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61. 发明授权

US5842994A Multifunction intraluminal ultrasound catheter having a removable core with maximized transducer aperture 失效
标题翻译：多功能腔内超声导管具有最大化的换能器孔径的可移除的核心
公开(公告)号：US5842994A
公开(公告)日：1998-12-01
申请号：US886882
申请日：1997-07-02
申请人： Harm TenHoff , Isaac Ostrovsky , James D. Koger
发明人： Harm TenHoff , Isaac Ostrovsky , James D. Koger
IPC分类号： A61B8/12 , A61B8/00
CPC分类号： A61B8/12 , A61B8/445 , A61B8/4461
摘要： A multi-function intraluminal ultrasound catheter assembly includes an axially disposed lumen having at least a first portion with a flat inner wall forming a "D-shaped" cross-section. An acoustic imaging window having a circular cross-section is connected to a distal end of the catheter assembly, wherein the cross-sectional dimension of the D-shaped portion of the lumen that extends from the flat inner wall is less that the available inner diameter of the imaging window. A flexible drive-shaft extends through the lumen and is connected to a transducer housing disposed in the acoustic imaging window area, the transducer housing having a substantially "D-shaped" outer perimeter, wherein the drive-shaft and connected transducer housing may thereby be retracted from the catheter assembly by first rotating the transducer housing until its D-shaped outer perimeter is substantially oriented with the D-shaped cross-section of the lumen. In a preferred embodiment, the transducer housing also includes a longitudinally disposed transducer mounting section configured such that the active surface of a transducer mounted therein is generally aligned across the maximal inner diameter of the acoustic imaging window.
摘要翻译：多功能腔内超声导管组件包括轴向设置的腔，其具有至少第一部分，其具有形成“D”形横截面的平坦内壁。具有圆形横截面的声学成像窗口连接到导管组件的远端，其中从平坦内壁延伸的内腔的D形部分的横截面尺寸小于可用内径的成像窗口。灵活的驱动轴延伸穿过内腔并且连接到设置在声学成像窗口区域中的换能器壳体，换能器壳体具有基本上“D”形的外周边，其中驱动轴和连接的换能器壳体可以由此通过首先旋转换能器壳体直到其D形外周边基本上与内腔的D形横截面取向而从导管组件缩回。在优选实施例中，换能器壳体还包括纵向设置的换能器安装部分，其配置成使得安装在其中的换能器的主动表面大致对准在声学成像窗口的最大内径之间。

62. 发明授权

US08377051B2 Devices and methods for the treatment of endometriosis 有权
标题翻译：用于治疗子宫内膜异位症的装置和方法
公开(公告)号：US08377051B2
公开(公告)日：2013-02-19
申请号：US13014324
申请日：2011-01-26
申请人： Jon T. McIntyre , Francis P. Grillo , Isaac Ostrovsky
发明人： Jon T. McIntyre , Francis P. Grillo , Isaac Ostrovsky
IPC分类号： A61B18/04 , A61B8/00
CPC分类号： A61N7/00 , A61B1/00066 , A61B1/00087 , A61B1/00154 , A61B1/005 , A61B1/0638 , A61B1/0684 , A61B1/07 , A61B1/3132 , A61B90/30 , A61B2017/4216 , A61N5/0603 , A61N7/022
摘要： A tissue treatment device comprises an insertion section sized and shaped for insertion into the body via a trocar and a diagnostic element coupled to the insertion section, the diagnostic element illuminating tissue with light of a wavelength selected to facilitate identification of target tissue in combination with an ultrasound element coupled to the insertion section for delivering to a portion of tissue illuminated by the diagnostic element ultrasound energy.
摘要翻译：组织处理装置包括尺寸和形状适于通过套管针和连接到插入部分的诊断元件插入体内的插入部分，诊断元件用选择的波长的光照射组织以便于与耦合到插入部分的超声元件，用于输送到由诊断元件超声能量照射的组织的一部分。

