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61. 发明申请

US20080227866A1 Hydroxyphenylalkadiones and Their Use for Masking Bitter Taste and/or for Intensifying Sweet Taste 审中-公开
公开(公告)号：US20080227866A1
公开(公告)日：2008-09-18
申请号：US11994452
申请日：2006-06-27
申请人： Jakob Ley , Heinz-Jurgen Bertram , Gerhard E. Krammer , Gunter Kindel
发明人： Jakob Ley , Heinz-Jurgen Bertram , Gerhard E. Krammer , Gunter Kindel
IPC分类号： A61K31/12 , C07C49/255 , A23L1/22
CPC分类号： C07C49/258 , A23F3/405 , A23L2/56 , A23L27/20 , A23L27/84 , A23L27/86 , C07C45/62 , C07C45/74 , C07C49/245 , C07C49/248 , C07C49/255
摘要： The use of a hydroxyphenylalkadione derivative of the formula (I) wherein, for X, a and Y: X is a —CH2—, —NH— or —O— group, Y is a —CH2— group and a is a single bond or X and Y are in each case a —CH— group and a is a double bond in the Z or E configuration, wherein, for R1, R2 and R3 R1 denotes hydrogen, an aliphatic radical having 1 to 4 C atoms or a —O—R5, —S—R5 or —NR5R6 group and R2 and R3 independently of one another denote hydrogen or an alkyl having 1, 2, 3, 4 or 5 C atoms which is optionally substituted by one or more oxo groups or R7—O— groups or R1 and R2 together form an aliphatic ring which contains a total of 4 to 10 carbon atoms and 0 or 1 oxygen atom, wherein the ring constituent represented by R1 and R2 is optionally substituted by one or more oxo groups and/or R7—O— groups and/or aliphatic radicals having 1 to 4 C atoms and R3 denotes hydrogen or an alkyl having 1, 2, 3, 4 or 5 C atoms which is optionally substituted by one or more oxo groups or R7—O— groups or R2 and R3 together form an aliphatic ring which contains a total of 4 to 10 carbon atoms and 0 or 1 oxygen atom, wherein the ring constituent represented by R2 and R3 is optionally substituted by one or more oxo groups and/or R7—O— groups and/or aliphatic radicals having 1 to 4 C atoms and R1 denotes hydrogen, an aliphatic radical having 1 to 4 C atoms or a —O—R5, —S—R5 or —NR5R6 group, wherein, for R4 and R: R4 and R independently of one another denote hydrogen, methyl or ethyl and wherein, for R5, R6 and R7: R5, R6 and R7 independently of one another denote hydrogen or an aliphatic radical having 1 to 4 C atoms, a salt of such a hydroxyphenylalkadione of the formula (I), a mixture comprising or consisting of two or more different hydroxyphenylalkadiones of the formula (I), wherein X, a, Y, R, R1, R2, R3, R4, R5, R6 and R7 in each case have the meaning given above, a mixture comprising or consisting of salts of two or more different hydroxyphenylalkadiones of the formula (I), wherein X, a, Y, R, R1, R2, R3, R4, R5, R6 and R7 in each case have the meaning given above, or a mixture comprising or consisting of a hydroxyphenylalkadione of the formula (I) or two or more different hydroxyphenylalkadiones of the formula (I), wherein X, a, Y, R, R1, R2, R3, R4, R5, R6 and R7 in each case have the meaning given above, and a salt of a hydroxyphenylalkadione of the formula (I) or two or more salts of different hydroxyphenylalkadiones of the formula (I), wherein X, a, Y, R, R1, R2, R3, R4, R5, R6 and R7 in each case have the meaning given above, for modifying, masking or reducing the unpleasant flavour impression of an unpleasantly tasting substance and/or for intensifying the sweet taste of a sweet-tasting substance and/or the sweet odour impression of an aroma substance which causes a sweet odour impression, as well as formulations and processes including a hydroxyphenylalkadione of the formula (I), are described.

