专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

51. 发明授权

US08449838B2 Devices and methods for batch processing magnetic bead assays 有权
标题翻译：用于批量处理磁珠测定的装置和方法
公开(公告)号：US08449838B2
公开(公告)日：2013-05-28
申请号：US12839872
申请日：2010-07-20
申请人： Kashan Ali Shaikh , Christopher Michael Puleo , Jun Xie , Hansong Zeng , Li Zhu
发明人： Kashan Ali Shaikh , Christopher Michael Puleo , Jun Xie , Hansong Zeng , Li Zhu
IPC分类号： B01L3/00 , G01N33/533
CPC分类号： B01L3/00 , B01L3/502761 , B01L2200/0621 , B01L2200/0668 , B01L2300/0877 , B01L2400/043 , B03C1/0332 , B03C1/286 , B03C2201/18 , B03C2201/26 , G01N33/533 , G01N35/0098
摘要： A microfluidic device for batch processing magnetic bead assays and having one or more microfluidic sample channels, comprising, one or more micromagnets seated in a fixture; and an actuator; wherein a portion of each micromagnet is in releasable operative association with one or more of the microfluidic sample channels, and another portion of each micromagnet is in releasable operative association with the actuator; and methods for using the same.
摘要翻译：一种用于批量处理磁珠测定并具有一个或多个微流体样品通道的微流体装置，包括：一个或多个坐在固定装置中的微电磁体; 和致动器; 其中每个微磁体的一部分与一个或多个微流体样品通道可释放地相关联，并且每个微型磁体的另一部分与致动器可释放地可操作地相关联; 和使用它们的方法。

52. 发明授权

US08443983B2 Separator device 有权
标题翻译：分离器装置
公开(公告)号：US08443983B2
公开(公告)日：2013-05-21
申请号：US12764123
申请日：2010-04-21
申请人： Christopher Adey
发明人： Christopher Adey
IPC分类号： F16K31/44
CPC分类号： B03C1/286 , B03C1/284 , C02F1/488
摘要： A separator device comprising a housing having an inlet and an outlet, a magnetic separator rod or element being located within the housing to collect and separate from the flow of fluid through the housing magnetic particles carried by the flow of fluid.
摘要翻译：一种分离器装置，包括具有入口和出口的壳体，磁选机杆或元件位于壳体内以收集并分离通过由流体流携带的壳体磁性颗粒的流体流。

53. 发明授权

US08247204B2 Magnetic enrichment method, a reactor unit for micro particles and a magnet unit 有权
标题翻译：磁力富集法，微粒子反应器单元和磁体单元
公开(公告)号：US08247204B2
公开(公告)日：2012-08-21
申请号：US10576298
申请日：2004-10-20
申请人： Matti Korpela , Kenneth Rundt
发明人： Matti Korpela , Kenneth Rundt
IPC分类号： C12N13/00
CPC分类号： G01N1/28 , B03C1/286 , B03C2201/18 , B03C2201/26 , G01N33/54326 , Y10T436/11 , Y10T436/25 , Y10T436/25375 , Y10T436/2575
摘要： Magnetic enrichment method, wherein the desired biological component is collected from a solution, which component is thereafter enriched in a liquid in such a manner that by means of the micro particles attached to the magnet or attached by means of at least one magnet at least one biological component is collected in a closed reactor vessel. Thereafter at least one biological component is enriched in such a manner that the desired component is released to the solution. The reactor unit is a closed vessel, wherein the prevailing conditions are controllable. The shape and the location of the magnet unit in the reactor unit are adjusted in a preferable manner to collect the desired biological component.
摘要翻译：磁性富集方法，其中从溶液中收集所需的生物成分，该组分此后富集液体，使得通过附着在磁体上的微粒子或借助于至少一个磁体至少一个将生物成分收集在封闭的反应器容器中。此后，至少一种生物成分以使所需成分释放到溶液中的方式富集。反应器单元是密闭容器，其中主要条件是可控的。以优选方式调节反应器单元中的磁体单元的形状和位置，以收集所需的生物组分。

