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51. 发明授权

US07794959B2 Identification of bitter receptors for hydrolyzed soy protein 有权
标题翻译：鉴定水解大豆蛋白的苦味受体
公开(公告)号：US07794959B2
公开(公告)日：2010-09-14
申请号：US12053855
申请日：2008-03-24
申请人： Xiaodong Li , Hong Xu , Lan Zhang , Hanghui Liu , Keping Wu
发明人： Xiaodong Li , Hong Xu , Lan Zhang , Hanghui Liu , Keping Wu
IPC分类号： G01N33/567 , C07K14/705
CPC分类号： C12Q1/6895 , G01N33/5008 , G01N33/566 , G01N2500/00
摘要： The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds present in hydrolyzed soy protein derived materials. The invention further relates to the use of these T2R receptors in assays for identifying ligands that modulate the activation of these taste receptors by specific bitter ligands present in hydrolyzed soy protein materials and derivatives thereof and related compounds. These compounds may be used as additives and/or removed from soy-based foods, beverages, cosmetics and medicinals in order to modify (block) T2R-associated bitter taste elicited by bitter ligands present in hydrolyzed soy protein materials. Also these T2R ligands potentially may be used as therapeutics to treat and modulate hT2R1 or hT2R67 associated gastrointestinal and metabolic functions such as serum cholesterol levels as well as treat gastrointestinal and metabolic diseases such as eating disorders, food sensing, food absorption, obesity, diabetes, Crohn's disease, celiac disease, et al.
摘要翻译：本发明涉及T2R味觉受体家族中的特定人味受体对存在于水解大豆蛋白衍生物质中的特定苦味化合物的反应的发现。本发明还涉及这些T2R受体在用于鉴定通过水解大豆蛋白材料及其衍生物和相关化合物中存在的特定苦味配体调节这些味觉受体的活化的配体的测定中的用途。这些化合物可以用作添加剂和/或从大豆基食品，饮料，化妆品和药物中去除，以便改变（阻断）水解大豆蛋白材料中存在的苦配子引起的与T2R相关的苦味。此外，这些T2R配体可能被用作治疗和调节hT2R1或hT2R67相关的胃肠道和代谢功能如血清胆固醇水平以及治疗胃肠道和代谢疾病如饮食失调，食物感觉，食物吸收，肥胖，糖尿病，克罗恩病，乳糜泻等。

52. 发明申请

US20090215503A1 Apparatus and Method for Providing Hands-Free Operation of a Device 有权
标题翻译：提供设备免提操作的装置和方法
公开(公告)号：US20090215503A1
公开(公告)日：2009-08-27
申请号：US12430188
申请日：2009-04-27
申请人： Lan Zhang , Joseph E. Page, JR. , Barrett M. Kreiner
发明人： Lan Zhang , Joseph E. Page, JR. , Barrett M. Kreiner
IPC分类号： H04M1/00
CPC分类号： H04M1/6066 , H04M1/271 , H04M1/6505 , H04M2250/74
摘要： The present invention provides an apparatus and method for providing hands-free operation of a device. A hands-free adapter is provided that communicates with a device and a headset. The hands-free adapter allows a user to use voice commands so that the user does not have to handle the device. The hands-free adapter receives voice commands from the headset and translates the voice commands to commands recognized by the device. The hands-free adapter also monitors the device to detect device events and provides notice of the events to the user via the headset.
摘要翻译：本发明提供了一种用于提供设备的免提操作的装置和方法。提供与设备和耳机通信的免提适配器。免提适配器允许用户使用语音命令，以便用户不必处理该设备。免提适配器从耳机接收语音命令，并将语音命令转换为设备识别的命令。免提适配器还监视设备以检测设备事件，并通过耳机向用户提供事件的通知。

53. 发明申请

US20090112590A1 SYSTEM AND METHOD FOR IMPROVING INTERACTION WITH A USER THROUGH A DYNAMICALLY ALTERABLE SPOKEN DIALOG SYSTEM 有权
标题翻译：用于通过动态可更换的对讲机系统改进与用户交互的系统和方法
公开(公告)号：US20090112590A1
公开(公告)日：2009-04-30
申请号：US11929306
申请日：2007-10-30
申请人： Gregory Pulz , Harry E. Blanchard , Steven H. Lewis , Lan Zhang
发明人： Gregory Pulz , Harry E. Blanchard , Steven H. Lewis , Lan Zhang
IPC分类号： G10L15/00
CPC分类号： G10L15/187
摘要： Disclosed are systems and methods for dynamically interacting with a user through a spoken dialogue system. A method includes the steps of (1) receiving a user utterance, (2) analyzing the user utterance for a threshold determination of dialect, (3) generating a response that reflects an incremental implementation of the dialect, (4) further varying the perceived implementation of the dialect in subsequent responses by a process of: (a) receiving a subsequent user utterance, (b) determining a modified level of confidence in the dialect based at least in part from the subsequent utterance, (c) generating a subsequent response that implements an incremental variation according to the modified level of confidence.
摘要翻译：公开了用于通过口头对话系统与用户动态交互的系统和方法。一种方法包括以下步骤：（1）接收用户话语，（2）分析用户话语的阈值确定方法，（3）产生反映方言的增量实现的响应，（4）进一步改变所感知的在随后的响应中通过以下过程来实现方言：（a）接收随后的用户话语，（b）至少部分地根据随后的话语确定方言中的置信度的修改级别，（c）生成后续响应根据修改的置信水平实现增量变化。

