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51. 发明申请

US20080101971A1 Multicellular pump and fluid delivery device 有权
标题翻译：多细胞泵和流体输送装置
公开(公告)号：US20080101971A1
公开(公告)日：2008-05-01
申请号：US11901565
申请日：2007-09-18
申请人： Felix Mayer
发明人： Felix Mayer
IPC分类号： F04B23/06
CPC分类号： F04B13/00 , A61M5/14586 , A61M5/172 , F04B19/006 , F04B43/043 , F04B43/14 , F04B49/22 , F16K99/0001 , F16K99/003 , F16K99/0032 , F16K99/0044 , F16K2099/0084 , F16K2099/0086 , F16K2099/0094
摘要： The pump is provided with a plurality of pumping chambers and electrically activatable valves. An elastic membrane is arranged in each pumping chamber and divides the same into a first and a second chamber section. Each valve is connected to the second chamber section of a pumping chamber. When a pressure drop is applied over the valve and the valve is activated (i.e. opened), the pressure in the second chamber section changes, which causes the membrane to move, which in turn leads to a change of the volumes of both chamber sections. This e.g. allows to pump well-defined amounts of fluid from the chamber sections to a drug dispensing device.
摘要翻译：泵设置有多个泵送室和电激活阀。在每个泵送室中布置有弹性膜，并将其分成第一和第二室部分。每个阀连接到泵送室的第二室部分。当在阀上施加压降并且阀被启动（即打开）时，第二室部分中的压力改变，这导致膜移动，这又导致两个室部分的体积变化。例如允许将良好限定量的流体从腔室部分泵送到药物分配装置。

52. 发明申请

US20080015406A1 External Mechanical Pressure Sensor for Gastric Band Pressure Measurements 有权
标题翻译：用于胃带压力测量的外部机械压力传感器
公开(公告)号：US20080015406A1
公开(公告)日：2008-01-17
申请号：US11668122
申请日：2007-01-29
申请人： Daniel Dlugos , Amy Poeppelman , David Yates
发明人： Daniel Dlugos , Amy Poeppelman , David Yates
IPC分类号： A61F2/02
CPC分类号： A61F5/0053 , A61B17/12013 , A61B17/1355 , A61B2090/064 , A61F5/0003 , A61M5/1452 , A61M5/14586 , A61M5/486 , A61M2005/14533 , A61M2205/073 , A61M2205/3331
摘要： A merely exemplary external pressure sensing system comprises a connecting member and a pressure sensor. The connecting member is operable to connect to a syringe barrel and a needle. The connecting member comprises a conduit permitting communication of fluid from the syringe barrel to the needle when the connecting member is connected to the syringe barrel and the needle. The pressure sensor is in communication with the conduit. The pressure sensor is configured to sense pressure of fluid within the connecting member. The connecting member is configured to permit the pressure sensor to sense the pressure of the fluid while the fluid is communicated from the barrel to the needle. The pressure sensor is configured to provide a visual indication of sensed pressure. The visual indication may be provided by a variety of components, including but not limited to a diaphragm, a disc, a needle, or a slider.
摘要翻译：仅仅示例性的外部压力感测系统包括连接构件和压力传感器。连接构件可操作以连接到注射器筒和针。连接构件包括当连接构件连接到注射器筒和针时允许流体从注射器筒连接到针的导管。压力传感器与导管连通。压力传感器构造成感测连接构件内的流体的压力。连接构件构造成允许压力传感器感测流体的压力，同时流体从筒连通到针。压力传感器被配置为提供感测压力的视觉指示。视觉指示可以由各种部件提供，包括但不限于隔膜，盘，针或滑块。

