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1. 发明授权

US07943231B2 Organism simulative phantom 有权
标题翻译：有机体模拟幻影
公开(公告)号：US07943231B2
公开(公告)日：2011-05-17
申请号：US11596044
申请日：2004-12-13
申请人： Ken-ichi Kawabata
发明人： Ken-ichi Kawabata
IPC分类号： B32B7/02
CPC分类号： A61B8/485 , A61B8/00 , A61B8/587 , Y10T428/24983
摘要： Provided is a tissue mimicking phantom technology capable of controlling an ultrasonic echo intensity and hardness and offering excellent stability. A tissue mimicking phantom includes a first portion and a second portion which is incorporated in the first portion and whose hardness and/or ultrasonic echo intensity is different from that of the first portion. The first portion and second portion are gel structures that are formed with a covalent bond of macromolecular strands or a chemical bond that is as strong as the covalent bond. The gel structure has a solid scatterer (for example, metal-oxide microparticles) dispersed therein. The first portion and second portion exhibit mutually different hardness levels and ultrasonic echo intensities.
摘要翻译：提供了能够控制超声回波强度和硬度并提供优异稳定性的组织模拟幻影技术。组织模拟体模包括第一部分和第二部分，其被结合在第一部分中，并且其硬度和/或超声回波强度不同于第一部分。第一部分和第二部分是由大分子链的共价键或与共价键一样强的化学键形成的凝胶结构。凝胶结构中分散有固体散射体（例如金属氧化物微粒）。第一部分和第二部分显示相互不同的硬度水平和超声回波强度。

2. 发明授权

US07780598B2 Sonodynamic treatment apparatus and method of controlling the same 有权
标题翻译：超声治疗装置及其控制方法
公开(公告)号：US07780598B2
公开(公告)日：2010-08-24
申请号：US11476866
申请日：2006-06-29
申请人： Nami Sugita , Ken-ichi Kawabata , Takashi Azuma , Shin-ichiro Umemura
发明人： Nami Sugita , Ken-ichi Kawabata , Takashi Azuma , Shin-ichiro Umemura
IPC分类号： A61B8/00
CPC分类号： A61B8/00 , A61M37/0092 , A61N7/00
摘要： In a sonodynamic treatment apparatus including: a first ultrasound radiating unit for radiating diagnostic ultrasound; a second ultrasound radiating unit for radiating treatment ultrasound; an echo detection unit for detecting an ultrasound echo; a diagnostic controller for radiating the diagnostic ultrasound with the first ultrasound radiating unit and detecting the ultrasound echo corresponding the diagnostic ultrasound; an echographic controller for processing an echographic image on the basis of the detected ultrasound echo; and a treatment controller for radiating the treatment ultrasound with the second ultrasound radiating unit, radiation of the treatment ultrasound with the second ultrasound radiating unit is controlled to have a predetermined exposure duration and a predetermined pause duration of the treatment ultrasound, and the echographic image is generated on the basis of the ultrasound echo during the pause duration of the treatment ultrasound exposure with the diagnostic image generator. The treatment ultrasound may be weakened after detection of a bubble generated by the treatment ultrasound.
摘要翻译：一种声动治疗装置，包括：用于放射诊断超声的第一超声波辐射单元; 用于放射治疗超声波的第二超声波辐射单元; 用于检测超声回波的回波检测单元; 诊断控制器，用于利用所述第一超声波辐射单元辐射所述诊断超声波，并且检测对应于所述诊断超声的超声回波; 基于检测到的超声回波来处理回波图像的回波记录控制器; 以及处理控制器，用于利用所述第二超声波辐射单元照射所述处理超声波，将所述处理超声波与所述第二超声波辐射单元的放射线控制为具有预定的曝光持续时间和所述治疗超声波的预定暂停持续时间，并且所述回波图像为在诊断图像生成器的处理超声波曝光的暂停时间期间，基于超声回波生成。检测到由治疗超声波产生的气泡后，治疗超声可能会减弱。

