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61. 发明申请

US20080132930A1 Tissue cutting member for a biopsy device 有权
标题翻译：用于活检装置的组织切割构件
公开(公告)号：US20080132930A1
公开(公告)日：2008-06-05
申请号：US11981292
申请日：2007-10-31
申请人： Paul Lubock , Frank R. Louw , Richard L. Quick
发明人： Paul Lubock , Frank R. Louw , Richard L. Quick
IPC分类号： A61B17/32
CPC分类号： A61B10/0275 , A61B10/0283 , A61B17/320016 , A61B17/3417
摘要： The invention is directed to tissue cutting members and biopsy devices with such tissue cutting member for separating a tissue specimen from a patient's body at a target site. The tissue cutting member is slidably disposed within an inner lumen of an elongated probe member of the biopsy device to cut a tissue specimen drawn into the interior of an outer cannula of the biopsy device through a tissue receiving aperture in the probe. The tissue cutting member has a tubular distal portion with a distal tip having an outer tissue cutting edge, an inner tissue receiving aperture, and a longitudinally oriented opening with a closed proximal end and open distal end which opens to the inner tissue receiving aperture to facilitate flaring of the distal tubular portion. The cutting member has at least one opening in a wall of the tubular portion to maintain a vacuum during use.
摘要翻译：本发明涉及具有这种组织切割构件的组织切割构件和活检装置，用于在目标部位处将组织标本与患者的身体分离。组织切割构件可滑动地设置在活检装置的细长探针构件的内腔中，以通过探针中的组织接收孔切割拉入活检装置的外套管内部的组织样本。组织切割构件具有管状远端部分，远侧末端具有外部组织切割边缘，内部组织接收孔和纵向定向的开口，其具有封闭的近端和敞开的远端，其通向内部组织接收孔以便于远端管状部分的扩口。切割构件在管状部分的壁中具有至少一个开口，以在使用期间保持真空。

62. 发明申请

US20080125644A1 MRI imageable assembly 审中-公开
标题翻译： MRI可成像组装
公开(公告)号：US20080125644A1
公开(公告)日：2008-05-29
申请号：US11978782
申请日：2007-10-30
申请人： Paul Lubock , Richard L. Quick , Ethan Broadaway
发明人： Paul Lubock , Richard L. Quick , Ethan Broadaway
IPC分类号： A61B5/055
CPC分类号： A61B17/3468 , A61B5/055 , A61B17/3498 , A61B90/39 , A61B2017/00477 , A61B2090/062 , A61B2090/3908 , A61B2090/3954 , A61B2090/3987
摘要： A marker delivery device is described which has an obturator with an elongated shaft, an inner lumen, a proximal end, and a substantially sealed distal end. One or more tissue markers are deployed within the inner lumen of the elongated shaft of the obturator. Preferably, the tissue marker(s) is disposed within an inner lumen of a marker delivery tube which is disposed within the inner lumen of the elongated shaft of the obturator. The marker delivery tube has an opening for discharging the tissue markers into a body (e.g. biopsy) cavity. The distal tip of the marker delivery tube is configured to penetrate the substantially sealed distal end of the obturator so that tissue markers can be delivered while the obturator is in place within the body. Preferably, the obturator includes a detectable element capable of producing a relatively significant image signature during MRI.
摘要翻译：描述了一种标记输送装置，其具有带有细长轴，内腔，近端和基本上密封的远端的闭塞器。一个或多个组织标记部署在闭塞器的细长轴的内腔内。优选地，组织标记设置在标记输送管的内腔内，该标记物输送管设置在闭塞器的细长轴的内腔内。标记物输送管具有用于将组织标记物排放到体内（例如活检）腔的开口。标记物输送管的远侧末端构造成穿透闭塞器的基本上密封的远端，使得组织标记物可以在闭塞器在体内就位的同时被输送。优选地，闭孔器包括能够在MRI期间产生相对显着的图像特征的可检测元件。

