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51. 发明授权

US5260113A Translucent sign face constructions with minimum visibility seams 失效
标题翻译：半透明标志面结构，具有最小的可见性接缝
公开(公告)号：US5260113A
公开(公告)日：1993-11-09
申请号：US688648
申请日：1991-04-19
申请人： James A. Pontuti , Robert W. Warner , Richard F. Theissen , John A. Nielsen
发明人： James A. Pontuti , Robert W. Warner , Richard F. Theissen , John A. Nielsen
IPC分类号： B32B27/12 , B29C65/50 , G09F7/00 , G09F13/08 , B32B3/06 , B32B3/10
CPC分类号： G09F13/08 , B29C65/4815 , B29C65/5042 , B29C66/1142 , B29C66/43 , B29C66/721 , B29C66/7392 , G09F7/00 , B29C65/38 , B29C65/5021 , B29C65/5028 , B29C65/7847 , B29C66/71 , B29C66/91411 , B29C66/9241 , B29C66/929 , B29K2313/00 , Y10T428/19 , Y10T428/197 , Y10T428/20 , Y10T442/178 , Y10T442/198
摘要： A minimum visibility seam tape and method of joining at least two substrates with the tape. The substrates joined typically are sign faces or awnings comprising a composite of thermoplastics and a woven scrim. The seam tape is a woven or nonwoven scrim embedded in or coated with a thermoplastic polymer.

52. 发明授权

US5032209A Heat sealing of semicrystalline quasi-amorphous polymers 失效
标题翻译：半晶态无定形聚合物的热封
公开(公告)号：US5032209A
公开(公告)日：1991-07-16
申请号：US187024
申请日：1988-04-27
申请人： Madeline P. Shinbach , Robert W. Warner , Andrew J. Ouderkirk , Douglas S. Dunn
发明人： Madeline P. Shinbach , Robert W. Warner , Andrew J. Ouderkirk , Douglas S. Dunn
IPC分类号： C08J5/12 , G03F7/039
CPC分类号： C08J5/121 , G03F7/039
摘要： Semicrystalline polymers can have predetermined amounts of their surfaces rendered quasi-amorphous by irradiation. Polymer surfaces which are so modified can display enhanced heat sealability to accept bonding to other materials.
摘要翻译：半结晶聚合物可以通过照射使预定量的表面呈现准非晶态。如此改性的聚合物表面可以显示增强的热封性以接受与其它材料的粘合。

53. 发明授权

US4879176A Surface modification of semicrystalline polymers 失效
标题翻译：半结晶聚合物的表面改性
公开(公告)号：US4879176A
公开(公告)日：1989-11-07
申请号：US186813
申请日：1988-04-27
申请人： Andrew J. Ouderkirk , Douglas S. Dunn , Robert W. Warner
发明人： Andrew J. Ouderkirk , Douglas S. Dunn , Robert W. Warner
IPC分类号： B05D3/06 , B29C35/08 , B29C59/16 , B29C71/00 , C08J5/12 , C08J7/04
CPC分类号： C08J7/047 , B05D3/063 , B29C59/16 , B29C71/0063 , C08J5/121 , B29C2035/0827 , B29C2035/0838 , B29K2995/0039 , B29K2995/0041 , C08J2327/06 , C08J2367/02 , Y10T428/25 , Y10T428/265 , Y10T428/31 , Y10T428/3154 , Y10T428/31544 , Y10T428/31551 , Y10T428/31739 , Y10T428/31786 , Y10T428/31913 , Y10T428/31931 , Y10T428/31938
摘要： Semicrystalline polymers can have predetermined amounts of their surfaces rendered quasi-amorphous by irradiation. Polymer surfaces which are so modified can display enhanced ability to accept bonding to other materials.
摘要翻译：半结晶聚合物可以通过照射使预定量的表面呈现准非晶态。如此改性的聚合物表面可以显示增强的接受与其它材料粘结的能力。