3. 发明申请

US20080261009A1 Organism Simulative Phantom 有权
标题翻译：有机体模拟幻影
公开(公告)号：US20080261009A1
公开(公告)日：2008-10-23
申请号：US11596044
申请日：2004-12-13
申请人： Ken-ichi Kawabata
发明人： Ken-ichi Kawabata
IPC分类号： B32B7/02 , B29C43/00
CPC分类号： A61B8/485 , A61B8/00 , A61B8/587 , Y10T428/24983
摘要： Provided is a tissue mimicking phantom technology capable of controlling an ultrasonic echo intensity and hardness and offering excellent stability. A tissue mimicking phantom includes a first portion and a second portion which is incorporated in the first portion and whose hardness and/or ultrasonic echo intensity is different from that of the first portion. The first portion and second portion are gel structures that are formed with a covalent bond of macromolecular strands or a chemical bond that is as strong as the covalent bond. The gel structure has a solid scatterer (for example, metal-oxide microparticles) dispersed therein. The first portion and second portion exhibit mutually different hardness levels and ultrasonic echo intensities.
摘要翻译：提供了能够控制超声回波强度和硬度并提供优异稳定性的组织模拟幻影技术。组织模拟体模包括第一部分和第二部分，其被结合在第一部分中，并且其硬度和/或超声回波强度不同于第一部分。第一部分和第二部分是由大分子链的共价键或与共价键一样强的化学键形成的凝胶结构。凝胶结构中分散有固体散射体（例如金属氧化物微粒）。第一部分和第二部分显示相互不同的硬度水平和超声回波强度。

4. 发明申请

US20080013593A1 Phantom 有权
标题翻译：幻影
公开(公告)号：US20080013593A1
公开(公告)日：2008-01-17
申请号：US11812769
申请日：2007-06-21
申请人： Ken-ichi Kawabata
发明人： Ken-ichi Kawabata
IPC分类号： G01N25/02 , G09B23/00 , G09B23/28
CPC分类号： G09B23/286 , G09B23/30
摘要： This invention provides an ultrasonic phantom that can respond to different ultrasonic intensities. Such ultrasonic phantom comprises a gel comprising a low-boiling compound in the form of droplets sealed therein. The invention also provides an assay technique using such phantom. This invention enables regulation of components of droplets, droplet size, and the ultrasonic intensity at which droplets are vaporized upon mixing of droplets with different sizes. This enables visualization of whether or not ultrasound beams that exceed relevant different ultrasonic intensities have been applied.
摘要翻译：本发明提供了可响应不同超声波强度的超声波模型。这样的超声波体模包括一种凝胶，其包含密封在其中的液滴形式的低沸点化合物。本发明还提供了使用这种体模的测定技术。本发明能够调节液滴的组分，液滴尺寸和液滴在混合具有不同尺寸的液滴时蒸发的超声波强度。这使得可以观察到是否已经应用了超过相关不同超声波强度的超声波束。

5. 发明授权

US08011826B2 Phantom 有权
标题翻译：幻影
公开(公告)号：US08011826B2
公开(公告)日：2011-09-06
申请号：US11812769
申请日：2007-06-21
申请人： Ken-ichi Kawabata
发明人： Ken-ichi Kawabata
IPC分类号： G01N25/00 , G09B23/00
CPC分类号： G09B23/286 , G09B23/30
摘要： This invention provides an ultrasonic phantom that can respond to different ultrasonic intensities. Such ultrasonic phantom comprises a gel comprising a low-boiling compound in the form of droplets sealed therein. The invention also provides an assay technique using such phantom. This invention enables regulation of components of droplets, droplet size, and the ultrasonic intensity at which droplets are vaporized upon mixing of droplets with different sizes. This enables visualization of whether or not ultrasound beams that exceed relevant different ultrasonic intensities have been applied.
摘要翻译：本发明提供了可响应不同超声波强度的超声波模型。这样的超声波体模包括一种凝胶，其包含密封在其中的液滴形式的低沸点化合物。本发明还提供了使用这种体模的测定技术。本发明能够调节液滴的组分，液滴尺寸和液滴在混合具有不同尺寸的液滴时蒸发的超声波强度。这使得可以观察到是否已经应用了超过相关不同超声波强度的超声波束。

