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61. 发明授权

US5525389A Self-adhesive laminate for nails 失效
标题翻译：指甲自粘层压板
公开(公告)号：US5525389A
公开(公告)日：1996-06-11
申请号：US299337
申请日：1994-08-31
申请人： Hans-Rainer Hoffmann , Reinhard von Kleinsorgen , Gunter Simon , Dorothea Steinborn
发明人： Hans-Rainer Hoffmann , Reinhard von Kleinsorgen , Gunter Simon , Dorothea Steinborn
IPC分类号： A61K8/02 , A61K8/81 , A61Q3/00 , A61Q3/02 , B32B27/08 , C09J7/02
CPC分类号： A61K8/0208 , A45D29/001 , A61K8/8152 , A61Q3/00 , A61Q3/02 , B32B27/08 , Y10T428/1462
摘要： The invention relates to a self-adhesive, plasticizer-containing laminate consisting ofa) a film-forming polymeric layer containing dyestuffs and/or pigments,b) a pressure-sensitive adhesive layer, andc) a removable, preferably siliconized protective film covering the pressure-sensitive adhesive layer,the film-forming polymeric layer a) of which is at least entirely covered by a layer being resistant towards the other components of the laminate and towards the materials used in the production of the laminate. The invention further relates to the use of said laminate as artificial nails applicable to toenails or fingernails.
摘要翻译：本发明涉及一种包含a）含有染料和/或颜料的成膜聚合物层的自粘合的含增塑剂层压体，b）压敏粘合剂层，和c）可移除的，优选硅化的保护膜覆盖层该压敏粘合剂层，其成膜聚合物层a）至少完全被一层抵抗层压板的其它组分并朝向用于生产该层压材料的材料所覆盖。本发明还涉及所述层压材料作为适用于趾甲或指甲的人造指甲的用途。

62. 发明授权

US5393529A Estrogen-containing active substance plaster 失效
标题翻译：含雌激素的活性物质膏药
公开(公告)号：US5393529A
公开(公告)日：1995-02-28
申请号：US74698
申请日：1993-06-08
申请人： Hans-Rainer Hoffmann , Robert P. Klein , Reinhold Meconi , Gunter Cordes , Hans M. Wolff
发明人： Hans-Rainer Hoffmann , Robert P. Klein , Reinhold Meconi , Gunter Cordes , Hans M. Wolff
IPC分类号： A61M37/00 , A61K9/70 , A61K31/56 , A61K31/565 , A61L15/16 , A61L15/44 , A61L15/58 , C09J7/02 , A61L15/00
CPC分类号： A61K9/7061 , A61K31/565 , A61L15/58
摘要： The present invention relates to active substance plasters for the controlled release of active substances to the skin consisting of a backing layer, an adhesive film connected therewith which film is water-soluble and consists of pressure-sensitive adhesive which comprises water-swellable polymers and in which the active substance is at least partially soluble, and of a removable protective layer covering the adhesive film, in which plasters the pressure-sensitive adhesive is based on homo and/or copolymers with at least one derivative of the acrylic or methacrylic acid, and which comprise as active substances, partially or completely dissolved in the adhesive, at a concentration of 0.5 to 10.0%-wt estrogens and their pharmaceutically acceptable derivatives alone or in combination with gestagens.
摘要翻译：本发明涉及用于将活性物质控制释放到皮肤中的活性物质膏药，其由背衬层，与之连接的粘合膜，该膜是水溶性的，并且由包含水溶胀性聚合物的压敏粘合剂组成，活性物质至少部分可溶的，以及覆盖粘合剂膜的可除去的保护层，其中压敏粘合剂基于与丙烯酸或甲基丙烯酸的至少一种衍生物的均聚和/或共聚物，以及其以活性物质部分或完全溶解在粘合剂中，浓度为0.5至10.0重量％的雌激素及其药学上可接受的衍生物单独或与孕激素组合。

