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1. 发明授权

US06652510B2 Implantable infusion device and reservoir for same 有权
标题翻译：植入式输液装置和储罐相同
公开(公告)号：US06652510B2
公开(公告)日：2003-11-25
申请号：US10033377
申请日：2001-12-26
申请人： Peter C. Lord , William A. Brandt , Scott R. Gibson
发明人： Peter C. Lord , William A. Brandt , Scott R. Gibson
IPC分类号： A61K922
CPC分类号： A61M5/14276 , A61M5/14224 , A61M5/14244 , A61M5/14586 , Y10S128/12
摘要： An implantable infusion device includes of a disc-shaped housing that is made from a biocompatible material and contains a reservoir. The reservoir defines a chamber that contains at least one flexible diaphragm. A ring is provided in alignment with the peripheral edge of each diaphragm. The ring has a central opening that is aligned with the convolution and central portion of each diaphragm, to allow the diaphragm to flex within the ring. In this manner, the volume on one side of each diaphragm may be varied to correspond to a varying volume of infusion medium. Similarly, the volume within the reservoir chamber on the other side of the diaphragms is varied as the diaphragms flex, to correspond to the expansion and contraction of a propellant medium within the reservoir.
摘要翻译：植入式输注装置包括由生物相容性材料制成且包含储存器的圆盘形壳体。储存器限定包含至少一个柔性隔膜的室。提供与每个隔膜的周缘对准的环。环具有与每个隔膜的卷积和中心部分对准的中心开口，以允许隔膜在环内弯曲。以这种方式，每个隔膜的一侧上的体积可以变化以对应于输注介质的变化体积。类似地，当膜片弯曲时，膜片另一侧的储存室内的体积随着储存器内的推进剂介质的膨胀和收缩而变化。

2. 发明授权

US08002747B2 Implantable infusion device with multiple controllable fluid outlets 有权
标题翻译：具有多个可控流体出口的植入式输液装置
公开(公告)号：US08002747B2
公开(公告)日：2011-08-23
申请号：US11420641
申请日：2006-05-26
申请人： Peter C. Lord , Stephen D. Das , Scott R. Gibson
发明人： Peter C. Lord , Stephen D. Das , Scott R. Gibson
IPC分类号： A61M37/00
CPC分类号： A61M5/14276 , A61M5/16827
摘要： An implantable infusion system includes at least two controllable fluid transfer devices that may be used to transfer different fluid flows to the same or different body sites.
摘要翻译：可植入输注系统包括至少两个可控流体输送装置，其可用于将不同流体流转移到相同或不同的身体部位。

3. 发明授权

US08070745B2 Medication infusion device using negatively biased ambient pressure medication chamber 有权
标题翻译：使用负偏压环境压力药房的药物输液装置
公开(公告)号：US08070745B2
公开(公告)日：2011-12-06
申请号：US11294973
申请日：2005-12-06
申请人： Scott R. Gibson , Peter C. Lord
发明人： Scott R. Gibson , Peter C. Lord
IPC分类号： A61K9/22 , A61M37/00 , A61M1/00
CPC分类号： A61M5/14276 , A61M5/14586 , A61M2005/14264 , A61M2205/0266
摘要： A method and apparatus for infusing medication into a patient's body using a medication chamber referenced to ambient pressure. The apparatus includes a medication chamber enclosed by a peripheral wall which includes a movable portion configured to transfer exterior ambient pressure into the chamber. Means are provided for exerting a negative bias force acting on the movable portion in a direction opposed to the ambient pressure force. Thus, the resultant pressure in the chamber will be negative with respect to ambient pressure, reducing the risk that the chamber can be overpressurized and produce an unintended medication discharge.
摘要翻译：使用以环境压力为基准的药物室将药物注入患者体内的方法和装置。该装置包括由周壁包围的药物室，其包括构造成将外部环境压力转移到室中的可移动部分。提供了用于在与环境压力相反的方向上施加作用在可动部分上的负偏压力的装置。因此，室内的合成压力相对于环境压力将为负值，从而降低了腔室能够被过度加压并产生非预期的药物排出的风险。

4. 发明申请

US20090149810A1 Implantable Infusion Devices Including Apparatus For Confirming Fluid Flow And Systems, Apparatus And Methods Associated With Same 有权
标题翻译：包括用于确认流体流动和系统的装置的植入式输液装置，与之相关的装置和方法
公开(公告)号：US20090149810A1
公开(公告)日：2009-06-11
申请号：US12329459
申请日：2008-12-05
申请人： Lawrence Scott Ring , Peter C. Lord , Scott R. Gibson , Sam W. Bowman , Brian M. Shelton
发明人： Lawrence Scott Ring , Peter C. Lord , Scott R. Gibson , Sam W. Bowman , Brian M. Shelton
IPC分类号： A61M5/172 , A61M5/142 , G01F1/00
CPC分类号： A61M5/16831 , A61M5/14276 , A61M5/16854 , A61M5/16886 , A61M2005/16863 , A61M2205/0244 , A61M2205/0294 , A61M2205/3331 , A61M2205/3334 , A61M2205/3523 , G01F1/28
摘要： Implantable infusion apparatus, systems and methods that involve the use of a sensor that is associated with the catheter outlet.
摘要翻译：涉及使用与导管出口相关联的传感器的植入式输注设备，系统和方法。