6. 发明申请

US20070161897A1 Ultrasonic treatment equipment 失效
标题翻译：超声波处理设备
公开(公告)号：US20070161897A1
公开(公告)日：2007-07-12
申请号：US10557237
申请日：2004-05-18
申请人： Kazuaki Sasaki , Takashi Azuma , Ken-ichi Kawabata , Shin-ichiro Umemura , Takashi Okai , Tetsuya Ishikawa
发明人： Kazuaki Sasaki , Takashi Azuma , Ken-ichi Kawabata , Shin-ichiro Umemura , Takashi Okai , Tetsuya Ishikawa
IPC分类号： A61B8/00
CPC分类号： A61N7/02 , A61B8/06 , A61B8/13 , A61B2090/378
摘要： Ultrasonic treatment equipment is provided which repeats therapeutic ultrasound exposure while measuring a degree of vessel constriction on a therapeutic ultrasound exposure basis. This equipment includes: a therapeutic ultrasonic transducer 2 which exposes a blood vessel of an affected part to a focused therapeutic ultrasonic wave for a specified period of exposure time; an imaging ultrasonic probe 3 which images an ultrasound tomographic image of the affected part; a display unit 24 which displays the ultrasound tomographic image; means 21 for detecting a blood flow signal from a signal received by the imaging ultrasonic probe and determining the blood flow velocity of the blood vessels of the affected part; means 21 for calculating a rate of change in blood flow velocity during the exposure to the therapeutic ultrasonic wave or before and after the exposure to the therapeutic ultrasonic wave; and means 23 for controlling exposure conditions of the therapeutic ultrasonic wave on the basis of the rate of change in blood flow velocity, and thereby controlling the therapeutic ultrasonic transducer.
摘要翻译：提供超声波处理设备，其在治疗超声暴露基础上测量血管收缩程度时重复治疗性超声波暴露。该设备包括：治疗超声波换能器2，其将受影响部分的血管暴露于聚焦的治疗超声波达指定的曝光时间; 成像超声波探头3，其对受影响部分的超声断层图像进行成像; 显示单元24，其显示超声断层图像; 用于从由成像超声波探头接收的信号中检测血流信号并确定受影响部分的血管的血流速度的装置21; 用于计算暴露于治疗超声波期间或暴露于治疗超声波之前和之后的血流速度变化率的装置21; 以及基于血流速度变化率来控制治疗超声波的暴露条件的装置23，由此控制治疗用超声波换能器。

7. 发明授权

US07699779B2 Ultrasonic treatment equipment 失效
标题翻译：超声波处理设备
公开(公告)号：US07699779B2
公开(公告)日：2010-04-20
申请号：US10557237
申请日：2004-05-18
申请人： Kazuaki Sasaki , Takashi Azuma , Ken-ichi Kawabata , Shin-ichiro Umemura , Takashi Okai , Tetsuya Ishikawa
发明人： Kazuaki Sasaki , Takashi Azuma , Ken-ichi Kawabata , Shin-ichiro Umemura , Takashi Okai , Tetsuya Ishikawa
IPC分类号： A61B8/00
CPC分类号： A61N7/02 , A61B8/06 , A61B8/13 , A61B2090/378
摘要： Ultrasonic treatment equipment is provided which repeats therapeutic ultrasound exposure while measuring a degree of vessel constriction on a therapeutic ultrasound exposure basis. This equipment includes: a therapeutic ultrasonic transducer 2 which exposes a blood vessel of an affected part to a focused therapeutic ultrasonic wave for a specified period of exposure time; an imaging ultrasonic probe 3 which images an ultrasound tomographic image of the affected part; a display unit 24 which displays the ultrasound tomographic image; means 21 for detecting a blood flow signal from a signal received by the imaging ultrasonic probe and determining the blood flow velocity of the blood vessels of the affected part; means 21 for calculating a rate of change in blood flow velocity during the exposure to the therapeutic ultrasonic wave or before and after the exposure to the therapeutic ultrasonic wave; and means 23 for controlling exposure conditions of the therapeutic ultrasonic wave on the basis of the rate of change in blood flow velocity, and thereby controlling the therapeutic ultrasonic transducer.
摘要翻译：提供超声波处理设备，其在治疗超声暴露基础上测量血管收缩程度时重复治疗性超声波暴露。该设备包括：治疗超声波换能器2，其将受影响部分的血管暴露于聚焦的治疗超声波达指定的曝光时间; 成像超声波探头3，其对受影响部分的超声断层图像进行成像; 显示单元24，其显示超声断层图像; 用于从由成像超声波探头接收的信号中检测血流信号并确定受影响部分的血管的血流速度的装置21; 用于计算暴露于治疗超声波期间或暴露于治疗超声波之前和之后的血流速度变化率的装置21; 以及基于血流速度变化率来控制治疗超声波的暴露条件的装置23，由此控制治疗用超声波换能器。

8. 发明授权

US07278968B2 Ultrasonograph 有权
标题翻译：超声波检查
公开(公告)号：US07278968B2
公开(公告)日：2007-10-09
申请号：US10466630
申请日：2002-02-06
申请人： Shin-ichiro Umemura , Ken-ichi Kawabata
发明人： Shin-ichiro Umemura , Ken-ichi Kawabata
IPC分类号： A61B8/06
CPC分类号： A61B8/481 , G01S15/895
摘要： An ultrasonograph is provided wherein the decrease of the density of the stabilized microbubble contrast agent in a desired body target area can be inhibited, radiating ultrasonic energy required for satisfactory signal-to-noise ratio and sufficient frame rate, where an ultrasonic probe transmits an ultrasonic pulse acquired by superimposing higher harmonics including a second harmonic of the fundamental onto the fundamental wave, such as a maximum positive pressure enhanced waveform or a maximum negative pressure enhanced waveform, or an acoustic pressure rise enhanced waveform or an acoustic pressure fall enhanced waveform.
摘要翻译：提供了一种超声波诊断仪，其中可以抑制所需身体目标区域中稳定的微泡造影剂的浓度的降低，辐射超声波能量以满足信噪比和足够的帧速率所需的超声波能量，其中超声波探头传输超声波通过将包括基波的二次谐波的高次谐波（例如最大正压增强波形或最大负压增强波形）或声压上升增强波形或声压下降增强波形叠加在基波上而获得的脉冲。