63. 发明授权

US08616101B2 Process and device for manufacturing a product from strip tape, especially for manufacturing a medicinal and/or active substance-containing product as well as fillable containers or sealed-margin bags 失效
标题翻译：用于从带状带制造产品的方法和装置，特别是用于制造含药物和/或活性物质的产品以及可填充容器或密封边缘袋
公开(公告)号：US08616101B2
公开(公告)日：2013-12-31
申请号：US11511213
申请日：2006-08-29
申请人： Detlev Neuland , Wolfgang Schafer , Hans-Rainer Hoffmann
发明人： Detlev Neuland , Wolfgang Schafer , Hans-Rainer Hoffmann
IPC分类号： B26D7/06 , B26D3/00 , B26D1/22
CPC分类号： B26D1/225 , A61F2013/0296 , A61K9/7023 , B65H20/00 , B65H35/02 , B65H39/16 , B65H2301/33212 , B65H2301/33222 , B65H2406/35 , Y10T83/0476 , Y10T83/0548 , Y10T83/2037 , Y10T83/2042 , Y10T83/207 , Y10T83/2185 , Y10T83/2196 , Y10T83/6472 , Y10T83/6489 , Y10T83/6584 , Y10T83/6588 , Y10T83/7851 , Y10T83/9312 , Y10T83/9403
摘要： A device for manufacturing a product from strip tape includes a roll that draws off and separates a web of material. The web of material is severed into individual strips in cooperation with a multiple circular knife roll. A vacuum conveyor channel is associated with each strip. The vacuum conveyor channel is designed such that each strip is turned on its way to the channel or through the channel by about 90°. The end of the vacuum conveyor channel brings the strips together at one site to form a unit and at that site there are provided a guide and a transport device for the further transport to conversion equipment.
摘要翻译：用于从带状带制造产品的装置包括拉出和分离材料网的辊。与多个圆形刀辊协作，将材料卷材切成单独的条带。真空输送机通道与每个条带相关联。真空输送通道被设计成使得每个条带在通道上或通过通道转动大约90°。真空输送通道的端部将条带组合在一个位置以形成单元，并且在该位置处设置有用于进一步输送到转换设备的引导件和输送装置。

64. 发明授权

US08256631B2 Closure system for containers 有权
标题翻译：集装箱封闭系统
公开(公告)号：US08256631B2
公开(公告)日：2012-09-04
申请号：US12283231
申请日：2008-09-10
申请人： Hans-Rainer Hoffmann , Rudolf Matusch
发明人： Hans-Rainer Hoffmann , Rudolf Matusch
IPC分类号： B65D39/02 , B65D41/00
CPC分类号： A61J1/065 , A61J1/062 , A61J1/1468 , B65D2251/0093
摘要： A closure system is provided for containers used for storing or administering substances in the form of liquids, pastes or powders, which includes a cap, provided with a through-hole, and a closure element, wherein the cap holds the closure element with a force fit and/or form fit on the container, in the area of the container opening that is to be closed, by a catch element present on the container. The end face which surrounds the container opening, and on which the closure element bears, comprises a depression. The closure element is a virus-proof, bacteria-proof and spore-proof film that lies on the end face and, at least in some areas, over the depression. The cap is then fitted in place, an elastomer ring or adhesive ring is arranged between the closure element and the depression and fills the depression.
摘要翻译：提供封闭系统用于容纳用于储存或施用液体，糊剂或粉末形式的物质的容器，所述容器包括设置有通孔的盖子和封闭元件，其中盖子用力通过存在于容器上的捕获元件，在容器开口的区域中，在容器上配合和/或形状配合。围绕容器开口并且封闭元件承载的端面包括凹陷。封闭元件是防病毒，防细菌和防孢子膜，位于端面，至少在某些区域，位于凹陷上。然后将盖安装在适当位置，弹性体环或粘合环布置在封闭元件和凹陷之间并填充凹陷。