62. 发明申请

US20080194883A1 Menthol-Containing Solids Composition 审中-公开
标题翻译：含薄荷醇固体组成
公开(公告)号：US20080194883A1
公开(公告)日：2008-08-14
申请号：US11910809
申请日：2006-04-06
申请人： Reinhard Nowak , Michael Michler , Ingo Reiss , Robert Winkel
发明人： Reinhard Nowak , Michael Michler , Ingo Reiss , Robert Winkel
IPC分类号： C07C35/12
CPC分类号： A23G3/36 , A23G4/06 , A61K8/0245 , A61K8/34 , A61K2800/56 , A61Q11/00
摘要： A menthol-containing solids composition comprising or consisting of: (a) a solid menthol component consisting of bodies having a content of 95 wt. % or more of menthol, based on the total weight of the bodies, and (b) a solid anticaking agent, comprising or consisting of particles having a particle size of not more than 100 μm, wherein particles of the anticaking agent adhere to the surface of the bodies of the menthol component, wherein the solid anticaking agent is chosen from the group consisting of calcium phosphate, magnesium phosphate, magnesium hydroxycarbonate, magnesium oxide, mixtures of magnesium oxide and silicon dioxide, mannitol, calcium silicate, magnesium silicate, talc, polydimethylsiloxane, Al, Ca, K, Na, Mg or NH4+ salts of edible fatty acids, and mixtures thereof, and wherein the content of the anticaking agent is not more than 8 wt. % and the content of the menthol component is at least 91 wt. %, in each case based on the total weight of the solids composition.
摘要翻译：含有薄荷醇的固体组合物，其包含或由以下组成：（a）由含有95重量％基于体的总重量的薄荷醇的百分比或更多，和（b）固体防结块剂，其包含或由粒径不超过100μm的颗粒组成，其中抗结块剂的颗粒粘附到表面的薄荷醇组分的主体，其中固体抗结块剂选自磷酸钙，磷酸镁，羟基碳酸镁，氧化镁，氧化镁和二氧化硅的混合物，甘露醇，硅酸钙，硅酸镁，滑石，聚二甲基硅氧烷，Al，Ca，K，Na，Mg或NH 4，可食用脂肪酸盐及其混合物，其中抗结块剂的含量不多超过8wt。％，薄荷醇成分的含量为91重量％以上。在每种情况下，基于固体组合物的总重量。

63. 发明申请

US20080161224A1 MIXTURES OF 3-(4-METHYLCYCLOHEX-3-ENYL)BUTYRALDEHYDE AND AMBROCENIDE® AND CORRESPONDING USES AND METHODS 失效
标题翻译： 3-（4-甲基环戊三烯-3-基）丁二醛和二氯甲烷的混合物和相应的用途和方法
公开(公告)号：US20080161224A1
公开(公告)日：2008-07-03
申请号：US11967652
申请日：2007-12-31
申请人： Fred Naraschkewitz , Marcus Eh
发明人： Fred Naraschkewitz , Marcus Eh
IPC分类号： A61K8/49
CPC分类号： C11D3/50 , A61K8/33 , A61K8/4973 , A61Q13/00 , C11B9/0034 , C11B9/0076
摘要： Mixtures are described which comprise or consist of 3-(4-methylcyclohex-3-enyl)butyraldehyde (limonenal) and (4aR,5R,7aS,9R)-octahydro-2,2,5,8,8,9a-hexamethyl-4H-4a,9-methanoazuleno(5,6-d)-1,3-dioxole (Ambrocenide®), the weight ratio of limonenal to Ambrocenide® being in the range from 150:1 to 2500:1.
摘要翻译：描述了包含3-（4-甲基环己-3-烯基）丁醛（柠檬烯醛）和（4aR，5R，7aS，9R） - 八氢-2,2,5,8,8,9a-六甲基 - 4H-4a，9-甲基薁（5,6-d）-1,3-二氧杂环戊烯（Ambrocenide），柠檬烯醛与Ambrocenide（R）的重量比在150:1至2500:1的范围内。

64. 发明申请

US20080138850A1 Skin Model 审中-公开
标题翻译：皮肤模型
公开(公告)号：US20080138850A1
公开(公告)日：2008-06-12
申请号：US11948543
申请日：2007-11-30
申请人： Gabriele Vielhaber , Paolo Pertile
发明人： Gabriele Vielhaber , Paolo Pertile
IPC分类号： C12Q1/02
CPC分类号： G01N33/5088
摘要： The present invention relates to the use of a pig skin sample as a skin model, particularly for the assessment of pharmacological and cosmetic effects.
摘要翻译：本发明涉及猪皮肤样品作为皮肤模型的用途，特别是用于评估药理和美容效果。

