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51. 发明申请

US20090148396A1 BIOCOMPATIBLE BIODEGRADABLE FUMAGILLIN ANALOG CONJUGATES 失效
标题翻译：生物可降解的FUMAGILLIN模拟结合
公开(公告)号：US20090148396A1
公开(公告)日：2009-06-11
申请号：US12276856
申请日：2008-11-24
申请人： Laura C. AKULLIAN , Russell C. PETTER , John J. KANE , Charles E. HAMMOND , Mao YIN , Aleksandr YURKOVETSKIY , Cheri A. STEVENSON
发明人： Laura C. AKULLIAN , Russell C. PETTER , John J. KANE , Charles E. HAMMOND , Mao YIN , Aleksandr YURKOVETSKIY , Cheri A. STEVENSON
IPC分类号： A61K31/77 , C08F24/00 , C08F26/06 , A61P35/00 , A61K31/787
CPC分类号： C07D303/40 , A61K47/59 , C07D303/18 , C07D303/22 , C07D303/36 , C07D405/14 , C07D487/08
摘要： Fumagillin analog polymer conjugates, methods of making fumagillin analog polymer conjugates, compositions comprising a polymer conjugate of a fumagillin analog, and methods for treating cancer, or treating angiogenic diseases comprising administering to a subject in need thereof an effective amount of a polymer conjugate of a fumagillin analog, are described. Also described are novel fumagillin analogs, methods of making fumagillin analogs, compositions comprising at least one fumagillin analog, and methods for treating cancer, or treating angiogenic diseases comprising administering to a subject in need thereof an effective amount of a fumagillin analog.
摘要翻译：烟曲霉素类似物聚合物缀合物，制备烟曲霉素类似物聚合物共轭物的方法，包含烟曲霉素类似物的聚合物缀合物的组合物，以及用于治疗癌症的方法或治疗血管发生疾病的方法，包括向有需要的受试者施用有效量的烟曲霉素类似物。还描述了新的烟曲霉素类似物，制备烟曲霉素类似物的方法，包含至少一种烟曲霉素类似物的组合物，以及用于治疗癌症的方法或治疗血管发生疾病，包括向有需要的受试者施用有效量的烟曲霉素类似物。

52. 发明申请

US20080193858A1 POLYMERIZABLE COMPOUND, OPTICAL RECORDING COMPOSITION, HOLOGRAPHIC RECORDING MEDIUM AND METHOD OF RECORDING INFORMATION 失效
标题翻译：可聚合化合物，光学记录组合物，全息记录介质和记录信息的方法
公开(公告)号：US20080193858A1
公开(公告)日：2008-08-14
申请号：US12028499
申请日：2008-02-08
申请人： Hiroyuki SUZUKI , Satoru Yamada
发明人： Hiroyuki SUZUKI , Satoru Yamada
IPC分类号： G03F1/14 , C07C69/76 , G03F7/004
CPC分类号： C07C69/78 , C07C69/54 , C07C69/76 , C07C233/20 , C07C233/49 , C07C309/66 , C07C309/73 , C07C323/22 , C07D303/18 , C07D305/06 , G03F7/001 , G03F7/027 , G03F7/038
摘要： The present invention provides a polymerizable compound denoted by general formula (1). In general formula (1), A denotes an oxygen atom, sulfur atom, or NR, R denotes a hydrogen atom, alkyl group, aryl group, or heterocyclic group, X denotes a hydrogen atom, polymerizable group, optionally polymerizable group-substituted alkyl group or the like, B and C each independently denote a hydrogen atom, halogen atom, polymerizable group, optionally polymerizable group-substituted alkyl group or the like, wherein at least one from among B and C denotes a hydrogen atom and at least one from among X, Y, and Z comprises a polymerizable group, m denotes an integer ranging from 0 to 5, n denotes an integer ranging from 0 to 2, and Q denotes an elimination group.
摘要翻译：本发明提供由通式（1）表示的可聚合化合物。在通式（1）中，A表示氧原子，硫原子或NR，R表示氢原子，烷基，芳基或杂环基，X表示氢原子，可聚合基团，任选地可聚合基团取代的烷基基团等，B和C各自独立地表示氢原子，卤素原子，可聚合基团，任选可聚合基团取代的烷基等，其中B和C中的至少一个表示氢原子，并且至少一个来自在X，Y和Z中包含聚合性基团，m表示0〜5的整数，n表示0〜2的整数，Q表示消去基。

