专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

51. 发明授权

US07957800B2 Preferred ADI/R: a permanent pacing mode to eliminate ventricular pacing while maintaining backup support 有权
标题翻译：优选的ADI / R：一种永久起搏模式，可在维持备用支持的同时消除心室起搏
公开(公告)号：US07957800B2
公开(公告)日：2011-06-07
申请号：US11550035
申请日：2006-10-17
申请人： David A. Casavant , Paul Belk , Thomas J. Mullen , John C. Stroebel
发明人： David A. Casavant , Paul Belk , Thomas J. Mullen , John C. Stroebel
IPC分类号： A61N1/368
CPC分类号： A61N1/368 , A61N1/3682 , A61N1/3688
摘要： A preferred atrial-based pacing method and apparatus is provided using an intelligent cardiac pacing system to having the ability to continue atrial-based pacing as long as relatively reliable AV conduction is present. In the event that such relatively reliable AV conduction is not present, mode switching to a DDD/R or a DDI/R pacing mode while continually biased to mode switch back to atrial-based pacing. The standard or relatively reliable AV conduction may be changed either automatically or manually. This increases pacing that utilizes natural AV conduction however possible so as to gain all the benefits of cardiac contractile properties resulting therefrom, while tolerating the occasional missed ventricular depolarization (i.e., non-conducted P-wave). In the event where relatively reliable AV conduction is not present, the pacing mode is switched to a DDD/R mode while detecting a return of the relatively reliable AV conduction (and resulting mode switch to preferred atrial based pacing).
摘要翻译：只要存在相对可靠的AV传导，使用智能心脏起搏系统提供优选的基于心房的起搏方法和装置，以具有继续心房起搏的能力。在不存在这种相对可靠的AV传导的情况下，模式切换到DDD / R或DDI / R起搏模式，同时不断偏向模式切换回基于心房的起搏。标准或相对可靠的AV传导可以自动或手动改变。这增加了使用自然AV传导的起搏，尽可能地获得心脏收缩性质的所有益处，同时容忍偶尔的心室去极化（即，未传导的P波）。在不存在相对可靠的AV导通的情况下，起搏模式被切换到DDD / R模式，同时检测到相对可靠的AV导通的返回（并且导致的模式切换到优选的心房起搏）。

52. 发明授权

US07869876B2 Method and apparatus for monitoring and optimizing atrial function 有权
标题翻译：监测和优化心房功能的方法和装置
公开(公告)号：US07869876B2
公开(公告)日：2011-01-11
申请号：US11245623
申请日：2005-10-07
申请人： Rajan Prakash , Edward Chinchoy , Thomas J. Mullen
发明人： Rajan Prakash , Edward Chinchoy , Thomas J. Mullen
IPC分类号： A61N1/368
CPC分类号： A61N1/368 , A61B5/0452 , A61B5/1107 , A61B2562/0219 , A61N1/3627 , A61N1/36542 , A61N1/3682
摘要： A method for use in an implantable medical device, comprising: sensing a signal corresponding to ventricular wall acceleration; and determining a metric of atrial function using the ventricular wall acceleration signal. The method includes sensing the ventricular wall acceleration signal during at least during a sensing window corresponding to a ventricular filling phase.
摘要翻译：一种用于可植入医疗装置的方法，包括：感测对应于心室壁加速度的信号; 并使用心室壁加速度信号确定心房功能的度量。该方法包括在至少在对应于心室填充阶段的感测窗口期间感测心室壁加速度信号。

