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51. 发明申请

US20070203802A1 METHOD FOR COLLECTING, TESTING AND DISTRIBUTING MILK 审中-公开
标题翻译：收集，测试和分配乳制品的方法
公开(公告)号：US20070203802A1
公开(公告)日：2007-08-30
申请号：US11679546
申请日：2007-02-27
申请人： Elena Medo , Martin Lee , David Rechtman
发明人： Elena Medo , Martin Lee , David Rechtman
IPC分类号： G06Q30/00
CPC分类号： G06Q10/06 , G06Q10/08 , G06Q30/0601
摘要： The disclosure is related generally to a method for facilitating the collection and distribution of milk over a computer network among a milk provider, a milk company and a milk distribution center.
摘要翻译：本公开一般涉及一种用于在牛奶供应商，牛奶公司和牛奶分配中心之间通过计算机网络收集和分配牛奶的方法。

52. 发明申请

US20060258977A1 Autoflush syringe 有权
标题翻译：自动冲洗注射器
公开(公告)号：US20060258977A1
公开(公告)日：2006-11-16
申请号：US11120906
申请日：2005-05-02
申请人： Martin Lee
发明人： Martin Lee
IPC分类号： A61M37/00
CPC分类号： A61M5/31596 , A61M2005/1787 , A61M2005/31508 , A61M2005/31598
摘要： A two-chambered, sequentially injectable syringe is disclosed. The syringe has two concentric barrels, substantially cylindrical in shape. The outer barrel has an open end adapted for receiving an inner barrel/first piston. The inner barrel/first piston contains a flushing liquid. The syringe has a second piston slidably movable in the inner barrel and a latching mechanism that can alternate between a locked configuration and an unlocked configuration. In the locked configuration, the latching mechanism prevents the second piston from substantially all longitudinal movement relative to the inner barrel. In the unlocked configuration, the latching mechanism permits longitudinal motion of the second piston within the inner barrel.
摘要翻译：公开了一种两室式顺序注射的注射器。注射器具有两个同心圆筒，大致圆柱形。外筒具有适于容纳内筒/第一活塞的开口端。内桶/第一活塞包含冲洗液。注射器具有可在内筒中可滑动地移动的第二活塞和可在锁定构型和解锁构型之间交替的闩锁机构。在锁定构造中，闩锁机构防止第二活塞相对于内筒几乎全部纵向移动。在解锁构造中，闩锁机构允许第二活塞在内筒内的纵向运动。

53. 发明申请

US20060127906A1 Detection system 审中-公开
标题翻译：检测系统
公开(公告)号：US20060127906A1
公开(公告)日：2006-06-15
申请号：US10530980
申请日：2003-10-10
申请人： Martin Lee , Mark Basche , Tom Brown
发明人： Martin Lee , Mark Basche , Tom Brown
IPC分类号： C12Q1/68 , C07H21/04 , C07H17/02
CPC分类号： C12Q1/6818 , C12Q2565/101 , C12Q2563/173
摘要： A method for detecting the presence of a target nucleic acid sequence in a sample, said method comprising: (a) adding to a sample suspected of containing said target nucleic acid sequence, a fluorescently labelled probe specific for said target sequence, and DNA duplex binding agent which can absorb fluorescent energy from the fluorescent label on the probe bur which does not emit visible light, (b) subjecting the thus formed mixture to an amplification reaction in which target nucleic acid is amplified, (c) subjecting said sample to conditions under which the said probe hybridises to the target sequence, and (d) monitoring fluorescence from said sample. This method can be used for example to monitor amplification reactions such as PCR reactions, such that the amount of target sequence present in the sample may be determined. Additionally or alternatively, it may be used to generate duplex destabilisation data such as melt hyteresis information for amplification monitoring or for detection and quantification of polymorphisms or allelic variation, and so is useful in genetic diagnosis.
摘要翻译：一种用于检测样品中靶核酸序列的存在的方法，所述方法包括：（a）向怀疑含有所述靶核酸序列的样品中加入对所述靶序列特异性的荧光标记的探针和DNA双链体结合可以从不发射可见光的探针头上的荧光标记吸收荧光能的试剂，（b）使由此形成的混合物经受扩增反应，其中靶核酸被扩增，（c）使所述样品经受所述探针与目标序列杂交，和（d）监测来自所述样品的荧光。该方法可用于例如监测扩增反应如PCR反应，使得可以确定样品中存在的靶序列的量。另外或替代地，其可以用于产生双链不稳定数据，例如用于扩增监测的融合信息信息或用于多态性或等位基因变异的检测和定量，因此在遗传诊断中是有用的。

