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51. 发明授权

US4039588A Herbicidal 4-nitro-diphenyl ethers 失效
标题翻译：除草4-硝基 - 二苯醚
公开(公告)号：US4039588A
公开(公告)日：1977-08-02
申请号：US32412
申请日：1970-04-27
申请人： Harold F. Wilson , Marvin H. Fleischfresser
发明人： Harold F. Wilson , Marvin H. Fleischfresser
IPC分类号： A01N33/22 , A01N37/48 , C07C205/38 , C07C43/28
CPC分类号： C07C205/38 , A01N33/22 , A01N37/48 , C07C323/00
摘要： This invention relates to novel herbicidal compounds of the formula ##STR1## wherein X is a (C.sub.1 -C.sub.6)alkoxy group, a (C.sub.1 -C.sub.4)alkyl group, an alkoxyalkoxy group, wherein each alkyl moiety has 1 to 4 carbon atoms, a (C.sub.1 -C.sub.4)alkylamino group, a (C.sub.1 -C.sub.4)dialkylamino group, a halogen atom, a cyano group, a trifluoromethyl group, a hydroxy group, or a (C.sub.1 -C.sub.4) alkylthio group, andY is a hydrogen atom, or a halogen atom,To herbicidal compositions which contain these compounds, and to methods of controlling weeds with the herbicidal compositions.
摘要翻译：本发明涉及式IMA的新型除草化合物，其中X为（C 1 -C 6）烷氧基，（C 1 -C 4）烷基，烷氧基烷氧基，其中各烷基部分具有1至4个碳原子，（C1-C4）烷基氨基，（C1-C4）二烷基氨基，卤素原子，氰基，三氟甲基，羟基或（C1-C4）烷硫基，Y是氢原子，或卤素原子，含有这些化合物的除草剂组合物，以及用除草剂组合物控制的方法。

52. 发明授权

US4017295A Herbicidal composition 失效
标题翻译：除草成分
公开(公告)号：US4017295A
公开(公告)日：1977-04-12
申请号：US597677
申请日：1975-07-21
申请人： Ryohei Takahashi , Isao Yokomichi , Kazuyuki Maeda , Takahiro Haga
发明人： Ryohei Takahashi , Isao Yokomichi , Kazuyuki Maeda , Takahiro Haga
IPC分类号： A01N33/22 , C07C67/00 , C07C201/00 , C07C205/38 , A01N9/20
CPC分类号： C02F1/50
摘要： A herbicidal composition which comprises an active ingredient of a diphenylether having the formula ##STR1## wherein X represents a chlorine atom or a trifluoromethyl group; R represents a methyl or ethyl group and n represents an integer of 2 or 3; and an agriculturally acceptable adjuvant.
摘要翻译：一种除草组合物，其包含具有下式的二苯基醚的活性成分：其中X表示氯原子或三氟甲基; R表示甲基或乙基，n表示2或3的整数; 和农业上可接受的佐剂。

53. 发明授权

US3928450A Acetylene substituted aromatic primary amines and the process of making them 失效
标题翻译：乙炔取代芳香族伯胺及其制备方法
公开(公告)号：US3928450A
公开(公告)日：1975-12-23
申请号：US41670973
申请日：1973-11-16
申请人： HUGHES AIRCRAFT CO
发明人： BILOW NORMAN , BOSCHAN ROBERT H , LANDIS ABRAHAM L
IPC分类号： C07C205/38 , C08G73/10 , C07C93/14
CPC分类号： C08G73/10 , C07C205/38
摘要： Acetylene substituted aromatic primary amines have been prepared by a method that yields a new class of compounds which by virtue of their stereo chemistry impart greater tractability and solubility to acetylene substituted polyimide oligomers. Compounds prepared by this method are useful as intermediates in the preparation of polyimide oligomers exhibiting lower melting points and improved solubilities.
摘要翻译：乙炔取代的芳族伯胺已经通过产生新类化合物的方法制备，由于它们的立体化学赋予对乙炔取代的聚酰亚胺低聚物更大的易溶性和溶解性。通过该方法制备的化合物可用作制备具有较低熔点和改善的溶解度的聚酰亚胺低聚物的中间体。