53. 发明申请

US20100087882A1 VENTRICULAR EVENT FILTERING FOR AN IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：可植入医疗器械的静脉内过滤
公开(公告)号：US20100087882A1
公开(公告)日：2010-04-08
申请号：US12574585
申请日：2009-10-06
申请人： Robert A. Betzold , David A. Casavant , Paul A. Belk , Thomas J. Mullen , John C. Stroebel , Steven R. Hornberger , Todd J. Sheldon , Douglas A. Peterson
发明人： Robert A. Betzold , David A. Casavant , Paul A. Belk , Thomas J. Mullen , John C. Stroebel , Steven R. Hornberger , Todd J. Sheldon , Douglas A. Peterson
IPC分类号： A61N1/368 , A61N1/39
CPC分类号： A61N1/368 , A61N1/3688 , A61N1/3702
摘要： Pacing parameters are provided to address cross talk and intrinsic ventricular events occurring within a predefined blanking period following an atrial event. The parameters are used in conjunction with protocol for minimizing or reducing ventricular pacing, wherein ignoring intrinsic ventricular events during the blanking period might otherwise affect the performance of the protocol.
摘要翻译：提供起搏参数以解决心房事件发生后的预定义消隐期间发生的串扰和内在心室事件。这些参数与协议一起使用以最小化或减少心室起搏，其中在消隐期间忽略内部心室事件可能会影响该方案的性能。

54. 发明授权

US07672715B2 Method and apparatus for determining excitation-physiologic response delays 有权
标题翻译：用于确定激发 - 生理反应延迟的方法和装置
公开(公告)号：US07672715B2
公开(公告)日：2010-03-02
申请号：US11343753
申请日：2006-01-31
申请人： Rajan Prakash , Edward Chinchoy , Thomas J. Mullen
发明人： Rajan Prakash , Edward Chinchoy , Thomas J. Mullen
IPC分类号： A61B5/04
CPC分类号： A61N1/368 , A61N1/3627 , A61N1/36542 , A61N1/3682
摘要： An implantable medical device system and associated method are provided for measuring an excitation-physiological response delay. The method includes sensing a first signal responsive to electrical activity in a first cardiac chamber, sensing a second signal responsive to a physiologic response to the electrical activity in the first cardiac chamber; and determining an excitation-physiologic response delay in response to the first signal and the second signal.
摘要翻译：提供了一种用于测量激发 - 生理反应延迟的可植入医疗装置系统和相关方法。所述方法包括响应于第一心室中的电活动来感测第一信号，感测响应于对第一心室中的电活动的生理反应的第二信号; 以及响应于所述第一信号和所述第二信号确定激发 - 生理响应延迟。

55. 发明申请

US20100023081A1 Comprehensive System for Detection of Coronary Syndrome, Cardiac Ischemia and Myocardial Infarction 审中-公开
标题翻译：冠状动脉综合征，心脏缺血和心肌梗死综合检测系统
公开(公告)号：US20100023081A1
公开(公告)日：2010-01-28
申请号：US12181247
申请日：2008-07-28
申请人： Sarah Anne Audet , James Kevin Carney , William J. Combs , Eduardo N. Warman , Edward Chinchoy , Thomas J. Mullen , Brian Bruce Lee , Qingshan (Sam) Ye
发明人： Sarah Anne Audet , James Kevin Carney , William J. Combs , Eduardo N. Warman , Edward Chinchoy , Thomas J. Mullen , Brian Bruce Lee , Qingshan (Sam) Ye
IPC分类号： A61N1/365
CPC分类号： A61B5/0452 , A61B5/0031 , A61B5/02028 , A61B5/02055 , A61B5/02405 , A61B5/08 , A61B5/11 , A61B5/14532 , A61B5/14539 , A61B5/7275 , A61B7/00 , A61N1/3627 , A61N1/36514
摘要： Heart-monitoring systems, apparatus, and methods adapted to detect CS, CI and/or MI. In one embodiment, a system comprising at least two first-tier sensors capable of measuring and converting into signals at least two aspects related to cardiac function, at least one second-tier sensor that is also a first-tier sensor, at least one signal processor capable of transmitting a first-tier and second-tier trigger signal when coronary syndrome, cardiac ischemia or myocardial infarction has been detected, at least one communication device capable of communicating, at least one control element adapted to produce a first-tier and second-tier trigger signal when at least one first-tier sensor exceeds its threshold signal level, to exclude the signal from the first-tier sensor that exceeded its threshold and lower at least one threshold of the at least one first-tier sensor is provided.
摘要翻译：适用于检测CS，CI和/或MI的心脏监测系统，装置和方法。在一个实施例中，一种系统包括至少两个第一层传感器，能够测量和转换成与心脏功能相关的至少两个方面的信号，至少一个第二层传感器，其也是第一层传感器，至少一个信号处理器能够在冠状动脉综合征，心脏缺血或心肌梗塞已经被检测时发送第一层和第二层触发信号，至少一个能够通信的通信设备，至少一个适于产生第一层和第二层的控制元件当至少一个第一层传感器超过其阈值信号电平时，将第一层传感器的信号排除超过其阈值并降低至少一个第一层传感器的至少一个阈值。