54. 发明授权

US09414821B2 Vascular closure device with biodegradable anchor 有权
标题翻译：血管闭合装置与可生物降解锚
公开(公告)号：US09414821B2
公开(公告)日：2016-08-16
申请号：US12841895
申请日：2010-07-22
申请人： Liliana Atanasoska , David J. Sogard , Robert W. Warner , Michael Root , Rajesh Radhakrishnan , Mourad Rahi , Scott R. Smith , Jan Weber , Eric Petersen
发明人： Liliana Atanasoska , David J. Sogard , Robert W. Warner , Michael Root , Rajesh Radhakrishnan , Mourad Rahi , Scott R. Smith , Jan Weber , Eric Petersen
IPC分类号： A61B17/08 , A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00411 , A61B2017/00654 , A61B2017/00659
摘要： This disclosure pertains to controllably bioabsorbable devices, particularly anchors for vascular closure plugs and to methods of use thereof.
摘要翻译：本公开涉及可控制的生物可吸收装置，特别是用于血管闭塞塞的锚及其使用方法。

55. 发明授权

US09364678B2 Implantable electrodes containing polyoxometalate anions and methods of manufacture and use 有权
标题翻译：含有多金属氧酸盐阴离子的可植入电极及其制造和使用方法
公开(公告)号：US09364678B2
公开(公告)日：2016-06-14
申请号：US13166528
申请日：2011-06-22
申请人： Liliana Atanasoska , Jan Weber , Scott Schewe , Robert W. Warner
发明人： Liliana Atanasoska , Jan Weber , Scott Schewe , Robert W. Warner
IPC分类号： A61N1/372 , A61N1/05 , A61N1/36
CPC分类号： A61N1/372 , A61N1/05 , A61N1/0551 , A61N1/0553 , A61N1/36 , A61N1/37205
摘要： An implantable device includes at least one electrode comprising a conductive base and polyoxometalate anions disposed on or within the conductive base; and at least one conductor attached to the at least one electrode for conducting electrical energy to the at least one electrode.
摘要翻译：可植入装置包括至少一个电极，其包括设置在导电基底上或内部的导电基底和多金属氧酸盐阴离子; 以及至少一个连接到所述至少一个电极的导体，用于将电能传导到所述至少一个电极。

56. 发明授权

US08808726B2 Bioerodible endoprostheses and methods of making the same 有权
标题翻译：生物蚀刻内用假体及其制作方法
公开(公告)号：US08808726B2
公开(公告)日：2014-08-19
申请号：US11855499
申请日：2007-09-14
申请人： Liliana Atanasoska , Jan Weber , Robert W. Warner , Amy Grovender
发明人： Liliana Atanasoska , Jan Weber , Robert W. Warner , Amy Grovender
IPC分类号： A61F2/06 , A61L31/16 , A61L31/10 , A61L31/14 , A61F2/82
CPC分类号： A61L31/148 , A61F2/82 , A61F2210/0004 , A61L31/10 , A61L31/16 , A61L2300/802
摘要： Bioerodible endoprostheses and methods of making the endoprostheses are disclosed. In some embodiments, an endoprosthesis includes a member including a bioerodible material, and an antioxidant carried by the member. Examples of antioxidants include phenols.
摘要翻译：公开了生物蚀刻内假体和制造内用假体的方法。在一些实施例中，内假体包括包括生物腐蚀性材料的构件和由构件承载的抗氧化剂。抗氧化剂的实例包括酚类。