53. 发明申请

US20070219597A1 Adhesive and peripheral systems and methods for medical devices 有权
标题翻译：医疗器械的粘合剂和外围系统和方法
公开(公告)号：US20070219597A1
公开(公告)日：2007-09-20
申请号：US11704897
申请日：2007-02-09
申请人： Dean Kamen , Larry Gray , Russell Beavis
发明人： Dean Kamen , Larry Gray , Russell Beavis
IPC分类号： A61N1/00
CPC分类号： A61M5/5086 , A61B5/0024 , A61B5/1427 , A61B5/6833 , A61B2560/0412 , A61J1/20 , A61M5/1413 , A61M5/142 , A61M5/14212 , A61M5/14216 , A61M5/14224 , A61M5/14244 , A61M5/14248 , A61M5/1452 , A61M5/14586 , A61M5/158 , A61M5/162 , A61M5/168 , A61M5/16804 , A61M5/16809 , A61M5/16813 , A61M5/16831 , A61M5/16886 , A61M5/172 , A61M5/1723 , A61M5/365 , A61M2005/1402 , A61M2005/14208 , A61M2005/14252 , A61M2005/14268 , A61M2005/14506 , A61M2005/1583 , A61M2005/1585 , A61M2005/1586 , A61M2005/16863 , A61M2205/0266 , A61M2205/0294 , A61M2205/04 , A61M2205/16 , A61M2205/18 , A61M2205/3303 , A61M2205/3331 , A61M2205/3337 , A61M2205/3368 , A61M2205/3375 , A61M2205/3379 , A61M2205/3523 , A61M2205/3546 , A61M2205/3569 , A61M2205/3576 , A61M2205/3592 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/8206 , A61M2205/8237 , A61M2206/22 , A61M2207/00 , A61M2209/045 , A61M2230/201 , G01F22/00 , G05B23/02 , G05D7/0647 , G05D7/0676 , G08C17/02 , H04B7/2609 , Y10T29/49236 , Y10T29/494 , Y10T29/49412 , Y10T29/49826
摘要： A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.
摘要翻译：中继器系统可以通过使用中继器和用户接口来控制泵。胶粘贴片系统可用于将泵或其它物体固定在人体上。这种粘合贴片系统可以包括两组粘合剂构件，每个构件在至少一侧上包括粘合剂材料以附接到身体。第一组的构件间隔开以允许第二组的构件在设置在第一组的构件之间的空间中附接到主体，并且第二组的构件间隔开以允许第一组的构件分离从身体没有分离第二组的成员。此外，为个人泵系统提供了填充站和基站。

54. 发明申请

US20060259016A1 Reduced size implantable pump 失效
公开(公告)号：US20060259016A1
公开(公告)日：2006-11-16
申请号：US11126101
申请日：2005-05-10
申请人： Bernd Steinbach
发明人： Bernd Steinbach
IPC分类号： A61K9/22
CPC分类号： A61M5/14276 , A61K9/0024 , A61M5/141 , A61M5/14586 , A61M5/16813
摘要： A variable hydraulic resistor for use with implantable pumps is disclosed. The variable hydraulic resistor according to the present invention is particularly useful in varying the flow rate of a medication fluid from an otherwise constant flow implantable pump. An implantable pump is also disclosed, which does not require a complicated clinching system or the like, and which may include an undulating membrane and chamber design to reduce the height of the pump.

55. 发明授权

US07108686B2 Implantable, refillable infusion device and septum replacement kit 有权
标题翻译：可植入，可再灌注输液装置和隔膜更换套件
公开(公告)号：US07108686B2
公开(公告)日：2006-09-19
申请号：US10169821
申请日：2001-01-11
申请人： Paul Burke , Kenneth A. Fine
发明人： Paul Burke , Kenneth A. Fine
IPC分类号： A61K9/22 , A61M37/00 , A61M31/00
CPC分类号： A61M5/14276 , A61M5/14586 , A61M5/14593 , A61M2209/045
摘要： An implantable infusion device (10) includes a lightweight, inert housing (12) which contains an infusate (18) for administration to a patient, and an enclosed, gas-impermeable variable volume chamber (30) which contains a pressure source, such as propellant, mechanical spring, or the like. The variable volume chamber may be in the form of a rigid-walled expandable bellows structure or a nonstretchable flexible bag and is attached to the housing so as not to obstruct the entry port for introduction of infusate. A recharging fluid flow path (31) is provided adjacent to where the variable volume chamber is attached to the housing. The infusate is delivered from the device via a catheter in response to expansion of the variable volume chamber against the volume of infusate in the housing. A separate bolus injection port (38) is provided which allows infusate to be safely introduced directly into the catheter and overrides the controlled pressure-driven delivery. The lightweight housing may include integrally formed needle stops (32 and 34) and suture fastening loops (36).
摘要翻译：植入式输注装置（10）包括轻量级惰性壳体（12），其容纳用于向患者施用的输液管（18），以及封闭的气体不可渗透的可变体积腔室（30），其包含压力源，例如推进剂，机械弹簧等。可变体积室可以是刚性可膨胀波纹管结构或不可拉伸柔性袋的形式，并且附接到壳体，以便不妨碍用于引入输注物的入口。在可变容积室附接到壳体的附近设置充液流体流动路径（31）。响应于可变体积腔室相对于壳体中的输注体积的膨胀，通过导管从装置输送输注液。提供单独的推注注射口（38），其允许将输注物直接安全地导入导管中并且覆盖受控的压力驱动输送。轻便的外壳可以包括一体形成的针止动件（32和34）和缝线紧固环（36）。