65. 发明授权

US07378121B2 Use of ferulic acid amides as flavor compounds 有权
标题翻译：使用阿魏酸酰胺作为风味化合物
公开(公告)号：US07378121B2
公开(公告)日：2008-05-27
申请号：US10325406
申请日：2002-12-20
申请人： Jakob Peter Ley , Gerhard Krammer , Sylvia Muche , Günter Kindel , Ingo Reiβ
发明人： Jakob Peter Ley , Gerhard Krammer , Sylvia Muche , Günter Kindel , Ingo Reiβ
IPC分类号： A23L1/22
CPC分类号： A23L27/204
摘要： The present invention relates to the use of various ferulic acid amides as pungent compounds and aroma compounds having a heat-generating effect in preparations used in nutrition, oral hygiene or consumed for pleasure.
摘要翻译：本发明涉及各种阿魏酸酰胺作为刺激性化合物和芳香化合物在营养，口腔卫生或消费娱乐中使用的制剂中具有发热效果的用途。

66. 发明申请

US20080095719A1 Blackberry Extract 有权
标题翻译：黑莓提取物
公开(公告)号：US20080095719A1
公开(公告)日：2008-04-24
申请号：US11629753
申请日：2005-06-16
申请人： Martina Herrmann , Holger Joppe , Helge Franke , Gabriele Vielhaber
发明人： Martina Herrmann , Holger Joppe , Helge Franke , Gabriele Vielhaber
IPC分类号： A61K36/73 , A61K8/97 , A61Q11/00
CPC分类号： A61K8/97 , A61K36/73 , A61K2800/782 , A61Q11/00 , A61Q19/08 , A61K2300/00
摘要： The invention concerns a blackberry leaf extract and its uses, in particular to slow down skin ageing, to treat the oral and pharyngeal cavity, and there in particular to prevent and slow down periodontitis and the excessive degradation of the periodontal connective tissue as well as damage to the teeth caused by matrix metalloproteinases
摘要翻译：本发明涉及黑莓叶提取物及其用途，特别是减缓皮肤老化，以治疗口腔和咽腔，特别是预防和减缓牙周炎和牙周结缔组织的过度降解以及损伤由基质金属蛋白酶引起的牙齿

67. 发明授权

US07335796B2 Process for the preparation of ketones by ozonolysis 失效
标题翻译：通过臭氧分解制备酮的方法
公开(公告)号：US07335796B2
公开(公告)日：2008-02-26
申请号：US11396902
申请日：2006-04-04
申请人： Markus Nobis
发明人： Markus Nobis
IPC分类号： C07C45/40
CPC分类号： C07D311/92 , C07C45/40 , C07C49/21 , C07C49/447 , C07D303/14 , C07D303/32
摘要： The invention relates to a process for the preparation of a ketone from a tertiary alcohol having a double bond in the alpha position, that includes the step of contacting tertiary alcohol having a double bond in the alpha position with ozone in the presence of an inorganic base under ketone-forming reaction conditions.
摘要翻译：本发明涉及一种由α位上具有双键的叔醇制备酮的方法，其包括在无机碱存在下使α位上具有双键的叔醇与臭氧接触的步骤在酮形成反应条件下。

68. 发明授权

US07332468B2 8-tetradecenal as fragrance and flavoring substance 有权
标题翻译： 8-十四烯醛作为香料和调味物质
公开(公告)号：US07332468B2
公开(公告)日：2008-02-19
申请号：US10483345
申请日：2002-07-06
申请人： Sabine Widder , Berthold Weber , Marcus Eggers , Jan Looft , Tobias Voessing , Wilhelm Pickenhagen
发明人： Sabine Widder , Berthold Weber , Marcus Eggers , Jan Looft , Tobias Voessing , Wilhelm Pickenhagen
IPC分类号： A23L1/22 , A23L2/56 , A61K8/00 , A61K8/18 , A61Q13/00
CPC分类号： C11B9/0015 , A23L27/2024
摘要： The invention relates to the use of (Z)-8-tetradecenal and of a mixture consisting of (Z)-8-tetradecanal and (E)-8-tetradecanal as an odorous or aromatic substance.
摘要翻译：本发明涉及（Z）-8-十四烯醛和由（Z）-8-十四烷醛和（E）-8-十四烷醛组成的混合物作为气味或芳族物质的用途。

