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61. 发明授权

US08992515B2 Coolant injection tube 有权
标题翻译：冷却液注射管
公开(公告)号：US08992515B2
公开(公告)日：2015-03-31
申请号：US12269493
申请日：2008-11-12
申请人： Jean-Pierre Lalonde , Marwan Abboud , Teresa Ann Mihalik , Jean-Pierre Desmarais , Dan Wittenberger
发明人： Jean-Pierre Lalonde , Marwan Abboud , Teresa Ann Mihalik , Jean-Pierre Desmarais , Dan Wittenberger
IPC分类号： A61B18/18 , A61B18/02 , A61B17/22 , A61B18/00
CPC分类号： A61B18/02 , A61B2017/00318 , A61B2017/22038 , A61B2017/22051 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262
摘要： A medical device includes a steering element defining a passage for a guide wire. A fluid injection tube defining a proximal and a distal end is also included, wherein a portion of the fluid injection tube is contoured about a portion of the steering element. A plurality of injection ports may be disposed in the portion of the fluid injection tube contoured about the steering element.
摘要翻译：医疗装置包括限定用于导丝的通道的操纵元件。还包括限定近端和远端的流体注入管，其中流体注入管的一部分围绕转向元件的一部分成形。多个注射口可以设置在围绕转向元件成形的流体注射管的部分中。

62. 发明授权

US08679105B2 Device and method for pulmonary vein isolation 有权
标题翻译：肺静脉隔离装置及方法
公开(公告)号：US08679105B2
公开(公告)日：2014-03-25
申请号：US12845312
申请日：2010-07-28
申请人： Dan Wittenberger , Ioana Alina Deac , Jean-Pierre Lalonde , Deborah A. De Roy
发明人： Dan Wittenberger , Ioana Alina Deac , Jean-Pierre Lalonde , Deborah A. De Roy
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B18/1492 , A61B2018/00255 , A61B2018/00285 , A61B2018/00375 , A61B2018/00577 , A61B2018/00994 , A61B2018/0212 , A61B2018/0262
摘要： An intravascular catheter is provided, including a flexible elongate body; an expandable element positioned on the elongate body; a substantially linear thermal segment located distally of the expandable element; a first fluid flow path in fluid communication with the expandable element; and a second fluid flow path in fluid communication with the substantially linear thermal segment.
摘要翻译：提供血管内导管，包括柔性细长体; 定位在细长体上的可扩张元件; 位于所述可扩张元件的远端的基本线性的热段; 与可膨胀元件流体连通的第一流体流动路径; 以及与所述基本上线性的热段流体连通的第二流体流动路径。

63. 发明授权

US08672930B2 Endoluminal ablation cryoballoon and method 有权
标题翻译：腔内消融低温和方法
公开(公告)号：US08672930B2
公开(公告)日：2014-03-18
申请号：US12845492
申请日：2010-07-28
申请人： Dan Wittenberger
发明人： Dan Wittenberger
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2018/00255 , A61B2018/00642 , A61B2018/00714 , A61B2018/00744 , A61B2018/00791 , A61B2018/00863 , A61B2018/0212 , A61B2090/064
摘要： A method of ablating tissue is provided, including positioning an expandable element of a catheter in a blood vessel; inflating the expandable element with a volume of refrigerant to substantially occlude the blood vessel; measuring the volume of refrigerant used to inflate the expandable element; correlating the measured volume to an inflated dimension of the expandable element; defining at least one of a target pressure within the expandable element and a target flow rate for refrigerant delivery to the expandable element based at least in part on the inflated dimension; regulating refrigerant delivery to the expandable element to attain the at least one defined target pressure within the expandable element or defined target flow rate for fluid delivery to the expandable element; and ablating at least a portion of the blood vessel with the expandable element.
摘要翻译：提供一种消融组织的方法，包括将导管的可扩张元件定位在血管中; 用一定体积的制冷剂使可膨胀元件充气以基本上封闭血管; 测量用于使可膨胀元件膨胀的制冷剂的体积; 将测量的体积与可膨胀元件的膨胀尺寸相关联; 至少部分地基于所述膨胀的尺寸限定所述可膨胀元件内的目标压力中的至少一个和用于制冷剂输送到所述可膨胀元件的目标流量; 调节向所述可膨胀元件的制冷剂输送以达到所述可膨胀元件内的所述至少一个限定的目标压力或用于流体输送到所述可膨胀元件的限定的目标流速; 以及用所述可扩张元件烧蚀所述血管的至少一部分。

64. 发明授权

US07914526B2 Cryosurgical catheter 有权
标题翻译：冷冻导管
公开(公告)号：US07914526B2
公开(公告)日：2011-03-29
申请号：US12791985
申请日：2010-06-02
申请人： John W. Lehmann , Dan Wittenberger , Claudia Luckge , Jean-Pierre Lalonde , Cristian Petre , Domenic Santoianni
发明人： John W. Lehmann , Dan Wittenberger , Claudia Luckge , Jean-Pierre Lalonde , Cristian Petre , Domenic Santoianni
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/00243 , A61B2017/00292 , A61B2017/00973 , A61B2018/00095 , A61B2018/0212 , A61F2007/0298 , A61M25/0029 , A61M2025/0039 , Y10S977/906
摘要： A cryogenic catheter includes an outer flexible member having at least one cryogenic fluid path through the flexible member. The at least one fluid path is defined by a plurality of flexible members disposed within the outer flexible member.
摘要翻译：低温导管包括具有穿过柔性构件的至少一个低温流体路径的外部柔性构件。至少一个流体路径由设置在外部柔性构件内的多个柔性构件限定。

