专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

51. 发明授权

US09879360B2 Microfluidic selection of library elements 有权
公开(公告)号：US09879360B2
公开(公告)日：2018-01-30
申请号：US12143272
申请日：2008-06-20
申请人： Emmanuel Delamarche , Robert Lovchik , Daniel J. Solis
发明人： Emmanuel Delamarche , Robert Lovchik , Daniel J. Solis
IPC分类号： C12M3/00 , C40B30/04 , C40B60/12 , G01N33/543 , B01L3/00
CPC分类号： C40B30/04 , B01J2219/00389 , B01J2219/00418 , B01J2219/00527 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00657 , B01J2219/00659 , B01J2219/00677 , B01J2219/00702 , B01J2219/00722 , B01J2219/00725 , B01J2219/0074 , B01L3/5025 , B01L3/5027 , B01L2300/0816 , B01L2300/0864 , B01L2300/087 , B01L2400/0487 , B01L2400/06 , C40B60/12 , G01N33/54366
摘要： Disclosed herein is a microfluidic device comprising a chip; a flow channel being disposed in the chip; the flow channel being in communication with an entry port and an exit port; the flow channel being operative to permit the flow of a library from the entry port to the exit port; a substrate; the substrate being disposed upon the chip; the substrate being operative to act as an upper wall for the flow channels; and a plurality of receptors; the plurality of receptors being disposed on the substrate; the plurality of receptors being operative to interact with an element from the library.

52. 发明申请

US20120283133A1 MICROFLUIDIC SELECTION OF LIBRARY ELEMENTS 审中-公开
标题翻译：微型选择图书馆元素
公开(公告)号：US20120283133A1
公开(公告)日：2012-11-08
申请号：US13552312
申请日：2012-07-18
申请人： Emmanuel Delamarche , Robert Lovchik , Daniel J. Solis
发明人： Emmanuel Delamarche , Robert Lovchik , Daniel J. Solis
IPC分类号： C40B30/04
CPC分类号： C40B30/04 , B01J2219/00389 , B01J2219/00418 , B01J2219/00527 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00657 , B01J2219/00659 , B01J2219/00677 , B01J2219/00702 , B01J2219/00722 , B01J2219/00725 , B01J2219/0074 , B01L3/5025 , B01L3/5027 , B01L2300/0816 , B01L2300/0864 , B01L2300/087 , B01L2400/0487 , B01L2400/06 , C40B60/12 , G01N33/54366
摘要： A microfluidic device includes a chip; a flow channel being disposed in the chip; the flow channel being in communication with an entry port and an exit port; the flow channel being operative to permit the flow of a library from the entry port to the exit port; a substrate; the substrate being disposed upon the chip; the substrate being operative to act as an upper wall for the flow channels; and a plurality of receptors; the plurality of receptors being disposed on the substrate; the plurality of receptors being operative to interact with an element from the library.
摘要翻译：微流体装置包括芯片; 流通道设置在芯片中; 所述流通道与入口和出口通信; 所述流动通道可操作以允许库从入口到出口的流动; 底物; 所述基板设置在所述芯片上; 所述基底可用作所述流动通道的上壁; 和多个受体; 所述多个受体被设置在所述基底上; 多个受体可操作以与来自文库的元件相互作用。

53. 发明申请

US20100176089A1 CONFINEMENT OF FLUIDS ON SURFACES 审中-公开
标题翻译：流体表面上的限制
公开(公告)号：US20100176089A1
公开(公告)日：2010-07-15
申请号：US12748847
申请日：2010-03-29
申请人： Emmanuel Delamarche , David Juncker , Heinz Schmid
发明人： Emmanuel Delamarche , David Juncker , Heinz Schmid
IPC分类号： C23F1/08 , C23F1/00
CPC分类号： B82Y30/00 , B01J19/0046 , B01J2219/00353 , B01J2219/00367 , B01J2219/00369 , B01J2219/0038 , B01J2219/00418 , B01J2219/00468 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00637 , B01J2219/00675 , B01J2219/00677 , B01J2219/00722 , B01J2219/00743 , C23F1/08 , C40B40/06 , C40B50/14 , C40B60/14
摘要： The invention is directed to a device for applying a fluid to a surface, the device comprising a first conduit for directing a flow of a first fluid towards the surface and a second conduit for directing a flow of a second fluid away from the surface, the first conduit being arranged relative to the second conduit such that in operation of the device the second fluid comprises substantially the first fluid, and wherein said first conduit comprises a first aperture and the second conduit comprises a second aperture, the first aperture arranged at a distance from the second aperture.
摘要翻译：本发明涉及一种用于将流体施加到表面的装置，该装置包括用于将第一流体的流动引向表面的第一导管和用于将第二流体的流动引导离开表面的第二导管，第一管道相对于第二管道布置，使得在装置的操作中，第二流体基本上包括第一流体，并且其中所述第一管道包括第一孔，第二管道包括第二孔，第一孔以一定距离布置从第二个孔。