63. 发明授权

US07991455B2 Systems and methods for dynamic optical imaging 有权
标题翻译：动态光学成像的系统和方法
公开(公告)号：US07991455B2
公开(公告)日：2011-08-02
申请号：US12103599
申请日：2008-04-15
申请人： Robert J. Crowley , Isaac Ostrovsky
发明人： Robert J. Crowley , Isaac Ostrovsky
IPC分类号： A61B6/00
CPC分类号： A61B5/6852 , A61B5/0066 , A61B5/02007
摘要： A medical system includes a catheter having an elongated tubular member and an inner core slideably received within the elongated member. The inner core includes an imager on a distal end and is coupled with a control system and an imaging system. The inner core is configured to scan the interior of a lumen by radially rotating around a center axis and axially translating along the center axis while within the elongated member. The medical system is configured to dynamically image a body lumen at a high speed in order to allow for optical imaging in a safe manner without long durations of blood sequestration and displacement. The medical system is configured to obtain three dimensional images of the body lumen with as little as one dimensional scanning of the lumen. Images of the lumen can be stored and viewed at a desired rate after scanning.
摘要翻译：医疗系统包括具有细长管状构件和可滑动地容纳在细长构件内的内芯的导管。内芯包括在远端上的成像器并与控制系统和成像系统耦合。内芯构造成通过围绕中心轴线径向旋转并沿着中心轴线在细长构件内沿轴向平移来扫描腔的内部。医疗系统被配置为以高速度动态地成像体腔，以便以安全的方式允许光学成像，而不需要长时间的血液吸收和移位。医疗系统被配置成通过对管腔的一维扫描获得体腔的三维图像。可以在扫描后以期望的速率存储和观看流明的图像。

64. 发明申请

US20110098701A1 BIPOLAR RADIO FREQUENCY ABLATION DEVICE WITH RETRACTABLE INSULATOR AND METHOD OF USING SAME 有权
标题翻译：具有可退回绝缘体的双极无线电频率消除装置及其使用方法
公开(公告)号：US20110098701A1
公开(公告)日：2011-04-28
申请号：US12878766
申请日：2010-09-09
申请人： Jon T. McIntyre , Isaac Ostrovsky
发明人： Jon T. McIntyre , Isaac Ostrovsky
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/00083 , A61B2018/00196 , A61B2018/00273 , A61B2018/00577 , A61B2018/143 , A61B2018/1432 , A61B2018/1435 , A61B2018/1467
摘要： An ablation device, comprises a first tubular element and a first electrode which, when in an insertion configuration, is received within the first tubular element, the first electrode being deployable from the first tubular element to anchor in a target portion of tissue at a first electrode operative position in combination with a second electrode which, when in the insertion configuration, is received within the first tubular element, the second electrode being deployable from the first tubular element to anchor in the target portion of tissue at a second electrode operative position separated from the first electrode operative position, the second electrode being deployable independently of the first electrode and an insulating element movable relative to the first electrode to insulate selected portions of the first electrode. A method of ablating tissue, comprises anchoring a first electrode at a first location in a target portion of tissue, deploying a second electrode at a second location in the target portion of tissue and applying current between the first and second electrodes to ablate a first ablation portion of tissue between the first and second electrodes in combination with moving an insulative cover relative to the first electrode to move a conductive portion of the first electrode to a third location within the target tissue, the third location being further from the second location than the first location, moving the second electrode to a fourth location within the target tissue, the fourth location being further from the first location than the second location and applying current between the conductive portion of the first electrode and the second electrode to ablate a second ablation portion of tissue surrounding the first ablation portion of tissue.
摘要翻译：消融装置包括第一管状元件和第一电极，当处于插入构型时，第一电极被容纳在第一管状元件内，第一电极可从第一管状元件展开，以在第一管状元件的第一电极操作位置与第二电极组合，当第二电极处于插入构型时，其被接收在第一管状元件内，第二电极可从第一管状元件展开，以在分开的第二电极操作位置锚定在组织的目标部分中从第一电极操作位置，第二电极可独立于第一电极展开，绝缘元件可相对于第一电极移动，以使第一电极的选定部分绝缘。一种消融组织的方法，包括将第一电极锚定在组织的目标部分中的第一位置处，在组织的目标部分中的第二位置处展开第二电极，并在第一和第二电极之间施加电流以消融第一消融组合在第一和第二电极之间的部分结合使绝缘盖相对于第一电极移动，以将第一电极的导电部分移动到目标组织内的第三位置，第三位置比第二位置更远第一位置，将第二电极移动到目标组织内的第四位置，第四位置比第二位置更远离第一位置，并且在第一电极的导电部分和第二电极之间施加电流以烧蚀第二消融部分围绕组织的第一消融部分的组织。