63. 发明授权

US07282034B2 Tissue accessing and anchoring device and method 有权
标题翻译：组织进入和锚定装置和方法
公开(公告)号：US07282034B2
公开(公告)日：2007-10-16
申请号：US10729086
申请日：2003-12-05
申请人： Fred H. Burbank , Paul Lubock , John Wardle , Frank Louw , Richard L. Quick
发明人： Fred H. Burbank , Paul Lubock , John Wardle , Frank Louw , Richard L. Quick
IPC分类号： A61B10/00
CPC分类号： A61B10/0266 , A61B6/4258 , A61B10/02 , A61B17/00491 , A61B18/1477 , A61B18/148 , A61B18/1482 , A61B18/1487 , A61B18/1815 , A61B90/39 , A61B2010/0208 , A61B2017/00115 , A61B2017/00867 , A61B2017/3488 , A61B2018/00208 , A61B2018/00273 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00916 , A61B2018/00958 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3904 , A61B2090/3908 , A61B2090/392
摘要： The invention provides systems, methods and a node accessing and anchoring device, comprising an elongated shaft, a tissue cutting member, at least one anchoring element extending from a position at or near the distal end of the shaft; and a radiation detector. The radiation detector is effective to locate and identify sentinel lymph nodes following injection of radioactive material into a primary lesion site within a patient. The tissue cutting member, which may be activated with radio frequency energy, is effective to allow access of the elongated shaft to a sentinel lymph node. The anchoring elements are effective to anchor the device to or adjacent a sentinel lymph node accessed by the device. Anchoring elements may assume radially, longitudinally, or mixed radially and longitudinally curved or coiled configurations when deployed.
摘要翻译：本发明提供系统，方法和节点访问和锚定装置，包括细长轴，组织切割构件，至少一个锚固元件，其从所述轴的远端处或附近的位置延伸; 和辐射探测器。放射线检测器在将放射性物质注入患者的原发性病变部位之后，有效地定位和识别前哨淋巴结。可以用射频能量激活的组织切割构件有效地允许细长轴进入前哨淋巴结。锚定元件有效地将装置锚定到或邻近由装置访问的前哨淋巴结。锚定元件在展开时可以呈径向，纵向或混合的径向和纵向弯曲或卷绕构型。

64. 发明授权

US07261712B2 Electrosurgical lesion location device 有权
标题翻译：电外科病变位置装置
公开(公告)号：US07261712B2
公开(公告)日：2007-08-28
申请号：US09967755
申请日：2001-09-28
申请人： Fred H. Burbank , Frank R. Louw , Paul Lubock , Richard L. Quick
发明人： Fred H. Burbank , Frank R. Louw , Paul Lubock , Richard L. Quick
IPC分类号： A61B18/18
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A device for localizing a target tissue mass in a body includes a tubular trocar portion having a distal end and a proximal end portion that is removably attachable to a handle portion. The trocar portion contains at least a first plurality of locator wires that are movable between a retracted position within the trocar and a deployed position extending radially from the trocar. In a preferred embodiment, the trocar portion has an electrosurgical cutting element at its distal end, and first and second pluralities of locator wires that, when deployed, respectively define first and second locating perimeters.
摘要翻译：用于使身体中的目标组织块定位的装置包括管状套管针部分，其具有可拆卸地附接到手柄部分的远端和近端部分。套针针部分包含至少第一组多个定位线，其可在套管针内的缩回位置和从套管针径向延伸的展开位置之间移动。在优选实施例中，套管针部分在其远端具有电外科切割元件，以及当展开时分别限定第一和第二定位周边的第一和第二多个定位线。

65. 发明授权

US06997885B2 Dilation devices and methods for removing tissue specimens 有权
公开(公告)号：US06997885B2
公开(公告)日：2006-02-14
申请号：US09916937
申请日：2001-07-27
申请人： Paul Lubock , Richard L. Quick
发明人： Paul Lubock , Richard L. Quick
IPC分类号： A61B10/00
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/0218 , A61B17/282 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B17/3439 , A61B18/14 , A61B18/1477 , A61B18/148 , A61B18/1482 , A61B18/1487 , A61B18/1492 , A61B90/02 , A61B90/37 , A61B90/39 , A61B2010/0208 , A61B2017/320064 , A61B2017/320733 , A61B2017/3484 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2018/1861 , A61B2090/3908
摘要： The invention provides devices and methods for use in removing tissue samples from within a patient's body. The devices include instruments having shafts for cutting a path to a tissue mass, and an inflatable balloon or balloons attached to the shaft effective to dilate the path upon inflation in order to aid in the removal of tissue masses from within the body of a patient. The devices also include instruments having dilation plates that may be inserted into a path leading to a tissue mass to be removed, and the plates separated effective to dilate the path to aid in the removal of tissue masses. Methods include inserting a device into a path leading to a tissue mass, and inflating a balloon or separating plates, thereby widening the path, and removing the tissue mass. Such devices and methods find use, for example, in biopsy and in lumpectomy procedures.

