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51. 发明申请

US20140024840A1 PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS 有权
标题翻译：可共聚光敏剂的制备方法
公开(公告)号：US20140024840A1
公开(公告)日：2014-01-23
申请号：US14023494
申请日：2013-09-11
申请人： Agfa Graphics NV
发明人： Johan LOCCUFIER
IPC分类号： C07C67/317 , C07C69/54 , C07D335/16
CPC分类号： C07C69/63 , C07C67/14 , C07C67/317 , C07C69/54 , C07D335/16 , C07F9/3247 , C07F9/5337
摘要： An intermediate for preparing (meth)acrylated photoinitiators according to Formula (I): wherein: R1 is selected from the group consisting of hydrogen and a methyl group; A represents a group including at least one photoinitiating moiety; L represents a n+o-valent linking group including at least one carbon atom; n and o each independently represent an integer from 1 to 4; p is equal to 0 or 1; X represents a group selected from the group consisting of Cl, Br, I, and R2SO3; and R2 represents an optionally substituted group selected from the group consisting of an alkyl group, an alkenyl group, an alkynyl group, an alkaryl group, an aralkyl group, an aryl group and a heteroaryl group. Also, a method for the preparation of (meth)acrylated photoinitiators by β-elimination of HX from the intermediate according to Formula (I).
摘要翻译：用于制备根据式（I）的（甲基）丙烯酸酯化光引发剂的中间体：其中：R1选自氢和甲基; A表示包含至少一个光引发部分的基团; L表示包含至少一个碳原子的n + O价连接基团; n和o各自独立地表示1至4的整数; p等于0或1; X表示选自Cl，Br，I和R 2 SO 3的基团; R2表示选自烷基，烯基，炔基，烷芳基，芳烷基，芳基和杂芳基中的任意取代的基团。此外，通过根据式（I）的中间体β-去除HX制备（甲基）丙烯酸酯化光引发剂的方法。

52. 发明授权

US08524425B2 Oxime ester photoinitiators 有权
标题翻译：肟酯光引发剂
公开(公告)号：US08524425B2
公开(公告)日：2013-09-03
申请号：US12598481
申请日：2008-04-28
申请人： Akira Matsumoto , Junichi Tanabe , Hisatoshi Kura , Masaki Ohwa
发明人： Akira Matsumoto , Junichi Tanabe , Hisatoshi Kura , Masaki Ohwa
IPC分类号： G02B5/20 , G03F7/031
CPC分类号： C07D409/06 , B33Y70/00 , C07D209/86 , C07D335/16 , C07D405/12 , C07D409/14 , C07D417/12
摘要： Compounds of the formula (I) and (II) M1, M2 and M3 independently of one another are no bond, a direct bond, CO, O, S, SO, SO2 or NR14; provided that at least one of M1, M2 or M3 is a direct bond, CO, O, S, SO, SO2 or NR14; M4 is a direct bond, CR″3R″4, CS, O, S, SO, or SO2; Y is S or NR18; R1 for example is hydrogen, C3-C8cycloalkyl, phenyl or napthyl, both of which are optionally substituted; R2 for example is C1-C20alkyl; R″2 has one of the meanings given for R2; R3 and R4 are for example hydrogen, halogen, C1-C20alkyl; R′3, R′4, R″3 and R″4 independently of one another have one of the meanings given for R3 and R4; and R5 is for example hydrogen, halogen, C1-C20alkyl; provided that in the compounds of the formula (I) at least two oxime ester groups are present and provided that at least one specified substituent R2 or R″2 is present; exhibit an unexpectedly good performance in photopolymerization reactions.
摘要翻译：式（I）和（II）M1，M2和M3彼此独立的化合物不是键，直接键，CO，O，S，SO，SO 2或NR 14; 条件是M1，M2或M3中的至少一个是直接键，CO，O，S，SO，SO 2或NR 14; M4是直接键，CR''3R''4，CS，O，S，SO或SO2; Y为S或NR18; R 1例如是氢，C 3 -C 8环烷基，苯基或萘基，它们都是任选被取代的; R 2例如是C 1 -C 20烷基; R'2具有R2中给出的含义之一; R3和R4是例如氢，卤素，C1-C20烷基; R 3，R'4，R“3和R”4彼此独立地具有R3和R4给出的含义之一; R5是例如氢，卤素，C1-C20烷基; 条件是在式（I）的化合物中存在至少两个肟酯基团，条件是存在至少一个特定的取代基R 2或R“2; 在光聚合反应中表现出出人意料的良好性能。