56. 发明申请

US20090234411A1 APPARATUS AND METHODS OF OPTIMIZING ATRIOVENTRICULAR PACING DELAY INTERVALS 有权
标题翻译：优化ATRIOVENTRICULAR PACING DELAY INTERVALS的装置和方法
公开(公告)号：US20090234411A1
公开(公告)日：2009-09-17
申请号：US12047876
申请日：2008-03-13
申请人： Aleksandre T. Sambelashvili , Thomas J. Mullen
发明人： Aleksandre T. Sambelashvili , Thomas J. Mullen
IPC分类号： A61N1/365
CPC分类号： A61N1/36585 , A61N1/3627 , A61N1/3682 , A61N1/3684 , A61N1/375 , A61N1/3752 , A61N1/3756
摘要： Provided herewith are methods and apparatus for optimizing an atrioventricular (AV) pacing delay interval based upon ECG-based optimization is calculated as a linear function of P-wave duration, sensed PR (intrinsic) interval, sensed or paced QRS duration and heart rate. Since the relationship among these parameters is linear, once the coefficients are solved (which can be any value, including null) with reference to a known optimized AV interval (AVopt) such as from an echocardiographic study, an AVopt value can be dynamically adjusted in an ambulatory subject. The various combinations of values can be loaded into a look up table or calculated automatically. And, since some of the parameters do not typically change much over time they can be determined acutely and fed into the equation while the other values can be measured frequently. The parameter values can be measured by an implantable medical device such as a dual- or triple-chamber pacemaker.
摘要翻译：提供了用于优化基于ECG的优化的房室（AV）起搏延迟间隔的方法和装置，其被计算为P波持续时间，感测的PR（固有）间隔，感测或节奏QRS持续时间和心率的线性函数。由于这些参数之间的关系是线性的，所以参考已知的优化AV间隔（AVopt）（例如来自超声心动图研究），一旦系数被解决（其可以是包括空值的任何值）可以动态调整AVopt值一个流动的主题。值的各种组合可以加载到查找表中或自动计算。并且，由于一些参数通常不会随着时间而变化很大，因此它们可以被急剧地确定并且被馈送到方程式中，而可以频繁地测量其它值。参数值可以通过诸如双室或三室起搏器的可植入医疗装置来测量。

57. 发明授权

US07587242B2 Preferred ADI/R: a permanent pacing mode to eliminate ventricular pacing while maintaining backup support 有权
标题翻译：优选的ADI / R：一种永久起搏模式，可在维持备用支持的同时消除心室起搏
公开(公告)号：US07587242B2
公开(公告)日：2009-09-08
申请号：US11427571
申请日：2006-06-29
申请人： David A. Casavant , Paul A. Belk , Thomas J. Mullen , John C. Stroebel
发明人： David A. Casavant , Paul A. Belk , Thomas J. Mullen , John C. Stroebel
IPC分类号： A61N1/365
CPC分类号： A61N1/368 , A61N1/3682 , A61N1/3688
摘要： A preferred atrial-based pacing method and apparatus is provided using an intelligent cardiac pacing system to having the ability to continue atrial-based pacing as long as relatively reliable AV conduction is present. In the event that such relatively reliable AV conduction is not present, mode switching to a DDD/R or a DDI/R pacing mode while continually biased to mode switch back to atrial-based pacing. The standard or relatively reliable AV conduction may be changed either automatically or manually. This increases pacing that utilizes natural AV conduction however possible so as to gain all the benefits of cardiac contractile properties resulting therefrom, while tolerating the occasional missed ventricular depolarization (i.e., non-conducted P-wave). In the event where relatively reliable AV conduction is not present, the pacing mode is switched to a DDD/R mode while detecting a return of the relatively reliable AV conduction (and resulting mode switch to preferred atrial based pacing).
摘要翻译：只要存在相对可靠的AV传导，使用智能心脏起搏系统提供优选的基于心房的起搏方法和装置，以具有继续心房起搏的能力。在不存在这种相对可靠的AV传导的情况下，模式切换到DDD / R或DDI / R起搏模式，同时不断偏向模式切换回基于心房的起搏。标准或相对可靠的AV传导可以自动或手动改变。这增加了使用自然AV传导的起搏，尽可能地获得心脏收缩性质的所有益处，同时容忍偶尔的心室去极化（即，未传导的P波）。在不存在相对可靠的AV导通的情况下，起搏模式被切换到DDD / R模式，同时检测到相对可靠的AV导通的返回（并且导致的模式切换到优选的心房起搏）。