65. 发明授权

US08167850B2 Cylinder/piston unit with at least three sealing elements 有权
标题翻译：具有至少三个密封元件的气缸/活塞单元
公开(公告)号：US08167850B2
公开(公告)日：2012-05-01
申请号：US12380385
申请日：2009-02-26
申请人： Hans-Rainer Hoffmann , Rudolf Matusch
发明人： Hans-Rainer Hoffmann , Rudolf Matusch
IPC分类号： A61M5/315
CPC分类号： A61M5/31513 , A61M5/30 , A61M5/3007
摘要： A cylinder/piston unit is disclosed for pre-fill, storage and release when desired of an active substance, such as a medicament. The cylinder/piston unit is provided with a cylinder and with a piston which is guided therein and which is sealed off in a sterile manner by a rubber seal, the cylinder and the piston enclosing a chamber that can be filled at least temporarily with active substance, and the cylinder having at least one discharge element at its front end. For this purpose, the piston resting in a rear position is sealed off relative to the cylinder in a sterile manner by a static front sealing element and by a static rear sealing element. Arranged spatially behind each static sealing element, there is a parking area for receiving the respective sealing element. When the piston is actuated, the individual static sealing elements are transferred from their respective sealing position into a parked position located in the parking area, and each sealing element in the parked position touches only the cylinder wall or only the piston wall. With the present invention, a cylinder/piston unit is developed which can be pre-filled and in which, despite a sterile sealing of the piston, only a slight force has to be applied in order to accelerate and/or move the piston.
摘要翻译：公开了一种用于在需要活性物质（例如药物）时进行预填充，储存和释放的气缸/活塞单元。气缸/活塞单元设置有气缸，并具有被引导到其中并且通过橡胶密封件以无菌方式密封的活塞，气缸和活塞包围可以至少临时填充活性物质的室并且该气缸在其前端具有至少一个排出元件。为此目的，静止在后部位置的活塞通过静态前密封元件和静态后密封元件以无菌方式相对于气缸被密封。在每个静态密封元件之后空间布置，存在用于接收相应的密封元件的停车区域。当活塞被致动时，各个静态密封元件从其相应的密封位置转移到位于停车区域中的停放位置，并且停放位置中的每个密封元件仅接触气缸壁或仅触及活塞壁。利用本发明，开发了可以预填充的气缸/活塞单元，并且其中尽管活塞的无菌密封，但是仅仅需要施加微小的力以加速和/或移动活塞。

66. 发明申请

US20100233244A1 Smoking Withdrawal Combination Wafer 审中-公开
标题翻译：吸烟退出组合晶片
公开(公告)号：US20100233244A1
公开(公告)日：2010-09-16
申请号：US12308428
申请日：2007-06-04
申请人： Hans-Rainer Hoffmann , Reto Brändli , Frank Theobald
发明人： Hans-Rainer Hoffmann , Reto Brändli , Frank Theobald
IPC分类号： A61K9/70 , A61K31/551 , A61K31/465 , A61K31/5513 , A61K31/55 , A61K31/5375 , A61K31/5415 , A61K31/382 , A61K31/404 , A61K31/122 , A61K31/519 , A61K31/4375 , A61K31/445 , A61K31/225 , A61P25/34 , B05D7/00
CPC分类号： A61K9/0056 , A61K9/006 , A61K9/7007
摘要： The present invention relates to a quickly decomposing oral drug preparation, for the application of active ingredient combinations for smoking withdrawal, which contains nicotine, a nicotine salt, a nicotine derivative, or a substance that reacts to nicotine, in combination with another active ingredient, and the use of such a drug preparation for the treatment of smoking withdrawal, and the use of nicotine, and/or nicotine salts or derivatives, for the production of medications for the treatment of smoking withdrawal. The active ingredient that is to be administered, in combination, for this purpose is a centrally active ingredient, preferably an antidepressant for the fighting of psychic dependency in terms of a smoking withdrawal therapy. The administration of the active ingredient combination to the patient should be handled in a simple and reliable way and should exclude side effects to a large extent.
摘要翻译：本发明涉及一种快速分解的口服药物制剂，其用于吸烟戒除的活性成分组合，其含有尼古丁，尼古丁盐，尼古丁衍生物或与尼古丁反应的物质与另一种活性成分组合，以及使用这种药物制剂来治疗戒烟，以及使用尼古丁和/或尼古丁盐或衍生物来生产用于治疗戒烟的药物。为此目的，组合施用的活性成分是一种中枢活性成分，优选用于在吸烟戒断治疗方面抵抗精神依赖的抗抑郁药。活性成分组合给患者的治疗应以简单可靠的方式处理，并应在很大程度上排除副作用。

