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1. 发明申请

US20080008660A1 Antimicrobially active compounds for treating bad breath 审中-公开
标题翻译：用于治疗口臭的抗微生物活性化合物
公开(公告)号：US20080008660A1
公开(公告)日：2008-01-10
申请号：US11812085
申请日：2007-06-14
申请人： Jurgen Rabenhorst , Arnold Machinek , Gerhard Schmaus , Martina Herrmann , Gabriele Vielhaber , Ravikumar Pillai
发明人： Jurgen Rabenhorst , Arnold Machinek , Gerhard Schmaus , Martina Herrmann , Gabriele Vielhaber , Ravikumar Pillai
IPC分类号： A61K8/30 , A61K31/16 , A61Q11/00
CPC分类号： A61K31/16 , A61K8/42 , A61Q11/00
摘要： The invention relates primarily to specific uses of a compound of the Formula 1 or of mixtures of two or more different compounds of the Formula 1, in particular for producing an antimicrobially acting agent and agent against bad breath, as well as the corresponding production methods. In addition the invention relates to specific products, in particular oral hygiene products, comprising or consisting of a compound of the Formula 1 or of a mixture of two or more different compounds of the Formula 1 wherein the radicals of the compound of the Formula 1 or of each compound of the Formula 1 in the mixture are as defined in the preceding description.
摘要翻译：本发明主要涉及式1化合物或两种或多种不同式1化合物的混合物的具体用途，特别是用于生产抗微生物作用剂和抗口臭药物以及相应的生产方法。此外，本发明涉及特定的产品，特别是口服卫生产品，其包含式I化合物或由式1的两种或更多种不同化合物的混合物组成或由其组成，其中式1化合物或的混合物中式1的每种化合物如前述描述中所定义。

2. 发明申请

US20070142739A1 Sensoric method for evaluating breath 审中-公开
标题翻译：用于评估呼吸的传感方法
公开(公告)号：US20070142739A1
公开(公告)日：2007-06-21
申请号：US10564158
申请日：2004-06-24
申请人： Steffen Sonnenberg , Anja Finke , Arnold Machinek , Bianca Piper , Jurgen Rabenhorst
发明人： Steffen Sonnenberg , Anja Finke , Arnold Machinek , Bianca Piper , Jurgen Rabenhorst
IPC分类号： A61B5/08
CPC分类号： A61B5/097 , A61B5/4547 , G01N33/0011 , G01N33/497
摘要： The invention relates to a novel method of evaluating the breath of a test subject. A breath sample from a test subject is collected in a container. The microbial load of the breath sample collected in the container is reduced. The breath sample collected in the container is evaluated by a tester.
摘要翻译：本发明涉及评估测试对象的呼吸的新方法。来自测试对象的呼吸样本被收集在容器中。收集在容器中的呼吸样本的微生物负荷降低。通过测试仪评估收集在容器中的呼吸样品。

3. 发明申请

US20080279791A1 Use of Isoeugenol Methyl Ester as an Agent Against Bad Breath 审中-公开
标题翻译：异丁烯醇甲酯作为抗呼吸剂的用途
公开(公告)号：US20080279791A1
公开(公告)日：2008-11-13
申请号：US11575906
申请日：2005-09-20
申请人： Jurgen Rabenhorst , Arnold Machinek , Steffen Sonnenberg
发明人： Jurgen Rabenhorst , Arnold Machinek , Steffen Sonnenberg
IPC分类号： A61Q11/00
CPC分类号： A01N31/16 , A61K8/33 , A61Q11/00
摘要： The use of isoeugenol methyl ether is described as an agent (i) to inhibit and/or prevent the growth of and/or to destroy micro-organisms causing bad breath and/or (ii) to combat bad breath.
摘要翻译：描述异戊烯醇甲醚的用途是（i）抑制和/或防止造成口臭的微生物和/或破坏口臭和/或（ii）抵御口臭的药剂。