54. 发明授权

US07332833B2 Switching circuit for master-slave feeding mode of low voltage power supply 失效
标题翻译：低压电源主从供电方式切换电路
公开(公告)号：US07332833B2
公开(公告)日：2008-02-19
申请号：US11002235
申请日：2004-12-03
申请人： JunKui Pan , HongBing Cheng , YuJian Qian , Lan Zhang
发明人： JunKui Pan , HongBing Cheng , YuJian Qian , Lan Zhang
IPC分类号： H02J7/00
CPC分类号： H02J1/108 , H02J9/06 , Y10T307/62
摘要： The present invention provides a switching circuit for the master-slave feeding mode of the low voltage power supply. The switching circuit utilizes the active switches as the switching devices, so that it can increase the switching speed, decrease the voltage drop and loss, being suitable to the low voltage circuits, and can judge or determine the master power supply and the back-up power supply, realizing the switching between the master and slave power supplies without interruption. The switching circuit of the invention improves the reliability of the system and has the simple structure and easy operation.
摘要翻译：本发明提供一种用于低压电源的主从供电模式的开关电路。开关电路利用有源开关作为开关器件，从而可以提高开关速度，降低电压降和损耗，适合于低压电路，并且可以判断或确定主电源和备用电源电源，不间断地实现主从电源之间的切换。本发明的开关电路提高了系统的可靠性，结构简单，操作方便。

55. 发明授权

US07305760B2 System and method for capacitive coupled via structures in information handling system circuit boards 有权
标题翻译：用于信息处理系统电路板中电容耦合通孔结构的系统和方法
公开(公告)号：US07305760B2
公开(公告)日：2007-12-11
申请号：US10924629
申请日：2004-08-24
申请人： Abeye Teshome , Lan Zhang
发明人： Abeye Teshome , Lan Zhang
IPC分类号： H01R43/00 , H05K13/00
CPC分类号： H05K1/0216 , H05K1/0263 , H05K1/112 , H05K1/162 , H05K2201/0792 , H05K2201/09309 , H05K2201/10734 , Y10T29/49128 , Y10T29/49169
摘要： Power supplied to an information handling system electronic component through a circuit board has component package inductance parasitic effects compensated by configuring connections to the electronic component to have increased parasitic capacitance. For instance, power and ground vias that connect a processor to power and ground planes of the circuit board are aligned to create a desired parasitic capacitance that reduces the impact of parasitic inductance relating to signal compensation, power delivery and high speed decoupling. The desired distributed capacitance is modeled by altering the radius associated with the equivalent line charge of the power via, the distance associated with the line charges between power and ground vias, and the via barrel length.
摘要翻译：通过电路板提供给信息处理系统电子元件的功率具有通过配置与电子元件的连接以补偿寄生电容的组件封装电感寄生效应。例如，将处理器连接到电路板的电源和接地平面的电源和接地通孔对准以产生期望的寄生电容，其减少与信号补偿，功率输送和高速去耦合有关的寄生电感的影响。期望的分布电容通过改变与功率通孔的等效线电荷相关联的半径，与电源和接地通孔之间的线路电荷相关联的距离以及通孔筒长度来建模。

56. 发明申请

US20060135214A1 Apparatus and method for providing hands-free operation of a device 有权
公开(公告)号：US20060135214A1
公开(公告)日：2006-06-22
申请号：US11354198
申请日：2006-02-14
申请人： Lan Zhang , Joseph Page , Barrett Kreiner
发明人： Lan Zhang , Joseph Page , Barrett Kreiner
IPC分类号： H04M1/00
CPC分类号： H04M1/6066 , H04M1/271 , H04M1/6505 , H04M2250/74
摘要： The present invention provides an apparatus and method for providing hands-free operation of a device. A hands-free adapter is provided that communicates with a device and a headset. The hands-free adapter allows a user to use voice commands so that the user does not have to handle the device. The hands-free adapter receives voice commands from the headset and translates the voice commands to commands recognized by the device. The hands-free adapter also monitors the device to detect device events and provides notice of the events to the user via the headset.