53. 发明申请

US20120190724A1 NOVEL ANTICANCER-AIDING COMPOUND, METHOD FOR PREPARING THE SAME, ANTICANCER-AIDING COMPOSITION CONTAINING THE SAME AND METHOD FOR REDUCING ANTICANCER DRUG RESISTANCE USING THE SAME 有权
标题翻译：新型抗敏剂化合物，其制备方法，含有它们的抗炎剂组合物和使用其降低抗药性药物耐药性的方法
公开(公告)号：US20120190724A1
公开(公告)日：2012-07-26
申请号：US13375217
申请日：2010-08-19
申请人： Young Hwa Na , Young Joo Kwon , Hwa Jeong Lee , Song Wha Chae , Sang Wook Woo , Hee Ju Cho
发明人： Young Hwa Na , Young Joo Kwon , Hwa Jeong Lee , Song Wha Chae , Sang Wook Woo , Hee Ju Cho
IPC分类号： A61K31/38 , C07D409/12 , C07D311/86 , A61K31/382 , C07D409/14 , A61P35/00 , C07D409/10 , C07D407/12 , C07D407/10 , C07D407/14 , C07D335/10 , A61K31/352
CPC分类号： C07D409/14 , A61K31/382 , C07D311/78 , C07D311/92 , C07D335/04 , C07D335/16 , C07D407/12 , C07D407/14 , C07D409/12
摘要： The present invention provides a novel xanthone derivative compound or a pharmaceutically acceptable salt thereof. The compound is useful as a chemosensitizer that reduces anticancer drug resistance.
摘要翻译：本发明提供一种新颖的呫吨酮衍生物化合物或其药学上可接受的盐。该化合物可用作降低抗癌药物耐药性的化学敏感剂。

54. 发明申请

US20110028585A1 PHOTOBASE GENERATOR 失效
标题翻译：光电发生器
公开(公告)号：US20110028585A1
公开(公告)日：2011-02-03
申请号：US12921713
申请日：2009-03-18
申请人： Atsushi Shiraishi , Hideki Kimura
发明人： Atsushi Shiraishi , Hideki Kimura
IPC分类号： C08J3/28 , C07F5/02
CPC分类号： C07D335/16 , C07C211/63 , C07C2603/24 , C07D487/04 , C08G59/687 , C08L63/00 , G03F7/0045 , G03F7/038
摘要： The object of the present invention is to provide a photobase generator capable of efficiently generating amines (tertiary amines and amidine) high in catalytic activity by sensing light with a wavelength of from 350 to 500 nm (especially, from 400 to 500 nm).The present invention is a photobase generator characterized in being represented by general formula (1) or (2).Y+ is a quaternary ammonio group of general formula (3) to (5), and X− is a counter anion selected from among a borate anion, a phenolate anion, and a carboxylate anion.
摘要翻译：本发明的目的是提供一种能够通过感测波长为350-500nm（特别是400-500nm）的光而有效地产生催化活性高的胺（叔胺和脒）的光碱产生剂。本发明是由通式（1）或（2）表示的光碱产生剂。 Y +是通式（3）〜（5）的季铵基，X是选自硼酸根阴离子，酚盐阴离子和羧酸根阴离子的抗衡阴离子。

55. 发明授权

US07671081B2 Multifunctional cationic photoinitiators, their preparation and use 失效
标题翻译：多官能阳离子光引发剂，其制备和用途
公开(公告)号：US07671081B2
公开(公告)日：2010-03-02
申请号：US11934387
申请日：2007-11-02
申请人： Shaun Lawrence Herlihy , Brian Rowatt , Robert Stephen Davidson
发明人： Shaun Lawrence Herlihy , Brian Rowatt , Robert Stephen Davidson
IPC分类号： A61K31/381 , C07D333/46 , C07D333/76
CPC分类号： C07D333/54 , B33Y70/00 , C07D327/08 , C07D333/76 , C07D335/16 , C07D339/08 , C08F2/50
摘要： Compounds of formula (I): wherein the substituents are as defined herein.
摘要翻译：式（I）化合物：其中取代基如本文所定义。

56. 发明授权

US07560219B2 Sulfonium salt photoinitiators and use thereof 有权
标题翻译：锍盐光引发剂及其应用
公开(公告)号：US07560219B2
公开(公告)日：2009-07-14
申请号：US11789873
申请日：2007-04-26
申请人： Yuxia Liu , Donald E. Herr
发明人： Yuxia Liu , Donald E. Herr
IPC分类号： G03F7/029
CPC分类号： C07C381/12 , C07D335/16 , C08G59/688 , G03F7/0045 , G03F7/038 , Y10S430/122 , Y10S430/123 , Y10S430/124 , Y10S430/125 , Y10S430/126
摘要： Sulfonium salt photoinitiator compositions, precursors useful in the preparation of such photoinitiators and the use of these photoinitiators in, e.g., UV curable adhesives, UV curable sealants, UV curable coating compositions, such as printing inks and varnishes, and UV curable encapsulants.
摘要翻译：锍盐光引发剂组合物，可用于制备这种光引发剂的前体和这些光引发剂在例如UV可固化粘合剂，UV可固化密封剂，UV可固化涂料组合物如印刷油墨和清漆中的用途以及UV可固化的密封剂。