56. 发明申请

US20060122562A1 Controlled-volume infusion device 失效
公开(公告)号：US20060122562A1
公开(公告)日：2006-06-08
申请号：US11283091
申请日：2005-11-18
申请人： Stanley Needle , Andrew Lamborne
发明人： Stanley Needle , Andrew Lamborne
IPC分类号： A61M5/178
CPC分类号： A61M5/1454 , A61M5/14216 , A61M5/14586 , A61M5/16877 , A61M5/31511
摘要： An infusion device capable of administering liquid medication at a continuous flow rate, and upon user demand delivers a controlled volume dosage of liquid medication at a higher dosage flow rate. The dosage reservoir remains empty until the user actuates it by selectively and temporarily removing the pressure source, such as a spring. During actuation, fluid rapidly flows from the medication reservoir to fill the dosage reservoir. After actuation, the pressure source exerts a higher pressure on the dosage reservoir than the medication reservoir pressure, which results in a temporary higher bolus flow rate. Thus, two distinct flow rates are achieved with one flow restrictor element.

57. 发明申请

US20050177137A1 Administering device with temperature sensor 审中-公开
标题翻译：管理温度传感器
公开(公告)号：US20050177137A1
公开(公告)日：2005-08-11
申请号：US11067601
申请日：2005-02-25
申请人： Urs Kipfer
发明人： Urs Kipfer
IPC分类号： A61M5/00 , A61M1/36 , A61M5/142 , A61M5/145 , A61M5/168 , A61M37/00 , A61K9/22
CPC分类号： A61M5/16831 , A61M5/14244 , A61M5/1452 , A61M5/14586 , A61M2205/15 , A61M2205/18 , A61M2205/3368 , A61M2205/3372
摘要： A device for administering a fluid product, including a container for the fluid product, an apparatus for dispensing the fluid product from the container, a metering apparatus for adjusting a product dose, and at least one temperature sensor disposed inside the container or near the fluid product. The present invention also encompasses a method for controlling the administration of a fluid product, wherein a metered quantity of a product dose, which is to be administered, is adjusted in accordance with the temperature of the fluid product and/or the temperature of the surroundings of the fluid product.
摘要翻译：一种用于施用流体产品的装置，包括用于流体产品的容器，用于从容器分配流体产品的装置，用于调节产品剂量的计量装置，以及设置在容器内或流体附近的至少一个温度传感器产品。本发明还包括一种用于控制流体产品的给药的方法，其中根据流体产品的温度和/或周围环境的温度来调节计量量的待施用的产品剂量的流体产品。

58. 发明授权

US06902544B2 Troubleshooting accelerator system for implantable drug delivery pumps 有权
标题翻译：疑难解答可植入药物输送泵的加速器系统
公开(公告)号：US06902544B2
公开(公告)日：2005-06-07
申请号：US10348812
申请日：2003-01-22
申请人： Lev Ludin , Brooke Mastrorio , Tim Beardsley
发明人： Lev Ludin , Brooke Mastrorio , Tim Beardsley
IPC分类号： A61K9/22 , A61M5/142 , A61M5/145 , A61M5/168 , A61M39/22 , A61M31/00
CPC分类号： A61M5/14276 , A61M5/14586 , A61M5/16827 , A61M5/16831 , A61M5/16881 , A61M2205/15
摘要： An implantable pump and methods for detecting leaks in an implantable pump are provided. In one embodiment, the implantable drug pump includes a housing having at least one inlet port and an outlet port formed therein. The outlet port is adapted to communicate with a catheter for delivering fluid to a patient's body, and the inlet port(s) are effective to deliver fluid into the housing. The housing further includes at least one reservoir disposed therein and effective to contain a fluid. In use, the pump preferably includes a fluid having one or more drugs disposed in at least one of the reservoirs, and a radiolucent fluid disposed in one of the reservoirs. A user programmable control mechanism is coupled to the drug pump and is effective to selectively control movement of the valves between the open and closed positions.
摘要翻译：提供了可植入泵和用于检测可植入泵中的泄漏的方法。在一个实施例中，可植入药物泵包括具有形成在其中的至少一个入口端口和出口端口的壳体。出口适于与用于将流体输送到患者身体的导管连通，并且入口端口有效地将流体输送到壳体中。壳体还包括设置在其中的至少一个储存器并且有效地容纳流体。在使用中，泵优选地包括具有设置在至少一个储存器中的一种或多种药物的流体和设置在一个储存器中的不透射线的流体。用户可编程控制机构联接到药物泵，并且有效地选择性地控制阀在打开位置和关闭位置之间的运动。

