzing , Klaus Reymann , Uwe Konzelmann
发明人： Hans Hecht , Torsten Schulz , Thomas Lenzing , Klaus Reymann , Uwe Konzelmann
IPC分类号： G01F15/12 , B08B3/12 , G01F1/68 , G01F1/684 , G01F1/692 , G01F1/696 , G01F1/698 , B08B7/02
CPC分类号： G01F1/6986 , G01F1/6845
摘要： A method for cleaning of a measuring element (1) passed over by a gas flow is arranged on a thin-walled membranous material (5). The measuring element (1) includes at least one heatable element (6, 7, 8; 10, 11), which is arranged on the membranous material, the membranous material being capable of vibrating. By means of a control apparatus (20) or a switching (22) associated with the measuring element, a periodic delivery of current (41, 42) in intervals takes place in this manner to at least one heatable element (6, 7, 8; 10, 11) of the measuring element (1) and thereby produces vibrations. Alternatively, vibrations of the membranous material (5) can be produced by special vibration exciters or by means of ultrasonic coupling.
摘要翻译：用于清洁由气流流过的测量元件（1）的方法设置在薄壁膜材料（5）上。测量元件（1）包括至少一个布置在膜材料上的可加热元件（6,7,8,10,11），所述膜材料能够振动。通过与测量元件相关联的控制装置（20）或开关（22），电流（41,42）的间隔周期性地以这种方式发生到至少一个可加热元件（6,7,8 ; 10,11），从而产生振动。或者，膜材料（5）的振动可以通过特殊的振动激励器或通过超声波耦合来产生。

62. 发明授权

US06896855B1 Miniaturized temperature-zone flow reactor 失效
标题翻译：微型化温度区流量反应器
公开(公告)号：US06896855B1
公开(公告)日：2005-05-24
申请号：US09600694
申请日：1999-02-10
申请人： Johann Michael Köhler , Andreas Mokansky , Siegfried Poser , Torsten Schulz
发明人： Johann Michael Köhler , Andreas Mokansky , Siegfried Poser , Torsten Schulz
IPC分类号： B01J19/00 , B01L3/00 , B01L7/00 , B01J8/00 , B01J8/04
CPC分类号： B01L3/5027 , B01J19/0093 , B01L3/502707 , B01L3/502784 , B01L7/525 , B01L2300/0816 , B01L2300/0874 , B01L2300/0883 , B01L2300/1822 , B01L2300/1827 , B01L2300/1883
摘要： A miniaturized temperature-zone flow reactor, used for thermally controlled biochemical or molecular-biological processes, especially polymerase chain reaction (PCR) enables more efficient reactions by providing at least one closed flow path which is divided into three partial paths (A1 . . . An; B1 . . . Bn and BB1 . . . BBn−1; C1 . . . Cn) with the reactor having three substrate chips (A; B; C) which are made of a material having a high heat conductivity, and which have defined channel sections that are spaced apart relative to each other, and are connected by a connecting chip (V) made of a poor heat-conductive material. The substrate chips (A; B; C) are maintained at different temperatures by various means, including the use of controlling heating elements in contact with the chips.
摘要翻译：用于热控生物化学或分子生物学过程，特别是聚合酶链式反应（PCR）的小型化温度 - 区域流动反应器通过提供至少一个闭合流动路径来实现更有效的反应，其被分成三个部分路径（A 1。（A; B; C）的反应器，由具有高热量的材料制成的反应器（A; B; C）; B 1 ... Bn和BB 1 ... BBn-1; C 1 ... Cn）导电性，并且具有相对于彼此间隔开的限定的通道部分，并且由由差的导热材料制成的连接芯片（V）连接。衬底芯片（A; B; C）通过各种方式保持在不同的温度，包括使用控制与芯片接触的加热元件。

63. 发明申请

US20050106592A1 Method for identifying a pharmacologically active substance 审中-公开
标题翻译：鉴定药理活性物质的方法
公开(公告)号：US20050106592A1
公开(公告)日：2005-05-19
申请号：US10919325
申请日：2004-08-17
申请人： Wolf-Dieter Schleuning , Torsten Schulz
发明人： Wolf-Dieter Schleuning , Torsten Schulz
IPC分类号： C12Q1/68 , G01N33/48 , G01N33/50 , G06F19/00
CPC分类号： C12N15/1089
摘要： Method for identifying a novel biologically active substance, which is based on defining the targeted property of the substance and selecting a reference organism, naturally displaying the targeted property.
摘要翻译：用于鉴定新的生物活性物质的方法，其基于定义物质的目标性质并选择参考生物体，自然地显示目标性质。