4. 发明授权

US09446267B2 Products comprising a flavoring agent composition 有权
标题翻译：包含调味剂组合物的产品
公开(公告)号：US09446267B2
公开(公告)日：2016-09-20
申请号：US12898893
申请日：2010-10-06
申请人： Heiko Oertling , Hubert Loges , Arnold Machinek , Ulrike Simchen , Horst Surburg
发明人： Heiko Oertling , Hubert Loges , Arnold Machinek , Ulrike Simchen , Horst Surburg
IPC分类号： A61K8/42 , A61Q11/00 , A61K8/02 , A61K8/11 , A61K8/34 , A61K8/35 , A61K8/36
CPC分类号： A61Q11/00 , A61K8/0216 , A61K8/0241 , A61K8/11 , A61K8/347 , A61K8/35 , A61K8/36 , A61K2800/244
摘要： The present invention primarily concerns teeth cleaning compounds containing menthol for use with a toothbrush, preferably tooth pastes, tooth crèmes, tooth cleaning gels or tooth powders. Such a tooth cleaning compound according to the invention contains menthol and a quantity, for masking the bitterness of the menthol, of menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) of the following formula (Ia), in particular of the following formula (Ib), i.e. L-menthane carboxylic acid-N-(4-methoxyphenyl)-amide. The present invention also concerns the use of menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) of the formulas (Ia) or (preferably) (Ib) to mask the bitter taste of menthol in a teeth cleaning compound.The present invention also concerns a method for dissolving menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) in a teeth cleaning compound and a method for masking the bitterness of menthol in a teeth cleaning compound.
摘要翻译：本发明还涉及将薄荷烷羧酸-N-（4-甲氧基苯基） - 酰胺（WS-12）溶解在牙齿清洁化合物中的方法和用于掩蔽牙齿清洁化合物中薄荷醇的苦味的方法。

5. 发明授权

US08242289B2 Alkyl-substituted tetrahydropyrans as flavoring substances 有权
标题翻译：烷基取代的四氢吡喃作为调味物质
公开(公告)号：US08242289B2
公开(公告)日：2012-08-14
申请号：US12696200
申请日：2010-01-29
申请人： Heiko Oertling , Constanze Brocke , Hubert Loges , Arnold Machinek
发明人： Heiko Oertling , Constanze Brocke , Hubert Loges , Arnold Machinek
IPC分类号： C07D309/00 , C07D315/00
CPC分类号： C07D309/04 , A23G3/36 , A23G4/06 , A23L2/39 , A23L2/56 , A23L27/2052 , A61K8/498 , A61K31/351 , A61K2800/244 , A61Q11/00
摘要： The present invention relates to alkyl-substituted tetrahydropyrans, mixtures containing these alkyl-substituted tetrahydropyrans, their respective use and corresponding flavored products.
摘要翻译：本发明涉及烷基取代的四氢吡喃，含有这些烷基取代的四氢吡喃的混合物，它们各自的用途和相应的调味产品。

6. 发明授权

US07776923B2 Use of trans-pellitorin as flavor substance 有权
标题翻译：使用透皮蛋白作为香料
公开(公告)号：US07776923B2
公开(公告)日：2010-08-17
申请号：US10483668
申请日：2003-11-13
申请人： Ian Lucas Gatfield , Jakob Peter Ley , Gerhard Krammer , Heinz-Jurgen Bertram , Ilse Loenneker , Arnold Machinek
发明人： Ian Lucas Gatfield , Jakob Peter Ley , Gerhard Krammer , Heinz-Jurgen Bertram , Ilse Loenneker , Arnold Machinek
IPC分类号： A01N37/18 , A61K31/16
CPC分类号： A23G4/06 , A23G3/346 , A23G2200/00 , A23L27/202 , C07C231/02 , C07C231/12 , C07C233/09
摘要： The invention concerns the use of 2E,4E-decadienoic acid-N-isobutylamide (trans-pellitorin) as flavorant, in particular as salivation inducing flavor substance, preferably in a foodstuff or nutrient, an oral hygienic preparation or a gourmet or snack preparation. Further, the invention concerns preparations, semi-finished preparations as well as fragrance, aroma and taste compositions, containing trans-pelletorin as well as a processes for the production of trans-pelletorin.
摘要翻译：本发明涉及使用2E，4E-癸二烯酸-N-异丁酰胺（反式 - 蛋白糊精）作为调味剂，特别是作为唾液诱导风味物质，优选在食品或营养物质，口腔卫生制剂或美食或零食制剂中。此外，本发明涉及制剂，半成品制剂以及含有反式晶状球蛋白的香料，香气和味道组合物以及生产反式丸粒蛋白的方法。