57. 发明申请

US20080124751A1 COMBINATORIAL ROSAMINE LIBRARY AND USES THEREOF 有权
标题翻译：组合罗马胺及其用途
公开(公告)号：US20080124751A1
公开(公告)日：2008-05-29
申请号：US11853594
申请日：2007-09-11
申请人： Young-Tae Chang , Young-Hoon Ahn
发明人： Young-Tae Chang , Young-Hoon Ahn
IPC分类号： C12Q1/02 , C07D311/86 , C07D401/04 , C07D219/06 , C07D335/16 , C07D471/22 , G01N33/50
CPC分类号： C07D219/06 , C07D311/68 , C07D311/86 , C07D335/16 , C07D401/04 , C07D471/22 , G01N33/583 , Y10S436/80 , Y10T436/142222 , Y10T436/145555
摘要： The present invention relates to a rosamine derivative compound, as described herein, having the following structure: Also disclosed are methods of making such compounds and for using them for detection and imaging.
摘要翻译：本发明涉及如本文所述的具有以下结构的rosamine衍生物化合物：还公开了制备这些化合物并用于检测和成像的方法。

58. 发明授权

US07230121B2 Sulfoniun salts, methods for their preparation and use thereof as photoinitiators for radiation curable systems 有权
标题翻译：磺胺盐，其制备方法和用作可辐射固化体系的光引发剂
公开(公告)号：US07230121B2
公开(公告)日：2007-06-12
申请号：US10484358
申请日：2002-07-04
申请人： Gabriele Norcini , Angelo Casiraghi , Marco Visconti , Giuseppe Li Bassi
发明人： Gabriele Norcini , Angelo Casiraghi , Marco Visconti , Giuseppe Li Bassi
IPC分类号： C07F9/68 , C07F9/6553
CPC分类号： C07D339/08 , C07D333/76 , C07D335/16 , G03F7/0045 , G03F7/038
摘要： The present invention relates to sulfonium salts, to methods for their preparation and to radiation curable compositions containing them as photoinitiators.
摘要翻译：本发明涉及锍盐，其制备方法和含有它们作为光引发剂的可辐射固化组合物。

59. 发明授权

US07115750B1 Melanin concentrating hormone antagonist 失效
标题翻译：黑色素浓缩激素拮抗剂
公开(公告)号：US07115750B1
公开(公告)日：2006-10-03
申请号：US10088771
申请日：2000-09-19
申请人： Kaneyoshi Kato , Jun Terauchi , Masaaki Mori , Nobuhiro Suzuki , Yukio Shimomura , Shiro Takekawa , Yuji Ishihara
发明人： Kaneyoshi Kato , Jun Terauchi , Masaaki Mori , Nobuhiro Suzuki , Yukio Shimomura , Shiro Takekawa , Yuji Ishihara
IPC分类号： C09B5/00 , A61K3/41 , C07D209/56 , C07D487/00 , C07D491/00
CPC分类号： C07D207/277 , C07C217/74 , C07C219/28 , C07C233/29 , C07C233/44 , C07C233/80 , C07C235/42 , C07C235/50 , C07C235/56 , C07C235/64 , C07C235/84 , C07C237/40 , C07C271/28 , C07C275/42 , C07C311/21 , C07C2602/10 , C07C2602/12 , C07D209/18 , C07D209/22 , C07D209/42 , C07D211/16 , C07D211/18 , C07D211/22 , C07D211/26 , C07D211/32 , C07D211/52 , C07D211/62 , C07D211/70 , C07D213/56 , C07D213/81 , C07D213/82 , C07D215/14 , C07D215/38 , C07D233/24 , C07D239/28 , C07D239/30 , C07D261/18 , C07D263/14 , C07D263/34 , C07D265/28 , C07D271/06 , C07D295/096 , C07D295/13 , C07D295/185 , C07D307/68 , C07D307/81 , C07D311/58 , C07D317/60 , C07D319/20 , C07D333/24 , C07D333/28 , C07D333/38 , C07D335/16 , C07D405/04 , C07D405/12 , C07D413/04 , C07D413/12 , C07D493/04
摘要： A melanin-concentrating hormone antagonist which comprises a compound of the formula: wherein Ar1 is a cyclic group which may have substituents; X is a spacer having a main chain of 1 to 6 atoms; Y is a bond or a spacer having a main chain of 1 to 6 atoms; Ar is a monocyclic aromatic ring which may be condensed with a 4 to 8 membered non-aromatic ring, and may have further substituents; R1 and R2 are independently hydrogen atom or a hydrocarbon group which may have substituents; R1 and R2, together with the adjacent nitrogen atom, may form a nitrogen-containing hetero ring which may have substituents; R2 may form a spiro ring together with Ar; or R2, together with the adjacent nitrogen atom and Y, may form a nitrogen-containing hetero ring which may have substituents; or a salt thereof; which is useful as an agent for preventing or treating obesity, etc.
摘要翻译：一种黑色素浓缩激素拮抗剂，其包含下式化合物：其中Ar 1是可以具有取代基的环状基团; X是具有1至6个原子的主链的间隔物; Y是具有1至6个原子的主链的键或间隔基; Ar是可以与4至8元非芳族环稠合的单环芳环，并且可以具有其它取代基; R 1和R 2独立地是氢原子或可以具有取代基的烃基; R 1和R 2与相邻的氮原子一起可以形成可以具有取代基的含氮杂环; R 2可以与Ar一起形成螺环; 或R 2连同相邻的氮原子和Y可以形成可具有取代基的含氮杂环; 或其盐; 其可用作预防或治疗肥胖症等的药剂。