67. 发明申请

US20090254036A1 Single-use injector with at least one draw hook 有权
标题翻译：一次性注射器至少有一个拉钩
公开(公告)号：US20090254036A1
公开(公告)日：2009-10-08
申请号：US12455964
申请日：2009-06-10
申请人： Bado Asmussen , Hans-Rainer Hoffmann , Rudolf Matusch , Uwe Wortmann
发明人： Bado Asmussen , Hans-Rainer Hoffmann , Rudolf Matusch , Uwe Wortmann
IPC分类号： A61M5/20
CPC分类号： A61M5/30 , A61M5/2033 , A61M5/24 , A61M5/3007 , A61M5/31515 , A61M2005/2073 , A61M2005/2488 , A61M2005/2492 , A61M2005/312
摘要： A single-use injector is disclosed comprising a housing (10), arranged in which are at least one mechanical spring energy store (50), at least one piston-cylinder unit (100), which can be effectively filled at least for a certain time, at least one piston-actuating ram (60) and at least one triggering unit (80). The spring energy store comprises at least one pre-tensioned spring element. The spring-loaded piston-actuating ram (60) has at least one retaining rod or hook (62), which can be moved transversely, at least in certain regions, and by means of a supporting portion supports the tensioned spring energy store on at least one resting surface of the housing. When actuation occurs, the triggering unit (80) releases the supporting portion to allow it to move away from the resting surface.
摘要翻译：公开了一种一次性注射器，其包括壳体（10），其布置有至少一个机械弹簧能量存储器（50），至少一个活塞 - 气缸单元（100），其至少可以有效地填充至少一定的至少一个活塞致动柱塞（60）和至少一个触发单元（80）。弹簧能量储存器包括至少一个预张紧弹簧元件。弹簧加载的活塞致动冲头（60）具有至少一个保持杆或钩（62），其可以至少在某些区域中横向移动，并且借助于支撑部分支撑张紧的弹簧能量储存在壳体的至少一个搁置表面。当致动发生时，触发单元（80）释放支撑部分以允许其移动远离静止表面。

68. 发明申请

US20090202597A1 Ache-Nmda Combination Wafer 审中-公开
标题翻译： Ache-Nmda组合晶圆
公开(公告)号：US20090202597A1
公开(公告)日：2009-08-13
申请号：US12308236
申请日：2007-06-04
申请人： Hans-Rainer Hoffmann , Reto Brandli , Frank Theobald
发明人： Hans-Rainer Hoffmann , Reto Brandli , Frank Theobald
IPC分类号： A61K9/00 , A61K31/13
CPC分类号： A61K45/06 , A61K9/006 , A61K31/13 , A61K31/27 , A61K31/34 , A61K31/4015 , A61K31/505 , A61K31/55 , A61K47/36 , A61K47/38 , A61K2300/00
摘要： Sheet-like pharmaceutical preparations based on hydrophilic polymers, which rapidly disintegrate upon contact with moisture and which are used to treat dementia-related illnesses The dosage form contains an active agent combination of at least two active agents which are suitable for the treatment of dementia (antidementia agents). The antidementia agents should be chosen from the group comprising acetyl cholinesterase inhibitors (AChE inhibitors) and NMDA antagonists (n-methyl-D-asparaginic acid antagonists). The use of such an active agent combination for producing an orally administrable pharmaceutical product for the treatment of dementia-related illnesses such as Alzheimer's disease, as well as a procedure for the symptomatic treatment of Alzheimer's disease by the oral administration of one of the above pharmaceutical products is also provided.
摘要翻译：基于亲水性聚合物的片状药物制剂，其在与水分接触时迅速崩解并用于治疗痴呆相关疾病。该剂型含有至少两种适用于治疗痴呆的活性剂的活性剂组合（抗增生剂）。抗增殖剂应选自乙酰胆碱酯酶抑制剂（AChE抑制剂）和NMDA拮抗剂（正甲基-D-天冬酰胺酸拮抗剂）。使用这样的活性剂组合来生产用于治疗诸如阿尔茨海默病的痴呆相关疾病的可口服给药的药物，以及通过口服给药上述药物之一来对症治疗阿尔茨海默氏病的方法还提供产品。