53. 发明申请

US20050107469A1 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs 有权
公开(公告)号：US20050107469A1
公开(公告)日：2005-05-19
申请号：US10942563
申请日：2004-09-16
申请人： Gee-Hong Kuo , Rui Zhang , Aihua Wang , Alan DeAngelis
发明人： Gee-Hong Kuo , Rui Zhang , Aihua Wang , Alan DeAngelis
IPC分类号： A61P3/10 , C07C59/70 , C07C323/20 , C07C323/60 , C07C323/62 , C07D213/64 , C07D303/08 , C07D303/18 , C07D317/22 , C07D319/12 , C07D319/20 , A61K31/277 , A61K31/192
CPC分类号： C07C59/70 , C07C323/20 , C07C323/60 , C07C323/62 , C07C2601/02 , C07D213/64 , C07D303/08 , C07D303/18 , C07D317/22 , C07D319/12
摘要： The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.

54. 发明申请

US20010056163A1 Macromonomer compounds, their preparation from diene compounds and their use 审中-公开
标题翻译：大分子单体化合物，其二烯化合物的制备及其应用
公开(公告)号：US20010056163A1
公开(公告)日：2001-12-27
申请号：US09896297
申请日：2001-06-29
发明人： Dominique Charmot , Philippe Chaumont , Daniel Colombani
IPC分类号： C07D327/02
CPC分类号： C08F2/38 , C07C17/013 , C07C409/16 , C07C409/20 , C07D303/18 , C07C21/14
摘要： The present invention relates to macromonomer compounds having the formula (I) where R1 is hydrogen, halogen, and optionally substituted alkyl, aryl, alkylaryl or arylalkyl radical; R2 and R3, which can be similar or different, are hydrogen, halogen, alkyl, aryl, alkylaryl, arylalkyl or alkoxy radical; R4 is an optionally substituted alkyl, aryl, alkylaryl or arylalkyl radical, or nullXR5, with R5 being hydrogen, and optionally substituted alkyl, aryl, alkylaryl or aryalkyl; X is oxygen or sulphur; A corresponds to a unit issued from at least one ethylenically unsaturated monomer; and n is comprised between 1 and 10000. The invention also relates to dienic compounds having the formula (II): H2CnullCR1nullCHnullCHnullC(R2)(R3)nullX2nullR6 wherein R1 R2, R3 and X have the same meaning as above and R6 represents R5 or a group nullCOR7 or nullCOOR7 with R7 being alkyl, aryl, alkylaryl or arylalkyl.
摘要翻译：本发明涉及具有式（I）的大分子单体化合物，其中R 1是氢，卤素和任选取代的烷基，芳基，烷基芳基或芳基烷基; R2和R3可以相同或不同，是氢，卤素，烷基，芳基，烷基芳基，芳基烷基或烷氧基; R4是任选取代的烷基，芳基，烷基芳基或芳基烷基，或-XR5，其中R5是氢，和任选取代的烷基，芳基，烷芳基或芳烷基; X是氧或硫; A对应于由至少一种烯属不饱和单体发出的单元; 本发明还涉及具有式（II）的二烯化合物：H2C = CR1-CH = CH-C（R2）（R3）-X2-R6其中R1R2，R3和X具有与上述相同，R6表示R5或-COR7或-COOR7，其中R7为烷基，芳基，烷基芳基或芳基烷基。

55. 发明授权

US4029649A Terpene aryl esters 失效
标题翻译：萜烯芳基酯
公开(公告)号：US4029649A
公开(公告)日：1977-06-14
申请号：US360853
申请日：1973-05-16
申请人： Friedrich Karrer
发明人： Friedrich Karrer
IPC分类号： C07D303/18 , C07D303/28
CPC分类号： C07D303/18 , C07D303/28
摘要： New terpene aryl ethers of the formula ##STR1## wherein Z.sub.1 and Z.sub.2 together form a carbon-carbon-bond or together are an oxygen bridge,R.sub.1 and R.sub.2 are each methyl or ethyl,Z.sub.3 and Z.sub.4 together form a carbon-carbon-bond or are each hydrogen orZ.sub.1, z.sub.2, z.sub.3 and Z.sub.4 are all hydrogen and their use for combating insects are disclosed.
摘要翻译：新的萜烯芳基醚，其中Z1和Z2一起形成碳 - 碳键或一起是氧桥，R1和R2各自为甲基或乙基，Z3和Z4一起形成碳 - 碳或各自为氢或Z 1，Z 2，Z 3和Z 4均为氢，并且其用于防治昆虫的用途被公开。