54. 发明授权

US07695687B2 Capillary system for controlling the flow rate of fluids 有权
标题翻译：用于控制流体流量的毛细管系统
公开(公告)号：US07695687B2
公开(公告)日：2010-04-13
申请号：US11427811
申请日：2006-06-30
申请人： Emmanuel Delamarche , Heinz Schmid , David Juncker
发明人： Emmanuel Delamarche , Heinz Schmid , David Juncker
IPC分类号： B01L11/00 , B01L3/02 , G01N1/10 , B01D57/02
CPC分类号： B01L3/50273 , B01L2300/0636 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2300/161 , B01L2400/0406 , B01L2400/086 , Y10T436/2575
摘要： A capillary system for performing surface assays comprising a capillary pump containing at least two zones having different capillary pressures for obtaining controlled flow rate of liquids. The different pressure zones may be created by various means such as by creating posts in the walls of the capillary pump, by having different sized capillary of the different zones, by changing the wetting properties, by defining friction at the walls of the pump or by combinations of any of the above. The capillary system finds use in various surface assays and can be programmed for defining the volume and rate of liquid flowing through the test sites. A microfluidic chip containing assembly of programmed capillary systems for performing need based specific assays and modifications thereof.
摘要翻译：一种用于进行表面测定的毛细管系统，其包括含有至少两个具有不同毛细管压力的区域的毛细管泵，以获得受控的液体流速。不同的压力区可以通过各种方式产生，例如通过在不同区域的壁上形成不同尺寸的毛细管，通过改变润湿特性，通过在泵的壁处限定摩擦或通过以上任何一种的组合。毛细管系统可用于各种表面测定，并可编程为定义流经测试位点的液体的体积和速率。一种含有编程毛细管系统组件的微流体芯片，用于执行基于需要的具体测定及其修改。

55. 发明授权

US09012136B2 Detection of an analyte in a sample 有权
标题翻译：检测样品中的分析物
公开(公告)号：US09012136B2
公开(公告)日：2015-04-21
申请号：US12742996
申请日：2008-10-30
申请人： Emmanuel Delamarche , Daniel J. Solis
发明人： Emmanuel Delamarche , Daniel J. Solis
IPC分类号： C12Q1/00 , C12Q1/70 , C12Q1/68 , G01N33/53 , A61K49/00 , G01N33/543 , G01N33/536 , B01L3/00
CPC分类号： G01N33/56983 , B01L3/502753 , B01L3/502761 , B01L3/5029 , B01L2200/0668 , B01L2300/0654 , B01L2300/0681 , B01L2400/0406 , B01L2400/0688 , B01L2400/086 , G01N2333/11
摘要： There is provided mechanisms for the detection of an analyte in a sample. The mechanisms utilize at least a first measurement channel comprising a detection reactant corresponding to the analyte to be detected, and at least a microstructure associated with the first measurement channel. When the mechanisms are in use, the sample is introduced into the first measurement channel and propagated by way of the first measurement channel towards the microstructure. If the analyte is present in the sample, the analyte interacts with the detection reactant to form a networked product, and the microstructure is configured to filter the networked product.
摘要翻译：提供了用于检测样品中的分析物的机制。这些机构利用至少第一测量通道，其包含对应于待检测分析物的检测反应物，以及至少与第一测量通道相关联的微结构。当机构使用时，将样品引入第一测量通道并且通过第一测量通道朝向微结构传播。如果分析物存在于样品中，则分析物与检测反应物相互作用以形成网络产物，并且微结构被配置为过滤网络产物。