66. 发明授权

US06679851B2 Tissue accessing and anchoring device and method 有权
公开(公告)号：US06679851B2
公开(公告)日：2004-01-20
申请号：US09880218
申请日：2001-06-12
申请人： Fred H. Burbank , Paul Lubock , John Wardle , Frank Louw , Richard L. Quick
发明人： Fred H. Burbank , Paul Lubock , John Wardle , Frank Louw , Richard L. Quick
IPC分类号： A61B1000
CPC分类号： A61B10/0266 , A61B6/4258 , A61B10/02 , A61B17/00491 , A61B18/1477 , A61B18/148 , A61B18/1482 , A61B18/1487 , A61B18/1815 , A61B90/39 , A61B2010/0208 , A61B2017/00115 , A61B2017/00867 , A61B2017/3488 , A61B2018/00208 , A61B2018/00273 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00916 , A61B2018/00958 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3904 , A61B2090/3908 , A61B2090/392
摘要： The invention provides systems, methods and a node accessing and anchoring device, comprising an elongated shaft, a tissue cutting member, at least one anchoring element extending from a position at or near the distal end of the shaft; and a radiation detector. The radiation detector is effective to locate and identify sentinel lymph nodes following injection of radioactive material into a primary lesion site within a patient. The tissue cutting member, which may be activated with radio frequency energy, is effective to allow access of the elongated shaft to a sentinel lymph node. The anchoring elements are effective to anchor the device to or adjacent a sentinel lymph node accessed by the device. Anchoring elements may assume radially, longitudinally, or mixed radially and longitudinally curved or coiled configurations when deployed.

67. 发明授权

US06620157B1 High frequency power source 有权
标题翻译：高频电源
公开(公告)号：US06620157B1
公开(公告)日：2003-09-16
申请号：US09752978
申请日：2000-12-28
申请人： James Huntington Dabney , Richard L. Quick , Conrad Sawicz , Paul Lubock , Dan Kussman
发明人： James Huntington Dabney , Richard L. Quick , Conrad Sawicz , Paul Lubock , Dan Kussman
IPC分类号： A61B1818
CPC分类号： G01R31/025 , A61B18/042 , A61B18/1206 , A61B18/16 , A61B18/18 , A61B34/35 , A61B2018/00601 , A61B2018/00607 , A61B2018/00666 , A61B2018/00702 , A61B2018/00726 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/00898 , A61B2018/0094 , A61B2018/1213 , A61B2018/1266 , A61B2018/1286 , A61B2018/162
摘要： A high frequency electrosurgical power generator configured to produce electrical power at a frequency of about 1 to about 14 MHz and preferably having an essentially sinusoidal waveform with a voltage level up to 1,000 Vrms, and a current level up to 5 Amps. The output of the high frequency electrosurgical power generator is connected to an electrosurgical tool configured to receive the voltage and current produced by the electrosurgical power generator and deliver the voltage and current to an electrosurgical site. The output of the electrosurgical generator preferably is an essentially sinusoid waveform with a frequency between about 3 MHz and about 8 MHz, up to about 700 volts rms, up to about 2 amps, with a total power of up to 1,000 watts.
摘要翻译：一种高频电外科发电机，其配置成以约1至约14MHz的频率产生电力，并且优选地具有基本上正弦波形，其电压电平高达1000Vrms，电流水平高达5安培。高频电外科发电机的输出连接到电外科手术工具，其被配置为接收由电外科发电机产生的电压和电流，并将电压和电流传递到电外科手术部位。电外科发生器的输出优选地是基本上是正弦波形，其频率在约3MHz至约8MHz之间，高达约700V rms，高达约2安培，总功率高达1,000瓦。

68. 发明授权

US09750557B2 High frequency power source 有权
公开(公告)号：US09750557B2
公开(公告)日：2017-09-05
申请号：US11703861
申请日：2007-02-08
申请人： James Huntington Dabney , Richard L. Quick , Conrad Sawicz , Paul Lubock , Dan Kussman
发明人： James Huntington Dabney , Richard L. Quick , Conrad Sawicz , Paul Lubock , Dan Kussman
IPC分类号： A61B18/12 , A61B18/18 , A61B18/00
CPC分类号： G01R31/025 , A61B18/042 , A61B18/1206 , A61B18/16 , A61B18/18 , A61B34/35 , A61B2018/00601 , A61B2018/00607 , A61B2018/00666 , A61B2018/00702 , A61B2018/00726 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/00898 , A61B2018/0094 , A61B2018/1213 , A61B2018/1266 , A61B2018/1286 , A61B2018/162
摘要： A high frequency electrosurgical power generator configured to produce electrical power at a frequency of about 1 to about 14 MHz and preferably having an essentially sinusoidal waveform with a voltage level up to 1,000 Vrms, and a current level up to 5 Amps. The output of the high frequency electrosurgical power generator is connected to an electrosurgical tool configured to receive the voltage and current produced by the electrosurgical power generator and deliver the voltage and current to an electrosurgical site. The output of the electrosurgical generator preferably is an essentially sinusoid waveform with a frequency between about 3 MHz and about 8 MHz, up to about 700 volts rms, up to about 2 amps, with a total power of up to 1,000 watts.