56. 发明授权

US3950328A New terpene aryl ethers 失效
标题翻译：新款牛仔裤
公开(公告)号：US3950328A
公开(公告)日：1976-04-13
申请号：US360854
申请日：1973-05-16
申请人： Friedrich Karrer
发明人： Friedrich Karrer
IPC分类号： C07D303/18 , C07D303/28
CPC分类号： C07D303/18 , C07C45/71 , C07C49/84 , C07D303/28
摘要： New terpene aryl ethers of the formula ##SPC1##WhereinZ.sub.1 and Z.sub.2 together form a carbon-carbon-bond or together are an oxygen bridge,R.sub.1 and R.sub.2 are each methyl or ethyl andR.sub.3 represents allyloxy, .beta.-chlorallyloxy, .gamma.-chlorallyloxy, Methallyloxy, acetylamino, benzoyl, benzyl, phenoxy or (methylthio)-carbonyl andR.sub.4 is hydrogen orR.sub.3 is hydrogen and R.sub.4 represents propargyloxy andTheir use for combating insects are disclosed.

57. 发明授权

US3828031A Ethers 失效
标题翻译：其他人
公开(公告)号：US3828031A
公开(公告)日：1974-08-06
申请号：US19030571
申请日：1971-10-18
申请人： CIBA GEIGY AG
发明人： KARRER F
IPC分类号： A61K35/00 , C07C43/14 , C07C45/71 , C07C49/84 , C07D303/18 , C07D303/22 , C07D303/24 , C07D303/28 , C07D1/00
CPC分类号： C07D303/22 , C07C45/71 , C07C49/84 , C07C327/00 , C07D303/18 , C07D303/24 , C07D303/28
摘要： COMPOUNDS OF THE FORMULA

1-(CH3-C(-R1)(-Z1)-CH(-Z2)-(CH2)2-C(-R2)(-Z3)-CH(-Z4)-CH2-

O-),3-R4,4-R3-BENZENE

WHEREIN Z1 AND Z2 ARE TOGETHER A CARBON CARBON BOND OR TOGETHER AN OXYGEN BRIDGE OR EACH HYDROGEN, R1 AND R2 ARE EACH METHYL, OR ETHYL, Z3 AND Z4 TOGETHER ARE A CARBON CARBON BOND, R3 IS HYDROGEN, C2-C5 ALKYLCARBONYL, CARBAMOYL, C1-C4 MONOALKYL-, C2-C4 ALKENYL-, C2-C4 ALKINYLOR ARYLCARBAMOYL, R4 IS C2-C5 ALKYLCARBONYL-, CARBAMOYL, C1-C4 MONOALKYL-, C2-C4 ALKENYL-, C2-C4 ALKINYL- OR ARYLCARBAMOYL OR R3 IS C2-C5 ALKYLCARBONL, CARBAMOYL, C1-C4 MONOALKYL-, C2-C4 ALKENYL-, C2-C4 ALKINYL- OR ARYLCARBAMOYL, R4 IS HYDROGEN, C2-C5 ALKYLCARBONYL, CARBAMOYL, C1-C4 MONOALKYL-, C2-C4 ALKENYL-, C2-C4 ALKINYLOR ARYLCARBAMOYL OR Z3 AND Z4 ARE EACH HYDROGEN AND R3 AND R4 ARE EACH HYDROGEN, C2-C5 ALKYLCARBONYL, CARBAMOYL, C1-C4 MONOAALKYL-, C2-C4 ALKENYL-, C2-C4 ALKINYL- OR ARYLCARBAMOYL. COMPOUNDS ACCORDING TO THE ABOVE FORMULA WHEREIN Z1 AND Z2 ARE TOGETHER A CARBON CARBON BOND OR AN OXYGEN BRIDGE, R1 AND R2 ARE EACH METHYL OR ETHYL, Z3 AND Z4 ARE TOGETHER A CARBON CARBON BRIDGE, R3 IS ACETYL, PROPIONYL, BUTYRYL, CARBAMOYL, MONOMETHYLCARBAMOYL, MONOETHYLCARBAMKOYL OR MONOPHENYLCARBAMOYL AND R4 IS HYDROGEN, ARE USEFUL FOR COMBATING PESTS ESPECIALLY INSECTS, REPRESENTATIONS OF THE ORDER ACARINA OR NEMATODES.