54. 发明申请

US20060108533A1 Detector array for imaging system and method of making same 失效
标题翻译：用于成像系统的检测器阵列及其制造方法
公开(公告)号：US20060108533A1
公开(公告)日：2006-05-25
申请号：US10996261
申请日：2004-11-23
申请人： Kevin McEvoy , James Vartuli , Stephen Tedeschi , Steven Duclos , Martin Lee , Venkat Venkataramani , James Brewer , Robert Lyons , Mohandas Nayak
发明人： Kevin McEvoy , James Vartuli , Stephen Tedeschi , Steven Duclos , Martin Lee , Venkat Venkataramani , James Brewer , Robert Lyons , Mohandas Nayak
IPC分类号： G01T1/24
CPC分类号： G01T1/20 , G01T1/2018
摘要： A method of manufacturing a detector array for an imaging system, the method comprising providing a pixelated scintillator having a plurality of lost molded pixels comprising a scintillator material adapted to detect radiation.
摘要翻译：一种制造用于成像系统的检测器阵列的方法，所述方法包括提供具有多个丢失的模制像素的像素化闪烁体，所述多个丢失模制像素包括适于检测辐射的闪烁体材料。

55. 发明申请

US20060024843A1 Assay device 有权
标题翻译：测定装置
公开(公告)号：US20060024843A1
公开(公告)日：2006-02-02
申请号：US11188799
申请日：2005-07-26
申请人： Martin Lee , Zvi Greenberg , Eitan Rogel
发明人： Martin Lee , Zvi Greenberg , Eitan Rogel
IPC分类号： G01N33/558
CPC分类号： B01L3/5023 , B01L2200/027 , B01L2300/0825 , B01L2400/0683 , Y10T436/2575
摘要： A device for carrying out a lateral flow assay on a sample comprising: (a) a sample containing unit comprising a sample container, said sample container being closed off at one end by a bottom wall, said bottom wall having a hole sealed by a plug; and (b) a housing located under said sample container and capable of holding a test strip, said sample containing unit and said housing being coupled so as to allow rotation one relative to the other, said housing comprising a cutting arrangement capable of cutting said plug; wherein rotation of said sample containing unit and said housing one relative to the other results in said cutting arrangement cutting said plug, thereby unplugging the hole in said bottom wall. Also disclosed is a method for determining the presence or absence of an analyte in a sample, using the device.
摘要翻译：一种用于对样品进行横向流动测定的装置，包括：（a）包含样品容器的样品容纳单元，所述样品容器在一端由底壁封闭，所述底壁具有由插塞密封的孔 ; 和（b）位于所述样品容器下方并且能够保持测试条的壳体，所述样品容纳单元和所述壳体联接成允许相对于另一个旋转，所述壳体包括能够切割所述插塞的切割装置 ; 其中所述样品容纳单元和所述壳体相对于另一个的旋转导致所述切割装置切割所述塞子，从而拔掉所述底壁中的孔。还公开了使用该装置来确定样品中有无分析物的方法。