7. 发明申请

US20100226864A1 ALKYL-SUBSTITUTED TETRAHYDROPYRANS AS FLAVORING SUBSTANCES 有权
标题翻译：烷基取代的四氢呋喃作为挥发性物质
公开(公告)号：US20100226864A1
公开(公告)日：2010-09-09
申请号：US12696200
申请日：2010-01-29
申请人： Heiko Oertling , Constanze Brocke , Hubert Loges , Arnold Machinek
发明人： Heiko Oertling , Constanze Brocke , Hubert Loges , Arnold Machinek
IPC分类号： C07D309/02 , A61K31/351 , A61K8/49 , A61Q9/02 , A61Q19/00 , A61Q5/04 , A61Q5/06 , A61Q5/12 , A61P29/00 , A23L1/22
CPC分类号： C07D309/04 , A23G3/36 , A23G4/06 , A23L2/39 , A23L2/56 , A23L27/2052 , A61K8/498 , A61K31/351 , A61K2800/244 , A61Q11/00
摘要： The present invention relates to alkyl-substituted tetrahydropyrans, mixtures containing these alkyl-substituted tetrahydropyrans, their respective use and corresponding flavored products.
摘要翻译：本发明涉及烷基取代的四氢吡喃，含有这些烷基取代的四氢吡喃的混合物，它们各自的用途和相应的调味产品。

8. 发明申请

US20080274064A1 UTILIZATION OF RHINOLOGICALLY ACTIVE SUBSTANCES 有权
标题翻译：使用生物活性物质
公开(公告)号：US20080274064A1
公开(公告)日：2008-11-06
申请号：US12175156
申请日：2008-07-17
申请人： Horst Surburg , Arnold Machinek , Hubert Loges
发明人： Horst Surburg , Arnold Machinek , Hubert Loges
IPC分类号： A61K8/49 , A61Q11/00
CPC分类号： A61Q11/00 , A23G4/06 , A23L27/203 , A61K9/0056 , A61K31/075
摘要： Acyclic compounds containing an ethers functionality external to the ring can be used as rhinologically active substances. In the regions of the mouth, the throat and the airways they produce a refreshing and clearing feeling.
摘要翻译：在环外含有醚官能团的非环化合物可用作为鼻毒素活性物质。在口腔，喉咙和气道的区域，他们产生清爽清爽的感觉。

9. 发明授权

US07414079B2 Utilization of rhinologically active substances 有权
标题翻译：利用流感活性物质
公开(公告)号：US07414079B2
公开(公告)日：2008-08-19
申请号：US10626178
申请日：2003-07-24
申请人： Horst Surburg , Arnold Machinek , Hubert Loges
发明人： Horst Surburg , Arnold Machinek , Hubert Loges
IPC分类号： A61K31/075 , C07C43/00
CPC分类号： A61Q11/00 , A23G4/06 , A23L27/203 , A61K9/0056 , A61K31/075
摘要： Acyclic compounds containing an ether functionality external to the ring can be used as rhinologically active substances. In the regions of the mouth, the throat and the airways they produce a refreshing and clearing feeling.
摘要翻译：在环外含有醚官能团的非环化合物可用作为rhinological活性物质。在口腔，喉咙和气道的区域，他们产生清爽清爽的感觉。

10. 发明授权

US08569383B2 Utilization of rhinologically active substances 有权
标题翻译：利用流感活性物质
公开(公告)号：US08569383B2
公开(公告)日：2013-10-29
申请号：US12175156
申请日：2008-07-17
申请人： Horst Surburg , Arnold Machinek , Hubert Loges
发明人： Horst Surburg , Arnold Machinek , Hubert Loges
IPC分类号： A61K31/075 , A61Q11/00 , A61K9/00
CPC分类号： A61Q11/00 , A23G4/06 , A23L27/203 , A61K9/0056 , A61K31/075
摘要： A preparation for creating a clearing feeling in a pharyngeal cavity and nasal cavity comprising a rhinologically active substance of formula (I): In formula (I), variable x and substituents R1, R2 and R3 have the following meanings: x is 0 or 1, R1 denotes an alkyl group having 1 to 4 carbon atoms, R2 denotes a methyl or ethyl group, and R3 denotes a monocyclic saturated carbon system having 5, 6, 7 or 8 carbon atoms that can be unsubstituted or substituted with further alkyl groups having 1 to 4 carbon atoms or alkenyl groups having 2 to 4 carbon atoms. The compound of formula (I) can be mixed with one or more other flavor substances or aroma substances. The preparation can be an oral care composition, such as a toothpaste or a mouth wash.
摘要翻译：一种用于在咽腔和鼻腔中产生清除感的制剂，其包含式（I）的在线活性物质：在式（I）中，变量x和取代基R 1，R 2和R 3具有以下含义：x为0或1 R 1表示碳原子数为1〜4的烷基，R 2表示甲基或乙基，R 3表示可以未被取代或者被另外的烷基取代的碳原子数为5,6,7或8的单环饱和碳系， 1至4个碳原子或具有2至4个碳原子的烯基。式（I）化合物可以与一种或多种其它风味物质或芳香物质混合。制剂可以是口腔护理组合物，例如牙膏或漱口水。

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