64. 发明申请

US20050047973A1 Device for holding a substance library carrier 审中-公开
标题翻译：持有物质库载体的装置
公开(公告)号：US20050047973A1
公开(公告)日：2005-03-03
申请号：US10820269
申请日：2004-04-08
申请人： Torsten Schulz , Eugen Ermantraut , Thomas Ullrich , Thomas Ellinger , Joachim Fischer , Thomas Kaiser , Klaus-Peter Mobius , Siegfried Poser , Jens Tuchscheerer , Martin Zieren
发明人： Torsten Schulz , Eugen Ermantraut , Thomas Ullrich , Thomas Ellinger , Joachim Fischer , Thomas Kaiser , Klaus-Peter Mobius , Siegfried Poser , Jens Tuchscheerer , Martin Zieren
IPC分类号： G01N33/53 , B01J19/00 , B01L3/00 , B01L7/00 , C12M1/00 , C12N15/09 , C12Q1/68 , G01N33/566 , G01N37/00 , B01L9/00
CPC分类号： B01L7/52 , B01J2219/00527 , B01J2219/00531 , B01J2219/00596 , B01J2219/00605 , B01J2219/00659 , B01J2219/00722 , B01J2219/00725 , B01L3/502715 , B01L2200/025 , B01L2200/027 , B01L2200/10 , B01L2200/141 , B01L2200/147 , B01L2300/044 , B01L2300/0636 , B01L2300/0877 , B01L2300/1805
摘要： Disclosed are devices for holding a substance library carrier, and which are useful in conducting reactions in which binding between complementary molecules is measured qualitatively or quantitatively. Also disclosed are methods for conducting such reactions in the device.
摘要翻译：公开了用于保存物质文库载体的装置，其可用于进行定性或定量测量互补分子之间的结合的反应。还公开了在该装置中进行这种反应的方法。

65. 发明授权

US06854325B2 Sensor chip having potential surfaces for avoiding contaminant 失效
标题翻译：传感器芯片具有防止污染的潜在表面
公开(公告)号：US06854325B2
公开(公告)日：2005-02-15
申请号：US10311404
申请日：2002-04-17
申请人： Uwe Konzelmann , Torsten Schulz
发明人： Uwe Konzelmann , Torsten Schulz
IPC分类号： G01P5/12 , G01F1/684 , G01F1/692 , G01K7/18 , G01F1/68
CPC分类号： G01F1/6845
摘要： A sensor chip having at least upstream from the sensor region, at least one potential surface that, by electrical interaction with the contaminants in the flowing medium, prevents precipitation in the sensor region.
摘要翻译：传感器芯片至少具有从传感器区域的上游，至少一个电势表面，通过与流动介质中的污染物的电相互作用，防止传感器区域中的沉淀。

66. 发明授权

US06821692B1 Kind of thin films for microsystem technology and microstructuring and their use 失效
标题翻译：用于微系统技术和微结构化的薄膜及其用途
公开(公告)号：US06821692B1
公开(公告)日：2004-11-23
申请号：US09230975
申请日：1999-02-04
申请人： Eugen Ermantraut , Johann Michael Köhler , Torsten Schulz , Klaus Wohlfart , Stefan Wölfl
发明人： Eugen Ermantraut , Johann Michael Köhler , Torsten Schulz , Klaus Wohlfart , Stefan Wölfl
IPC分类号： G03F7023
CPC分类号： H01L21/02118 , B01J19/0046 , B01J2219/00527 , C12Q1/002 , H01L21/02282 , H01L21/312
摘要： The present invention relates to novel thin layers for microsystem techniques and microstructuring. It is an object of the invention to provide thin layers which can be manufactured under less problems and more economically than the previous conventional layers, and which permit the use of existing technologies for microstructuring. The object is realized in that the thin layer is formed of an enzymatically degradable biopolymer in a range of layer thicknesses of from 30 nm to 3 &mgr;m. Biopolymeric thin layers manufactured according to the invention permit their application, after a respective structurizing, as test assays or in setting up substance libraries.
摘要翻译：本发明涉及用于微系统技术和微结构化的新型薄层。本发明的一个目的是提供薄层，其可以在比以前的常规层更少的问题和更经济地制造，并且允许使用现有的技术来进行微结构化。实现目的在于，薄层由层压厚度为30nm至3μm范围内的可酶促降解的生物聚合物形成。根据本发明生产的生物聚合物薄层允许其在各自的结构化之后作为测试测定或在建立物质文库中的应用。