57. 发明授权

US08455088B2 Spun nanofiber, medical devices, and methods 有权
标题翻译：纺丝纳米纤维，医疗器械和方法
公开(公告)号：US08455088B2
公开(公告)日：2013-06-04
申请号：US11318027
申请日：2005-12-23
申请人： Scott R. Schewe , Michele L. Zoromski , Liliana L. Atanasoska , Robert W. Warner
发明人： Scott R. Schewe , Michele L. Zoromski , Liliana L. Atanasoska , Robert W. Warner
IPC分类号： C07F7/02
CPC分类号： D04H1/42 , A61L27/306 , A61L27/446 , A61L29/126 , A61L31/088 , A61L31/128 , A61L2400/12 , B82Y30/00 , C03B37/011 , D01D5/003 , D01F9/00 , D04H3/02 , D04H3/16 , Y10T428/249924 , Y10T428/24994 , Y10T428/249941
摘要： The present disclosure relates to compounds from which nanofibers can be produced, the resulting nanofibers produced from the compounds, and nanofiber reinforced polymers prepared using the nanofibers and a polymer. The compounds used in forming the nanofibers include chemical linkage moieties that are capable of forming non-covalent bonds with portions of the polymer so as to form the nanofiber reinforced polymers. The nanofiber reinforced polymers are useful as biomaterials in medical devices.
摘要翻译：本公开涉及可以从其制备纳米纤维的化合物，由化合物制备的所得纳米纤维，以及使用纳米纤维和聚合物制备的纳米纤维增强聚合物。用于形成纳米纤维的化合物包括能与聚合物部分形成非共价键以形成纳米纤维增强聚合物的化学连接部分。纳米纤维增强聚合物可用作医疗器械中的生物材料。

58. 发明授权

US08187623B2 Medical copolymers 有权
标题翻译：医用共聚物
公开(公告)号：US08187623B2
公开(公告)日：2012-05-29
申请号：US12491467
申请日：2009-06-25
申请人： J. Thomas Ippoliti , Scott Schewe , Robert W. Warner , Michele Zoromski
发明人： J. Thomas Ippoliti , Scott Schewe , Robert W. Warner , Michele Zoromski
IPC分类号： A61F2/00 , A61K9/14
CPC分类号： C08G61/08 , A61L31/06 , A61L31/10 , C08G61/12 , C08G2261/147 , C08G2261/3324 , C08G2261/3342 , C08G2261/418
摘要： Medical copolymers are provided which comprise (a) a polymer backbone comprising (i) a plurality of —C═C— groups within the polymer backbone, (ii) a plurality of —R9— groups within the polymer backbone, wherein R9 comprises a radical-substituted C2-C10 cyclic or heterocyclic group, or (iii) both a plurality of —C═C— groups and a plurality of —R9— groups within the polymer backbone, (b) a plurality of hydrocarbon-based pendant groups along the polymer backbone that comprise a saturated or unsaturated carbon chain of at least four carbons in length, and (c) a plurality of zwitterionic pendant groups along the polymer backbone that comprise a positively charged quaternary ammonium group and a negatively charged phosphate group. Methods of forming such copolymers, medical products that contain such copolymers, and methods of making such medical products are also disclosed.
摘要翻译：提供医疗共聚物，其包含（a）聚合物主链，其包含（i）聚合物主链内的多个-C≡C-基团，（ii）聚合物主链内的多个-R9-基团，其中R9包含基团 - 取代的C 2 -C 10环状或杂环基团，或（iii）聚合物主链内的多个-C≡C-基团和多个-R9-基团，（b）多个基于烃基的侧基包括长度为至少四个碳的饱和或不饱和碳链的聚合物主链，和（c）沿聚合物主链的多个两性离子侧基，其包含带正电荷的季铵基和带负电荷的磷酸基。还公开了形成这种共聚物的方法，含有这些共聚物的医药产品，以及制造这种医药产品的方法。