57. 发明申请

US20050127882A1 Switching circuit for master-slave feeding mode of low voltage power supply 失效
标题翻译：低压电源主从供电方式切换电路
公开(公告)号：US20050127882A1
公开(公告)日：2005-06-16
申请号：US11002235
申请日：2004-12-03
申请人： JunKui Pan , HongBing Cheng , YuJian Qian , Lan Zhang
发明人： JunKui Pan , HongBing Cheng , YuJian Qian , Lan Zhang
IPC分类号： G05F1/40 , H02J9/04 , H02J9/06
CPC分类号： H02J1/108 , H02J9/06 , Y10T307/62
摘要： The present invention provides a switching circuit for the master-slave feeding mode of the low voltage power supply. The switching circuit utilizes the active switches as the switching devices, so that it can increase the switching speed, decrease the voltage drop and loss, being suitable to the low voltage circuits, and can judge or determine the master power supply and the back-up power supply, realizing the switching between the master and slave power supplies without interruption. The switching circuit of the invention improves the reliability of the system and has the simple structure and easy operation.
摘要翻译：本发明提供一种用于低压电源的主从供电模式的开关电路。开关电路利用有源开关作为开关器件，从而可以提高开关速度，降低电压降和损耗，适合于低压电路，并且可以判断或确定主电源和备用电源电源，不间断地实现主从电源之间的切换。本发明的开关电路提高了系统的可靠性，结构简单，操作方便。

58. 发明授权

US06801880B2 System and method for minimizing a loading effect of a via by tuning a cutout ratio 有权
标题翻译：通过调整切割比来最小化通孔的负载效应的系统和方法
公开(公告)号：US06801880B2
公开(公告)日：2004-10-05
申请号：US10187927
申请日：2002-07-02
申请人： Lan Zhang , Abeye Teshome
发明人： Lan Zhang , Abeye Teshome
IPC分类号： G06F1750
CPC分类号： H05K1/0216 , H05K1/116 , H05K3/429 , H05K2201/09718 , H05K2201/09781 , H05K2203/171 , Y10T29/49004
摘要： An information handling system that includes a circuit board for mounting and coupling components of the information handling system. The circuit board includes a trace, a via coupled to the trace, and a cutout region surrounding the via and having a first diameter selected to minimize a loading effect of a via on a signal conveyed on the trace.
摘要翻译：一种信息处理系统，包括用于安装和耦合信息处理系统的组件的电路板。电路板包括迹线，耦合到迹线的通孔和围绕通孔的切除区域，并且具有选择的最小直径，以最小化通孔对在迹线上传送的信号的负载效应。

59. 发明申请

US20220280636A1 ANTIGENIC GLYCOPROTEIN E POLYPEPTIDES, COMPOSITIONS, AND METHODS OF USE THEREOF 有权
公开(公告)号：US20220280636A1
公开(公告)日：2022-09-08
申请号：US17626206
申请日：2020-07-14
申请人： Arthur FRIDMAN , Jennifer Dawn GALLI , Dai WANG , Lan ZHANG , Merck Sharp & Dohme Corp.
发明人： Arthur Fridman , Jennifer Dawn Galli , Dai Wang , Lan Zhang
IPC分类号： A61K39/245 , C12N7/00
摘要： The disclosure relates to HSV glycoprotein E antigenic peptide constructs and HSV protein vaccines, as well as methods of using the vaccines and compositions comprising the vaccines. The present invention directed to immunogenic polypeptides of use for a vaccine against Herpes Simplex Vims (HSV). The polypeptides are glycoprotein E peptides that are mutated to reduce their binding to antibody Fc domain.

60. 发明授权

US08871253B2 Liposome having inner water phase containing sulfobutyl ether cyclodextrin salt 有权
标题翻译：脂质体内含水相，含有磺丁基醚环糊精盐
公开(公告)号：US08871253B2
公开(公告)日：2014-10-28
申请号：US13502776
申请日：2010-10-26
申请人： Chunlei Li , Lan Zhang , Caixia Wang , Li Zhang , Dongmin Shen , Yanhui Li , Xian Xiu , Min Liang , Yongfeng Li
发明人： Chunlei Li , Lan Zhang , Caixia Wang , Li Zhang , Dongmin Shen , Yanhui Li , Xian Xiu , Min Liang , Yongfeng Li
IPC分类号： A61K9/127 , A61K31/475 , A61K31/4745 , A61P35/00 , B01J13/18 , A61K31/724 , A61K9/00 , A61K9/50 , A61K45/06 , A61K47/40
CPC分类号： A61K9/127 , A61K9/0019 , A61K9/1271 , A61K9/5089 , A61K31/4745 , A61K31/475 , A61K31/724 , A61K45/06 , A61K47/40 , A61K2300/00
摘要： A liposome comprising bilayer and inner water phase is disclosed. Said inner water phase contains sulfobutyl ether cyclodextrin and active compound. Said sulfobutyl ether cyclodextrin is sulfobutyl ether α-cyclodextrin, sulfobutyl ether β-cyclodextrin, or sulfobutyl ether γ-cyclodextrin.
摘要翻译：公开了包含双层和内部水相的脂质体。所述内水相含有磺丁基醚环糊精和活性化合物。所述磺丁基醚环糊精是磺丁基醚α-环糊精，磺丁基醚和环糊精，或磺丁基醚γ-环糊精。

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