58. 发明公开

US20240239949A1 MULTIFUNCTIONAL EPOXY COMPOUND HAVING MULTIPLE LIQUID CRYSTAL CORES, AND CURED PRODUCT PRODUCED THEREFROM 审中-公开
公开(公告)号：US20240239949A1
公开(公告)日：2024-07-18
申请号：US18556977
申请日：2022-04-12
申请人： KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人： Hyeon Uk YEO , Thi en TRINH , Kyo Sun KU
IPC分类号： C08G59/22 , C07D303/18 , C07D407/12 , C08G59/50 , C08L63/00
CPC分类号： C08G59/22 , C07D303/18 , C07D407/12 , C08G59/5033 , C08L63/00
摘要： There are provided a multifunctional epoxy compound obtained by modifying two or more epoxide functional groups on terminal portions of liquid crystal molecules synthesized by bonding multiple thermotropic liquid crystal materials; and a cured product produced by reacting the compound with a curing agent. The compound and the cured product enable easy interaction between liquid crystals and exhibiting high thermal conductivity. They are usable alone as a heat-dissipating polymer, or in the form of a composite material, and are applicable as a matrix resin of a composite material.

59. 发明授权

US11858887B2 Linker compounds, methods of producing the same and uses thereof 有权
公开(公告)号：US11858887B2
公开(公告)日：2024-01-02
申请号：US16496920
申请日：2018-03-21
申请人： Shenkar College of Engineering and Design
发明人： Elizabeth Amir , Daniel Anavi
IPC分类号： C08B3/08 , C08B3/14 , C07C57/03 , C07C321/04 , C07D303/18 , C07C21/02 , C07D303/22 , C07C57/18 , C07C33/048 , C07C33/02 , C07C21/22 , C07C33/04 , C08B15/00 , C07C67/14 , C07C57/68 , C07C57/66 , C07C67/08
CPC分类号： C07C57/03 , C07C21/02 , C07C21/22 , C07C33/02 , C07C33/04 , C07C33/048 , C07C57/18 , C07C57/66 , C07C57/68 , C07C67/08 , C07C67/14 , C07C321/04 , C07D303/18 , C07D303/22 , C08B3/08 , C08B3/14 , C08B15/00
摘要： The present disclosure provides a bifunctional linker for coupling at least one functional moiety, preferably a bis-allyl propionic acid (BAPA), to a polymer-containing matrix. Also disclosed by the present disclosure are anhydrides of the bifunctional linker, processes for preparing the bifunctional linker and such anhydride, as well as surfaces, such as cellulose containing matrices, coupled with the bifunctional linker, at times, the latter carrying a functional agent.

60. 发明授权

US11780819B2 Aromatic substituted alkane-core monomers and polymers thereof for volume Bragg gratings 有权
公开(公告)号：US11780819B2
公开(公告)日：2023-10-10
申请号：US17098130
申请日：2020-11-13
申请人： META PLATFORMS TECHNOLOGIES, LLC
发明人： Lafe Purvis , Austin Lane , Matthew E. Colburn
IPC分类号： C07D303/18 , C07C321/28 , C07C271/54 , C07C271/58 , C07C333/04 , G03H1/02 , C07C321/20 , C08L33/14
CPC分类号： C07D303/18 , C07C271/54 , C07C271/58 , C07C321/20 , C07C321/28 , C07C333/04 , C08L33/14 , G03H1/0248 , G03H2001/0264 , G03H2223/24 , G03H2260/12
摘要： The disclosure provides recording materials including aromatic substituted alkane-core derivatized monomers and polymers for use in volume Bragg gratings, including, but not limited to, volume Bragg gratings for holography applications. Several structures are disclosed, including Formula I. When used in Bragg gratings applications, the monomers and polymers disclosed lead to materials with higher refractive index, low birefringence, and high transparency. The disclosed derivatized monomers and polymers can be used in any volume Bragg gratings materials, including two-stage polymer materials where a matrix is cured in a first step, and then the volume Bragg grating is written by way of a second curing step of a monomer.

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