67. 发明授权

US5513006A Photo-thermal sensor including an expansion lens in a light beam path through a sample for determining the concentration of a compound in the sample 失效
标题翻译：光热传感器包括通过样品的光束路径中的膨胀透镜，用于确定样品中化合物的浓度
公开(公告)号：US5513006A
公开(公告)日：1996-04-30
申请号：US378566
申请日：1995-01-26
申请人： Torsten Schulz , Werner Faubel
发明人： Torsten Schulz , Werner Faubel
IPC分类号： G01N21/17 , G01N21/41 , G01N25/16 , G01N21/00
CPC分类号： G01N21/171
摘要： In a photo-thermal sensor for determining the concentration of a compound in a sample which includes an excitation light source generating a first light beam of a wave length which is well absorbed by the compound to be determined, a modulator and an optical lens system disposed in the first light beam such that the first light beam is constricted at the location of the sample through which it is directed, a probe light source generating a second light beam extending at a right angle to the first light beam, a beam divider arranged at the intersection of the first and second light beams whereby part of the first light beam is deflected at one side of the beam divider and the second light beam passes through the beam divider such that both beams incide on the sample anti a photo-sensitive detector arranged in the light beam path behind the sample, a diaphragm is arranged in the beam path directly after the sample and an expansion lens adapted to expand the second light beam at the location of the sample to a diameter at least 5 times the diameter of the first light beam is disposed in the path of the second beam ahead of the beam divider for determining the loss of strength of the second light beam reaching the detector after passage through the sample and the diaphragm as an indication of the concentration of the compound in the sample.
摘要翻译：在用于确定样品中化合物的浓度的光热传感器中，所述光热传感器包括激发光源，所述激发光源产生被待确定的化合物很好地吸收的波长的第一光束，调制器和光学透镜系统被布置在所述第一光束中使得所述第一光束在所述第一光束被引导到的所述样品的位置处被收缩，产生与所述第一光束成直角延伸的第二光束的探测光源，布置在第一和第二光束的交叉点，使得第一光束的一部分在分束器的一侧偏转，并且第二光束通过分束器，使得两个光束入射到样品上，反射式光敏检测器被布置在采样后面的光束路径中，在样品之后的光束路径中布置有光阑，并且适于在该位置扩展第二光束的扩展透镜样品的直径至少为第一光束直径的5倍的直径设置在光束分离器前面的第二光束的路径中，以确定通过第一光束之后到达检测器的第二光束的强度损失样品和隔膜作为样品中化合物浓度的指示。

68. 发明授权

US09952153B2 Transformation of material into an optically modulating state via laser radiation 有权
公开(公告)号：US09952153B2
公开(公告)日：2018-04-24
申请号：US13991347
申请日：2011-12-02
申请人： Torsten Schulz , Daniel Weicherding
发明人： Torsten Schulz , Daniel Weicherding
IPC分类号： G01N15/06 , G01N33/00 , G01N33/48 , G01N21/64 , G02C7/02 , B01L3/00 , B41M5/24 , B41M5/26
CPC分类号： G01N21/6402 , B01L3/502707 , B01L2300/0654 , B01L2300/168 , B41M5/24 , B41M5/26 , B41M5/267 , G02C7/021
摘要： A method for the transformation of material (e.g. plastic material) into an optically modulating state via laser radiation is described. The optically modulating state may be a state in which light is emitted at a different wavelength than it is absorbed. The plastic material to may be a thermoplastic or elastomeric material, or an organic polymer selected from the group consisting of polyethylene, polypropylene, polystyrene, polycarbonate and polycycloolefin. The laser radiation may comprise the application of an amount of energy of about 0.1 nJoule/μm2 to about 100 μJoule/μm2 and/or may comprise a radiation of a wavelength of about 355 nm to about 1064 nm. The optically modulating state of the plastic material may absorb light in a wavelength spectrum of about 380 nm to about 540 nm and/or a wavelength spectrum of about 635 nm to about 655 nm. The optically modulating state of the plastic material may emit light in a wavelength spectrum of about 550 nm to about 800 nm. The transformation of the plastic material may comprise the generation of optically modulating elements on the surface of said plastic material, selected from the group comprising geometrical forms, geometrical pattern, spots, dots, lines, circles, squares, characters, symbols, drawings, barcode and datamatrixcode. The material may be used as component for the manufacture of a device, microfluidic device, system, cartridge or instrument. Based on the employment of the material the usability of a device or system and/or of any procedure, function or method carried out with it or in it may be determined and/or controlled.