65. 发明授权

US07837682B2 Device and method for positioning of a therapeutic device 失效
标题翻译：用于定位治疗装置的装置和方法
公开(公告)号：US07837682B2
公开(公告)日：2010-11-23
申请号：US11397519
申请日：2006-04-04
申请人： Isaac Ostrovsky , Ty Fairneny , Victor Shukhat , Alfred Intoccia , Jon T. McIntyre
发明人： Isaac Ostrovsky , Ty Fairneny , Victor Shukhat , Alfred Intoccia , Jon T. McIntyre
IPC分类号： A61B18/18 , A61B18/14
CPC分类号： A61B90/39 , A61B2017/00805 , A61B2034/2051 , A61B2090/3929 , A61F2/005 , A61F2250/0001
摘要： A system comprises a first signal handling unit sized and shaped for insertion to a reference distance within a first body cavity and a probe sized and shaped for insertion into a second body cavity the probe including an energy emitting head and a second signal handling unit, wherein one of the first and second signal handling units comprises a transmitter and the other of the first and second signal handling units comprises one of a receiver adapted to receive signals from the transmitter and a signal reflecting element, wherein, when the other of the first and second signal handling units comprises a signal reflecting element, the one of the first and second signal handling units comprises a receiver in combination with a controller operatively connected to the receiver, the controller generating an output varying as a distance between the first and second signal handling units varies. In addition, a system comprises a probe sized and shaped for insertion in a first body cavity and a measuring element extending from the probe to contact tissue adjacent to an opening to a second body cavity, the measuring element being movably coupled to the probe to vary a depth to which the probe may be inserted into the first body cavity before the measuring element contacts the tissue adjacent to the opening of the second body cavity.
摘要翻译：一种系统包括第一信号处理单元，其尺寸和形状适于插入第一体腔内的参考距离;以及尺寸和形状适于插入第二体腔的探针，所述探针包括能量发射头和第二信号处理单元，其中第一信号处理单元和第二信号处理单元之一包括发送器，第一和第二信号处理单元中的另一个包括适于从发送器接收信号的接收器和信号反射元件中的一个，其中，当第一和第二信号处理单元第二信号处理单元包括信号反射元件，第一和第二信号处理单元之一包括与可操作地连接到接收器的控制器组合的接收器，所述控制器产生以第一和第二信号处理之间的距离变化的输出单位不一。此外，系统包括尺寸和形状适于插入第一体腔中的探针和从探针延伸到与第二体腔的开口相邻的接触组织的测量元件，测量元件可移动地联接到探针以变化在测量元件接触与第二体腔的开口相邻的组织之前，探针可以插入到第一体腔中的深度。

66. 发明授权

US07797035B2 Medical scanning system and related method of scanning 有权
标题翻译：医疗扫描系统及相关扫描方法
公开(公告)号：US07797035B2
公开(公告)日：2010-09-14
申请号：US11032228
申请日：2005-01-11
申请人： Isaac Ostrovsky
发明人： Isaac Ostrovsky
IPC分类号： A61B6/00 , G02B26/08 , G02B26/10 , G02B26/12
CPC分类号： A61B5/6852 , A61B1/0008 , A61B1/00096 , A61B1/00172 , A61B5/0062 , A61B5/0066 , A61B5/0084 , G01N21/4795
摘要： The present invention is directed to a scanning system that uses uniform rotary motion of an optical reflector to create reciprocal linear scanning. The system converts uniform rotation into uniform longitudinal scanning. The system thereby creates mechanical reciprocal linear scanning free of reciprocally moving mechanical parts common in conventional scanning systems. In a preferred embodiment of the invention, the scanning system is incorporated within an imaging catheter for medical scanning. The optical reflector is rotatable and includes a spiral reflecting portion. The spiral reflecting portion may be a single uniform reflecting surface or may include several reflection surfaces arranged in a spiral configuration.
摘要翻译：本发明涉及一种使用光学反射器的均匀旋转运动来产生相互线性扫描的扫描系统。系统将均匀旋转转换为均匀的纵向扫描。因此，该系统产生机械的往复线性扫描，不存在常规扫描系统中常见的往复运动的机械部件。在本发明的优选实施例中，扫描系统被结合在用于医学扫描的成像导管内。光反射器是可旋转的并且包括螺旋反射部分。螺旋反射部分可以是单个均匀的反射表面，或者可以包括以螺旋构造布置的多个反射表面。