59. 发明申请

US20120101525A1 FIBROUS CONTAINMENT FOR HEMOSTASIS PLUG 审中-公开
标题翻译：用于HEMOSTASIS PLUG的FIBROUS容纳
公开(公告)号：US20120101525A1
公开(公告)日：2012-04-26
申请号：US13278910
申请日：2011-10-21
申请人： Mark L. Jenson , Jason P. Hill , James Q. Feng , David J. Sogard , Robert W. Warner , Patrick A. Haverkost
发明人： Mark L. Jenson , Jason P. Hill , James Q. Feng , David J. Sogard , Robert W. Warner , Patrick A. Haverkost
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/0404 , A61B2017/0417 , A61B2017/06185
摘要： A device for sealing an opening in a vessel includes an anchor attached to a suture. The anchor is inserted through the opening into the vessel, and the suture pulls the anchor against the vessel wall, forming a seal. A plug is inserted over the suture and is axially compressed toward the anchor, locking the elements in place. The suture is braided or woven outside of the anchor so that it may be stored and handled easily, and is unbraided, unwoven and/or untangled at its distal end inside the anchor, so that individual filaments within the suture may extend laterally within the anchor. The laterally extending filaments subtend a larger footprint within the anchor than a comparable footprint if the suture were to remain braided or tied into a knot within the anchor, which may more effectively distribute the retaining forces within the anchor.
摘要翻译：用于密封容器中的开口的装置包括附接到缝合线的锚固件。锚固件通过开口插入容器中，并且缝合线将锚固件拉靠在血管壁上，形成密封。将塞子插入缝合线上并朝向锚固件轴向压缩，将元件锁定就位。该缝合线被编织或编织在锚定体之外，使得其可以容易地储存和处理，并且在其锚固体内部的远端处是未被覆盖的，无纺的和/或解开的，使得缝合线内的单个细丝可以在锚定件内横向延伸。横向延伸的长丝在锚固体内对着较大的覆盖区域，而不是如果缝合线保持编织或连接到锚固体内的结，这可以更有效地将锚定力分配在锚固体内。

60. 发明授权

US08114148B2 Medical devices for delivery of therapeutic agent in conjunction with galvanic corrosion 失效
标题翻译：用于递送治疗剂与电化学腐蚀的医疗装置
公开(公告)号：US08114148B2
公开(公告)日：2012-02-14
申请号：US12489948
申请日：2009-06-23
申请人： Liliana Atanasoska , Jan Weber , Paul Grosso , Robert W. Warner , Kasyap V. Seethamraju
发明人： Liliana Atanasoska , Jan Weber , Paul Grosso , Robert W. Warner , Kasyap V. Seethamraju
IPC分类号： A61F2/82
CPC分类号： A61L31/022 , A61L31/10 , A61L31/14 , A61L31/148 , A61L31/16 , A61L2300/00
摘要： According to an aspect of the present invention, at least one ionic therapeutic agent is delivered from an implantable or insertable medical device that comprises an ion-conductive polymeric region that is disposed on a metallic region. The metallic region is in electrical contact with a dissimilar metallic region, such that a galvanic current is generated by the dissimilar metals when the device is implanted or inserted into a patient. Delivery of the ionic therapeutic agent from the ion-conductive polymeric region may be, for example, either accelerated or retarded by the galvanic current. According to another aspect of the present invention, implantable or insertable medical devices are provided which comprise: (a) a first metallic region having a first corrosion potential, (b) a second metallic region in electrical contact with the first metallic region and having a second corrosion potential that is greater than the first corrosion potential, and (c) a solid ion-conductive polymeric region, comprising an ion conducting polymer and an ionic therapeutic agent, disposed on the first metallic region, the second metallic region, or both.
摘要翻译：根据本发明的一个方面，至少一种离子治疗剂从可植入或可插入的医疗装置输送，其包括设置在金属区域上的离子导电聚合物区域。金属区域与异种金属区域电接触，使得当器件植入或插入患者体内时，异种金属产生电流。离子导电聚合物区域的离子治疗剂的递送可以例如由电流加速或延迟。根据本发明的另一方面，提供了可植入或可插入的医疗装置，其包括：（a）具有第一腐蚀电位的第一金属区域，（b）与第一金属区域电接触的第二金属区域，第二腐蚀电位大于第一腐蚀电位，和（c）固体离子传导聚合物区域，其包含离子导电聚合物和离子治疗剂，设置在第一金属区域，第二金属区域或两者上。

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