9. 发明申请

US20070038099A1 Sonodynamic treatment apparatus and method of controlling the same 有权
标题翻译：超声治疗装置及其控制方法
公开(公告)号：US20070038099A1
公开(公告)日：2007-02-15
申请号：US11476866
申请日：2006-06-29
申请人： Nami Sugita , Ken-ichi Kawabata , Takashi Azuma , Shin-ichiro Umemura
发明人： Nami Sugita , Ken-ichi Kawabata , Takashi Azuma , Shin-ichiro Umemura
IPC分类号： A61B8/00
CPC分类号： A61B8/00 , A61M37/0092 , A61N7/00
摘要： In a sonodynamic treatment apparatus including: a first ultrasound radiating unit for radiating diagnostic ultrasound; a second ultrasound radiating unit for radiating treatment ultrasound; an echo detection unit for detecting an ultrasound echo; a diagnostic controller for radiating the diagnostic ultrasound with the first ultrasound radiating unit and detecting the ultrasound echo corresponding the diagnostic ultrasound; an echographic controller for processing an echographic image on the basis of the detected ultrasound echo; and a treatment controller for radiating the treatment ultrasound with the second ultrasound radiating unit, radiation of the treatment ultrasound with the second ultrasound radiating unit is controlled to have a predetermined exposure duration and a predetermined pause duration of the treatment ultrasound, and the echographic image is generated on the basis of the ultrasound echo during the pause duration of the treatment ultrasound exposure with the diagnostic image generator. The treatment ultrasound may be weakened after detection of a bubble generated by the treatment ultrasound.
摘要翻译：一种声动治疗装置，包括：用于放射诊断超声的第一超声波辐射单元; 用于放射治疗超声波的第二超声波辐射单元; 用于检测超声回波的回波检测单元; 诊断控制器，用于利用所述第一超声波辐射单元辐射所述诊断超声波，并且检测对应于所述诊断超声的超声回波; 基于检测到的超声回波来处理回波图像的回波记录控制器; 以及处理控制器，用于利用所述第二超声波辐射单元照射所述处理超声波，将所述处理超声波与所述第二超声波辐射单元的放射线控制为具有预定的曝光持续时间和所述治疗超声波的预定暂停持续时间，并且所述回波图像为在诊断图像生成器的处理超声波曝光的暂停时间期间，基于超声回波生成。检测到由治疗超声波产生的气泡后，治疗超声可能会减弱。

10. 发明授权

US08562531B2 Ultrasonic motion detecting device, and image producing device and ultrasonic therapeutic using the detecting device 失效
标题翻译：超声波运动检测装置，以及使用该检测装置的图像生成装置和超声治疗装置
公开(公告)号：US08562531B2
公开(公告)日：2013-10-22
申请号：US10583033
申请日：2004-11-16
申请人： Hideki Yoshikawa , Takashi Azuma , Shin-ichiro Umemura , Ken-ichi Kawabata
发明人： Hideki Yoshikawa , Takashi Azuma , Shin-ichiro Umemura , Ken-ichi Kawabata
IPC分类号： A61B8/00
CPC分类号： A61B8/08
摘要： There is provided a ultrasonic motion detecting device that detects a three-dimensional motion of an object. The ultrasonic motion detecting device, comprises first and second ultrasonic transducers 13 having piezoelectric elements arranged in an array, which transmit ultrasonic waves to an object and acquire reflection signals from the object, a motion detection unit 20 that extracts an estimation region which is used for estimating a motion of the object from the reflection signals that are acquired by the first and second ultrasonic transducers, and detects a three-dimensional motion within the estimation region, and an image display unit 19 that displays the three-dimensional motion within the estimation region, wherein ultrasonic wave scanning surfaces due to the first and second ultrasonic transducers cross over each other.
摘要翻译：提供了一种检测物体的三维运动的超声波运动检测装置。超声波运动检测装置包括具有排列成阵列的压电元件的第一和第二超声波换能器13，其将超声波向对象发送并从物体获取反射信号;运动检测单元20，其提取用于根据由第一和第二超声换能器获取的反射信号估计物体的运动，并且检测估计区域内的三维运动;以及图像显示单元19，其在估计区域内显示三维运动其中由于第一和第二超声波换能器引起的超声波扫描表面彼此交叉。

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