67. 发明申请

US20090160112A1 STRUCTURE FOR USE AS PART OF A MEDICAL DEVICE 有权
标题翻译：结构作为医疗器械的一部分使用
公开(公告)号：US20090160112A1
公开(公告)日：2009-06-25
申请号：US12336845
申请日：2008-12-17
申请人： Isaac Ostrovsky
发明人： Isaac Ostrovsky
IPC分类号： F16F1/06 , B23P11/00
CPC分类号： A61M25/0013 , A61B1/0055 , A61M25/0043 , A61M25/0054 , A61M2025/09066
摘要： A low cost, flexible, torqueable structure for use as at least a portion of a medical device comprises a coil formed of a wound element. The coil includes a plurality of adjacent windings. Connected portions of a region between the adjacent windings are formed (by, for example, laser welding) such that torque can be transmitted between adjacent windings.
摘要翻译：用作医疗装置的至少一部分的低成本，柔性，可扭转的结构包括由伤口元件形成的线圈。线圈包括多个相邻绕组。形成相邻绕组之间的区域的连接部分（例如通过激光焊接），使得可以在相邻绕组之间传递转矩。

68. 发明授权

US07517346B2 Radio frequency ablation system with integrated ultrasound imaging 有权
标题翻译：射频消融系统与集成超声成像
公开(公告)号：US07517346B2
公开(公告)日：2009-04-14
申请号：US11053344
申请日：2005-02-08
申请人： Todd Sloan , Isaac Ostrovsky , Jon T. McIntyre
发明人： Todd Sloan , Isaac Ostrovsky , Jon T. McIntyre
IPC分类号： A61B18/14 , A61B8/12
CPC分类号： A61B18/1477 , A61B2018/143 , A61B2018/1432 , A61B2090/378 , A61B2090/3782
摘要： A tissue ablation system comprises a first electrode assembly adapted for insertion into a target tissue mass within a body, the first electrode assembly including a first electrode coupled to a source of RF energy in combination with an ultrasound imaging probe movably coupled to the first electrode assembly for insertion with the first electrode assembly to a desired location relative to the target tissue mass, the probe being movable relative to the first electrode assembly between an insertion configuration in which a distal end of the probe covers a distal end of the first electrode assembly and a deployed configuration in which the distal end of the first electrode assembly is uncovered. A method of ablating target tissue within a body comprises placing a distal dome of an ultrasound imaging probe in overlying alignment with a first cannula of an RF ablation device and inserting the probe and the RF ablation device through a lumen of an insertion device to a desired location adjacent to a target tissue mass in combination with moving the distal dome away from a distal end of the first cannula to expose a distal end thereof, inserting the distal end of the first cannula into the target tissue mass to position a first electrode of the RF ablation device at a first desired location within the target tissue mass, obtaining an image of the target tissue mass and the first electrode via the probe and applying RF energy to the target tissue mass via the first electrode.
摘要翻译：组织消融系统包括适于插入到体内的靶组织块中的第一电极组件，所述第一电极组件包括耦合到RF能量源的第一电极与可移动地联接到第一电极组件的超声成像探头组合为了将第一电极组件相对于目标组织块插入到期望的位置，探针可相对于第一电极组件在插入构造之间移动，其中探针的远端覆盖第一电极组件的远端和展开构造，其中第一电极组件的远端未被覆盖。消除体内靶组织的方法包括将超声成像探针的远侧圆顶放置在与RF消融装置的第一插管对齐的位置上，并将探针和RF消融装置插入穿过插入装置的内腔至期望的将目标组织块的位置与移动远端圆顶远离第一插管的远端结合以暴露其远端的位置，将第一插管的远端插入目标组织块中以将第一电极 RF消融装置，其经由所述探针获得所述目标组织质量和所述第一电极的图像，并且经由所述第一电极向所述目标组织块施加RF能量。