5. 发明授权

US06537268B1 Medical infusion device with a source of controlled compliance 有权
标题翻译：具有受控依从性的输液装置
公开(公告)号：US06537268B1
公开(公告)日：2003-03-25
申请号：US09335936
申请日：1999-06-18
申请人： Scott R. Gibson , Peter C. Lord , Eric M. Lorenzen , Susan M. McConnell , John F. Gray , Robert W. Bosley
发明人： Scott R. Gibson , Peter C. Lord , Eric M. Lorenzen , Susan M. McConnell , John F. Gray , Robert W. Bosley
IPC分类号： A61K922
CPC分类号： A61M5/14276 , A61M2209/045
摘要： Embodiments of medical infusion pumps are provided that include structural elements for providing sources of compliance within a fluid path within the pump. Some preferred embodiments provide implantable infusion pumps with compliance positioned between an exit port of a pumping mechanism and an outlet (e.g. an opening in a catheter) of the infusion pump. Other embodiments provide compliance in fluid path in proximity to entrance port of the pumping mechanism. Insertion of compliance in a flow path that is down stream of the pumping mechanism may aid in minimizing negative effects associated with attempting to force fluid through a restricted flow path that is further down-stream, such as that offered by a catheter or other outlet component. Insertion of compliance before the pumping mechanism may aid in reducing negative effects associated with an up stream restricted flow path, such as that which might be offered by a rigid filter located between the reservoir and the pumping mechanism. Several structural components, assemblies, or configurations may be used as sources of compliance. For example, compressible structures (e.g. pillows, drums) are used within a side port of the infusion pump. The compressible structures may quickly distort to accommodate for a large impulse of fluid into the flow path that can not otherwise be readily dealt with. The compression, in turn, results in a restoring force being exerted that returns the structure substantially to its original volume so as to slowly force fluid from the flow path.
摘要翻译：提供了医用输液泵的实施例，其包括用于在泵内的流体路径内提供顺应性源的结构元件。一些优选的实施方案提供了植入式输注泵，其具有定位在泵送机构的出口与输液泵的出口（例如导管中的开口）之间的顺应性。其他实施例提供了靠近泵送机构的入口的流体路径中的顺应性。在泵送机构下游的流动路径中插入顺应性可以有助于最小化与试图迫使流体进一步向下流动的受限流动路径相关联的负面影响，例如由导管或其他出口部件。在泵送机构之前插入顺应性可以有助于减少与向上流限制的流动路径相关联的负面影响，例如位于储存器和泵送机构之间的刚性过滤器可能提供的负面影响。可以使用几种结构组件，组件或配置作为遵守来源。例如，在输注泵的侧端口内使用可压缩结构（例如，枕头，鼓）。可压缩结构可以快速变形以适应大流量的流体进入流动路径，否则不能容易地处理。压缩又导致施加的恢复力，使得结构基本上返回到其原始体积，以便缓慢地迫使来自流动路径的流体。

6. 发明申请

US20110270233A1 Implantable Infusion Device With Multiple Controllable Fluid Outlets 有权
标题翻译：具有多个可控流体出口的植入式输液装置
公开(公告)号：US20110270233A1
公开(公告)日：2011-11-03
申请号：US13182412
申请日：2011-07-13
申请人： Peter C. Lord , Stephen D. Das , Scott R. Gibson
发明人： Peter C. Lord , Stephen D. Das , Scott R. Gibson
IPC分类号： A61M5/142
CPC分类号： A61M5/14276 , A61M5/16827
摘要： An implantable infusion system includes at least two controllable fluid transfer devices that may be used to transfer different fluid flows to the same or different body sites.
摘要翻译：可植入输注系统包括至少两个可控流体输送装置，其可用于将不同流体流转移到相同或不同的身体部位。

