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    • 53. 发明授权
    • Ultrasonograph
    • 超声波检查
    • US07278968B2
    • 2007-10-09
    • US10466630
    • 2002-02-06
    • Shin-ichiro UmemuraKen-ichi Kawabata
    • Shin-ichiro UmemuraKen-ichi Kawabata
    • A61B8/06
    • A61B8/481G01S15/895
    • An ultrasonograph is provided wherein the decrease of the density of the stabilized microbubble contrast agent in a desired body target area can be inhibited, radiating ultrasonic energy required for satisfactory signal-to-noise ratio and sufficient frame rate, where an ultrasonic probe transmits an ultrasonic pulse acquired by superimposing higher harmonics including a second harmonic of the fundamental onto the fundamental wave, such as a maximum positive pressure enhanced waveform or a maximum negative pressure enhanced waveform, or an acoustic pressure rise enhanced waveform or an acoustic pressure fall enhanced waveform.
    • 提供了一种超声波诊断仪,其中可以抑制所需身体目标区域中稳定的微泡造影剂的浓度的降低,辐射超声波能量以满足信噪比和足够的帧速率所需的超声波能量,其中超声波探头传输超声波 通过将包括基波的二次谐波的高次谐波(例如最大正压增强波形或最大负压增强波形)或声压上升增强波形或声压下降增强波形叠加在基波上而获得的脉冲。
    • 60. 发明授权
    • DNA analyzing method and device therefor
    • DNA分析方法及其设备
    • US6106777A
    • 2000-08-22
    • US552496
    • 1995-11-09
    • Takeshi FujitaShin-ichiro Umemura
    • Takeshi FujitaShin-ichiro Umemura
    • C12Q1/68G01N21/29
    • C12Q1/6816Y10S436/80Y10S436/807Y10S436/808Y10T436/143333
    • The object of the present invention is to provide a method capable of analyzing the presence or absence of a target DNA sequence, the level and sequence characteristics thereof at a high sensitivity, and a device therefor, wherein the overall process from pretreatment to the recovery of DNA information and the analysis thereof can be completed in a speedy fashion by the simple device structure and procedures.Therefore, by preparing a single-stranded DNA fragment of a target DNA region, detecting the change in the absorbance of the single-stranded DNA sample while changing the denaturing condition of the conformation of the single-stranded DNA fragment by a denaturing condition regulatory means, and analyzing the curve of the change in the absorbance over the modification in the denaturing condition, the sequence information of the single-stranded DNA, namely the target DNA, can be generated in a rapid and simple manner.
    • 本发明的目的是提供能够以高灵敏度分析靶DNA序列的存在或不存在的水平和序列特征的方法及其装置,其中从预处理到恢复的整个过程 DNA信息及其分析可以通过简单的装置结构和程序以快速的方式完成。 因此,通过制备靶DNA区域的单链DNA片段,通过变性条件调节方法,在改变单链DNA片段构象的变性条件的同时检测单链DNA样品的吸光度变化 ,并且在变性条件下分析改性后的吸光度变化曲线,可以快速且简单地生成单链DNA(即目标DNA)的序列信息。