65. 发明授权

US07780657B2 Cooling system 有权
标题翻译：冷却系统
公开(公告)号：US07780657B2
公开(公告)日：2010-08-24
申请号：US11709964
申请日：2007-02-23
申请人： Marwan Abboud , Rachid Mahrouche , Jean-Pierre Lalonde , Dan Wittenberger
发明人： Marwan Abboud , Rachid Mahrouche , Jean-Pierre Lalonde , Dan Wittenberger
IPC分类号： A61B18/18
CPC分类号： A61B18/02 , A61B2017/00084 , A61B2017/00199 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268
摘要： A cryogenic medical system includes a medical device and a console connectable to the medical device at a connection point. The console controls the temperature of the medical device. The console includes a first cooling system directing coolant to the medical device at a first temperature along a coolant supply line and a second cooling system chilling the coolant within the coolant supply line to a temperature below the first temperature before the coolant reaches the connection point.
摘要翻译：低温医疗系统包括在连接点处可连接到医疗装置的医疗装置和控制台。控制台控制医疗设备的温度。所述控制台包括第一冷却系统，所述第一冷却系统沿着冷却剂供应管线在第一温度下将冷却剂引导至所述医疗设备;以及第二冷却系统，在所述冷却剂到达所述连接点之前将所述冷却剂供应管线内的冷却剂冷却至低于所述第一温度的温度。

66. 发明申请

US20080097373A1 Distal cooling distribution system for a medical device 有权
标题翻译：用于医疗设备的远端冷却分配系统
公开(公告)号：US20080097373A1
公开(公告)日：2008-04-24
申请号：US11476416
申请日：2006-06-28
申请人： Yixin Hu , Vladimir Tzonev , Teresa Ann Mihalik , Benoit Thibault , Dan Wittenberger , Miriam Lane , Cristian Petre
发明人： Yixin Hu , Vladimir Tzonev , Teresa Ann Mihalik , Benoit Thibault , Dan Wittenberger , Miriam Lane , Cristian Petre
IPC分类号： A61M25/10 , A61M29/02 , A61M25/00 , A61M31/00
CPC分类号： A61M25/1025 , A61B18/02 , A61B2017/22051 , A61B2018/0022 , A61B2018/0212 , A61M2025/0004 , A61M2025/0175 , A61M2025/1061
摘要： The present invention may include a medical device having a handle, a catheter coupled to the handle, and an expandable element coupled to the catheter. The medical device may also include first and second elongate bodies that traverse a length of the handle and catheter. A housing may be disposed within the handle, with the housing defines a first opening able to receive a portion of the first elongate body, a second opening able to receive a portion of the second elongate body, and a third opening opposite the first and second openings able to receive a portion of both the and second elongate bodies. A separation element may be disposed within the housing, with the separation element defining a path able to receive a portion of the second elongate body, and whereby a portion of the first elongate body forms a loop around the separation element.
摘要翻译：本发明可以包括具有手柄，耦合到手柄的导管和联接到导管的可扩张元件的医疗装置。医疗装置还可以包括穿过手柄和导管的一段长度的第一和第二细长体。壳体可以设置在手柄内，其中壳体限定能够容纳第一细长主体的一部分的第一开口，能够容纳第二细长主体的一部分的第二开口，以及与第一和第二能够容纳第二细长体的一部分的开口。分离元件可以设置在壳体内，其中分离元件限定能够接收第二细长主体的一部分的路径，并且由此第一细长主体的一部分围绕分离元件形成环。

67. 发明授权

US07347856B2 Minimally invasive surgical clamp having treatment elements 有权
标题翻译：具有治疗元件的微创手术夹具
公开(公告)号：US07347856B2
公开(公告)日：2008-03-25
申请号：US10890364
申请日：2004-07-13
申请人： Dan Wittenberger , Cristian Petre , Daniel Nahon , Réal Ste-Marie , Marwan Abboud
发明人： Dan Wittenberger , Cristian Petre , Daniel Nahon , Réal Ste-Marie , Marwan Abboud
IPC分类号： A61B18/18
CPC分类号： A61B17/29 , A61B5/0408 , A61B17/122 , A61B17/2812 , A61B17/282 , A61B18/02 , A61B18/0218 , A61B18/1492 , A61B2017/00026 , A61B2017/00084 , A61B2017/00243 , A61B2017/00738 , A61B2017/2905 , A61B2017/2931 , A61B2017/2944 , A61B2018/00791 , A61B2018/00839 , A61B2018/00875 , A61B2018/0212 , A61B2018/0225 , A61B2018/0262 , A61B2018/1465
摘要： A medical device is provided having a means for actuating a pair of opposing jaw members. The jaw members are movable relative to one another from a first position, wherein the jaw members are disposed in a spaced apart relation relative to one another, to a second position, wherein the jaw members cooperate to grasp tissue therebetween. An ablation tool is connected to at least one of the jaws members, such that the jaw members are capable of conducting ablation energy through the tissue grasped therebetween.
摘要翻译：提供了具有用于致动一对相对的钳口构件的装置的医疗装置。钳口构件可从第一位置相对于彼此移动，其中钳口构件相对于彼此以间隔开的关系设置到第二位置，其中钳口构件协作以在其间抓握组织。消融工具连接到至少一个夹爪构件，使得钳口构件能够通过夹在其间夹持的组织进行消融能量。

