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    • 3. 发明授权
    • Elements for analysis of calcium
    • 钙分析要素
    • US4594225A
    • 1986-06-10
    • US775709
    • 1985-09-13
    • Kazumi AraiMikio KoyamaKenichiro Okaniwa
    • Kazumi AraiMikio KoyamaKenichiro Okaniwa
    • G01N33/84G01N21/78G01N31/00G01N31/22G01N33/52
    • G01N31/22
    • An improved multilayer analytical element for the determination of calcium comprising a liquid impermeable, optically transparent support; at least one reagent layer positioned with a first side on said support and containing at least one reagent capable of reacting with a calcium component in a fluid sample; and at least one porous developing layer on the second side of said reagent layer, said porous developing layer being permeable to calcium from said fluid sample thereby transporting said calcium to said reagent layer. The improvement comprises at least one of said reagent layer and developing layer containing a basic substance of the formula M.sub.v H.sub.w PO.sub.4 .multidot.ZH.sub.2 O wherein M is lithium, sodium or potassium; v is an integer of 2 or 3 and w is an integer of 0 or 1 provided that v plus w equals 3; and Z is 1/2 when M is lithium, 0, 2 or 12 when M is sodium and 0 or 8 when M is potassium; and said reagent layer contains (i) 3,3'-bis[N,N-di(carboxymethyl)aminomethyl]-o-cresolphthalein and (ii) 8-hydroxyquinoline or a derivative thereof.
    • 一种用于测定钙的改进的多层分析元件,其包含不透液体,光学透明的载体; 至少一个试剂层,其具有位于所述载体上的第一侧,并含有至少一种能够与流体样品中的钙组分反应的试剂; 以及在所述试剂层的第二侧上的至少一个多孔显影层,所述多孔显影层可从所述流体样品渗透钙,从而将所述钙输送到所述试剂层。 该改进包括至少一个所述试剂层和显影层,其含有式MvHwPO4xZH2O的碱性物质,其中M是锂,钠或钾; v是2或3的整数,w是0或1的整数,条件是v plus w等于3; 当M为锂时,Z为1/2,当M为钠时Z为0或2,当M为钾时为0或8; 并且所述试剂层含有(i)3,3'-双[N,N-二(羧甲基)氨基甲基] - 邻 - 甲酚酞和(ii)8-羟基喹啉或其衍生物。