54. 发明授权

US08124024B2 Cassette for sample preparation 有权
标题翻译：纸盒用于样品制备
公开(公告)号：US08124024B2
公开(公告)日：2012-02-28
申请号：US12789831
申请日：2010-05-28
申请人： Jesus Ching , David Hsiang Hu , Steve Jia Chang Yu , Phillip You Fai Lee
发明人： Jesus Ching , David Hsiang Hu , Steve Jia Chang Yu , Phillip You Fai Lee
IPC分类号： B01J8/00
CPC分类号： C12N15/1013 , B01F11/0071 , B01F15/0203 , B01F15/0237 , B01F15/06 , B01F2015/0221 , B01F2015/062 , B01F2215/0037 , B01L3/502 , B01L7/00 , B01L2200/026 , B01L2200/0647 , B01L2200/0668 , B01L2200/10 , B01L2200/16 , B01L2300/042 , B01L2300/0672 , B01L2300/0867 , B01L2300/0887 , B01L2400/0478 , B01L2400/0481 , B01L2400/0487 , B01L2400/0622 , B01L2400/0633 , B01L2400/0644 , B01L2400/0683 , B03C1/01 , B03C1/286 , B03C2201/18 , B03C2201/20 , C12Q1/6806 , G01N1/38 , Y10T137/0402 , Y10T137/0407 , Y10T137/0413 , Y10T137/0419 , Y10T137/0424 , Y10T436/10 , Y10T436/11 , Y10T436/115831 , Y10T436/118339 , Y10T436/25 , Y10T436/25375 , Y10T436/255 , Y10T436/2575
摘要： A cassette for preparing a sample is disclosed herein. The cassette includes a housing, which encloses the structures and the processes used to prepare the sample.
摘要翻译：本文公开了一种用于制备样品的盒。盒子包括壳体，其包围用于制备样品的结构和过程。

55. 发明申请

US20120021931A1 DEVICES AND METHODS FOR BATCH PROCESSING MAGNETIC BEAD ASSAYS 有权
标题翻译：用于批量处理磁珠测试的装置和方法
公开(公告)号：US20120021931A1
公开(公告)日：2012-01-26
申请号：US12839872
申请日：2010-07-20
申请人： Kashan Ali Shaikh , Christopher Michael Puleo , Jun Xie , Hansong Zeng , Li Zhu
发明人： Kashan Ali Shaikh , Christopher Michael Puleo , Jun Xie , Hansong Zeng , Li Zhu
IPC分类号： C40B30/04 , C40B60/12
CPC分类号： B01L3/00 , B01L3/502761 , B01L2200/0621 , B01L2200/0668 , B01L2300/0877 , B01L2400/043 , B03C1/0332 , B03C1/286 , B03C2201/18 , B03C2201/26 , G01N33/533 , G01N35/0098
摘要： A microfluidic device for batch processing magnetic bead assays and having one or more microfluidic sample channels, comprising, one or more micromagnets seated in a fixture; and an actuator; wherein a portion of each micromagnet is in releasable operative association with one or more of the microfluidic sample channels, and another portion of each micromagnet is in releasable operative association with the actuator; and methods for using the same.
摘要翻译：一种用于批量处理磁珠测定并具有一个或多个微流体样品通道的微流体装置，包括：一个或多个坐在固定装置中的微电磁体; 和致动器; 其中每个微磁体的一部分与一个或多个微流体样品通道可释放地相关联，并且每个微型磁体的另一部分与致动器可释放地可操作地相关联; 和使用它们的方法。