60. 发明申请

US20050191567A1 Oxime ester photoinitiators 有权
公开(公告)号：US20050191567A1
公开(公告)日：2005-09-01
申请号：US11103194
申请日：2005-04-11
申请人： Kazuhiko Kunimoto , Hidetaka Oka , Masaki Ohwa , Junichi Tanabe , Hisatoshi Kura , Jean-Luc Birbaum
发明人： Kazuhiko Kunimoto , Hidetaka Oka , Masaki Ohwa , Junichi Tanabe , Hisatoshi Kura , Jean-Luc Birbaum
IPC分类号： G03F7/027 , A61K6/083 , B41M3/00 , C07C251/50 , C07C251/62 , C07C251/66 , C07C251/68 , C07C317/28 , C07C317/32 , C07C323/47 , C07C327/30 , C07D207/32 , C07D207/335 , C07D209/86 , C07D333/20 , C07D335/16 , C07D339/08 , C08F2/50 , G02B5/20 , G03F7/00 , G03F7/004 , G03F7/029 , G03F7/031 , G03F9/00
CPC分类号： C07D207/335 , A61K6/083 , B33Y70/00 , B41M3/003 , C07C251/66 , C07C251/68 , C07C317/32 , C07C323/47 , C07C327/30 , C07D209/86 , C07D333/20 , C07D335/16 , C07D339/08 , G03F7/0007 , G03F7/0045 , G03F7/031
摘要： Compounds of the formulae I, II, III, IV and V wherein R1 i.a. is C4-C9cycloalkanoyl, C1-C12alkanoyl, C4-C6alkenoyl, or benzoyl; R2 is for example phenyl, C1-C20alkyl, C3-C8cycloalkyl, C2-C20alkanoyl, or benzoyl; Ar1 is R4S-phenyl or NR5R6-phenyl, each of which optionally is substituted; or Ar1 i.a. is optionally substituted; or Ar1 is naphthyl or anthracyl each of which is unsubstituted or substituted; or Ar1 is benzoyl, naphthalenecarbonyl, phenanthrenecarbonyl, anthracenecarbonyl or pyrenecarbonyl, each of which is unsubstituted or substituted, or Ar1 is 3,4,5-trimethoxyphenyl, phenoxyphenyl or biphenyl; Ar2 i.a. is optionally substituted, or naphthyl or anthracyl, each of which is unsubstituted or substituted, x is 2 or 3; M1 when x is 2, for example is phenylene, naphthalene, anthracylene, each of which optionally is substituted; M1, when x is 3, is a trivalent radical; M2 for example is M3 is for example C1-C12alkylene, cyclohexylene, or phenylene; n is 1-20; R3 is for example hydrogen or C1-C12alkyl; R3′ i.a. is C1-C12alkyl; substituted or —O-interrupted C2-C6alkyl; R4 is for example hydrogen, or C1-C12alkyl; and R5 and R6 independently of each other i.a. are hydrogen, C1-C12alkyl, or phenyl; are suitable as photoinitiators in particular in resist applications.

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