56. 发明申请

US20060002826A1 Sampling apparatus 审中-公开
标题翻译：取样装置
公开(公告)号：US20060002826A1
公开(公告)日：2006-01-05
申请号：US10529608
申请日：2003-10-02
申请人： Martin Lee , David Squirrell , Michael Best , Brian Croft
发明人： Martin Lee , David Squirrell , Michael Best , Brian Croft
IPC分类号： B01L3/00
CPC分类号： G01N1/34 , G01F11/286 , G01N1/14 , G01N1/18
摘要： This invention relates to a method and associated apparatus for isolating a known volume of sample solution comprising: (i) taking an apparatus comprising a first chamber with a sealing means, a second chamber, wherein said first and said second chamber are connected via a duct and collecting the sample solution into the first chamber of the apparatus; and (ii) pumping a pre-determined known volume of the sample solution into the second chamber of the apparatus. The sample solution of the present invention preferably comprises a nucleic acid target material. This invention also relates to a single integrated apparatus and a kit capable of performing the same.
摘要翻译：本发明涉及一种用于分离已知体积的样品溶液的方法和相关装置，包括：（i）采取包括具有密封装置的第一室的设备，第二室，其中所述第一室和所述第二室经由导管并将样品溶液收集到装置的第一室中; 和（ii）将预先确定的已知体积的样品溶液泵送到设备的第二室中。本发明的样品溶液优选包含核酸靶材料。本发明还涉及能够执行相同的单个集成装置和套件。

57. 发明申请

US20050286050A1 Real-time through lens image measurement system and method 审中-公开
标题翻译：实时透镜图像测量系统及方法
公开(公告)号：US20050286050A1
公开(公告)日：2005-12-29
申请号：US10882131
申请日：2004-06-29
申请人： Bausan Yuan , Martin Lee , Nobutaka Magome , Hidemi Kawai
发明人： Bausan Yuan , Martin Lee , Nobutaka Magome , Hidemi Kawai
IPC分类号： G01B11/00 , G03F7/20
CPC分类号： G03F7/70591
摘要： Embodiments of the present invention are directed to an apparatus and a method for through lens measurement for a projection system. In one embodiment, an apparatus for through lens image measurement comprises a projection lens housing containing lens elements therein, and a reflective member having a center of curvature on a first plane. The reflective member is attached to the lens housing. An optical system includes a light source, a position detector, and one or more optical elements. The optical system is attached to the lens housing and configured to direct a light from the light source through the lens elements to the reflective member which reflects the light back through the lens elements and toward the position detector. The position detector is configured to detect any image shift at the first plane due to misalignment of the lens elements with respect to the lens housing.
摘要翻译：本发明的实施例涉及一种用于投影系统的透镜测量的装置和方法。在一个实施例中，用于透镜图像测量的装置包括在其中容纳透镜元件的投影透镜壳体和在第一平面上具有曲率中心的反射构件。反射构件附接到透镜壳体。光学系统包括光源，位置检测器和一个或多个光学元件。光学系统附接到透镜壳体并且被配置为将来自光源的光通过透镜元件引导到反射构件，反射构件将光反射回透镜元件并朝向位置检测器。位置检测器被配置为由于透镜元件相对于透镜壳体的未对准而检测在第一平面处的任何图像偏移。