56. 发明授权

US08074493B2 Pre-signaling magnetic plug 有权
标题翻译：预信号磁插头
公开(公告)号：US08074493B2
公开(公告)日：2011-12-13
申请号：US12368346
申请日：2009-02-10
申请人： Philippe Augros , Gérald Senger
发明人： Philippe Augros , Gérald Senger
IPC分类号： G01N33/20
CPC分类号： F01M11/10 , B03C1/282 , B03C1/286 , B03C2201/18 , B03C2201/24 , F01M1/18 , F01M11/0408
摘要： The invention relates to a signaling magnetic plug for a liquid circuit, the plug including a first magnetic electrode and a second magnetic electrode for coming into contact with the liquid flowing in the liquid circuit when the magnetic plug is mounted so as to detect the presence of metal particles that might be contained in the liquid. According to the invention, the plug also includes a preferably non-magnetic intermediate electrode disposed between the first and second magnetic electrodes while also being designed to be in contact with the liquid flowing in the liquid circuit when the magnetic plug is mounted, whereby said plug enables the presence of such metal particles to be detected early.
摘要翻译：本发明涉及一种用于液体回路的信号磁性塞子，该塞子包括第一磁性电极和第二磁性电极，用于在安装磁性塞时与在液体回路中流动的液体接触，以便检测是否存在可能含在液体中的金属颗粒。根据本发明，插头还包括设置在第一和第二磁极之间的优选非磁性中间电极，同时还设计成当安装磁性塞时与在液体回路中流动的液体接触，由此所述插头使得能够及早检测这种金属颗粒的存在。

57. 发明授权

US08071395B2 Methods and apparatus for magnetic separation of cells 有权
标题翻译：细胞磁分离的方法和装置
公开(公告)号：US08071395B2
公开(公告)日：2011-12-06
申请号：US12333213
申请日：2008-12-11
申请人： Ronald W. Davis , Stefanie S. Jeffrey , Michael N. Mindrinos , R. Fabian Pease , Ashley Ann Powell , AmirAli Hajhossein Talasaz
发明人： Ronald W. Davis , Stefanie S. Jeffrey , Michael N. Mindrinos , R. Fabian Pease , Ashley Ann Powell , AmirAli Hajhossein Talasaz
IPC分类号： G01N33/551
CPC分类号： G01N33/54333 , B03C1/01 , B03C1/286 , B03C2201/18 , B03C2201/26
摘要： Described here is an automated robotic device that isolates circulating tumor cells (CTCs) or other biological structures with extremely high purity. The device uses powerful magnetic rods covered in removable plastic sleeves. These rods sweep through blood samples, capturing, e.g., cancer cells labeled with antibodies linked to magnetically responsive particles such as superparamagnetic beads. Upon completion of the capturing protocol, the magnetic rods undergo several rounds of washing, thereby removing all contaminating blood cells. The captured target cells are released into a final capture solution by removing the magnetic rods from the sleeves. Additionally, cells captured by this device show no reduced viability when cultured after capture. Cells are captured in a state suitable for genetic analysis. Also disclosed are methods for single cell analysis. Being robotic allows the device to be operated with high throughput.
摘要翻译：这里描述了一种自动化的机器人装置，其以非常高的纯度分离循环肿瘤细胞（CTC）或其他生物结构。该设备使用强大的磁棒覆盖在可拆卸的塑料袖子。这些棒穿过血液样品，捕获例如用与磁性响应颗粒例如超顺磁珠连接的抗体标记的癌细胞。在完成捕获方案后，磁棒经历几轮洗涤，从而除去所有污染的血细胞。通过从袖子中取出磁棒将捕获的靶细胞释放到最终的捕获溶液中。此外，由该装置俘获的细胞在捕获后培养时显示出不降低的活力。以适合于遗传分析的状态捕获细胞。还公开了用于单细胞分析的方法。机器人允许设备以高吞吐量运行。

58. 发明授权

US08066877B2 Apparatus for magnetic field and magnetic gradient enhanced filtration 有权
标题翻译：用于磁场和磁梯度强化过滤的装置
公开(公告)号：US08066877B2
公开(公告)日：2011-11-29
申请号：US11353659
申请日：2006-02-14
申请人： Benjamin Fuchs , Christian Hoffman , Karsten Keller
发明人： Benjamin Fuchs , Christian Hoffman , Karsten Keller
IPC分类号： B01D35/06 , B01D29/00
CPC分类号： B01D35/06 , B03C1/286 , B03C1/30 , B03C2201/18
摘要： This invention relates to various apparatus for carrying out cake-filtration solid-liquid separation processes in which the solid-liquid mixture is subjected to a homogeneous magnetic field, a magnetic field gradient or both and cake-filtration.
摘要翻译：本发明涉及用于进行滤饼过滤固液分离方法的各种装置，其中固液混合物经受均匀的磁场，磁场梯度或两者和滤饼过滤。