69. 发明申请

US20080008660A1 Antimicrobially active compounds for treating bad breath 审中-公开
标题翻译：用于治疗口臭的抗微生物活性化合物
公开(公告)号：US20080008660A1
公开(公告)日：2008-01-10
申请号：US11812085
申请日：2007-06-14
申请人： Jurgen Rabenhorst , Arnold Machinek , Gerhard Schmaus , Martina Herrmann , Gabriele Vielhaber , Ravikumar Pillai
发明人： Jurgen Rabenhorst , Arnold Machinek , Gerhard Schmaus , Martina Herrmann , Gabriele Vielhaber , Ravikumar Pillai
IPC分类号： A61K8/30 , A61K31/16 , A61Q11/00
CPC分类号： A61K31/16 , A61K8/42 , A61Q11/00
摘要： The invention relates primarily to specific uses of a compound of the Formula 1 or of mixtures of two or more different compounds of the Formula 1, in particular for producing an antimicrobially acting agent and agent against bad breath, as well as the corresponding production methods. In addition the invention relates to specific products, in particular oral hygiene products, comprising or consisting of a compound of the Formula 1 or of a mixture of two or more different compounds of the Formula 1 wherein the radicals of the compound of the Formula 1 or of each compound of the Formula 1 in the mixture are as defined in the preceding description.
摘要翻译：本发明主要涉及式1化合物或两种或多种不同式1化合物的混合物的具体用途，特别是用于生产抗微生物作用剂和抗口臭药物以及相应的生产方法。此外，本发明涉及特定的产品，特别是口服卫生产品，其包含式I化合物或由式1的两种或更多种不同化合物的混合物组成或由其组成，其中式1化合物或的混合物中式1的每种化合物如前述描述中所定义。

70. 发明申请

US20070280892A1 Mixture With Wintergreen Odor And Flavor 失效
标题翻译：混合与冬季气味和风味
公开(公告)号：US20070280892A1
公开(公告)日：2007-12-06
申请号：US10595815
申请日：2003-11-12
申请人： Gunter Kindel , Gerhard Krammer , Horst Surburg , Hubert Loges , Arnold Machinek
发明人： Gunter Kindel , Gerhard Krammer , Horst Surburg , Hubert Loges , Arnold Machinek
IPC分类号： A61K8/00 , A61K36/534
CPC分类号： A61K8/33 , A61K8/35 , A61Q11/00 , A61Q13/00
摘要： The invention relates to a mixture of compounds having the sensory properties of winter-green, to fragrance and flavoring compositions containing said mixture and to flavored and perfumed products containing said mixture, to a method of adding a wintergreen flavor, odor or note to (non-wintergreen) flavored or perfumed products. Further the present invention relates to the use of said mixture as an enhancement, or as complete or partial replacement for methyl salicylate, in particular in chewing gum, foods, dentrifices, mouthwashes and other orally consumable products. The mixture comprises or consists of dihydroanethole, o-anisaldehyde, 1,3-dimethoxybenzene, 2′-hydroxyacetophenone, and optionally 2-methoxyacetophenone.
摘要翻译：本发明涉及具有冬绿色感觉特性的化合物的混合物，含有所述混合物的香料和调味组合物以及含有所述混合物的调味和加香产品的混合物，涉及将冬青味，气味或香料加入（非 -wintergreen）调味或香水制品。此外，本发明涉及所述混合物作为增强剂的用途，或完全或部分替代水杨酸甲酯，特别是在口香糖，食品，齿状物，漱口剂和其它口服消费品中。该混合物由二氢茴香醚，邻茴香醛，1,3-二甲氧基苯，2'-羟基苯乙酮和任选的2-甲氧基苯乙酮组成或由其组成。

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