54. 发明授权

US3888932A Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers 失效
标题翻译：除草剂4-三氟甲基-4-硝基苯基醚
公开(公告)号：US3888932A
公开(公告)日：1975-06-10
申请号：US23465672
申请日：1972-03-14
申请人： ROHM & HAAS
发明人： BAYER HORST O , SWITHENBANK COLIN , YIH ROY Y
IPC分类号： C07C17/093 , C07C37/62 , C07C205/12 , C07C205/38 , C07C205/43 , C07C205/59 , C07C255/53 , C07C275/36 , C07D303/24 , C07C43/20
CPC分类号： C07D303/24 , C07C17/093 , C07C37/62 , C07C205/12 , C07C205/38 , C07C205/43 , C07C205/59 , C07C275/36 , C07C317/00 , C07C323/00 , C07C25/02 , C07C39/26
摘要： Compounds of the formula

WHEREIN X is a hydrogen atom, a halogen atom, a trihalomethyl group, an alkyl group, or a cyano group, and Y is a hydrogen atom, a halogen atom, or a trihalomethyl group, AND COMPOSITIONS CONTAINING THESE COMPOUNDS EXHIBIT HERBICIDAL ACITIVITY.
摘要翻译：其中X为氢原子，卤素原子，三卤代甲基，烷基或氰基，Y为氢原子，卤素原子或三卤代甲基的式“IMAGE”的化合物及其组合物这些化合物展示除草活性。

55. 发明授权

US3458516A 11-(piperazinyl)dibenz(b,f)(1,4)oxazepines and analogous thiazepines 失效
标题翻译： 11-（PIPERAZINYL）DIBENZ（B，F）（1,4）氧化亚砷和类似物
公开(公告)号：US3458516A
公开(公告)日：1969-07-29
申请号：US3458516D
申请日：1968-02-16
申请人： AMERICAN CYANAMID CO
发明人： HOWELL CHARLES FREDERICK , HARDY ROBERT ALLIS JR , QUINONES NICANOR QUINONES
IPC分类号： C07C205/38 , C07D295/215 , C07D99/10 , A61K27/00 , C07D99/04
CPC分类号： C07D295/215 , C07C205/38

56. 发明授权

US3419620A 2-ethoxy-methyl-4,6-dinitro-phenol 失效
标题翻译： 2-乙氧基 - 甲基-4,6-二硝基苯酚
公开(公告)号：US3419620A
公开(公告)日：1968-12-31
申请号：US33318063
申请日：1963-12-24
申请人： BOEHRINGER SOHN INGELHEIM
发明人： HEINZ-MANFRED BECHER , RICHARD SEHRING , KARL ZEILE
IPC分类号： C07C205/23 , C07C205/26 , C07C205/34 , C07C205/37 , C07C205/38 , C07C205/42 , C07C205/43 , C07C309/66 , C07C309/73 , C07C329/04 , C07C329/06 , C07F7/22 , C07F9/12 , C07F9/165 , C07F9/18 , C07F9/24
CPC分类号： C07F9/242 , C07C205/23 , C07C205/26 , C07C205/34 , C07C205/37 , C07C205/38 , C07C205/42 , C07C205/43 , C07C309/66 , C07C309/73 , C07C329/04 , C07C329/06 , C07F7/2232 , C07F9/12 , C07F9/1653 , C07F9/18
摘要： The invention compounds of the general formula wherein X represents Hal, -ONO2, -OCOR, -O.CO.NHR, -O.CO.NR(R1), O.CO.OR, -O.SO2.R or -OR, and Y represents H, Kt+, -R,-CO.R,-CO.NHR,-CONR(R1),-SO2R, in which Hal represents a halogen atom, Kt+ is a salt-forming cation, and R and R1, which may be the same or different, each represents a straight, branched-chain, or cyclic, saturated or unsaturated alkyl group either unsubstituted or substituted by halogen, -NO2, -OH, -NH2, -CN, -COOAlkyl aryl, substituted aryl or -Q-Ar (where Q is a hetero atom and Ar is an aryl or substituted aryl group), or any such unsubstituted or substituted alkyl group the alkylene chain of which is interrupted by a hetero atom, or a substituted or unsubstituted aryl group, provided that when X represents -O.CO.CH3, Y does not represent -CO.CH3. The novel compounds may be made by reacting a compound of the formula with an appropriate halogenating, esterifying or etherifying agent, and if desired (where a compound of Formula I in which Y is hydrogen is produced) reacting the compound so formed with a base or an etherifying or esterifying agent. The esterifying and etherifying agents may be alcohols, anhydrides or acid halides. The halogenating agent may be thionyl chloride or a phosphorus halide. The esterifying agent may be nitric acid, a mono- or di-alkylcarbamic acid halide, or a carbonic or thiocarbonic acid ester halide, an organic isocyanate, an acid halide of a phosphoric or thiophosphonic acid ester or an organic sulphonyl halide.ALSO:A pesticidal composition comprises, as active ingredient, one or more compounds of the general formula: wherein X is Hal; -ONO2; -OCOR; -OCONHR; OCONRR'; -O-CO.OR; -O.SO2.R; or -OR, and Y is H; Kt+; -R; -COR; -CONHR; in which groups Hal represents halogen; Kt+ represents a salt forming cation; and R and R' (which may be the same or different) each represents a straight, branched-chain or cyclic, saturated or unsaturated alkyl group either unsubstituted or substituted by halogen, -NO, -OH, -NH2, -CN, -COO Alk, aryl, substituted aryl or -Q-Ar (where Q is a hetero atom and Ar is an aryl or substituted aryl group); or any such unsubstituted or substituted alkyl group the alkylene chain of which is interrupted by a hetero atom; or a substitued or unsubstituted aryl group; provided that when X represents the group -O.CO.CH3, Y does not represent the group -CO.CH3; together with a carrier or diluent. The composition may be in the form of a liquid composition, such as a solution, suspension or emulsion. The carrier in such cases comprises a solvent or a suspesion or emulsion base which may include a wetting dispersing or emulsifying agent. Solid compositions include dusts, wettable powders and pastes, in which the carrier comprises an inert solid material such as kaolin or kieselguhr. Compositions incorporating a gaseous carrier include aerosols. Other pest control agents may be included such as 3-amino-1,2,4-triazole or 2-chloro-4-ethylamino-6-isopropylamino triazine. The compositions have insecticidal, acaricidal, ovicidal, herbicidal or fungicidal activity.