59. 发明授权

US07976704B2 Filtration device 有权
标题翻译：过滤装置
公开(公告)号：US07976704B2
公开(公告)日：2011-07-12
申请号：US12466916
申请日：2009-05-15
申请人： Minoru Tashiro
发明人： Minoru Tashiro
IPC分类号： B03C1/02 , B01D35/06
CPC分类号： B01D35/06 , B03C1/032 , B03C1/286 , B03C1/288 , B03C2201/18 , B23Q11/1069
摘要： A filtration device is provided with a filter tank, filter media unit, and magnet. The filter media unit includes a filter media accommodation case and a large number of magnetic granular filter media. The magnet is movable between first and second positions. In the first position, a magnetic field is applied to the magnetic granular filter media, so that the magnetic granular filter media magnetically attract one another. In the second position, magnetic attraction between the magnetic granular filter media is canceled. The filter media accommodation case includes a nonmagnetic mesh member of a nonmagnetic material and magnetism intensification plate of a magnetic material. When the magnet is in the first position, the magnetic granular filter media and nonmagnetic mesh member are located between the magnetism intensification plate and the magnet.
摘要翻译：过滤装置设有过滤罐，过滤介质单元和磁体。过滤介质单元包括过滤介质容纳盒和大量的磁性颗粒过滤介质。磁体可在第一和第二位置之间移动。在第一位置，将磁场施加到磁性粒状过滤介质上，使得磁性粒状过滤介质彼此磁吸引。在第二位置，磁性粒状过滤介质之间的磁吸引力被消除。过滤介质容纳箱包括非磁性材料的非磁性网状构件和磁性材料的磁力增强板。当磁体处于第一位置时，磁性粒状过滤介质和非磁性网状构件位于磁力强化板和磁体之间。

60. 发明授权

US07927495B2 Separation and cleaning of a suspension comprising magnetic microparticles 有权
标题翻译：分离和清洁包含磁性微粒的悬浮液
公开(公告)号：US07927495B2
公开(公告)日：2011-04-19
申请号：US10597036
申请日：2005-01-04
申请人： Konstantin Lutze
发明人： Konstantin Lutze
IPC分类号： B01D35/06 , B03C1/00 , G01N33/553
CPC分类号： G01N33/54326 , B03C1/286 , G01N35/0098 , G01N35/026 , G01N2035/0415 , Y10S436/806 , Y10T436/25375
摘要： A device (10) is described for automatically separating solid and liquid phases of a suspension (78) and for purifying magnetic microparticles (76) loaded with organic, e.g., biological or biochemical substances. The device includes a process area (12) with devices, which move in a cyclic manner for transporting the magnetic microparticles (76) in the x-direction. A first guide (14) is used for supplying sample containers (P) in the x-direction and second guides (18) are used for supplying reagent containers (R) in the y-direction to the process area (12). The second guides (18) in the y-direction extend at an angle (α) of 30 to 150 ° to the x-direction. A carrier element (24), including carrier plates (24a, 24b, 24c) can be moved back and forth in the x-direction and can be lifted and lowered in the z-direction. The reagent containers (R) can be positioned according to the grid of the transfer elements (28), shown configured as rod-shaped permanent magnets or electromagnets, by introduction into the process area (12), taking place at an angle (α) and can be rejected by ejection in the same direction into a waste collector.
摘要翻译：描述了用于自动分离悬浮液（78）的固相和液相的装置（10）并用于净化装有有机物（例如生物或生化物质）的磁性微粒（76）。该装置包括具有装置的处理区域（12），该装置以循环方式移动，以在x方向上传送磁性微粒（76）。第一引导件（14）用于在x方向上供应样品容器（P），第二引导件（18）用于向处理区域（12）向y方向供应试剂容器（R）。沿y方向的第二引导件（18）以与x方向成30度至150度的角度（α）延伸。包括承载板（24a，24b，24c）的载体元件（24）可以沿x方向前后移动，并且可以在z方向上升降。试剂容器（R）可以通过引入到处理区域（12）中，以角度（α）发生，根据传送元件（28）的格栅定位，示出为杆状永磁体或电磁体，并且可以通过以相同的方向喷射到废物收集器中而被拒绝。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式