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61. 发明申请

US20100198313A1 POWER SUPPLY MONITORING FOR AN IMPLANTABLE DEVICE 失效
标题翻译：用于可移植设备的电源监控
公开(公告)号：US20100198313A1
公开(公告)日：2010-08-05
申请号：US12725962
申请日：2010-03-17
申请人： Randolph K. ARMSTRONG , Scott A. ARMSTRONG , D. Michael INMAN , Timothy L. SCOTT
发明人： Randolph K. ARMSTRONG , Scott A. ARMSTRONG , D. Michael INMAN , Timothy L. SCOTT
IPC分类号： A61N1/378
CPC分类号： A61N1/08 , A61N1/3708 , A61N1/378
摘要： A method and an apparatus for determining a time period remaining in a useful life of an energy storage device in an implantable medical device. The method may include measuring a voltage of the energy storage device to produce a measured voltage, and comparing the measured voltage to a transition voltage. While the measured voltage is greater than or equal to the transition voltage, the time period remaining in the energy storage device's useful life is approximated based upon a function of charge depleted. While the measured voltage is less than the transition voltage, the time period remaining in the energy storage device's useful life is approximated based upon a higher order polynomial function of the measured voltage. The transition voltage corresponds to a predetermined point on a energy storage device voltage depletion curve representing the voltage across the energy storage device over time.
摘要翻译：一种用于确定可植入医疗装置中的能量存储装置的使用寿命中剩余的时间段的方法和装置。该方法可以包括测量能量存储装置的电压以产生测量的电压，并将测量的电压与转换电压进行比较。当测量的电压大于或等于转换电压时，能量存储器件的使用寿命中剩余的时间段基于电荷耗尽的函数近似。当测量的电压小于转换电压时，能量存储器件的使用寿命中剩余的时间段基于所测量的电压的较高阶多项式函数近似。转换电压对应于表示能量存储装置上的电压随时间的电压耗尽曲线上的预定点。

62. 发明授权

US07555344B2 Selective neurostimulation for treating epilepsy 有权
标题翻译：选择性神经刺激治疗癫痫
公开(公告)号：US07555344B2
公开(公告)日：2009-06-30
申请号：US11261182
申请日：2005-10-28
申请人： Steven E. Maschino , Stephen K. Brannan
发明人： Steven E. Maschino , Stephen K. Brannan
IPC分类号： A61N1/18
CPC分类号： A61M5/14276 , A61M2005/1726 , A61M2205/054 , A61M2205/3523 , A61M2205/3569 , A61M2210/0693 , A61N1/0529 , A61N1/0531 , A61N1/0534 , A61N1/36082 , A61N2/006
摘要： A method and device for treating epilepsy are disclosed which provide for electrical, chemical or magnetic stimulation of certain areas of the brain to modulate neuronal activity of areas associated with symptoms of epilepsy. Deep brain stimulation is combined with vagus nerve stimulation to enhance symptomatic relief of the disorder. Some embodiments also employ a sensing capability to optimize the therapeutic treatment regimen.
摘要翻译：公开了用于治疗癫痫的方法和装置，其提供对脑的某些区域的电，化学或磁刺激以调节与癫痫症状相关的区域的神经元活动。深部脑刺激与迷走神经刺激相结合，增强症状缓解症状。一些实施例还采用感测能力来优化治疗治疗方案。

63. 发明申请

US20090112292A1 DYNAMIC LEAD CONDITION DETECTION FOR AN IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：用于可植入医疗器械的动态引线条件检测
公开(公告)号：US20090112292A1
公开(公告)日：2009-04-30
申请号：US11925749
申请日：2007-10-26
申请人： Randolph K. Armstrong
发明人： Randolph K. Armstrong
IPC分类号： A61N1/08
CPC分类号： A61N1/3706 , A61N1/3605 , A61N1/36542 , A61N1/37241 , A61N2001/083
摘要： The present invention provides for a method, apparatus, and system for performing a dynamic detection of a lead condition associated with a lead assembly in an implantable medical device for providing a controlled current therapeutic electrical signal to a cranial nerve. A pulsed therapeutic electrical signal is provided to a portion of a patient's body. A multiplicity of feedback signals is provided. Each the signal in the multiplicity comprises a voltage signal associated with the lead assembly for a pulse in the pulsed therapeutic electrical signal. For each the feedback signal, a determination is made as to whether the voltage signal is below a predetermined threshold to create a multiplicity of voltage signal comparison results. A determination is made as to whether or not a lead condition problem exists based upon the multiplicity of voltage signal comparison results.
摘要翻译：本发明提供了一种方法，装置和系统，用于执行与可植入医疗装置中的引线组件相关联的引导条件的动态检测，用于向颅神经提供受控的当前治疗电信号。将脉冲治疗电信号提供给患者身体的一部分。提供了多种反馈信号。多重信号中的每个信号包括与用于脉冲治疗电信号中的脉冲的引线组件相关联的电压信号。对于每个反馈信号，确定电压信号是否低于预定阈值以产生多个电压信号比较结果。基于电压信号比较结果的多重性，确定是否存在引导条件问题。