69. 发明授权

US08764741B2 High frequency power source 有权
标题翻译：高频电源
公开(公告)号：US08764741B2
公开(公告)日：2014-07-01
申请号：US11890945
申请日：2007-08-08
申请人： James Huntington Dabney , Richard L. Quick , Conrad Sawicz , Paul Lubock , Dan Kussman
发明人： James Huntington Dabney , Richard L. Quick , Conrad Sawicz , Paul Lubock , Dan Kussman
IPC分类号： A61B18/12 , A61B18/00
CPC分类号： G01R31/025 , A61B18/042 , A61B18/1206 , A61B18/16 , A61B18/18 , A61B34/35 , A61B2018/00601 , A61B2018/00607 , A61B2018/00666 , A61B2018/00702 , A61B2018/00726 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/00898 , A61B2018/0094 , A61B2018/1213 , A61B2018/1266 , A61B2018/1286 , A61B2018/162
摘要： A high frequency electrosurgical power generator configured to produce electrical power at a frequency of about 1 to about 14 MHz and preferably having an essentially sinusoidal waveform with a voltage level up to 1,000 Vrms, and a current level up to 5 Amps. The output of the high frequency electrosurgical power generator is connected to an electrosurgical tool configured to receive the voltage and current produced by the electrosurgical power generator and deliver the voltage and current to an electrosurgical site. The output of the electrosurgical generator preferably is an essentially sinusoid waveform with a frequency between about 3 MHz and about 8 MHz, up to about 700 volts rms, up to about 2 amps, with a total power of up to 1,000 watts.
摘要翻译：一种高频电外科发电机，其配置成以约1至约14MHz的频率产生电力，并且优选地具有基本上正弦波形，其电压电平高达1000Vrms，电流水平高达5安培。高频电外科发电机的输出连接到电外科手术工具，其被配置为接收由电外科发电机产生的电压和电流，并将电压和电流传递到电外科手术部位。电外科发生器的输出优选地是基本上是正弦波形，其频率在约3MHz至约8MHz之间，高达约700V rms，高达约2安培，总功率高达1,000瓦。

70. 发明申请

US20100010342A1 Tissue site markers for in vivo imaging 有权
标题翻译：用于体内成像的组织位点标记
公开(公告)号：US20100010342A1
公开(公告)日：2010-01-14
申请号：US12460052
申请日：2009-07-13
申请人： Fred H. Burbank , Paul Lubock , Micheal L. Jones , Richard L. Quick , Frank Louw , Stephen A. De Santis
发明人： Fred H. Burbank , Paul Lubock , Micheal L. Jones , Richard L. Quick , Frank Louw , Stephen A. De Santis
IPC分类号： A61B8/14
CPC分类号： A61M37/0069 , A61B6/12 , A61B8/0833 , A61B10/02 , A61B90/39 , A61B2017/00004 , A61B2090/08021 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61K49/006 , A61K49/222
摘要： The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging. The biopsy site marker may be accurately fixed to the biopsy site so as to resist migration from the biopsy cavity when a placement instrument is withdrawn, and when the marked tissue is subsequently moved or manipulated.
摘要翻译：本发明涉及活检部位标记和标记活组织检查部位的方法，使得活检腔的位置通过常规成像方法，特别是通过超声成像容易看到。本发明的活检部位标记物具有高的超声反射率，从小标记物呈现出实质的声学特征，以避免在随后的成像研究中掩盖诊断组织特征，并且可以容易地与生物特征区别开来。本发明的活检部位标记物的几个公开的实施方案具有放置在组织部位中的声阻抗的高对比度，以便有效地反射和散射超声能量，并且优选地包括气体填充的内部孔。标记可以具有不均匀的表面轮廓以增强声学特征。标记具有在医学成像期间可识别人造的特征形式。可以将活检部位标记物精确地固定到活检部位，以便当放置放置器械被取出时以及随后移动或操纵标记的组织时抵抗活组织腔的迁移。

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