58. 发明申请

US20050112647A1 Detection system 审中-公开
标题翻译：检测系统
公开(公告)号：US20050112647A1
公开(公告)日：2005-05-26
申请号：US10958377
申请日：2004-10-06
申请人： Martin Lee , Roderick Fuerst
发明人： Martin Lee , Roderick Fuerst
IPC分类号： G01N33/50 , C12N15/09 , C12Q1/68 , C12Q1/6818 , C12Q1/6823
CPC分类号： C12Q1/6818 , C12Q1/6823 , Y10S436/80 , Y10T436/143333 , C12Q2563/107 , C12Q2561/113 , C12Q2527/107 , C12Q2563/173
摘要： A method for detecting the presence of a target nucleic acid sequence in a sample, said method comprising: (a) adding to a sample suspected of containing said target nucleic acid sequence, a probe specific for said target sequence and DNA duplex binding agent, said probe comprising a reactive molecule able to absorb fluorescence from or donate fluorescent energy to said DNA duplex binding agent, (b) subjecting the thus formed mixture to an amplification reaction in which target nucleic acid is amplified, (c) subjecting said sample to conditions under which the said probe hybridizes to the target sequence, and (d) monitoring fluorescence from said sample. This method can be used for example to monitor amplification reactions such as PCR reactions, such that the amount of target sequence present in the sample may be determined. Additionally or alternatively, it may be used to generate duplex destabilization data such as melt hysteresis information for amplification monitoring or for detection and quantitation of polymorphisms or allelic variation, and so is useful in genetic diagnosis.
摘要翻译：一种用于检测样品中靶核酸序列的存在的方法，所述方法包括：（a）向疑似含有所述靶核酸序列的样品，特异于所述靶序列的探针和DNA双链体结合剂加入所述探针，其包含能够从所述DNA双链体结合剂吸收荧光能量或向其提供荧光能量的反应性分子，（b）使由此形成的混合物经受扩增反应，其中靶核酸被扩增，（c）使所述样品经受所述探针与目标序列杂交，和（d）监测来自所述样品的荧光。该方法可用于例如监测扩增反应如PCR反应，使得可以确定样品中存在的靶序列的量。另外或替代地，其可以用于产生双相不稳定数据，例如用于放大监测的熔体滞后信息或用于多态性或等位基因变异的检测和定量，因此在遗传诊断中是有用的。

59. 发明申请

US20050082261A1 AN APPARATUS AND METHOD FOR MACHINING IN CONFINED SPACES 有权
标题翻译：用于在限定空间中加工的装置和方法
公开(公告)号：US20050082261A1
公开(公告)日：2005-04-21
申请号：US10605632
申请日：2003-10-15
申请人： Martin Lee , John Sassatelli , Todd Fischer , Dennis Roberts
发明人： Martin Lee , John Sassatelli , Todd Fischer , Dennis Roberts
IPC分类号： B23H7/26 , B23H9/00 , B23H9/10 , B23H9/14 , B23H11/00 , B23H1/00
CPC分类号： B23H9/00 , B23H7/26 , B23H7/265 , B23H9/14
摘要： A machining apparatus comprising: a discharge machining head assembly; and an electromagnet configured to support the head assembly in a position to machine an area. A method for machining comprising: attaching a machining tool to a surface; positioning a drill electrode to a work piece; and drilling the work piece with the machining tool.
摘要翻译：一种加工装置，包括：排出加工头组件; 以及构造成将头部组件支撑在加工区域的位置的电磁体。一种加工方法，包括：将加工工具附接到表面; 将钻孔电极定位到工件上; 并用加工工具钻出工件。

60. 发明申请

US20050029462A1 Monolithic structure for x-ray CT collimator 有权
标题翻译： x射线CT准直器的单片结构
公开(公告)号：US20050029462A1
公开(公告)日：2005-02-10
申请号：US10633969
申请日：2003-08-04
申请人： Robert Lyons , Martin Lee , Venkat Venkataramani , Clifford Bueno , James LeBlanc , James Vartuli , Charies Greskovich , Stephen Bancheri
发明人： Robert Lyons , Martin Lee , Venkat Venkataramani , Clifford Bueno , James LeBlanc , James Vartuli , Charies Greskovich , Stephen Bancheri
IPC分类号： G01T1/164 , G01T1/20
CPC分类号： G01T1/1648
摘要： A conversion device for use in an imaging system is provided. The conversion device includes a first perforated plate portion forming a plurality of collimator channels separated by a plurality of thin collimator walls. A second perforated plate portion forming a plurality of scintillator channels separated by a plurality of thin scintillator walls is attached to the first perforated plate portion. A reflective coating is applied to the inside scintillator surface of the plurality of thin scintillator walls. A scintillator material is filled into the plurality of scintillator channels.
摘要翻译：提供了一种用于成像系统中的转换装置。转换装置包括形成由多个薄的准直器壁隔开的多个准直器通道的第一多孔板部分。形成由多个薄闪烁体壁隔开的多个闪烁体通道的第二穿孔板部分附接到第一多孔板部分。将反射涂层施加到多个薄闪烁体壁的内部闪烁体表面。闪烁体材料被填充到多个闪烁体通道中。

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