56. 发明授权

US08695641B2 Multilayer microfluidic probe head and method of fabrication thereof 有权
标题翻译：多层微流体探针头及其制造方法
公开(公告)号：US08695641B2
公开(公告)日：2014-04-15
申请号：US13561656
申请日：2012-07-30
申请人： Emmanuel Delamarche , Ute Drechsler , Robert Lovchik
发明人： Emmanuel Delamarche , Ute Drechsler , Robert Lovchik
IPC分类号： F15C1/06
CPC分类号： B01J19/0046 , B01J2219/00367 , B01J2219/00527 , B01J2219/00743 , B01L3/0241 , B01L3/502707 , B01L2300/0874 , B01L2300/0887 , Y10T29/494 , Y10T137/0318 , Y10T137/0402 , Y10T137/2224 , Y10T137/8359 , Y10T137/8593 , Y10T137/87153 , Y10T137/87885
摘要： A microfluidic probe head includes a first layer, a second layer, and a first tubing port extending from an upper face of the first layer. The first layer has a first via, enabling fluid communication between the first port and a lower face of the first layer. The second layer includes a first aperture on a face, and a first microchannel enabling fluid communication between an upper face of the second layer, facing the lower face of the first layer, and the first aperture. The head enables fluid communication between the first via and the first microchannel. At least a portion of the first microchannel is a groove open on the upper face of the second layer, closed by a portion of a lower face of a layer of the head. The probe head further comprises a second tubing port, a second via, a second aperture and a second microchannel.
摘要翻译：微流体探针头包括从第一层的上表面延伸的第一层，第二层和第一管口。第一层具有第一通孔，使得能够在第一端口和第一层的下表面之间进行流体连通。第二层包括面上的第一孔，以及第一微通道，其使第二层的上表面与第一层的下表面和第一孔之间能够流体连通。头部使得第一通孔和第一微通道之间能够流体连通。第一微通道的至少一部分是在第二层的上表面上开口的凹槽，由头部的一层的下表面的一部分封闭。探头还包括第二管口，第二通孔，第二孔和第二微通道。

57. 发明授权

US08680024B2 Methods for screening and arraying microrganisms such as viruses using subtractive contact printing background 有权
公开(公告)号：US08680024B2
公开(公告)日：2014-03-25
申请号：US13429929
申请日：2012-03-26
申请人： Sean R. Coyer , Emmanuel Delamarche , Daniel J. Solis
发明人： Sean R. Coyer , Emmanuel Delamarche , Daniel J. Solis
IPC分类号： C40B50/18
CPC分类号： G01N33/543 , B01J19/0046 , B01J2219/00382 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00659 , B01J2219/00677 , B01J2219/00725 , B01J2219/0074 , C40B60/08 , C40B60/12 , G01N33/6845 , G01N2333/005
摘要： Methods for screening and arranging microorganisms such as viruses in an array using subtractive contact printing are provided. In one embodiment, a method for forming an array of receptors for microorganisms comprises: patterning an array of structures on a first substrate to form a template on a surface of the first substrate; applying a receptor material to a face of a second substrate; and contacting the face of the second substrate with the template to remove a portion of the receptor material from the second substrate, thereby forming an array of receptors on the second substrate.

