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61. 发明授权

US4732736A Analytical element for the detection hydrogen peroxide 失效
标题翻译：检测过氧化氢的分析元素
公开(公告)号：US4732736A
公开(公告)日：1988-03-22
申请号：US798562
申请日：1985-11-15
申请人： Morio Kobayashi , Kenichiro Okaniwa , Mikio Koyama , Kunihiro Furukawa , Soichi Zanma
发明人： Morio Kobayashi , Kenichiro Okaniwa , Mikio Koyama , Kunihiro Furukawa , Soichi Zanma
IPC分类号： C12Q1/00 , C12Q1/28 , G01N33/52 , G01N21/77 , G01N31/22
CPC分类号： G01N33/526 , C12Q1/28 , Y10S435/805 , Y10S436/904 , Y10T436/206664
摘要： An analytical element for the detection of hydrogen peroxide comprising a peroxidase-functional material, a hydrogen donor and a coupler, wherein the peroxidase-functional material and hydrogen donor are arranged so as to be separate from each other, for example in separate layers, but are made interactive by the application of a fluid sample.
摘要翻译：用于检测包含过氧化物酶功能材料，氢供体和成色剂的过氧化氢的分析元件，其中所述过氧化物酶功能材料和氢供体被布置为彼此分离，例如在单独的层中，但是通过应用流体样品进行交互。

62. 发明授权

US4613567A Immunoassay method for measuring immunological antigen in fluid sample 失效
标题翻译：用于测量流体样品中免疫学抗原的免疫测定方法
公开(公告)号：US4613567A
公开(公告)日：1986-09-23
申请号：US520072
申请日：1983-08-03
申请人： Seikichi Yasoshima , Mikio Koyama , Kenichiro Okaniwa
发明人： Seikichi Yasoshima , Mikio Koyama , Kenichiro Okaniwa
IPC分类号： G01N33/543 , C12Q1/00 , G01N21/64 , G01N33/558
CPC分类号： G01N33/54386 , Y10S435/805 , Y10S435/97 , Y10S436/807
摘要： There is disclosed an immunoassay comprising carrying out an immunological reaction by contacting a fluid sample with an element for immunoassay, having at least three layers of a first detecting layer, a blocking layer and a second detecting layer which are successively laminated, the element containing a substance capable of binding specifically to an immunologically active substance in a fluid sample only in either one of the first and the second detecting layers, and then measuring the detected quantities corresponding to the immunological reaction quantities from both of the first and the second detecting layers.The immunoassay by the use of the immunological analytical element according to this invention improves the precision immunoassay by measuring both of Bound and Free.
摘要翻译：公开了一种免疫测定，其包括通过使流体样品与用于免疫测定的元件接触而进行免疫反应，所述元件具有至少三层依次层压的第一检测层，阻挡层和第二检测层，所述元件含有能够仅在第一和第二检测层中的任一个中在流体样品中特异性结合免疫活性物质的物质，然后测量对应于来自第一和第二检测层的免疫反应量的检测量。通过使用根据本发明的免疫分析元件的免疫测定通过测量结合和自由来提高精确的免疫测定。

63. 发明授权

US4594224A Analytical element 失效
标题翻译：分析要素
公开(公告)号：US4594224A
公开(公告)日：1986-06-10
申请号：US597818
申请日：1984-04-09
申请人： Kenichiro Okaniwa , Shozo Kikugawa , Mikio Koyama
发明人： Kenichiro Okaniwa , Shozo Kikugawa , Mikio Koyama
IPC分类号： G01N31/22 , C12Q1/54 , G01N33/52 , G01N21/78
CPC分类号： G01N33/525 , C12Q1/54 , Y10S435/805
摘要： There is presented an improved simple quantitative analytical element for analysis of components in a body fluid such as blood, having a reagent layer constituted of a hydrophilic colloid containing at least one reagent reactive with a component in a liquid sample provided on a support, and also a development layer of a fibrous structure on the reagent layer on the opposite side to the support. A liquid sample can be distributed uniformly through the reagent layer to enable quantitative analysis.
摘要翻译：提出了一种用于分析诸如血液的体液中的组分的改进的简单定量分析元件，其具有由含有至少一种与在载体上提供的液体样品中的组分反应的试剂的亲水胶体构成的试剂层，以及在与载体相反的一侧上的试剂层上的纤维结构的显影层。液体样品可以均匀地分布在试剂层中，以进行定量分析。

64. 发明授权

US4486537A Analytical element and method of use 失效
标题翻译：分析要素和使用方法
公开(公告)号：US4486537A
公开(公告)日：1984-12-04
申请号：US419931
申请日：1982-09-20
申请人： Mikio Koyama , Kenichiro Okaniwa
发明人： Mikio Koyama , Kenichiro Okaniwa
IPC分类号： G01N31/22 , G01N33/52 , G01N21/78
CPC分类号： G01N33/525 , Y10S435/805
摘要： An analytical element comprising a light-transmissive and liquid-impervious support, at least one reagent layer containing at least one reagent which reacts with a component in a fluid sample and at least one development layer provided at a position on the reagent layer on the opposite side to that of the support for permitting the component in said fluid sample to permeate into the reagent layer, at least one layer of reagent layers being constituted of polymeric particulate units each having a core-shell multi-layer structure comprising a core, which is hydrophobic and substantially unswellable with a fluid sample, and a hydrophilic outer shell.
摘要翻译：一种分析元件，包括透光和液体不可渗透的载体，至少一个试剂层，其含有至少一种与流体样品中的组分反应的试剂，以及设置在相对的试剂层上的至少一个显影层与允许所述流体样品中的组分渗透到试剂层中的载体的一侧，至少一层试剂层由聚合物颗粒单元构成，每个聚合物颗粒单元均具有包含芯的核 - 壳多层结构，疏水性并且基本上不能与流体样品一起使用，以及亲水性外壳。

65. 发明授权

US4304850A Photographic element for color diffusion transfer process 失效
标题翻译：用于彩色扩散转印过程的照相元件
公开(公告)号：US4304850A
公开(公告)日：1981-12-08
申请号：US165060
申请日：1980-07-01
申请人： Mikio Koyama , Satoru Ikeuchi , Noboru Mizukura , Hideaki Iwama
发明人： Mikio Koyama , Satoru Ikeuchi , Noboru Mizukura , Hideaki Iwama
IPC分类号： C08F236/00 , C08F36/00 , C08F236/04 , G03C8/54 , G03C5/54 , G03C1/40 , G03C5/24
CPC分类号： G03C8/54 , Y10T428/31924 , Y10T428/31931
摘要： A photographic element for color diffusion transfer which includes a timing layer comprising a polymeric latex made up of (1) a conjugated diene monomer, (2) and ethylenically unsaturated acid monomer or salt, and (3) an ethylenically unsaturated monomer, which monomers are within certain percentage ranges.
摘要翻译：用于颜色扩散转印的照相元件，其包括由（1）共轭二烯单体，（2）和烯属不饱和酸单体或盐组成的聚合物胶乳的定时层，和（3）烯属不饱和单体，所述单体为在一定百分比范围内。

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