69. 发明授权

US07376455B2 Systems and methods for dynamic optical imaging 有权
标题翻译：动态光学成像的系统和方法
公开(公告)号：US07376455B2
公开(公告)日：2008-05-20
申请号：US10444171
申请日：2003-05-22
申请人： Robert J. Crowley , Isaac Ostrovsky
发明人： Robert J. Crowley , Isaac Ostrovsky
IPC分类号： A61B6/00
CPC分类号： A61B5/6852 , A61B5/0066 , A61B5/02007
摘要： A medical system includes a catheter having an elongated tubular member and an inner core slideably received within the elongated member. The inner core includes an imager on a distal end and is coupled with a control system and an imaging system. The inner core is configured to scan the interior of a lumen by radially rotating around a center axis and axially translating along the center axis while within the elongated member. The medical system is configured to dynamically image a body lumen at a high speed in order to allow for optical imaging in a safe manner without long durations of blood sequestration and displacement. The medical system is configured to obtain three dimensional images of the body lumen with as little as one dimensional scanning of the lumen. Images of the lumen can be stored and viewed at a desired rate after scanning.
摘要翻译：医疗系统包括具有细长管状构件和可滑动地容纳在细长构件内的内芯的导管。内芯包括在远端上的成像器并与控制系统和成像系统耦合。内芯构造成通过围绕中心轴线径向旋转并沿着中心轴线在细长构件内沿轴向平移来扫描腔的内部。医疗系统被配置为以高速度动态地成像体腔，以便以安全的方式允许光学成像，而不需要长时间的血液吸收和移位。医疗系统被配置成通过对管腔的一维扫描获得体腔的三维图像。可以在扫描后以期望的速率存储和观看流明的图像。

70. 发明申请

US20070219602A1 Device for thermal treatment of tissue and for temperature measurement of tissue providing feedback 有权
标题翻译：用于组织热处理和用于提供反馈的组织的温度测量的装置
公开(公告)号：US20070219602A1
公开(公告)日：2007-09-20
申请号：US11374811
申请日：2006-03-14
申请人： Isaac Ostrovsky , Victor Shukhat , Alfred Intoccia , Jon McIntyre , Ty Fairneny
发明人： Isaac Ostrovsky , Victor Shukhat , Alfred Intoccia , Jon McIntyre , Ty Fairneny
IPC分类号： A61F7/00 , A61B18/04 , A61F7/12
CPC分类号： A61N7/022 , A61B2017/00084 , A61B2090/378 , A61N2007/0078
摘要： A device for heating tissue, comprises a housing sized for insertion through a naturally occurring body orifice to a target location within a lumen and a heat generating element within the housing focusing thermal energy on a target area separated from an outside of the housing so that, when the housing is in the target location, the target area is within tissue surrounding the lumen at a predetermined depth from a lumenal wall in combination with a temperature sensing element sensing data corresponding to a temperature of tissue in the target area and a processor controlling the heat generating element in response to the data sensed by the sensing element.
摘要翻译：一种用于加热组织的装置，包括尺寸适于通过天然存在的身体孔口插入管腔内的目标位置的壳体和壳体内的发热元件，将热能聚焦在与壳体的外部分离的目标区域上，当外壳处于目标位置时，目标区域在与腔壁预定深度相对的管腔周围的组织内，结合温度感测元件感测对应于目标区域中的组织温度的数据，以及控制对象区域的处理器发热元件响应于由感测元件感测的数据。

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