57. 发明授权

US3154398A Herbicidal composition and method 失效
公开(公告)号：US3154398A
公开(公告)日：1964-10-27
申请号：US13513361
申请日：1961-08-31
申请人： ROHM & HAAS
发明人： HAROLD MCRAE DOUGAL
IPC分类号： A01N37/22 , C07C205/38
CPC分类号： C07C205/38 , A01N37/22 , A01N33/22 , A01N2300/00

58. 发明授权

US3061434A Novel substituted silver halide developing agents 失效
标题翻译：新型取代的卤化银显影剂
公开(公告)号：US3061434A
公开(公告)日：1962-10-30
申请号：US68040657
申请日：1957-08-26
申请人： POLAROID CORP
发明人： MILTON GREEN , SOLODAR WARREN E
IPC分类号： C07C205/38 , G03C5/30
CPC分类号： G03C5/3021 , C07C205/38

59. 发明申请

US20220251021A1 AKR1C3 INHIBITOR AND MEDICAL USE 有权
公开(公告)号：US20220251021A1
公开(公告)日：2022-08-11
申请号：US17623666
申请日：2020-06-30
申请人： ASCENTAWITS PHARMACEUTICALS, LTD.
发明人： Jianxin Duan , Anrong Li , Fanying Meng , Xiaohong Cai
IPC分类号： C07C205/38 , C07F9/6584 , C07C33/20 , C07F9/6571 , C07F9/6581
摘要： Described are compounds that act as AKR1C3 inhibitors or pharmaceutically acceptable salts or solvates or isotopically substituted compounds thereof and methods thereof.

60. 发明申请

US20180224429A1 INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS 审中-公开
公开(公告)号：US20180224429A1
公开(公告)日：2018-08-09
申请号：US15921560
申请日：2018-03-14
申请人： Ecole Polytechnique Federale de Lausanne (EPFL)
发明人： Freddy RADTKE , Rajwinder LEHAL , Viktoria REINMÜLLER , Jieping ZHU
IPC分类号： G01N33/50 , C07D213/73 , A61K45/06 , A61N5/10 , C07C205/38 , C07D213/64 , A61K31/44 , C07C217/90 , A61K31/351 , C12Q1/6897 , A61K31/09 , A61K31/407
CPC分类号： G01N33/5011 , A61K31/09 , A61K31/351 , A61K31/407 , A61K31/44 , A61K45/06 , A61N5/10 , A61P35/00 , C07C205/38 , C07C217/90 , C07D213/64 , C07D213/73 , C12Q1/6897 , G01N2333/4703 , G01N2333/705
摘要： The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.

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