64. 发明申请

US20090012590A1 Neural Conductor 审中-公开
标题翻译：神经指导
公开(公告)号：US20090012590A1
公开(公告)日：2009-01-08
申请号：US11773317
申请日：2007-07-03
申请人： Michael Inman , David Thompson
发明人： Michael Inman , David Thompson
IPC分类号： A61N1/02
CPC分类号： A61N1/0556 , A61N1/0558
摘要： Methods and devices for reducing current spread in nerve stimulation therapy are described herein. The disclosed methods and devices utilize a novel neural conductor placed between electrodes in an implantable medical device. The neural conductor provides a path for the current to pass through rather than allowing current to spread to neighboring tissues. In an embodiment, an electrode assembly for reducing current spread in nerve stimulation therapy comprises a first and a second electrode adapted to be coupled to a target nerve. In addition, the electrode assembly comprises a neural conductor which is spaced apart from the first and second electrodes.
摘要翻译：本文描述了用于减少神经刺激治疗中的电流扩散的方法和装置。所公开的方法和装置利用放置在可植入医疗装置中的电极之间的新型神经导体。神经导体提供了电流通过的路径，而不是允许电流扩散到相邻组织。在一个实施例中，用于减少神经刺激治疗中的电流扩散的电极组件包括适于与目标神经耦合的第一和第二电极。此外，电极组件包括与第一和第二电极间隔开的神经导体。

65. 发明申请

US20080183246A1 Method, apparatus and system for guiding a procedure relating to an implantable medical device 审中-公开
标题翻译：用于引导与植入式医疗装置相关的程序的方法，装置和系统
公开(公告)号：US20080183246A1
公开(公告)日：2008-07-31
申请号：US11698688
申请日：2007-01-26
申请人： Sejal B. Patel , Jason D. Begnaud , Chris G. DuPont , Albert A. Rodriguez
发明人： Sejal B. Patel , Jason D. Begnaud , Chris G. DuPont , Albert A. Rodriguez
IPC分类号： A61N1/36
CPC分类号： A61N1/37247 , A61N1/36071 , A61N1/36521 , A61N1/37 , A61N1/3706
摘要： A method, apparatus, and system, are provided for guiding a medical procedure relating to an implantable medical device operatively coupled to a cranial nerve. Communications between the implantable medical device and an external device are established. An implant procedure is performed for implanting the implantable medical device. A first diagnostic process of the implantable medical device is performed. Using the external device a first signal is received from the implantable medical device based on the first diagnostic process. A first instruction is displayed using the external device based upon the first signal received by the external device. The first instruction includes information relating to guiding the implant procedure.
摘要翻译：提供了一种方法，装置和系统，用于引导与可操作地耦合到颅神经的可植入医疗装置有关的医疗程序。建立可植入医疗器械与外部设备之间的通信。进行用于植入可植入医疗装置的植入程序。执行可植入医疗装置的第一诊断过程。使用外部设备，基于第一诊断过程从可植入医疗设备接收第一信号。基于由外部设备接收的第一信号，使用外部设备显示第一指令。第一条指令包括有关引导植入程序的信息。

66. 发明授权

US07366571B2 Neurostimulator with activation based on changes in body temperature 失效
标题翻译：基于体温变化的激活神经刺激器
公开(公告)号：US07366571B2
公开(公告)日：2008-04-29
申请号：US11009122
申请日：2004-12-10
申请人： Randolph K. Armstrong
发明人： Randolph K. Armstrong
IPC分类号： A61B5/01 , A61N1/36
CPC分类号： A61B5/01 , A61B5/4094 , A61N1/36053 , A61N1/36135
摘要： Improved methods and devices are provided for detecting and/or predicting the onset of an undesirable physiological event or neural state, such as an epileptic seizure, to facilitate rapid intervention with a treatment therapy such as neurostimulation or drug therapy. The methods and devices involve monitoring the patient's body temperature, preferably by an implanted temperature sensor, to detect a sudden change in a body temperature parameter. The temperature parameter change may comprise an increase or decrease in the patient's body temperature, time rate of change of body temperature, or a difference in a moving average temperature for a first period from that of a second period. When a parameter change is detected that exceeds a threshold, neurostimulation therapy is delivered to a neural structure of the patient.
摘要翻译：提供改进的方法和装置用于检测和/或预测不期望的生理事件或神经状态（例如癫痫发作）的发作，以促进用诸如神经刺激或药物治疗的治疗疗法的快速干预。所述方法和装置包括通过植入的温度传感器监测患者体温，以检测体温参数的突然变化。温度参数变化可以包括患者体温的增加或减少，体温变化的时间变化率，或者第一时间段的移动平均温度与第二周期的差异。当检测到超过阈值的参数变化时，将神经刺激治疗递送到患者的神经结构。