69. 发明授权

US09367832B2 Synchronizing image data among applications and devices 有权
标题翻译：在应用程序和设备之间同步图像数据
公开(公告)号：US09367832B2
公开(公告)日：2016-06-14
申请号：US11325830
申请日：2006-01-04
申请人： Joseph J. Martin , Venkatachary Srinivasan , Jerald J. Singh , Marco Boerries , Torsten Schulz
发明人： Joseph J. Martin , Venkatachary Srinivasan , Jerald J. Singh , Marco Boerries , Torsten Schulz
IPC分类号： G06F15/16 , G06Q10/10 , G06F17/30 , G06Q10/06 , G06Q50/00
CPC分类号： G06Q10/10 , G06F17/3028 , G06Q10/06 , G06Q50/01
摘要： For providing synchronization of image data among diverse devices and applications, exemplary systems include a direct client application providing a user interface operable to allow a user to organize image data according to albums, and to select one or more albums for synchronization with one or more server interfaces that provide various image data manipulation, sharing, and features related thereto. Systems also include an intermediary system to assist in synchronization of select albums with handheld devices, and a notification server to provide scalable notifications of album updates made at server interfaces by users. Exemplary methods include steps providing for selection, from direct client applications, of albums to synchronize with devices, including handheld devices, and various steps of providing updates and notifications among appropriate system components.
摘要翻译：为了提供不同设备和应用之间的图像数据的同步，示例性系统包括提供可操作以允许用户根据相册组织图像数据的用户界面的直接客户端应用，并且选择一个或多个相册以与一个或多个服务器同步提供各种图像数据操作，共享和与其相关的特征的接口。系统还包括协助选择专辑与手持设备同步的中介系统，以及通知服务器，以提供在用户在服务器接口处制作的相册更新的可伸缩通知。示例性方法包括提供从直接客户端应用程序选择要与包括手持设备在内的设备同步的相册以及在适当的系统组件之间提供更新和通知的各种步骤的步骤。

70. 发明申请

US20150198604A1 ASSAYS 有权
标题翻译：测定
公开(公告)号：US20150198604A1
公开(公告)日：2015-07-16
申请号：US14564067
申请日：2014-12-08
申请人： Eugen Ermantraut , Thomas Kaiser , Jens Tuchscheerer , Vico Baier , Torsten Schulz , Anke Wostemeyer
发明人： Eugen Ermantraut , Thomas Kaiser , Jens Tuchscheerer , Vico Baier , Torsten Schulz , Anke Wostemeyer
IPC分类号： G01N33/58
CPC分类号： G01N33/58 , B01L3/50273 , B01L2200/025 , B01L2200/0684 , B01L2300/0816 , B01L2300/0887 , B01L2300/123 , B01L2400/0481 , Y10T436/25
摘要： A method for assaying a sample for each of multiple analytes is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone comprising a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple test zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte. Capillary structures of the devices or used in the methods may comprise a matrix and the devices may comprise control elements and methods for assaying of sample may use corresponding controlling activities.
摘要翻译：描述了用于分析多种分析物中的每一种的样品的方法。该方法包括使间隔开的测试区域的阵列与液体样品（例如全血）接触。测试区域设置在微流体装置的通道内。通道由至少一个柔性壁和可以是柔性的第二壁限定。每个测试区域包含对各个目标分析物特异的探针化合物。微流体装置被压缩以减小通道的厚度，其是通道内的壁的内表面之间的距离。每个分析物的存在通过光学检测在相应位置处的内表面之间的距离减小的多个测试区域中的每一个处的相互作用来确定。每个测试区域的相互作用表明样品中目标分析物的存在。装置的毛细结构或方法中使用的毛细管结构可以包括基质，并且装置可以包括控制元件和用于测定样品的方法可以使用相应的控制活动。

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