69. 发明申请

US20060288830A1 Process and device for manufacturing a product from strip tape, especially for manufacturing a medicinal and/or active substance-containing product as well as fillable containers or sealed-margin bags 有权
标题翻译：用于从带状带制造产品的方法和装置，特别是用于制造含药物和/或活性物质的产品以及可填充容器或密封边缘袋
公开(公告)号：US20060288830A1
公开(公告)日：2006-12-28
申请号：US11511400
申请日：2006-08-29
申请人： Detlev Neuland , Wolfgang Schafer , Hans-Rainer Hoffmann
发明人： Detlev Neuland , Wolfgang Schafer , Hans-Rainer Hoffmann
IPC分类号： B26D7/06
CPC分类号： B26D1/225 , A61F2013/0296 , A61K9/7023 , B65H20/00 , B65H35/02 , B65H39/16 , B65H2301/33212 , B65H2301/33222 , B65H2406/35 , Y10T83/0476 , Y10T83/0548 , Y10T83/2037 , Y10T83/2042 , Y10T83/207 , Y10T83/2185 , Y10T83/2196 , Y10T83/6472 , Y10T83/6489 , Y10T83/6584 , Y10T83/6588 , Y10T83/7851 , Y10T83/9312 , Y10T83/9403
摘要： A process for manufacturing a product from strip tape starting from a broad web of material includes the step of separating the web into individual strips with a smooth stripping roll, conveying each strip in a vacuum conveyor channel, turning the strips on their way to the channel or in the channel by about 90°, leading the strips together at the end of the channel one upon the other and thereafter processing the strips to form the final product.
摘要翻译：从宽幅材料开始从带状带制造产品的方法包括用平滑的剥离辊将幅材分离成单个条带的步骤，在真空输送机通道中输送每个条带，将条带转向通道或在通道中大约90°，将条带一起在通道的一端彼此接合，然后处理条以形成最终产品。

70. 发明授权

US07114422B1 Method and device for producing a product made of strip tape, especially a medical product and/or a product containing active substances as well as fillable receptacles or pouches whose edges can be sealed 有权
标题翻译：用于生产由带状带材制成的产品的方法和装置，特别是医疗产品和/或含有活性物质的产品以及其边缘可被密封的可填充的容器或袋
公开(公告)号：US07114422B1
公开(公告)日：2006-10-03
申请号：US09980199
申请日：2000-05-31
申请人： Detlev Neuland , Wolfgang Schafer , Hans-Rainer Hoffmann
发明人： Detlev Neuland , Wolfgang Schafer , Hans-Rainer Hoffmann
IPC分类号： B26D7/06 , B26D3/00 , B26D1/22
CPC分类号： B26D1/225 , A61F2013/0296 , A61K9/7023 , B65H20/00 , B65H35/02 , B65H39/16 , B65H2301/33212 , B65H2301/33222 , B65H2406/35 , Y10T83/0476 , Y10T83/0548 , Y10T83/2037 , Y10T83/2042 , Y10T83/207 , Y10T83/2185 , Y10T83/2196 , Y10T83/6472 , Y10T83/6489 , Y10T83/6584 , Y10T83/6588 , Y10T83/7851 , Y10T83/9312 , Y10T83/9403
摘要： A process for manufacturing a product from strip tape starting from a broad web of material includes the step of separating the web into individual strips with a vacuum roll, conveying each strip in a vacuum conveyor channel, turning the strips on their way to the channel or in the channel by about 90°, leading the strips together at the end of the channel one upon the other and thereafter processing the strips to form the final product.
摘要翻译：从宽带材料开始从带状带制造产品的方法包括用真空辊将幅材分离成单个条带的步骤，在真空输送机通道中输送每个条带，将条带转到通道上，在通道中约90°，将条带一起在通道的一端彼此接合，然后处理条形成最终产品。

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