58. 发明申请

US20120214153A1 Detection of an Analyte in a Sample 有权
标题翻译：检测样品中的分析物
公开(公告)号：US20120214153A1
公开(公告)日：2012-08-23
申请号：US13459764
申请日：2012-04-30
申请人： Emmanuel Delamarche , Daniel J. Solis
发明人： Emmanuel Delamarche , Daniel J. Solis
IPC分类号： C12Q1/70 , G01N33/566 , C12Q1/02 , G01N21/00
CPC分类号： G01N33/56983 , B01L3/502753 , B01L3/502761 , B01L3/5029 , B01L2200/0668 , B01L2300/0654 , B01L2300/0681 , B01L2400/0406 , B01L2400/0688 , B01L2400/086 , G01N2333/11
摘要： There is provided mechanisms for the detection of an analyte in a sample. The mechanisms utilize at least a first measurement channel comprising a detection reactant corresponding to the analyte to be detected, and at least a microstructure associated with the first measurement channel. When the mechanisms are in use, the sample is introduced into the first measurement channel and propagated by way of the first measurement channel towards the microstructure. If the analyte is present in the sample, the analyte interacts with the detection reactant to form a networked product, and the microstructure is configured to filter the networked product.
摘要翻译：提供了用于检测样品中的分析物的机制。这些机构利用至少第一测量通道，其包含对应于待检测分析物的检测反应物，以及至少与第一测量通道相关联的微结构。当机构使用时，将样品引入第一测量通道并且通过第一测量通道朝向微结构传播。如果分析物存在于样品中，则分析物与检测反应物相互作用以形成网络产物，并且微结构被配置为过滤网络产物。

59. 发明授权

US08020586B2 One-step flow control for crossing channels 失效
标题翻译：跨越通道的一步式流量控制
公开(公告)号：US08020586B2
公开(公告)日：2011-09-20
申请号：US12329550
申请日：2008-12-06
申请人： Emmanuel Delamarche
发明人： Emmanuel Delamarche
IPC分类号： F15C1/04
CPC分类号： F16K99/0001 , F16K31/086 , F16K99/0046 , F16K2099/0084 , Y10T137/2213
摘要： In one embodiment of the present invention, an apparatus for one-step flow control at a micro-channel crossing comprises a first micro-channel and a second micro-channel, a plurality of magnetic valves, and a guiding magnet. The guiding magnet produces a proximal magnetic field gradient at a location of each of the plurality of magnetic valves when an operator places the guiding magnet in a vicinity of the chip. The vicinity of the chip comprises a plurality of guiding magnet position ranges. The operator repositions guiding magnet in order to actuate the plurality of magnetic valves simultaneously. Depending on the position of the guiding magnet, the passages are blocked or unblocked to stop or let the fluid flow in a given crossing.
摘要翻译：在本发明的一个实施例中，用于微通道交叉的一步流量控制的装置包括第一微通道和第二微通道，多个电磁阀和引导磁体。当操作者将引导磁体放置在芯片附近时，引导磁体在多个电磁阀的每一个的位置处产生近端磁场梯度。芯片附近包括多个引导磁体位置范围。操作者重新引导磁体以同时致动多个电磁阀。取决于导向磁体的位置，通道被阻塞或不阻挡以停止或使流体在给定的横穿中流动。

60. 发明授权

US07908906B2 Fluidic test apparatus and method 有权
标题翻译：流体测试装置和方法
公开(公告)号：US07908906B2
公开(公告)日：2011-03-22
申请号：US11468089
申请日：2006-08-29
申请人： Govindarajan Natarajan , Emmanuel Delamarche , Eric A Eckberg , James N Humenik , Kathleen A McGroddy-Goetz , Scott Partington , Christopher F Perrera , Marco G Trivella , Timothy M Wiwel
发明人： Govindarajan Natarajan , Emmanuel Delamarche , Eric A Eckberg , James N Humenik , Kathleen A McGroddy-Goetz , Scott Partington , Christopher F Perrera , Marco G Trivella , Timothy M Wiwel
IPC分类号： G01N13/04
CPC分类号： G01N13/04 , A61B2010/0067
摘要： An apparatus, system and method for determining the osmolarity of a fluid. The system includes an apparatus having: a chip with a substantially planar top surface; a first circuit portion and a second circuit portion, each having a plurality of redundant electrically conductive lines disposed on the top surface; and a gap disposed between the first circuit portion and the second circuit portion, wherein a circuit is created when a fluid sample bridges the gap and connects the first circuit portion and the second circuit portion.
摘要翻译：用于测定流体渗透压的装置，系统和方法。该系统包括具有：具有基本平坦的顶表面的芯片的装置; 第一电路部分和第二电路部分，每个具有设置在顶表面上的多个冗余导电线; 以及设置在第一电路部分和第二电路部分之间的间隙，其中当流体样品桥接间隙并连接第一电路部分和第二电路部分时产生电路。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式