59. 发明授权

US06652510B2 Implantable infusion device and reservoir for same 有权
标题翻译：植入式输液装置和储罐相同
公开(公告)号：US06652510B2
公开(公告)日：2003-11-25
申请号：US10033377
申请日：2001-12-26
申请人： Peter C. Lord , William A. Brandt , Scott R. Gibson
发明人： Peter C. Lord , William A. Brandt , Scott R. Gibson
IPC分类号： A61K922
CPC分类号： A61M5/14276 , A61M5/14224 , A61M5/14244 , A61M5/14586 , Y10S128/12
摘要： An implantable infusion device includes of a disc-shaped housing that is made from a biocompatible material and contains a reservoir. The reservoir defines a chamber that contains at least one flexible diaphragm. A ring is provided in alignment with the peripheral edge of each diaphragm. The ring has a central opening that is aligned with the convolution and central portion of each diaphragm, to allow the diaphragm to flex within the ring. In this manner, the volume on one side of each diaphragm may be varied to correspond to a varying volume of infusion medium. Similarly, the volume within the reservoir chamber on the other side of the diaphragms is varied as the diaphragms flex, to correspond to the expansion and contraction of a propellant medium within the reservoir.
摘要翻译：植入式输注装置包括由生物相容性材料制成且包含储存器的圆盘形壳体。储存器限定包含至少一个柔性隔膜的室。提供与每个隔膜的周缘对准的环。环具有与每个隔膜的卷积和中心部分对准的中心开口，以允许隔膜在环内弯曲。以这种方式，每个隔膜的一侧上的体积可以变化以对应于输注介质的变化体积。类似地，当膜片弯曲时，膜片另一侧的储存室内的体积随着储存器内的推进剂介质的膨胀和收缩而变化。

60. 发明申请

US20030078550A1 Implantable pump catheter access port denial device 失效
标题翻译：植入式泵导管进口端口拒绝装置
公开(公告)号：US20030078550A1
公开(公告)日：2003-04-24
申请号：US10014634
申请日：2001-10-22
发明人： Shobha Devi Williamson , Chris C. Christiansen , Laura Sue McWilliam
IPC分类号： A61M031/00
CPC分类号： A61M5/14276 , A61M5/14586 , A61M39/0208 , A61M2209/045 , Y10S128/12
摘要： A device and method configured for placement into the catheter access port to prevent insertion of a needle into the catheter access port. The device is comprised of a prong to engage the housing and lock itself in the catheter access port, an annular surface having geometry complimentary to the catheter access port to seal the denial device, and a face configured to deny needle access to the catheter access port. The device is also self sealing to substantial prevent deposition between itself and the catheter access port, is configured to be inserted without the need for tools, and is manufactured from biocompatible material. The method for inserting this device consists of aligning the device with the catheter access port, inserting the device, confirming it is in place, and sealing it into the catheter access port.
摘要翻译：一种被配置为放置在导管进入口中以防止将针插入导管进入端口中的装置和方法。该装置包括插脚以使壳体接合并将其自身锁定在导管进入端口中，具有与导管进入端口互补的几何形状以密封拒绝装置的环形表面，以及被配置为拒绝针导入导管进入端口的面。该装置也是自密封的，以显着地防止其自身与导管进入口之间的沉积，被构造为插入而不需要工具，并由生物相容性材料制成。用于插入该装置的方法包括将装置与导管进入口对准，插入装置，确认其就位，并将其密封到导管进入口中。

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