7. 发明授权

US08932253B2 Medication infusion device using negatively biased ambient pressure medication chamber 有权
标题翻译：使用负偏压环境压力药房的药物输液装置
公开(公告)号：US08932253B2
公开(公告)日：2015-01-13
申请号：US13287651
申请日：2011-11-02
申请人： Scott R. Gibson , Peter C. Lord
发明人： Scott R. Gibson , Peter C. Lord
IPC分类号： A61M37/00 , A61M31/00 , A61K9/22 , A61M5/142 , A61M5/145
CPC分类号： A61M5/14276 , A61M5/14586 , A61M2005/14264 , A61M2205/0266
摘要： A method and apparatus for infusing medication into a patient's body using a medication chamber referenced to ambient pressure. The apparatus includes a medication chamber enclosed by a peripheral wall which includes a movable portion configured to transfer exterior ambient pressure into the chamber. Means are provided for exerting a negative bias force acting on the movable portion in a direction opposed to the ambient pressure force. Thus, the resultant pressure in the chamber will be negative with respect to ambient pressure, reducing the risk that the chamber can be overpressurized and produce an unintended medication discharge.
摘要翻译：使用以环境压力为基准的药物室将药物注入患者体内的方法和装置。该装置包括由周壁包围的药物室，其包括构造成将外部环境压力转移到室中的可移动部分。提供了用于在与环境压力相反的方向上施加作用在可动部分上的负偏压力的装置。因此，室内的合成压力相对于环境压力将为负值，从而降低了腔室能够被过度加压并产生非预期的药物排出的风险。

8. 发明授权

US08808243B2 Implantable infusion device with multiple controllable fluid outlets 有权
标题翻译：具有多个可控流体出口的植入式输液装置
公开(公告)号：US08808243B2
公开(公告)日：2014-08-19
申请号：US13182412
申请日：2011-07-13
申请人： Peter C. Lord , Stephen D. Das , Scott R. Gibson
发明人： Peter C. Lord , Stephen D. Das , Scott R. Gibson
IPC分类号： A61M37/00 , A61M5/142 , A61M5/168
CPC分类号： A61M5/14276 , A61M5/16827
摘要： An implantable infusion system includes at least two controllable fluid transfer devices that may be used to transfer different fluid flows to the same or different body sites.
摘要翻译：可植入输注系统包括至少两个可控流体输送装置，其可用于将不同流体流转移到相同或不同的身体部位。

9. 发明授权

US08323268B2 Implantable infusion devices including apparatus for confirming fluid flow and systems, apparatus and methods associated with same 有权
标题翻译：植入式输液装置，包括用于确认流体流动的装置和与之相关的系统，装置和方法
公开(公告)号：US08323268B2
公开(公告)日：2012-12-04
申请号：US12329459
申请日：2008-12-05
申请人： Lawrence Scott Ring , Peter C. Lord , Scott R. Gibson , Sam W. Bowman , Brian M. Shelton
发明人： Lawrence Scott Ring , Peter C. Lord , Scott R. Gibson , Sam W. Bowman , Brian M. Shelton
IPC分类号： A61L9/22 , A61M31/00
CPC分类号： A61M5/16831 , A61M5/14276 , A61M5/16854 , A61M5/16886 , A61M2005/16863 , A61M2205/0244 , A61M2205/0294 , A61M2205/3331 , A61M2205/3334 , A61M2205/3523 , G01F1/28
摘要： Implantable infusion apparatus, systems and methods that involve the use of a sensor that is associated with the catheter outlet.
摘要翻译：涉及使用与导管出口相关联的传感器的植入式输注设备，系统和方法。

10. 发明申请

US20120130353A1 Medication infusion device using negatively biased ambient pressure medication chamber 有权
标题翻译：使用负偏压环境压力药房的药物输液装置
公开(公告)号：US20120130353A1
公开(公告)日：2012-05-24
申请号：US13287651
申请日：2011-11-02
申请人： Scott R. Gibson , Peter C. Lord
发明人： Scott R. Gibson , Peter C. Lord
IPC分类号： A61M5/142
CPC分类号： A61M5/14276 , A61M5/14586 , A61M2005/14264 , A61M2205/0266
摘要： A method and apparatus for infusing medication into a patient's body using a medication chamber referenced to ambient pressure. The apparatus includes a medication chamber enclosed by a peripheral wall which includes a movable portion configured to transfer exterior ambient pressure into the chamber. Means are provided for exerting a negative bias force acting on the movable portion in a direction opposed to the ambient pressure force. Thus, the resultant pressure in the chamber will be negative with respect to ambient pressure, reducing the risk that the chamber can be overpressurized and produce an unintended medication discharge.
摘要翻译：使用以环境压力为基准的药物室将药物注入患者体内的方法和装置。该装置包括由周壁包围的药物室，其包括构造成将外部环境压力转移到室中的可移动部分。提供了用于在与环境压力相反的方向上施加作用在可动部分上的负偏压力的装置。因此，室内的合成压力相对于环境压力将为负值，从而降低了腔室能够被过度加压并产生非预期的药物排出的风险。

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