68. 发明申请

US20080015561A1 Mesh leak detection system for a medical device 有权
标题翻译：用于医疗设备的网孔泄漏检测系统
公开(公告)号：US20080015561A1
公开(公告)日：2008-01-17
申请号：US11476405
申请日：2006-06-28
申请人： Marwan Abboud , Dan Wittenberger
发明人： Marwan Abboud , Dan Wittenberger
IPC分类号： A61B18/18
CPC分类号： G01M3/02 , A61B18/02 , A61B2017/00119 , A61B2017/22051 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61M25/0147 , A61M25/10 , A61M2205/15
摘要： The present invention provides a surgical device including an elongate body defining a fluid flow path therethrough. An expandable element may be coupled to the elongate body and placed in fluid communication with the fluid flow path. Moreover, the surgical device may include a first leak detection element at least partially surrounding a portion of the expandable element, and a second leak detection element may be provided in fluid communication with the fluid flow path. In addition, a console may be provided, where the console may be in communication with the first and second leak detection elements. Further, a supply of cryogenic fluid as well as a vacuum source may be provided in fluid communication with the fluid flow path.
摘要翻译：本发明提供一种手术装置，其包括限定通过其中的流体流动通道的细长主体。可膨胀元件可以联接到细长主体并且被放置成与流体流动路径流体连通。此外，手术装置可以包括至少部分地围绕可膨胀元件的一部分的第一泄漏检测元件，并且第二泄漏检测元件可以设置成与流体流动路径流体连通。此外，可以提供控制台，其中控制台可以与第一和第二泄漏检测元件通信。此外，可以提供与流体流动路径流体连通的低温流体以及真空源的供应。

69. 发明申请

US20070282256A1 Service loop 有权
标题翻译：服务循环
公开(公告)号：US20070282256A1
公开(公告)日：2007-12-06
申请号：US11446932
申请日：2006-06-05
申请人： Yixin Hu , Teresa Mihalik , Cristian Petre , Dan Wittenberger
发明人： Yixin Hu , Teresa Mihalik , Cristian Petre , Dan Wittenberger
IPC分类号： A61M29/00
CPC分类号： A61M25/0136 , A61B17/221 , A61B18/1492 , A61B2018/00214 , A61B2018/00898 , A61M25/1025 , A61M29/02
摘要： The present invention may include a medical device having a handle, a catheter coupled to the handle, and an expandable element coupled to the catheter. The medical device may also include first and second elongate bodies that traverse a length of the handle and catheter. A housing may be disposed within the handle, with the housing defines a first opening able to receive a portion of the first elongate body, a second opening able to receive a portion of the second elongate body, and a third opening opposite the first and second openings able to receive a portion of both the and second elongate bodies. A separation element may be disposed within the housing, with the separation element defining a path able to receive a portion of the second elongate body, and whereby a portion of the first elongate body forms a loop around the separation element.
摘要翻译：本发明可以包括具有手柄，耦合到手柄的导管和联接到导管的可扩张元件的医疗装置。医疗装置还可以包括穿过手柄和导管的一段长度的第一和第二细长体。壳体可以设置在手柄内，其中壳体限定能够容纳第一细长主体的一部分的第一开口，能够容纳第二细长主体的一部分的第二开口，以及与第一和第二能够容纳第二细长体的一部分的开口。分离元件可以设置在壳体内，其中分离元件限定能够接收第二细长主体的一部分的路径，并且由此第一细长主体的一部分围绕分离元件形成环。

70. 发明申请

US20070093799A1 Cooling system 有权
公开(公告)号：US20070093799A1
公开(公告)日：2007-04-26
申请号：US11581185
申请日：2006-10-13
申请人： Marwan Abboud , Rachid Mahrouche , Jean-Pierre Lalonde , Dan Wittenberger
发明人： Marwan Abboud , Rachid Mahrouche , Jean-Pierre Lalonde , Dan Wittenberger
IPC分类号： A61B18/04
CPC分类号： A61B18/02 , A61B2017/00084 , A61B2017/00199 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268
摘要： A cryogenic medical system includes a medical device and a console connectable to the medical device at a connection point. The console controls the temperature of the medical device. The console includes a first cooling system directing coolant to the medical device at a first temperature along a coolant supply line and a second cooling system chilling the coolant within the coolant supply line to a temperature below the first temperature before the coolant reaches the connection point.

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