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    • 61. 发明授权
    • Antibody that binds ceramidase
    • 结合神经酰胺酶的抗体
    • US07449553B2
    • 2008-11-11
    • US11783246
    • 2007-04-06
    • Makoto Ito
    • Makoto Ito
    • C07K16/00
    • C07K16/40C12N9/80C12Q1/34C12Y305/01023G01N33/573Y10S435/81
    • A neutral/alkaline ceramidase derived from a mammal; an antibody specifically binding thereto; a probe and primer which are capable of specifically hybridizing thereto; a method for producing the ceramidase by a genetic engineering means; a method for detecting the ceramidase or the gene; and a method of controlling an amount of a ceramide in a cell and/or in a tissue. The present invention is useful as a reagent for lipid engineering for analyzing a structure, functions, and the like of a ceramide, and in its applications to diseases associated with the ceramide metabolism.
    • 衍生自哺乳动物的中性/碱性神经酰胺酶; 与之结合的抗体; 能与其特异性杂交的探针和引物; 通过遗传工程方法制备神经酰胺酶的方法; 检测神经酰胺酶或基因的方法; 以及控制细胞和/或组织中神经酰胺量的方法。 本发明作为用于分析神经酰胺的结构,功能等的脂质体工程试剂及其与神经酰胺代谢相关的疾病的应用是有用的。
    • 64. 发明授权
    • High resistance silicon wafer and its manufacturing method
    • 高电阻硅晶片及其制造方法
    • US07397110B2
    • 2008-07-08
    • US10512405
    • 2003-04-16
    • Nobumitsu TakaseHideshi NishikawaMakoto ItoKoji SueokaShinsuke Sadamitsu
    • Nobumitsu TakaseHideshi NishikawaMakoto ItoKoji SueokaShinsuke Sadamitsu
    • H01L29/36H01L21/322
    • H01L21/3225
    • A high-resistance silicon wafer is manufactured in which a gettering ability, mechanical strength, and economical efficiency are excellent and an oxygen thermal donor is effectively prevented from being generated in a heat treatment for forming a circuit, which is implemented on the side of a device maker. A heat treatment for forming an oxygen precipitate nucleus is performed at 500 to 900° C. for 5 hours or more in a non-oxidizing atmosphere and a heat treatment for growing an oxygen precipitate is performed at 950 to 1050° C. for 10 hours or more on a high-oxygen and carbon-doped high-resistance silicon wafer in which resistivity is 100 Ωcm or more, an oxygen concentration is 14×1017 atoms/cm3 (ASTM F-121, 1979) or more and a carbon concentration is 0.5×1016 atoms/cm3 or more. By these heat treatments, a remaining oxygen concentration in the wafer is controlled to be 12×1017 atoms/cm3 (ASTM F-121, 1979) or less. Thus, there is provided a high-resistance, low-oxygen and high-strength silicon wafer in which resistivity is 100 Ωcm or more and an oxygen precipitate (BMD) having a size of 0.2 μm is formed so as to have high density of 1×104/cm2 or more.
    • 制造高电阻硅晶片,其中吸收能力,机械强度和经济效率优异,并且在用于形成电路的热处理中有效地防止了氧热供体的产生,该电路在 设备制造商。 在非氧化性气氛中,在500〜900℃下进行形成氧沉淀核的热处理5小时以上,在950〜1050℃下进行氧沉淀的热处理10小时 以上,电阻率为100Ωm以上的高氧和碳掺杂高电阻硅晶片,氧浓度为14×10 17原子/ cm 3(以下) ASTM F-121,1979)或更高,碳浓度为0.5×10 16原子/ cm 3以上。 通过这些热处理,将晶片中的剩余氧浓度控制为12×10 17原子/ cm 3(ASTM F-121,1979)或更小。 因此,提供了电阻率为100Ωm或更大的高电阻,低氧和高强度硅晶片,并且形成具有0.2μm大小的氧沉淀物(BMD),以便具有高密度的1×10 4/4以上。
    • 67. 发明授权
    • Color proofing method and apparatus, and recorded medium on which color proofing program is recorded
    • 彩色打样方法和装置以及记录了彩色打样程序的记录介质
    • US07321448B2
    • 2008-01-22
    • US11377149
    • 2006-03-16
    • Nobukatsu NishidaKazuyuki UragamiMakoto ItoNaoto Takeda
    • Nobukatsu NishidaKazuyuki UragamiMakoto ItoNaoto Takeda
    • H04N1/60H04N1/409G06K9/00G03F3/08
    • H04N1/6052B41M1/14G03F3/101H04N1/6033
    • In a method for improving the color reproducibility of printed matter to be produced by a printing press in proof print produced by a proof press, a look-up table containing converted values of image data over the entire color space with respect to the proof press is created, the look-up table is corrected based on the color of a printing paper for the printing press and a paper exposed area factor in the proofing, and proof print is created by the use of the corrected look-up table. Furthermore, proof printing image data, in which each of levels of monochromatic color gradation of black on the printed matter is represented on the proof print, out of the proof printing image data over the entire color space in a subtractive process resulting from color matching between proof print by the proof press and the printed matter by means of the printing press is corrected in such a manner that a part having a black ink area factor of 100% on the printed matter is represented only with black ink also on the proof print, but that a part other than the part having a black ink area factor of 100% on the printed matter is represented on the proof print by using under color removal, so that the representing characteristics of the black ink on the printed matter are reproduced on the proof print.
    • 在用于提高由印刷机在印刷机上产生的印刷品的色彩再现性的方法中,由校样印刷机产生的校样印刷品中,在整个颜色空间相对于证明印刷机的包含图像数据的转换值的查找表是 基于印刷机的打印纸的颜色和打样中的纸张曝光面积因子来校正查找表,并且通过使用校正的查找表来创建校样打印。 此外,在由打印物上的黑色的单色彩色等级的每个级别在校样印刷品上表示的校样打印图像数据中,从校正打印图像数据中的整个色彩空间中的校正打印图像数据中, 校正用印刷机和印刷品通过印刷机进行的防伪印刷的校正方法是使印刷品上的黑色墨水面积因子为100%的部分仅在印刷品上也用黑色墨水表示, 但是通过使用颜色去除,在打印物上的黑色油墨面积因子为100%的部分之外的部分被表示在证明打印件上,使得印刷品上的黑色墨水的表示特性在 打印证明。
    • 69. 发明申请
    • Optical information reader
    • 光信息阅读器
    • US20070045422A1
    • 2007-03-01
    • US11511223
    • 2006-08-29
    • Makoto Ito
    • Makoto Ito
    • G06K7/10
    • G06K7/10722
    • In an optical information reader, a case, and a light source is installed in the case. The light source supplies light. A lens is installed in the case and focuses the supplied light through part of the case onto optical information attached to a target. A particle blocking member is installed in the case to be arranged between the part of the case and the light source. The particle blocking member allows light reflected from the optical information to pass therethrough. The particle blocking member is integrally provided with a holder configured to support the light source. The particle blocking member blocks flow of particles into the light source side in the case.
    • 在光学信息阅读器中,壳体和光源安装在壳体中。 光源提供光源。 镜头安装在外壳中,并将提供的光通过外壳的一部分聚焦到连接到目标的光学信息上。 颗粒阻挡构件安装在壳体中以布置在壳体的一部分和光源之间。 粒子阻挡构件允许从光学信息反射的光通过。 颗粒阻挡构件一体地设置有支撑光源的支架。 在这种情况下,颗粒阻挡构件阻挡颗粒流入光源侧。