58. 发明申请

US20080269823A1 Apparatus and Methods for Automatic Determination of a Fusion Pacing Pre-Excitation Interval 有权
标题翻译：自动确定融合起搏预激间隔的装置和方法
公开(公告)号：US20080269823A1
公开(公告)日：2008-10-30
申请号：US11742230
申请日：2007-04-30
申请人： John E. Burnes , Thomas J. Mullen , Aleksandra T. Sambelashvili
发明人： John E. Burnes , Thomas J. Mullen , Aleksandra T. Sambelashvili
IPC分类号： A61N1/365
CPC分类号： A61N1/3627 , A61N1/36542 , A61N1/36585 , A61N1/3682 , A61N1/3684
摘要： Automated adjustment of a pre-excitation interval (PEI) used to deliver hemodynamically efficient fusion pacing therapy.
摘要翻译：用于提供血液动力学有效的融合起搏治疗的预激发间隔（PEI）的自动调整。

59. 发明授权

US07181284B2 Apparatus and methods of energy efficient, atrial-based Bi-ventricular fusion-pacing 有权
标题翻译：节能，基于心房的双心室融合起搏的装置和方法
公开(公告)号：US07181284B2
公开(公告)日：2007-02-20
申请号：US10803570
申请日：2004-03-17
申请人： John E. Burnes , Thomas J. Mullen
发明人： John E. Burnes , Thomas J. Mullen
IPC分类号： A61N1/36
CPC分类号： A61N1/3627 , A61N1/3682 , A61N1/3684
摘要： The bi-ventricular implantable pulse generator described and depicted herein enables hemodynamic efficiencies for patients suffering from intraventricular conduction delays or conduction blockage. The pulse generator effectively overcomes such conduction delay or block (e.g., left bundle branch block, “LBBB,” or right bundle branch block, “RBBB”) by delivering a novel form of cardiac resynchronization therapy (CRT). Specifically, a single ventricular pre-excitation pacing stimulus is triggered from an atrial event (e.g., intrinsic or evoked depolarization). The triggering event may emanate from the right atrium (RA) or the left atrium (LA). A single ventricular pre-excitation pacing stimulus is delivered prior to the intrinsic depolarization of the other ventricle and thus promotes intraventricular electromechanical synchrony during CRT delivery.
摘要翻译：本文描述和描述的双心室可植入脉冲发生器能够对患有心室内传导延迟或传导阻塞的患者进行血液动力学效率。通过递送心脏再同步治疗（CRT）的新形式，脉冲发生器有效地克服了这种传导延迟或阻滞（例如左束支传导阻滞“LBBB”或右束支传导阻滞“RBBB”）。具体来说，从心房事件（例如内在或诱发的去极化）触发单个心室预激发起搏刺激。触发事件可能从右心房（RA）或左心房（LA）发出。在另一个心室的内在去极化之前输送单个心室预激励起搏刺激，从而在CRT输送期间促进脑室内机电同步。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式