67. 发明申请

US20070255374A1 Compensation reduction in tissue stimulation therapy 有权
标题翻译：组织刺激治疗中的补偿减少
公开(公告)号：US20070255374A1
公开(公告)日：2007-11-01
申请号：US11414391
申请日：2006-04-28
申请人： Jerry Kolafa , Steven Maschino
发明人： Jerry Kolafa , Steven Maschino
IPC分类号： A61N1/00
CPC分类号： A61N1/36082
摘要： Methods and systems for reducing compensation of the body to therapy delivered by an implanted medical device are described herein. The disclosed techniques cause a change from one therapy protocol to another therapy protocol based on the occurrence of an event (e.g., time, user activations of a sensor, input from a physiological sensor, etc.). The therapy protocols of the implanted medical device differ in terms of the on-time and off-time, but effectuate the same or similar duty cycle.
摘要翻译：本文描述了用于减少身体对由植入的医疗装置递送的治疗的补偿的方法和系统。所公开的技术基于事件的发生（例如，时间，传感器的用户激活，来自生理传感器的输入等）导致从一种治疗方案到另一种治疗方案的改变。植入式医疗装置的治疗方案在接通时间和关闭时间方面不同，但是实现相同或相似的占空比。

68. 发明申请

US20070173914A1 Self-locking electrode assembly usable with an implantable medical device 审中-公开
标题翻译：可用于可植入医疗装置的自锁电极组件
公开(公告)号：US20070173914A1
公开(公告)日：2007-07-26
申请号：US11338375
申请日：2006-01-24
申请人： Shawn Kollatschny
发明人： Shawn Kollatschny
IPC分类号： A61N1/00
CPC分类号： A61N1/0556
摘要： An electrode assembly for use with an implantable medical device. The electrode assembly comprises a spine and a plurality of electrodes that protrude from away from the spine. At least two electrodes protrude away from the spine in opposing directions.
摘要翻译：一种用于可植入医疗装置的电极组件。电极组件包括脊柱和从脊柱突出的多个电极。至少两个电极在相反的方向上远离脊柱突出。

69. 发明申请

US20070173910A1 Input response override for an implantable medical device 有权
标题翻译：可植入医疗设备的输入响应覆盖
公开(公告)号：US20070173910A1
公开(公告)日：2007-07-26
申请号：US11338548
申请日：2006-01-24
申请人： Randolph Armstrong
发明人： Randolph Armstrong
IPC分类号： A61N1/00
CPC分类号： A61N1/37211 , A61N1/08 , A61N1/36114 , A61N1/3718
摘要： A method and apparatus for providing an override of an operational mode of an implantable medical device. An override input to enter an override mode is received. A determination as to whether a magnetic input has been received is made. A predetermined response to the magnetic input is blocked in response to receiving the override input.
摘要翻译：一种用于提供可植入医疗装置的操作模式的超控的方法和装置。接收到进入覆盖模式的覆盖输入。确定是否接收到磁性输入。响应于接收到超控输入，阻止对磁输入的预定响应。

70. 发明申请

US20070173890A1 Stimulation mode adjustment for an implantable medical device 审中-公开
标题翻译：可植入医疗器械的刺激模式调整
公开(公告)号：US20070173890A1
公开(公告)日：2007-07-26
申请号：US11338374
申请日：2006-01-24
申请人： Randolph Armstrong
发明人： Randolph Armstrong
IPC分类号： A61N1/36
CPC分类号： A61N1/37252 , A61N1/36082
摘要： A method and apparatus for providing for altering a neurostimulation therapy provided by an implantable medical device (IMD). A presence of a magnetic field and/or a tap input is detected. A programmed time period for altering the neurostimulation therapy is determined based upon detecting the presence of the magnetic field and/or the tap input. An alteration of the neurostimulation therapy is performed for the duration of the time period.
摘要翻译：一种用于改变由可植入医疗装置（IMD）提供的神经刺激疗法的方法和装置。检测到磁场和/或抽头输入的存在。基于检测到磁场和/或抽头输入的存在来确定用于改变神经刺激疗法的编程时间段。神经刺激疗法的改变在持续时间内进行。

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